学校法人順天堂　研究者情報データベース:::研究業績詳細:::

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研究業績詳細

曾根大地（ソネダイチ）

研究テーマ	てんかん、神経画像、認知症、精神神経疾患、核医学
研究業績（論文）	英文原著論文 (First Author) 32. Neuropsychiatric symptoms and neuroimaging-based brain age in mild cognitive impairment and early dementia: A multicenter study. Sone D, Beheshti I, Tagai K, Kameyama H, Takasaki E, Kashibayashi T, Takahashi R, Ishii K, Kanemoto H, Ikeda M, Shigeta M, Shinagawa S, Kazui H. Psychiatry Clin Neurosci. 2025;79(4):158-164. doi: 10.1111/pcn.13777 31. Estimated Disease Progression Trajectory of White Matter Disruption in Unilateral Temporal Lobe Epilepsy: A Data-Driven Machine Learning Approach. Sone D, Sato N, Shigemoto Y, Beheshti I, Kimura Y, Matsuda H. Brain Sci. 2024;14(10):992. doi: 10.3390/brainsci14100992 30. White matter brain-age in diverse forms of epilepsy and interictal psychosis. Sone D, Beheshti I, Shigemoto Y, Kimura Y, Sato N, Matsuda H. Sci Rep. 2024;14(1):19156. doi: 10.1038/s41598-024-70313-w 29. Disease Progression Patterns of Brain Morphology in Schizophrenia: More Progressed Stages in Treatment Resistance. Sone D, Young A, Shinagawa S, Tsugawa S, Iwata Y, Tarumi R, Ogyu K, Honda S, Ochi R, Matsushita K, Ueno F, Hondo N, Koreki A, Torres-Carmona E, Mar W, Chan N, Koizumi T, Kato H, Kusudo K, de Luca V, Gerretsen P, Remington G, Onaya M, Noda Y, Uchida H, Mimura M, Shigeta M, Graff-Guerrero A, Nakajima S. Schizophr Bull. 2024;50(2):393-402. doi: 10.1093/schbul/sbad164 28. Contribution of the μ-opioid receptor system to affective disorders in temporal lobe epilepsy: a bidirectional relationship? Sone D, Galovic M, Myers J, Leonhardt G, Rabiner I, Duncan JS, Koepp MJ, Foong J. Epilepsia. 2023;64(2):420-429. doi: 10.1111/epi.17463 27. Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis. Sone D, Sato N, Shigemoto Y, Kimura Y, Matsuda H. Epilepsia Open. 2022;7(4):657-664. doi: 10.1002/epi4.12645 26. Neuroimaging-derived brain age is associated with life satisfaction in cognitively unimpaired elderly: A community-based study. Sone D, Beheshti I, Shinagawa S, Niimura H, Kobayashi N, Kida H, Shikimoto R, Noda Y, Nakajima S, Bun S, Mimura M, Shigeta M. Transl Psychiatry. 2022;12(1):22. doi: 10.1038/s41398-022-01793-5 25. Optimal Surgical Extent for Memory and Seizure Outcome in Temporal Lobe Epilepsy. Sone D, Ahmad M, Thompson PJ, Baxendale S, Vos SB, Xiao F, de Tisi J, McEvoy AW, Miserocchi A, Duncan JS, Koepp MJ, Galovic M. Ann Neurol. 2022;91(1):131-144. doi: 10.1002/ana.26266 24. Quantitative analysis of double inversion recovery and FLAIR signals in temporal lobe epilepsy. Sone D, Sato N, Kimura Y, Maikusa N, Shigemoto Y, Matsuda H. Epilepsy Res. 2021;170:106540. doi: 10.1016/j.eplepsyres.2020.106540 23. Association between neurite metrics and tau/inflammatory pathology in Alzheimer’s disease. Sone D, Shigemoto Y, Ogawa M, Maikusa N, Okita K, Takano H, Kato K, Sato N, Matsuda H. Alzheimers Dement (Amst). 2020;12(1):e12125. doi: 10.1002/dad2.12125 22. Disrupted White Matter Integrity and Structural Brain Networks in Temporal Lobe Epilepsy With and Without Interictal Psychosis. Sone D, Sato N, Shigemoto Y, Kimura Y, Maikusa N, Ota M, Foong J, Koepp M, Matsuda H. Front Neurol. 2020;11:556569. doi: 10.3389/fneur.2020.556569 21. Neuroimaging-based brain-age prediction in diverse forms of epilepsy: a signature of psychosis and beyond. Sone D, Beheshti I, Maikusa N, Ota M, Kimura Y, Sato N, Koepp M, Matsuda H. Mol Psychiatry. 2021;26(3):825-834. doi: 10.1038/s41380-019-0446-9 20. Widely Impaired White Matter Integrity and Altered Structural Brain Networks in Psychogenic Non-Epileptic Seizures. Sone D, Sato N, Ota M, Kimura Y, Matsuda H. Neuropsychiatr Dis Treat. 2019;15:3549-3555. doi: 10.2147/NDT.S235159 19. Similar and Differing Distributions Between 18F-FDG-PET and Arterial Spin Labeling Imaging in Temporal Lobe Epilepsy. Sone D, Maikusa N, Sato N, Kimura Y, Ota M, Matsuda H. Front Neurol. 2019;10:318. doi: 10.3389/fneur.2019.00318 18. Reduced resilience of brain gray matter networks in idiopathic generalized epilepsy: A graph-theoretical analysis. Sone D, Watanabe M, Maikusa N, Sato N, Kimura Y, Enokizono M, Okazaki M, Matsuda H. PLoS One. 2019;14(2):e0212494. doi: 10.1371/journal.pone.0212494 17. Abnormal neurite density and orientation dispersion in unilateral temporal lobe epilepsy detected by advanced diffusion imaging. Sone D, Sato N, Ota M, Maikusa N, Kimura Y, Matsuda H. Neuroimage Clin. 2018;20:772-782. doi: 10.1016/j.nicl.2018.09.017 16. Voxel-based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) on 3-tesla Normal Database: Diagnostic Accuracy in Two Independent Cohorts with Early Alzheimer's Disease. Sone D, Imabayashi E, Maikusa N, Ogawa M, Sato N, Matsuda H; Japanese-Alzheimer’s Disease Neuroimaging Initiative. Aging Dis. 2018;9(4):755-760. doi: 10.14336/AD.2017.0818 15. Brain morphological and microstructural features in cryptogenic late-onset temporal lobe epilepsy: a structural and diffusion MRI study. Sone D, Sato N, Kimura Y, Watanabe Y, Okazaki M, Matsuda H. Neuroradiology. 2018;60(6):635-641. doi: 10.1007/s00234-018-2019-z 14. Marked accumulation of oligodendroglia-like cells in temporal lobe epilepsy with amygdala enlargement and hippocampal sclerosis. Sone D, Ikemura M, Saito Y, Taniguchi G, Kunii N. Neuropathology. 2018;38(2):154-158. doi: 10.1111/neup.12410 13. Subtle abnormality in neurite dispersion in idiopathic generalized epilepsy detected by an advanced diffusion imaging technique. Sone D, Watanabe M, Ota M, Imabayashi E, Rokicki J, Maikusa N, Sugiyama A, Maekawa T, Enokizono M, Kimura Y, Matsuda H, Sato N. Epilepsy & Seizure. 2018;10:33-43. doi: 10.3805/eands.10.33 12. Noninvasive detection of focal brain hyperthermia related to continuous epileptic activities using proton MR spectroscopy. Sone D, Ikegaya N, Takahashi A, Sumida K, Ota M, Saito T, Kimura Y, Matsuda H, Sato N. Epilepsy Res. 2017;138:1-4. doi: 10.1016/j.eplepsyres.2017.10.001 11. Regional tau deposition and subregion atrophy of medial temporal structures in early Alzheimer's disease: A combined positron emission tomography/magnetic resonance imaging study. Sone D, Imabayashi E, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Matsuda H. Alzheimers Dement (Amst). 2017;9:35-40. doi: 10.1016/j.dadm.2017.07.001 10. Thalamic hypoperfusion and disrupted cerebral blood flow networks in idiopathic generalized epilepsy: Arterial spin labeling and graph theoretical analysis. Sone D, Watanabe M, Ota M, Kimura Y, Sugiyama A, Maekawa T, Okura M, Enokizono M, Imabayashi E, Sato N, Matsuda H. Epilepsy Res. 2017;129:95-100. doi: 10.1016/j.eplepsyres.2016.12.009 9. White matter abnormalities in patients with temporal lobe epilepsy and amygdala enlargement: Comparison with hippocampal sclerosis and healthy subjects. Sone D, Ota M, Maikusa N, Kimura Y, Sumida K, Yokoyama K, Imabayashi E, Watanabe M, Watanabe Y, Okazaki M, Sato N, Matsuda H. Epilepsy Res. 2016;127:221-8. doi: 10.1016/j.eplepsyres.2016.09.011 8. Impaired cerebral blood flow networks in temporal lobe epilepsy with hippocampal sclerosis: A graph theoretical approach. Sone D, Matsuda H, Ota M, Maikusa N, Kimura Y, Sumida K, Yokoyama K, Imabayashi E, Watanabe M, Watanabe Y, Okazaki M, Sato N. Epilepsy Behav. 2016;62:239-45. doi: 10.1016/j.yebeh.2016.07.016 7. Automated subfield volumetric analysis of hippocampus in temporal lobe epilepsy using high-resolution T2-weighed MR imaging. Sone D, Sato N, Maikusa N, Ota M, Sumida K, Yokoyama K, Kimura Y, Imabayashi E, Watanabe Y, Watanabe M, Okazaki M, Onuma T, Matsuda H. Neuroimage Clin. 2016;12:57-64. doi: 10.1016/j.nicl.2016.06.008 6. Graph Theoretical Analysis of Structural Neuroimaging in Temporal Lobe Epilepsy with and without Psychosis. Sone D, Matsuda H, Ota M, Maikusa N, Kimura Y, Sumida K, Yokoyama K, Imabayashi E, Watanabe M, Watanabe Y, Okazaki M, Sato N. PLoS One. 2016;11(7):e0158728. doi: 10.1371/journal.pone.0158728 5. Adult-onset refractory epilepsy with hypothalamic hamartoma and no gelastic seizures successfully treated by stereotactic thermocoagulation: A case report. Sone D, Kaido T, Watanabe M, Murata Y, Taniguchi G, Otsuki T. Seizure. 2016;37:32-4. doi: 10.1016/j.seizure.2016.02.013 4. Striatal glucose hypometabolism in preadolescent-onset dentatorubral-pallidoluysian atrophy. Sone D, Sato N, Yokoyama K, Sumida K, Kanai M, Imabayashi E, Saito Y, Matsuda H. J Neurol Sci. 2016;360:121-4. doi: 10.1016/j.jns.2015.12.002 3. Noninvasive evaluation of the correlation between regional cerebral blood flow and intraventricular brain temperature in temporal lobe epilepsy. Sone D, Ota M, Yokoyama K, Sumida K, Kimura Y, Imabayashi E, Matsuda H, Sato N. Magn Reson Imaging. 2016;34(4):451-4. doi: 10.1016/j.mri.2015.12.018 2. Evaluation of amygdala pathology using (11)C-methionine positron emission tomography/computed tomography in patients with temporal lobe epilepsy and amygdala enlargement. Sone D, Ito K, Taniguchi G, Murata Y, Nakata Y, Watanabe Y, Okazaki M, Sato N, Matsuda H, Watanabe M. Epilepsy Res. 2015;112:114-21. doi: 10.1016/j.eplepsyres.2015.02.018 1. A case of autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) coexisting with pervasive developmental disorder harboring SCN1A mutation in addition to CHRNB2 mutation. Sone D, Sugawara T, Sakakibara E, Tomioka Y, Taniguchi G, Murata Y, Watanabe M, Kaneko S. Epilepsy Behav. 2012;25(2):192-5. doi: 10.1016/j.yebeh.2012.07.027 英文原著論文 (Co-Author) 52. Two distinct trajectories of brain volume loss in myotonic dystrophy type 1 via machine learning. Imokawa T, Maki H, Sone D, Kagaya R, Shigemoto Y, Kimura Y, Matsuda H, Takahashi Y, Tateishi U, Sato N. Brain Commun. 2025;7(3):fcaf181. doi: 10.1093/braincomms/fcaf181 51. Brain Hypertrophy in Patients With Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis and Its Clinical Correlates. Zubal R, Velicky Buecheler M, Sone D, Postma T, de Tisi J, Caciagli L, Winston GP, Sidhu MK, Long L, Xiao B, McEvoy AW, Miserocchi A, Vos SB, Baumann C, Duncan JS, Koepp MJ, Galovic M. Neurology. 2025;104(2):e210182. doi:10.1212/WNL.0000000000210182. 50. Integrating psychiatry into basic clinical skills: A three-year nationwide quantitative assessment of postgraduate training programs. Tamune H, Fujikawa H, Harada H, Kodama T, Sasaki M, Sone D, Sekine M, Ito M, Kato T, Nishizaki Y, Tokuda Y. PCN Rep. 2024;3(4):e70014. doi: 10.1002/pcn5.70014. 49. Assessment of Gray Matter Microstructural Alterations in Alzheimer's Disease by Free Water Imaging. Nakaya M, Sato N, Matsuda H, Maikusa N, Ota M, Shigemoto Y, Sone D, Yamao T, Kimura Y, Tsukamoto T, Yokoi Y, Sakata M, Abe O. J Alzheimers Dis. 2024;99(4):1441-1453. doi: 10.3233/JAD-231416. 48. Glymphatic System Activity and Brain Morphology in Patients With Psychogenic Non-epileptic Seizures. Ota M, Sone D, Shigemoto Y, Kimura Y, Matsuda H, Sato N. Cureus. 2024;16(1):e53072. doi:10.7759/cureus.53072. 47. Identification of different MRI atrophy progression trajectories in epilepsy by Subtype and Stage Inference. Xiao F, Caciagli L, Wandschneider B, Sone D, Young AL, Vos SB, Winston GP, Zhang Y, Liu W, An D, Kanber B, Zhou D, Sander JW, Thom M, Duncan JS, Alexander DC, Galovic M, Koepp MJ. Brain. 2023;146(11):4702-4716. doi: 10.1093/brain/awad284. 46. Age and Sex-Related Effects on Single-Subject Gray Matter Networks in Healthy Participants. Shigemoto Y, Sato N, Maikusa N, Sone D, Ota M, Kimura Y, Chiba E, Okita K, Yamao T, Nakaya M, Maki H, Arizono E, Matsuda H. J Pers Med. 2023;13(3):419. doi: 10.3390/jpm13030419 45. Free water derived by multi-shell diffusion MRI reflects tau/neuroinflammatory pathology in Alzheimer’s disease. Nakaya M, Sato N, Matsuda H, Maikusa N, Shigemoto Y, Sone D, Yamao T, Ogawa M, Kimura Y Chiba E, Ohnishi M, Kato K, Okita K, Imabayashi E, Tsukamoto T, Yokoi Y, Sakata M, Abe O. Alzheimers Dement (N Y). 2022;8:e12356. doi: 10.1002/trc2.12356 44. Post-hoc analysis of a cross-sectional nationwide survey assessing psychological distress in electroencephalography technicians during the COVID-19 pandemic in Japan: Qualitative and quantitative text analysis of open-ended response data. Kuroda N, Iwayama T, Kubota T, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Matsubara T, Nagino N, Neshige S, Soga T, Sone D, Takayama Y, Kuramochi I; IMPACT-J EPILEPSY study group. Epilepsy&Seizure. 2022;14(1):58-70. doi: 10.3805/eands.14.58 43. Impact of COVID-19 pandemic on epilepsy care in Japan: A national-level multicenter retrospective cohort study. Kuroda N, Kubota T, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Kuramochi I, Matsubara T, Nagino N, Neshige S, Soga T, Takayama Y, Sone D; IMPACT-J EPILEPSY study group. Epilepsia Open. 2022;7:431-441. doi: 10.1002/epi4.12616 42. Effect of Anti-seizure Medications on Functional Anatomy of Language: A Perspective From Language Functional Magnetic Resonance Imaging. Xiao F, Caciagli L, Wandschneider B, Joshi B, Vos SB, Hill A, Galovic M, Long L, Sone D, Trimmel K, Sander JW, Zhou D, Thompson PJ, Baxendale S, Duncan JS, Koepp MJ. Front Neurosci. 2022;15:787272. doi: 10.3389/fnins.2021.787272 41. Barriers to telemedicine among physicians in epilepsy care during the COVID-19 pandemic: A national-level cross-sectional survey in Japan. Kubota T, Kuroda N, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Kuramochi I, Matsubara T, Nagino N, Neshige S, Soga T, Takayama Y, Sone D. Epilepsy Behav. 2022;126:108487. doi: 10.1016/j.yebeh.2021.108487 40. Risk factors for psychological distress in electroencephalography technicians during the COVID-19 pandemic: A national-level cross-sectional survey in Japan. Kuroda N, Kubota T, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Matsubara T, Nagino N, Neshige S, Soga T, Sone D, Takayama Y, Kuramochi I; IMPACT-J EPILEPSY. Epilepsy Behav. 2021;125:108361. doi: 10.1016/j.yebeh.2021.108361 39. Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis. Shigemoto Y, Sato N, Sone D, Maikusa N, Kimura Y, Chiba E, Suzuki F, Fujii H, Takayama Y, Iwasaki M, Nakagawa E, Matsuda H. Epilepsy Res. 2021;177: 106766. doi: 10.1016/j.eplepsyres.2021.106766 38. Histopathological validation and clinical correlates of hippocampal subfield volumetry based on T2-weighted MRI in temporal lobe epilepsy with hippocampal sclerosis. Mizutani M, Sone D, Sano T, Kimura Y, Maikusa N, Shigemoto Y, Goto Y, Takao M, Iwasaki M, Matsuda H, Sato N, Saito Y. Epilepsy Res. 2021;177:106759. doi: 10.1016/j.eplepsyres.2021.106759 37. Accurate lateralization and classification of MRI-negative 18F-FDG-PET-positive temporal lobe epilepsy using double inversion recovery and machine-learning. Beheshti I, Sone D, Maikusa N, Kimura Y, Shigemoto Y, Sato N, Matsuda H. Comput Biol Med. 2021;137:104805. doi: 10.1016/j.compbiomed.2021.104805 36. Voxel-based correlation of 18F-THK5351 accumulation with gray matter structural networks in cognitively normal older adults. Shigemoto Y, Sone D, Maikusa N, Kimura Y, Suzuki F, Fujii H, Sato N, Matsuda H. eNeurologicalSci. 2021;23:100343. doi: 10.1016/j.ensci.2021.100343 35. Gray matter structural networks related to 18F-THK5351 retention in cognitively normal older adults and Alzheimer's disease patients. Shigemoto Y, Sone D, Okita K, Maikusa N, Yamao T, Kimura Y, Suzuki F, Fujii H, Kato K, Sato N, Matsuda H. eNeurologicalSci. 2021;22:100309. doi: 10.1016/j.ensci.2021.100309 34. FLAIR-wise machine-learning classification and lateralization of MRI-negative 18F-FDG PET-positive temporal lobe epilepsy. Beheshti I, Sone D, Maikusa N, Kimura Y, Shigemoto Y, Sato N, Matsuda H. Front Neurol. 2020;11:580713. doi: 10.3389/fneur.2020.580713 33. Pattern analysis of glucose metabolic brain data for lateralization of MRI-negative temporal lobe epilepsy. Beheshti I, Sone D, Maikusa N, Kimura Y, Shigemoto Y, Sato N, Matsuda H. Epilepsy Res. 2020;167:106474. doi: 10.1016/j.eplepsyres.2020.106474 32. T1-weighted MRI-driven Brain Age Estimation in Alzheimer’s Disease and Parkinson’s Disease. Beheshti I, Mishra S, Sone D, Khanna P, Matsuda H; the Alzheimer's Disease Neuroimaging Initiative, Parkinson’s Progression Markers Initiative Aging Dis. 2020;11(3):618-628. doi: 10.14336/AD.2019.0617 31. Alteration of the anatomical covariance network after corpus callosotomy in pediatric intractable epilepsy. Ueda R, Matsuda H, Sato N, Iwasaki M, Sone D, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Saito T, Komaki H, Nakagawa E, Sugai K, Sasaki M, Kaga Y, Takeichi H, Inagaki M. PLoS One. 2019;14(12):e0222876. doi: 10.1371/journal.pone.022287632. 30. Voxel-based correlation of 18F-THK5351 accumulation and gray matter volume in the brain of cognitively normal older adults. Shigemoto Y, Sone D, Ota M, Maikusa N, Ogawa M, Okita K, Takano H, Kato K, Kimura Y, Morimoto E, Suzuki F, Fujii H, Sato N, Matsuda H. EJNMMI Res. 2019;9(1):81. doi: 10.1186/s13550-019-0552-3 29. Longitudinal analysis of risk factors for dementia based on Mild Cognitive Impairment Screen results and questionnaire responses from healthy Japanese individuals registered in an online database. Ogawa M, Maruo K, Sone D, Shimada H, Suzuki K, Watanabe H, Matsuda H, Mizusawa H. Alzheimers Dement (N Y). 2019;5:347-353. doi: 10.1016/j.trci.2019.06.003 28. Association between subfield volumes of the medial temporal lobe and cognitive assessments. Ogawa M, Sone D, Beheshti I, Maikusa N, Okita K, Takano H, Matsuda H. Heliyon. 2019;5(6):e01828. doi: 10.1016/j.heliyon.2019.e01828 27. Automated Volumetry of Medial Temporal Lobe Subregions in Mild Cognitive Impairment and Alzheimer Disease. Hata K, Nakamoto K, Nunomura A, Sone D, Maikusa N, Ogawa M, Sato N, Matsuda H. Alzheimer Dis Assoc Disord. 2019;33(3):206-211. doi: 10.1097/WAD.0000000000000318 26. Disrupted cortico-ponto-cerebellar pathway in patients with hemimegalencephaly. Enokizono M, Sato N, Ota M, Shigemoto Y, Morimoto E, Oba M, Sone D, Kimura Y, Sugai K, Sasaki M, Ikegaya N, Iwasaki M, Matsuda H. Brain Dev. 2019;41(6):507-515. doi: 10.1016/j.braindev.2019.01.002 25. Association of deposition of tau and amyloid-β proteins with structural connectivity changes in cognitively normal older adults and Alzheimer's disease spectrum patients. Shigemoto Y, Sone D, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Sato N, Matsuda H. Brain Behav. 2018;8(12):e01145. doi: 10.1002/brb3.1145 24. Dissociation of Tau Deposits and Brain Atrophy in Early Alzheimer's Disease: A Combined Positron Emission Tomography/Magnetic Resonance Imaging Study. Shigemoto Y, Sone D, Imabayashi E, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Sato N, Matsuda H. Front Aging Neurosci. 2018;10:223. doi: 10.3389/fnagi.2018.00223 23. Analysis of risk factors for mild cognitive impairment based on word list memory test results and questionnaire responses in healthy Japanese individuals registered in an online database. Ogawa M, Sone D, Maruo K, Shimada H, Suzuki K, Watanabe H, Matsuda H, Mizusawa H. PLoS One. 2018;13(5):e0197466. doi: 10.1371/journal.pone.0197466 22. Gray Matter and White Matter Abnormalities in Temporal Lobe Epilepsy Patients with and without Hippocampal Sclerosis. Beheshti I, Sone D, Farokhian F, Maikusa N, Matsuda H. Front Neurol. 2018;9:107. doi: 10.3389/fneur.2018.00107 21. MR findings in the substantia nigra on phase difference enhanced imaging in neurodegenerative parkinsonism. Sugiyama A, Sato N, Kimura Y, Ota M, Maekawa T, Sone D, Enokizono M, Murata M, Matsuda H, Kuwabara S. Parkinsonism Relat Disord. 2018;48:10-16. doi: 10.1016/j.parkreldis.2017.12.021 20. The use of diffusional kurtosis imaging and neurite orientation dispersion and density imaging of the brain in major depressive disorder. Ota M, Noda T, Sato N, Hidese S, Teraishi T, Setoyama S, Sone D, Matsuda H, Kunugi H. J Psychiatr Res. 2018;98:22-29. doi: 10.1016/j.jpsychires.2017.12.011 19. Comparing CAT12 and VBM8 for Detecting Brain Morphological Abnormalities in Temporal Lobe Epilepsy. Farokhian F, Beheshti I, Sone D, Matsuda H. Front Neurol. 2017;8:428. doi: 10.3389/fneur.2017.00428 18. Brain gray matter structural network in myotonic dystrophy type 1. Sugiyama A, Sone D, Sato N, Kimura Y, Ota M, Maikusa N, Maekawa T, Enokizono M, Mori-Yoshimura M, Ohya Y, Kuwabara S, Matsuda H. PLoS One. 2017;12(11):e0187343. doi: 10.1371/journal.pone.0187343 17. Correlations between dopamine transporter density measured by 123I-FP-CIT SPECT and regional gray matter volume in Parkinson's disease. Maekawa T, Sato N, Ota M, Sugiyama A, Sone D, Enokizono M, Kimura Y, Mukai Y, Murata M, Takano H, Imabayashi E, Matsuda H, Kunimatsu A, Abe O. Jpn J Radiol. 2017;35(12):755-759. doi: 10.1007/s11604-017-0694-z 16. A structural MRI study of cholinergic pathways and cognition in multiple sclerosis. Kimura Y, Sato N, Ota M, Maikusa N, Maekawa T, Sone D, Enokizono M, Sugiyama A, Imabayashi E, Matsuda H, Okamoto T, Yamamura T, Sugimoto H. eNeurologicalSci. 2017;8:11-16. doi: 10.1016/j.ensci.2017.06.008 15. (-)-Linalool influence on the cerebral blood flow in healthy male volunteers revealed by three-dimensional pseudo-continuous arterial spin labeling. Ota M, Sato N, Sone D, Ogura J, Kunugi H. Indian J Psychiatry. 2017;59(2):225-227. doi: 10.4103/psychiatry.IndianJPsychiatry_323_16 14. Whole brain analyses of age-related microstructural changes quantified using different diffusional magnetic resonance imaging methods. Ota M, Sato N, Maikusa N, Sone D, Matsuda H, Kunugi H. Jpn J Radiol. 2017;35(10):584-589. doi: 10.1007/s11604-017-0670-7 13. "Black butterfly" sign on T2*-weighted and susceptibility-weighted imaging: A novel finding of chronic venous congestion of the brain stem and spinal cord associated with dural arteriovenous fistulas. Enokizono M, Sato N, Morikawa M, Kimura Y, Sugiyama A, Maekawa T, Sone D, Takewaki D, Okamoto T, Takahashi Y, Horie N, Matsuo T. J Neurol Sci. 2017;379:64-68. doi: 10.1016/j.jns.2017.05.066 12. Validation of the cingulate island sign with optimized ratios for discriminating dementia with Lewy bodies from Alzheimer's disease using brain perfusion SPECT. Imabayashi E, Soma T, Sone D, Tsukamoto T, Kimura Y, Sato N, Murata M, Matsuda H. Ann Nucl Med. 2017;31(7):536-543. doi: 10.1007/s12149-017-1181-4 11. Thalamic involvement determined by VSRAD advance on MRI and easy Z-score analysis of (99m)Tc-ECD-SPECT in Gerstmann-Sträussler-Scheinker syndrome with P102L mutation. Sugiyama A, Sato N, Kimura Y, Maekawa T, Wakasugi N, Sone D, Enokizono M, Takahashi Y, Murata M, Mizusawa H, Matsuda H. J Neurol Sci. 2017;373:27-30. doi: 10.1016/j.jns.2016.12.021 10. Computed-tomography-guided anatomic standardization for quantitative assessment of dopamine transporter SPECT. Yokoyama K, Imabayashi E, Sumida K, Sone D, Kimura Y, Sato N, Mukai Y, Murata M, Matsuda H. Eur J Nucl Med Mol Imaging. 2017;44(3):366-372. doi: 10.1007/s00259-016-3496-0 9. The cingulate island sign within early Alzheimer's disease-specific hypoperfusion volumes of interest is useful for differentiating Alzheimer's disease from dementia with Lewy bodies. Imabayashi E, Yokoyama K, Tsukamoto T, Sone D, Sumida K, Kimura Y, Sato N, Murata M, Matsuda H. EJNMMI Res. 2016;6(1):67. doi: 10.1186/s13550-016-0224-5 8. Intraventricular temperature measured by diffusion-weighted imaging compared with brain parenchymal temperature measured by MRS in vivo. Sumida K, Sato N, Ota M, Sakai K, Sone D, Yokoyama K, Kimura Y, Maikusa N, Imabayashi E, Matsuda H, Kunimatsu A, Ohtomo K. NMR Biomed. 2016;29(7):890-5. doi: 10.1002/nbm.3542 7. A case of autoimmune epilepsy associated with anti-leucine-rich glioma inactivated subunit 1 antibodies manifesting electrical shock-like sensations and transparent sadness. Murata Y, Watanabe O, Taniguchi G, Sone D, Fujioka M, Okazaki M, Nakagawa E, Watanabe Y, Watanabe M. Epilepsy Behav Case Rep. 2015;4:91-3. doi: 10.1016/j.ebcr.2015.08.004 6. Effect of electroconvulsive therapy on gray matter volume in major depressive disorder. Ota M, Noda T, Sato N, Okazaki M, Ishikawa M, Hattori K, Hori H, Sasayama D, Teraishi T, Sone D, Kunugi H. J Affect Disord. 2015;186:186-91. doi: 10.1016/j.jad.2015.06.051 5. Intraventricular cerebrospinal fluid temperature analysis using MR diffusion-weighted imaging thermometry in Parkinson's disease patients, multiple system atrophy patients, and healthy subjects. Sumida K, Sato N, Ota M, Sakai K, Nippashi Y, Sone D, Yokoyama K, Ito K, Maikusa N, Imabayashi E, Matsuda H, Yamada K, Murata M, Kunimatsu A, Ohtomo K. Brain Behav. 2015;5(6):e00340. doi: 10.1002/brb3.340 4. Nonconvulsive status epilepticus in the elderly associated with newer antidepressants used at therapeutic doses: A report of three cases. Taniguchi G, Miyajima M, Watanabe M, Murata Y, Sone D, Watanabe Y, Okazaki M, Kobayashi-Kimura M, Kato M, Onuma T. Epilepsy Behav Case Rep. 2014;3:8-11. doi: 10.1016/j.ebcr.2014.10.003 3. Chronic periodic lateralised epileptic discharges and anti-N-methyl-D-aspartate receptor antibodies. Sakakibara E, Takahashi Y, Murata Y, Taniguchi G, Sone D, Watanabe M. Epileptic Disord. 2014;16(2):218-22. doi: 10.1684/epd.2014.0655 2. Complex regional pain syndrome in a 15-year-old girl successfully treated with continuous epidural anesthesia. Saito Y, Baba S, Takahashi A, Sone D, Akashi N, Koichihara R, Ishiyama A, Saito T, Komaki H, Nakagawa E, Sugai K, Sasaki M, Otsuki T. Brain Dev. 2015;37(1):175-8. doi: 10.1016/j.braindev.2014.03.002 1. A case of paroxysmal kinesigenic dyskinesia with complex partial seizure probably associated with amygdala enlargement Mogi T, Komori T, Morino M, Taniguchi G, Sone D, Murata Y, Watanabe M, Watanabe Y. Epilepsy&Seizure. 2014;7(1):1-13. doi: 10.3805/eands.7.1 英文総説 10. Seeking the neural basis of neuropsychiatric symptoms in dementia: Neuroimaging findings and controversies. Sone D, Shinagawa S. Front Aging Neurosci. 2025;17:1633309. doi: 10.3389/fnagi.2025.1633309 9. Neuropsychiatry revisited: epilepsy as the borderland between neurology and psychiatry. Sone D, Kanemoto K. Front Psychiatry. 2024;15:1486667. doi: 10.3389/fpsyt.2024.1486667 8. White matter structural connectivity and its impact on psychogenic non-epileptic seizures: an evidence-based review. Sone D. Neuropsychiatr Dis Treat. 2023;19:1573-1579. doi: 10.2147/NDT.S402378 7. Neurobiological Mechanisms of Psychosis in Epilepsy: Findings from Neuroimaging Studies. Sone D. Front Psychiatry. 2022;13:1079295. doi: 10.3389/fpsyt.2022.1079295 6. Neuropsychiatric Aspects of Long COVID: A Comprehensive Review. Kubota T, Kuroda N, Sone D. Psychiatry Clin Neurosci. 2023;77(2):84-93. doi: 10.1111/pcn.13508 5. Neuroimaging-Based Brain Age Estimation: A Promising Personalized Biomarker in Neuropsychiatry. Sone D, Beheshti I. J Pers Med. 2022;12(11):1850. doi: 10.3390/jpm12111850 4. Making the invisible visible: Advanced neuroimaging techniques in focal epilepsy. Sone D. Front Neurosci. 2021;15:699176. doi: 10.3389/fnins.2021.699176 3. Clinical application of machine learning models for brain imaging in epilepsy: A review. Sone D, Beheshti I. Front Neurosci. 2021;15:684825. doi: 10.3389/fnins.2021.684825 2. Nuclear Imaging in Epilepsy: Principles and Progress. Shigemoto Y, Sone D, Kimura Y, Sato N, Matsuda H. Epilepsy&Seizure. 2020;12(1):40-8. doi: 10.3805/eands.12.40 1. Neurite orientation and dispersion density imaging: clinical utility, efficacy, and role in therapy. Sone D. Reports in Medical Imaging. 2019;12:17-29. doi: 10.2147/RMI.S194083

研究テーマ

てんかん、神経画像、認知症、精神神経疾患、核医学

研究業績（論文）

英文原著論文 (First Author)

32. Neuropsychiatric symptoms and neuroimaging-based brain age in mild cognitive impairment and early dementia: A multicenter study.
Sone D, Beheshti I, Tagai K, Kameyama H, Takasaki E, Kashibayashi T, Takahashi R, Ishii K, Kanemoto H, Ikeda M, Shigeta M, Shinagawa S, Kazui H.
Psychiatry Clin Neurosci. 2025;79(4):158-164. doi: 10.1111/pcn.13777

31. Estimated Disease Progression Trajectory of White Matter Disruption in Unilateral Temporal Lobe Epilepsy: A Data-Driven Machine Learning Approach.
Sone D, Sato N, Shigemoto Y, Beheshti I, Kimura Y, Matsuda H.
Brain Sci. 2024;14(10):992. doi: 10.3390/brainsci14100992

30. White matter brain-age in diverse forms of epilepsy and interictal psychosis.
Sone D, Beheshti I, Shigemoto Y, Kimura Y, Sato N, Matsuda H.
Sci Rep. 2024;14(1):19156. doi: 10.1038/s41598-024-70313-w

29. Disease Progression Patterns of Brain Morphology in Schizophrenia: More Progressed Stages in Treatment Resistance.
Sone D, Young A, Shinagawa S, Tsugawa S, Iwata Y, Tarumi R, Ogyu K, Honda S, Ochi R, Matsushita K, Ueno F, Hondo N, Koreki A, Torres-Carmona E, Mar W, Chan N, Koizumi T, Kato H, Kusudo K, de Luca V, Gerretsen P, Remington G, Onaya M, Noda Y, Uchida H, Mimura M, Shigeta M, Graff-Guerrero A, Nakajima S.
Schizophr Bull. 2024;50(2):393-402. doi: 10.1093/schbul/sbad164

28. Contribution of the μ-opioid receptor system to affective disorders in temporal lobe epilepsy: a bidirectional relationship?
Sone D, Galovic M, Myers J, Leonhardt G, Rabiner I, Duncan JS, Koepp MJ, Foong J.
Epilepsia. 2023;64(2):420-429. doi: 10.1111/epi.17463

27. Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis.
Sone D, Sato N, Shigemoto Y, Kimura Y, Matsuda H.
Epilepsia Open. 2022;7(4):657-664. doi: 10.1002/epi4.12645

26. Neuroimaging-derived brain age is associated with life satisfaction in cognitively unimpaired elderly: A community-based study.
Sone D, Beheshti I, Shinagawa S, Niimura H, Kobayashi N, Kida H, Shikimoto R, Noda Y, Nakajima S, Bun S, Mimura M, Shigeta M.
Transl Psychiatry. 2022;12(1):22. doi: 10.1038/s41398-022-01793-5

25. Optimal Surgical Extent for Memory and Seizure Outcome in Temporal Lobe Epilepsy.
Sone D, Ahmad M, Thompson PJ, Baxendale S, Vos SB, Xiao F, de Tisi J, McEvoy AW, Miserocchi A, Duncan JS, Koepp MJ, Galovic M.
Ann Neurol. 2022;91(1):131-144. doi: 10.1002/ana.26266

24. Quantitative analysis of double inversion recovery and FLAIR signals in temporal lobe epilepsy.
Sone D, Sato N, Kimura Y, Maikusa N, Shigemoto Y, Matsuda H.
Epilepsy Res. 2021;170:106540. doi: 10.1016/j.eplepsyres.2020.106540

23. Association between neurite metrics and tau/inflammatory pathology in Alzheimer’s disease.
Sone D, Shigemoto Y, Ogawa M, Maikusa N, Okita K, Takano H, Kato K, Sato N, Matsuda H.
Alzheimers Dement (Amst). 2020;12(1):e12125. doi: 10.1002/dad2.12125

22. Disrupted White Matter Integrity and Structural Brain Networks in Temporal Lobe Epilepsy With and Without Interictal Psychosis.
Sone D, Sato N, Shigemoto Y, Kimura Y, Maikusa N, Ota M, Foong J, Koepp M, Matsuda H.
Front Neurol. 2020;11:556569. doi: 10.3389/fneur.2020.556569

21. Neuroimaging-based brain-age prediction in diverse forms of epilepsy: a signature of psychosis and beyond.
Sone D, Beheshti I, Maikusa N, Ota M, Kimura Y, Sato N, Koepp M, Matsuda H.
Mol Psychiatry. 2021;26(3):825-834. doi: 10.1038/s41380-019-0446-9

20. Widely Impaired White Matter Integrity and Altered Structural Brain Networks in Psychogenic Non-Epileptic Seizures.
Sone D, Sato N, Ota M, Kimura Y, Matsuda H.
Neuropsychiatr Dis Treat. 2019;15:3549-3555. doi: 10.2147/NDT.S235159

19. Similar and Differing Distributions Between 18F-FDG-PET and Arterial Spin Labeling Imaging in Temporal Lobe Epilepsy.
Sone D, Maikusa N, Sato N, Kimura Y, Ota M, Matsuda H.
Front Neurol. 2019;10:318. doi: 10.3389/fneur.2019.00318

18. Reduced resilience of brain gray matter networks in idiopathic generalized epilepsy: A graph-theoretical analysis.
Sone D, Watanabe M, Maikusa N, Sato N, Kimura Y, Enokizono M, Okazaki M, Matsuda H.
PLoS One. 2019;14(2):e0212494. doi: 10.1371/journal.pone.0212494

17. Abnormal neurite density and orientation dispersion in unilateral temporal lobe epilepsy detected by advanced diffusion imaging.
Sone D, Sato N, Ota M, Maikusa N, Kimura Y, Matsuda H.
Neuroimage Clin. 2018;20:772-782. doi: 10.1016/j.nicl.2018.09.017

16. Voxel-based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) on 3-tesla Normal Database: Diagnostic Accuracy in Two Independent Cohorts with Early Alzheimer's Disease.
Sone D, Imabayashi E, Maikusa N, Ogawa M, Sato N, Matsuda H; Japanese-Alzheimer’s Disease Neuroimaging Initiative.
Aging Dis. 2018;9(4):755-760. doi: 10.14336/AD.2017.0818

15. Brain morphological and microstructural features in cryptogenic late-onset temporal lobe epilepsy: a structural and diffusion MRI study.
Sone D, Sato N, Kimura Y, Watanabe Y, Okazaki M, Matsuda H.
Neuroradiology. 2018;60(6):635-641. doi: 10.1007/s00234-018-2019-z

14. Marked accumulation of oligodendroglia-like cells in temporal lobe epilepsy with amygdala enlargement and hippocampal sclerosis.
Sone D, Ikemura M, Saito Y, Taniguchi G, Kunii N.
Neuropathology. 2018;38(2):154-158. doi: 10.1111/neup.12410

13. Subtle abnormality in neurite dispersion in idiopathic generalized epilepsy detected by an advanced diffusion imaging technique.
Sone D, Watanabe M, Ota M, Imabayashi E, Rokicki J, Maikusa N, Sugiyama A, Maekawa T, Enokizono M, Kimura Y, Matsuda H, Sato N.
Epilepsy & Seizure. 2018;10:33-43. doi: 10.3805/eands.10.33

12. Noninvasive detection of focal brain hyperthermia related to continuous epileptic activities using proton MR spectroscopy.
Sone D, Ikegaya N, Takahashi A, Sumida K, Ota M, Saito T, Kimura Y, Matsuda H, Sato N.
Epilepsy Res. 2017;138:1-4. doi: 10.1016/j.eplepsyres.2017.10.001

11. Regional tau deposition and subregion atrophy of medial temporal structures in early Alzheimer's disease: A combined positron emission tomography/magnetic resonance imaging study.
Sone D, Imabayashi E, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Matsuda H.
Alzheimers Dement (Amst). 2017;9:35-40. doi: 10.1016/j.dadm.2017.07.001

10. Thalamic hypoperfusion and disrupted cerebral blood flow networks in idiopathic generalized epilepsy: Arterial spin labeling and graph theoretical analysis.
Sone D, Watanabe M, Ota M, Kimura Y, Sugiyama A, Maekawa T, Okura M, Enokizono M, Imabayashi E, Sato N, Matsuda H.
Epilepsy Res. 2017;129:95-100. doi: 10.1016/j.eplepsyres.2016.12.009

9. White matter abnormalities in patients with temporal lobe epilepsy and amygdala enlargement: Comparison with hippocampal sclerosis and healthy subjects.
Sone D, Ota M, Maikusa N, Kimura Y, Sumida K, Yokoyama K, Imabayashi E, Watanabe M, Watanabe Y, Okazaki M, Sato N, Matsuda H.
Epilepsy Res. 2016;127:221-8. doi: 10.1016/j.eplepsyres.2016.09.011

8. Impaired cerebral blood flow networks in temporal lobe epilepsy with hippocampal sclerosis: A graph theoretical approach.
Sone D, Matsuda H, Ota M, Maikusa N, Kimura Y, Sumida K, Yokoyama K, Imabayashi E, Watanabe M, Watanabe Y, Okazaki M, Sato N.
Epilepsy Behav. 2016;62:239-45. doi: 10.1016/j.yebeh.2016.07.016

7. Automated subfield volumetric analysis of hippocampus in temporal lobe epilepsy using high-resolution T2-weighed MR imaging.
Sone D, Sato N, Maikusa N, Ota M, Sumida K, Yokoyama K, Kimura Y, Imabayashi E, Watanabe Y, Watanabe M, Okazaki M, Onuma T, Matsuda H.
Neuroimage Clin. 2016;12:57-64. doi: 10.1016/j.nicl.2016.06.008

6. Graph Theoretical Analysis of Structural Neuroimaging in Temporal Lobe Epilepsy with and without Psychosis.
Sone D, Matsuda H, Ota M, Maikusa N, Kimura Y, Sumida K, Yokoyama K, Imabayashi E, Watanabe M, Watanabe Y, Okazaki M, Sato N.
PLoS One. 2016;11(7):e0158728. doi: 10.1371/journal.pone.0158728

5. Adult-onset refractory epilepsy with hypothalamic hamartoma and no gelastic seizures successfully treated by stereotactic thermocoagulation: A case report.
Sone D, Kaido T, Watanabe M, Murata Y, Taniguchi G, Otsuki T.
Seizure. 2016;37:32-4. doi: 10.1016/j.seizure.2016.02.013

4. Striatal glucose hypometabolism in preadolescent-onset dentatorubral-pallidoluysian atrophy.
Sone D, Sato N, Yokoyama K, Sumida K, Kanai M, Imabayashi E, Saito Y, Matsuda H.
J Neurol Sci. 2016;360:121-4. doi: 10.1016/j.jns.2015.12.002

3. Noninvasive evaluation of the correlation between regional cerebral blood flow and intraventricular brain temperature in temporal lobe epilepsy.
Sone D, Ota M, Yokoyama K, Sumida K, Kimura Y, Imabayashi E, Matsuda H, Sato N.
Magn Reson Imaging. 2016;34(4):451-4. doi: 10.1016/j.mri.2015.12.018

2. Evaluation of amygdala pathology using (11)C-methionine positron emission tomography/computed tomography in patients with temporal lobe epilepsy and amygdala enlargement.
Sone D, Ito K, Taniguchi G, Murata Y, Nakata Y, Watanabe Y, Okazaki M, Sato N, Matsuda H, Watanabe M.
Epilepsy Res. 2015;112:114-21. doi: 10.1016/j.eplepsyres.2015.02.018

1. A case of autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) coexisting with pervasive developmental disorder harboring SCN1A mutation in addition to CHRNB2 mutation.
Sone D, Sugawara T, Sakakibara E, Tomioka Y, Taniguchi G, Murata Y, Watanabe M, Kaneko S.
Epilepsy Behav. 2012;25(2):192-5. doi: 10.1016/j.yebeh.2012.07.027

英文原著論文 (Co-Author)

52. Two distinct trajectories of brain volume loss in myotonic dystrophy type 1 via machine learning.
Imokawa T, Maki H, Sone D, Kagaya R, Shigemoto Y, Kimura Y, Matsuda H, Takahashi Y, Tateishi U, Sato N.
Brain Commun. 2025;7(3):fcaf181. doi: 10.1093/braincomms/fcaf181

51. Brain Hypertrophy in Patients With Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis and Its Clinical Correlates.
Zubal R, Velicky Buecheler M, Sone D, Postma T, de Tisi J, Caciagli L, Winston GP, Sidhu MK, Long L, Xiao B, McEvoy AW, Miserocchi A, Vos SB, Baumann C, Duncan JS, Koepp MJ, Galovic M.
Neurology. 2025;104(2):e210182. doi:10.1212/WNL.0000000000210182.

50. Integrating psychiatry into basic clinical skills: A three-year nationwide quantitative assessment of postgraduate training programs.
Tamune H, Fujikawa H, Harada H, Kodama T, Sasaki M, Sone D, Sekine M, Ito M, Kato T, Nishizaki Y, Tokuda Y.
PCN Rep. 2024;3(4):e70014. doi: 10.1002/pcn5.70014.

49. Assessment of Gray Matter Microstructural Alterations in Alzheimer's Disease by Free Water Imaging.
Nakaya M, Sato N, Matsuda H, Maikusa N, Ota M, Shigemoto Y, Sone D, Yamao T, Kimura Y, Tsukamoto T, Yokoi Y, Sakata M, Abe O.
J Alzheimers Dis. 2024;99(4):1441-1453. doi: 10.3233/JAD-231416.

48. Glymphatic System Activity and Brain Morphology in Patients With Psychogenic Non-epileptic Seizures.
Ota M, Sone D, Shigemoto Y, Kimura Y, Matsuda H, Sato N.
Cureus. 2024;16(1):e53072. doi:10.7759/cureus.53072.

47. Identification of different MRI atrophy progression trajectories in epilepsy by Subtype and Stage Inference.
Xiao F, Caciagli L, Wandschneider B, Sone D, Young AL, Vos SB, Winston GP, Zhang Y, Liu W, An D, Kanber B, Zhou D, Sander JW, Thom M, Duncan JS, Alexander DC, Galovic M, Koepp MJ.
Brain. 2023;146(11):4702-4716. doi: 10.1093/brain/awad284.

46. Age and Sex-Related Effects on Single-Subject Gray Matter Networks in Healthy Participants.
Shigemoto Y, Sato N, Maikusa N, Sone D, Ota M, Kimura Y, Chiba E, Okita K, Yamao T, Nakaya M, Maki H, Arizono E, Matsuda H.
J Pers Med. 2023;13(3):419. doi: 10.3390/jpm13030419

45. Free water derived by multi-shell diffusion MRI reflects tau/neuroinflammatory pathology in Alzheimer’s disease.
Nakaya M, Sato N, Matsuda H, Maikusa N, Shigemoto Y, Sone D, Yamao T, Ogawa M, Kimura Y Chiba E, Ohnishi M, Kato K, Okita K, Imabayashi E, Tsukamoto T, Yokoi Y, Sakata M, Abe O.
Alzheimers Dement (N Y). 2022;8:e12356. doi: 10.1002/trc2.12356

44. Post-hoc analysis of a cross-sectional nationwide survey assessing psychological distress in electroencephalography technicians during the COVID-19 pandemic in Japan: Qualitative and quantitative text analysis of open-ended response data.
Kuroda N, Iwayama T, Kubota T, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Matsubara T, Nagino N, Neshige S, Soga T, Sone D, Takayama Y, Kuramochi I; IMPACT-J EPILEPSY study group.
Epilepsy&Seizure. 2022;14(1):58-70. doi: 10.3805/eands.14.58

43. Impact of COVID-19 pandemic on epilepsy care in Japan: A national-level multicenter retrospective cohort study.
Kuroda N, Kubota T, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Kuramochi I, Matsubara T, Nagino N, Neshige S, Soga T, Takayama Y, Sone D; IMPACT-J EPILEPSY study group.
Epilepsia Open. 2022;7:431-441. doi: 10.1002/epi4.12616

42. Effect of Anti-seizure Medications on Functional Anatomy of Language: A Perspective From Language Functional Magnetic Resonance Imaging.
Xiao F, Caciagli L, Wandschneider B, Joshi B, Vos SB, Hill A, Galovic M, Long L, Sone D, Trimmel K, Sander JW, Zhou D, Thompson PJ, Baxendale S, Duncan JS, Koepp MJ.
Front Neurosci. 2022;15:787272. doi: 10.3389/fnins.2021.787272

41. Barriers to telemedicine among physicians in epilepsy care during the COVID-19 pandemic: A national-level cross-sectional survey in Japan.
Kubota T, Kuroda N, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Kuramochi I, Matsubara T, Nagino N, Neshige S, Soga T, Takayama Y, Sone D.
Epilepsy Behav. 2022;126:108487. doi: 10.1016/j.yebeh.2021.108487

40. Risk factors for psychological distress in electroencephalography technicians during the COVID-19 pandemic: A national-level cross-sectional survey in Japan.
Kuroda N, Kubota T, Horinouchi T, Ikegaya N, Kitazawa Y, Kodama S, Matsubara T, Nagino N, Neshige S, Soga T, Sone D, Takayama Y, Kuramochi I; IMPACT-J EPILEPSY.
Epilepsy Behav. 2021;125:108361. doi: 10.1016/j.yebeh.2021.108361

39. Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis.
Shigemoto Y, Sato N, Sone D, Maikusa N, Kimura Y, Chiba E, Suzuki F, Fujii H, Takayama Y, Iwasaki M, Nakagawa E, Matsuda H.
Epilepsy Res. 2021;177: 106766. doi: 10.1016/j.eplepsyres.2021.106766

38. Histopathological validation and clinical correlates of hippocampal subfield volumetry based on T2-weighted MRI in temporal lobe epilepsy with hippocampal sclerosis.
Mizutani M, Sone D, Sano T, Kimura Y, Maikusa N, Shigemoto Y, Goto Y, Takao M, Iwasaki M, Matsuda H, Sato N, Saito Y.
Epilepsy Res. 2021;177:106759. doi: 10.1016/j.eplepsyres.2021.106759

37. Accurate lateralization and classification of MRI-negative 18F-FDG-PET-positive temporal lobe epilepsy using double inversion recovery and machine-learning.
Beheshti I, Sone D, Maikusa N, Kimura Y, Shigemoto Y, Sato N, Matsuda H.
Comput Biol Med. 2021;137:104805. doi: 10.1016/j.compbiomed.2021.104805

36. Voxel-based correlation of 18F-THK5351 accumulation with gray matter structural networks in cognitively normal older adults.
Shigemoto Y, Sone D, Maikusa N, Kimura Y, Suzuki F, Fujii H, Sato N, Matsuda H.
eNeurologicalSci. 2021;23:100343. doi: 10.1016/j.ensci.2021.100343

35. Gray matter structural networks related to 18F-THK5351 retention in cognitively normal older adults and Alzheimer's disease patients.
Shigemoto Y, Sone D, Okita K, Maikusa N, Yamao T, Kimura Y, Suzuki F, Fujii H, Kato K, Sato N, Matsuda H.
eNeurologicalSci. 2021;22:100309. doi: 10.1016/j.ensci.2021.100309

34. FLAIR-wise machine-learning classification and lateralization of MRI-negative 18F-FDG PET-positive temporal lobe epilepsy.
Beheshti I, Sone D, Maikusa N, Kimura Y, Shigemoto Y, Sato N, Matsuda H.
Front Neurol. 2020;11:580713. doi: 10.3389/fneur.2020.580713

33. Pattern analysis of glucose metabolic brain data for lateralization of MRI-negative temporal lobe epilepsy.
Beheshti I, Sone D, Maikusa N, Kimura Y, Shigemoto Y, Sato N, Matsuda H.
Epilepsy Res. 2020;167:106474. doi: 10.1016/j.eplepsyres.2020.106474

32. T1-weighted MRI-driven Brain Age Estimation in Alzheimer’s Disease and Parkinson’s Disease.
Beheshti I, Mishra S, Sone D, Khanna P, Matsuda H; the Alzheimer's Disease Neuroimaging Initiative, Parkinson’s Progression Markers Initiative
Aging Dis. 2020;11(3):618-628. doi: 10.14336/AD.2019.0617

31. Alteration of the anatomical covariance network after corpus callosotomy in pediatric intractable epilepsy.
Ueda R, Matsuda H, Sato N, Iwasaki M, Sone D, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Saito T, Komaki H, Nakagawa E, Sugai K, Sasaki M, Kaga Y, Takeichi H, Inagaki M.
PLoS One. 2019;14(12):e0222876. doi: 10.1371/journal.pone.022287632.

30. Voxel-based correlation of 18F-THK5351 accumulation and gray matter volume in the brain of cognitively normal older adults.
Shigemoto Y, Sone D, Ota M, Maikusa N, Ogawa M, Okita K, Takano H, Kato K, Kimura Y, Morimoto E, Suzuki F, Fujii H, Sato N, Matsuda H.
EJNMMI Res. 2019;9(1):81. doi: 10.1186/s13550-019-0552-3

29. Longitudinal analysis of risk factors for dementia based on Mild Cognitive Impairment Screen results and questionnaire responses from healthy Japanese individuals registered in an online database.
Ogawa M, Maruo K, Sone D, Shimada H, Suzuki K, Watanabe H, Matsuda H, Mizusawa H.
Alzheimers Dement (N Y). 2019;5:347-353. doi: 10.1016/j.trci.2019.06.003

28. Association between subfield volumes of the medial temporal lobe and cognitive assessments.
Ogawa M, Sone D, Beheshti I, Maikusa N, Okita K, Takano H, Matsuda H.
Heliyon. 2019;5(6):e01828. doi: 10.1016/j.heliyon.2019.e01828

27. Automated Volumetry of Medial Temporal Lobe Subregions in Mild Cognitive Impairment and Alzheimer Disease.
Hata K, Nakamoto K, Nunomura A, Sone D, Maikusa N, Ogawa M, Sato N, Matsuda H.
Alzheimer Dis Assoc Disord. 2019;33(3):206-211. doi: 10.1097/WAD.0000000000000318

26. Disrupted cortico-ponto-cerebellar pathway in patients with hemimegalencephaly.
Enokizono M, Sato N, Ota M, Shigemoto Y, Morimoto E, Oba M, Sone D, Kimura Y, Sugai K, Sasaki M, Ikegaya N, Iwasaki M, Matsuda H.
Brain Dev. 2019;41(6):507-515. doi: 10.1016/j.braindev.2019.01.002

25. Association of deposition of tau and amyloid-β proteins with structural connectivity changes in cognitively normal older adults and Alzheimer's disease spectrum patients.
Shigemoto Y, Sone D, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Sato N, Matsuda H.
Brain Behav. 2018;8(12):e01145. doi: 10.1002/brb3.1145

24. Dissociation of Tau Deposits and Brain Atrophy in Early Alzheimer's Disease: A Combined Positron Emission Tomography/Magnetic Resonance Imaging Study.
Shigemoto Y, Sone D, Imabayashi E, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Sato N, Matsuda H.
Front Aging Neurosci. 2018;10:223. doi: 10.3389/fnagi.2018.00223

23. Analysis of risk factors for mild cognitive impairment based on word list memory test results and questionnaire responses in healthy Japanese individuals registered in an online database.
Ogawa M, Sone D, Maruo K, Shimada H, Suzuki K, Watanabe H, Matsuda H, Mizusawa H.
PLoS One. 2018;13(5):e0197466. doi: 10.1371/journal.pone.0197466

22. Gray Matter and White Matter Abnormalities in Temporal Lobe Epilepsy Patients with and without Hippocampal Sclerosis.
Beheshti I, Sone D, Farokhian F, Maikusa N, Matsuda H.
Front Neurol. 2018;9:107. doi: 10.3389/fneur.2018.00107

21. MR findings in the substantia nigra on phase difference enhanced imaging in neurodegenerative parkinsonism.
Sugiyama A, Sato N, Kimura Y, Ota M, Maekawa T, Sone D, Enokizono M, Murata M, Matsuda H, Kuwabara S.
Parkinsonism Relat Disord. 2018;48:10-16. doi: 10.1016/j.parkreldis.2017.12.021

20. The use of diffusional kurtosis imaging and neurite orientation dispersion and density imaging of the brain in major depressive disorder.
Ota M, Noda T, Sato N, Hidese S, Teraishi T, Setoyama S, Sone D, Matsuda H, Kunugi H.
J Psychiatr Res. 2018;98:22-29. doi: 10.1016/j.jpsychires.2017.12.011

19. Comparing CAT12 and VBM8 for Detecting Brain Morphological Abnormalities in Temporal Lobe Epilepsy.
Farokhian F, Beheshti I, Sone D, Matsuda H.
Front Neurol. 2017;8:428. doi: 10.3389/fneur.2017.00428

18. Brain gray matter structural network in myotonic dystrophy type 1.
Sugiyama A, Sone D, Sato N, Kimura Y, Ota M, Maikusa N, Maekawa T, Enokizono M, Mori-Yoshimura M, Ohya Y, Kuwabara S, Matsuda H.
PLoS One. 2017;12(11):e0187343. doi: 10.1371/journal.pone.0187343

17. Correlations between dopamine transporter density measured by 123I-FP-CIT SPECT and regional gray matter volume in Parkinson's disease.
Maekawa T, Sato N, Ota M, Sugiyama A, Sone D, Enokizono M, Kimura Y, Mukai Y, Murata M, Takano H, Imabayashi E, Matsuda H, Kunimatsu A, Abe O.
Jpn J Radiol. 2017;35(12):755-759. doi: 10.1007/s11604-017-0694-z

16. A structural MRI study of cholinergic pathways and cognition in multiple sclerosis.
Kimura Y, Sato N, Ota M, Maikusa N, Maekawa T, Sone D, Enokizono M, Sugiyama A, Imabayashi E, Matsuda H, Okamoto T, Yamamura T, Sugimoto H.
eNeurologicalSci. 2017;8:11-16. doi: 10.1016/j.ensci.2017.06.008

15. (-)-Linalool influence on the cerebral blood flow in healthy male volunteers revealed by three-dimensional pseudo-continuous arterial spin labeling.
Ota M, Sato N, Sone D, Ogura J, Kunugi H.
Indian J Psychiatry. 2017;59(2):225-227. doi: 10.4103/psychiatry.IndianJPsychiatry_323_16

14. Whole brain analyses of age-related microstructural changes quantified using different diffusional magnetic resonance imaging methods.
Ota M, Sato N, Maikusa N, Sone D, Matsuda H, Kunugi H.
Jpn J Radiol. 2017;35(10):584-589. doi: 10.1007/s11604-017-0670-7

13. "Black butterfly" sign on T2*-weighted and susceptibility-weighted imaging: A novel finding of chronic venous congestion of the brain stem and spinal cord associated with dural arteriovenous fistulas.
Enokizono M, Sato N, Morikawa M, Kimura Y, Sugiyama A, Maekawa T, Sone D, Takewaki D, Okamoto T, Takahashi Y, Horie N, Matsuo T.
J Neurol Sci. 2017;379:64-68. doi: 10.1016/j.jns.2017.05.066

12. Validation of the cingulate island sign with optimized ratios for discriminating dementia with Lewy bodies from Alzheimer's disease using brain perfusion SPECT.
Imabayashi E, Soma T, Sone D, Tsukamoto T, Kimura Y, Sato N, Murata M, Matsuda H.
Ann Nucl Med. 2017;31(7):536-543. doi: 10.1007/s12149-017-1181-4

11. Thalamic involvement determined by VSRAD advance on MRI and easy Z-score analysis of (99m)Tc-ECD-SPECT in Gerstmann-Sträussler-Scheinker syndrome with P102L mutation.
Sugiyama A, Sato N, Kimura Y, Maekawa T, Wakasugi N, Sone D, Enokizono M, Takahashi Y, Murata M, Mizusawa H, Matsuda H.
J Neurol Sci. 2017;373:27-30. doi: 10.1016/j.jns.2016.12.021

10. Computed-tomography-guided anatomic standardization for quantitative assessment of dopamine transporter SPECT.
Yokoyama K, Imabayashi E, Sumida K, Sone D, Kimura Y, Sato N, Mukai Y, Murata M, Matsuda H.
Eur J Nucl Med Mol Imaging. 2017;44(3):366-372. doi: 10.1007/s00259-016-3496-0

9. The cingulate island sign within early Alzheimer's disease-specific hypoperfusion volumes of interest is useful for differentiating Alzheimer's disease from dementia with Lewy bodies.
Imabayashi E, Yokoyama K, Tsukamoto T, Sone D, Sumida K, Kimura Y, Sato N, Murata M, Matsuda H.
EJNMMI Res. 2016;6(1):67. doi: 10.1186/s13550-016-0224-5

8. Intraventricular temperature measured by diffusion-weighted imaging compared with brain parenchymal temperature measured by MRS in vivo.
Sumida K, Sato N, Ota M, Sakai K, Sone D, Yokoyama K, Kimura Y, Maikusa N, Imabayashi E, Matsuda H, Kunimatsu A, Ohtomo K.
NMR Biomed. 2016;29(7):890-5. doi: 10.1002/nbm.3542

7. A case of autoimmune epilepsy associated with anti-leucine-rich glioma inactivated subunit 1 antibodies manifesting electrical shock-like sensations and transparent sadness.
Murata Y, Watanabe O, Taniguchi G, Sone D, Fujioka M, Okazaki M, Nakagawa E, Watanabe Y, Watanabe M.
Epilepsy Behav Case Rep. 2015;4:91-3. doi: 10.1016/j.ebcr.2015.08.004

6. Effect of electroconvulsive therapy on gray matter volume in major depressive disorder.
Ota M, Noda T, Sato N, Okazaki M, Ishikawa M, Hattori K, Hori H, Sasayama D, Teraishi T, Sone D, Kunugi H.
J Affect Disord. 2015;186:186-91. doi: 10.1016/j.jad.2015.06.051

5. Intraventricular cerebrospinal fluid temperature analysis using MR diffusion-weighted imaging thermometry in Parkinson's disease patients, multiple system atrophy patients, and healthy subjects.
Sumida K, Sato N, Ota M, Sakai K, Nippashi Y, Sone D, Yokoyama K, Ito K, Maikusa N, Imabayashi E, Matsuda H, Yamada K, Murata M, Kunimatsu A, Ohtomo K.
Brain Behav. 2015;5(6):e00340. doi: 10.1002/brb3.340

4. Nonconvulsive status epilepticus in the elderly associated with newer antidepressants used at therapeutic doses: A report of three cases.
Taniguchi G, Miyajima M, Watanabe M, Murata Y, Sone D, Watanabe Y, Okazaki M, Kobayashi-Kimura M, Kato M, Onuma T.
Epilepsy Behav Case Rep. 2014;3:8-11. doi: 10.1016/j.ebcr.2014.10.003

3. Chronic periodic lateralised epileptic discharges and anti-N-methyl-D-aspartate receptor antibodies.
Sakakibara E, Takahashi Y, Murata Y, Taniguchi G, Sone D, Watanabe M.
Epileptic Disord. 2014;16(2):218-22. doi: 10.1684/epd.2014.0655

2. Complex regional pain syndrome in a 15-year-old girl successfully treated with continuous epidural anesthesia.
Saito Y, Baba S, Takahashi A, Sone D, Akashi N, Koichihara R, Ishiyama A, Saito T, Komaki H, Nakagawa E, Sugai K, Sasaki M, Otsuki T.
Brain Dev. 2015;37(1):175-8. doi: 10.1016/j.braindev.2014.03.002

1. A case of paroxysmal kinesigenic dyskinesia with complex partial seizure probably associated with amygdala enlargement
Mogi T, Komori T, Morino M, Taniguchi G, Sone D, Murata Y, Watanabe M, Watanabe Y.
Epilepsy&Seizure. 2014;7(1):1-13. doi: 10.3805/eands.7.1

英文総説

10. Seeking the neural basis of neuropsychiatric symptoms in dementia: Neuroimaging findings and controversies.
Sone D, Shinagawa S.
Front Aging Neurosci. 2025;17:1633309. doi: 10.3389/fnagi.2025.1633309

9. Neuropsychiatry revisited: epilepsy as the borderland between neurology and psychiatry.
Sone D, Kanemoto K.
Front Psychiatry. 2024;15:1486667. doi: 10.3389/fpsyt.2024.1486667

8. White matter structural connectivity and its impact on psychogenic non-epileptic seizures: an evidence-based review.
Sone D.
Neuropsychiatr Dis Treat. 2023;19:1573-1579. doi: 10.2147/NDT.S402378

7. Neurobiological Mechanisms of Psychosis in Epilepsy: Findings from Neuroimaging Studies.
Sone D.
Front Psychiatry. 2022;13:1079295. doi: 10.3389/fpsyt.2022.1079295

6. Neuropsychiatric Aspects of Long COVID: A Comprehensive Review.
Kubota T, Kuroda N, Sone D.
Psychiatry Clin Neurosci. 2023;77(2):84-93. doi: 10.1111/pcn.13508

5. Neuroimaging-Based Brain Age Estimation: A Promising Personalized Biomarker in Neuropsychiatry.
Sone D, Beheshti I.
J Pers Med. 2022;12(11):1850. doi: 10.3390/jpm12111850

4. Making the invisible visible: Advanced neuroimaging techniques in focal epilepsy.
Sone D.
Front Neurosci. 2021;15:699176. doi: 10.3389/fnins.2021.699176

3. Clinical application of machine learning models for brain imaging in epilepsy: A review.
Sone D, Beheshti I.
Front Neurosci. 2021;15:684825. doi: 10.3389/fnins.2021.684825

2. Nuclear Imaging in Epilepsy: Principles and Progress.
Shigemoto Y, Sone D, Kimura Y, Sato N, Matsuda H.
Epilepsy&Seizure. 2020;12(1):40-8. doi: 10.3805/eands.12.40

1. Neurite orientation and dispersion density imaging: clinical utility, efficacy, and role in therapy.
Sone D.
Reports in Medical Imaging. 2019;12:17-29. doi: 10.2147/RMI.S194083

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曾根 大地（ソネ ダイチ）

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