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研究業績詳細

相川忠夫（アイカワタダオ）

研究テーマ	心血管病における最先端画像診断装置を用いた非侵襲的定量評価法の開発と臨床応用
研究業績（論文）	英文業績 (Corresponding author) Original articles: 1. Saitou T, Manabe O, Nagase A, Toyama H, Kudo T, Oyama-Manabe N, Aikawa T (Corresponding author). Impact of region of interest size on semiquantitative evaluation of myocardial 99mTc-pyrophosphate uptake in suspected transthyretin cardiac amyloidosis. Ann Nucl Cardiol. 2025;11(1):33-38. 2. Kiyohara Y, Aikawa T, Saito T, Casso Dominguez A, Wiley J, Kolte D, Secemsky EA, Yeh RW, Laham RJ, Latib A, Bhatt DL, Kuno T. Comparison of limus and paclitaxel drug-coated balloons, second-generation or newer drug-eluting stents, and balloon angioplasty: a network meta-analysis of randomized controlled trials. Circ Cardiovasc Interv. 2025 Oct 27:e016005. 3. Asanuma T, Hiruma Y, Watanabe A, Shimoda TM, Iwagami M, Hosseini K, Slipczuk L, Wiley J, Briasoulis A, Takagi H, Aikawa T, Kuno T. Efficacy and safety of direct oral anticoagulants versus vitamin K antagonist in patients with left ventricular thrombus: A meta-analysis of randomized controlled trials. J Cardiol. 2025 Dec;86(6):618-621. 4. Aikawa T (Corresponding author), Mori Y, Kohsaka S, Matsue Y, Kuno T, Yamaji K, Ozaki D, Tokano T, Kozuma K, Minamino T. Application and outcomes of coronary atherectomy in acute coronary syndrome: a report from the J-PCI Registry. J Soc Cardiovasc Angiogr Interv. 2025;4(7):103622. 5. Tanimoto K, Kawamura Y, Kimura S, Hasuike Y, Tachibana E, Kudo A, Aikawa T, Murakami K, Fujimoto S. SPECT reconstruction using preprocessing masking for extra-cardiac uptake versus standard processing in 99mTc-sestamibi myocardial perfusion imaging. Ann Nucl Med. 2025 Aug 26. doi: 10.1007/s12149-025-02085-w. 6. Watanabe A, Aikawa T, Miyamoto Y, Ueyama HA, Fujisaki T, Shoji S, Hosseini K, Slipczuk L, Briasoulis A, Kampaktsis PN, Wiley J, Secemsky EA, Iwagami M, Tsugawa Y, Kuno T. Ticagrelor paradox: systematic review and network meta-analysis. J Am Heart Assoc. 2025 Sep 2;14(17):e041959. 7. Ajima T, Aikawa T,** (Corresponding author, Co-first authors), Saitou T, Matsue Y, Fujimoto S, Omote K, Minamino T. Prognostic value of 99mTc-pyrophosphate uptake in patients with suspected transthyretin cardiac amyloidosis. J Nucl Cardiol. 2025 Aug 5:102452. doi: 10.1016/j.nuclcard.2025.102452. 8. Saito T, Miyamoto Y, Fujisaki T, Ueyama H, Watanabe A, Hosseini K, Briasoulis A, Slipczuk L, Takagi H, Shoji S, Iwagami M, Kolte D, Aikawa T, Lavie CJ, Kuno T. Sex Differences in Safety and Efficacy of Dual Antiplatelet Therapy Strategies for Patients With Acute Coronary Syndromes: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Am J Cardiol. 2025 Jul 20;256:81-88. 9. Hashimoto K, Fujisaki T, Aikawa T, Iwagami M, Miyamoto Y, Slipczuk L, Biase LD, Briasoulis A, Yasuhara J, Takagi H, Kuno T. Optimal Thromboembolism Prevention for Patients With Atrial Fibrillation on Long-Term Dialysis. Pacing Clin Electrophysiol. 2025 Jul;48(7):733-753. 10. Tomizawa N, Fan R, Fujimoto S, Nozaki YO, Kawaguchi YO, Takamura K, Hiki M, Aikawa T, Takahashi N, Okai I, Okazaki S, Kumamaru KK, Minamino T, Aoki S. High-resolution deep learning reconstruction to improve the accuracy of CT fractional flow reserve. Eur Radiol. 2025 May 22. doi: 10.1007/s00330-025-11707-w. 11. Tomizawa N, Ozu H, Kamio S, Fujimoto S, Nozaki YO, Fan R, Kawaguchi YO, Takamura K, Hiki M, Aikawa T, Kadowaki S, Ikeda F, Kumamaru KK, Watada H, Minamino T, Aoki S. Effect of sampling rate during dynamic myocardial CT perfusion on coronary flow reserve and ischemia analysis. Int J Cardiovasc Imaging. 2025;41(4):743-753. 12. Kani R, Miyamoto Y, Saito T, Watanabe A, Matsubara K, Ejiri K, Iwagami M, Slipczuk L, Hosseini K, Fujisaki T, Takagi H, Yaku H, Aikawa T, Kuno T. Racial and regional differences in efficacy of sodium-glucose cotransporter 2 inhibitors on cardiorenal outcomes: A systematic review and meta-analysis. Int J Cardiol. 2025;426:133079. 13. Saito T, Watanabe A, Aikawa T, Kapur NK, Kuno T. Comparison of temporary mechanical circulatory support devices for patients with cardiogenic shock after acute myocardial infarction: A network meta-analysis of randomized controlled trials. Int J Cardiol. 2025;423:132997. 14. Mavropoulos SA, Aikawa T, Mazurek R, Sakata T, Yamada K, Watanabe K, Sunagawa G, Veera S, Singleton DT, Leonard K, Kariya T, Sahoo S, Ishikawa K. A minimally invasive swine model of chronic kidney disease-associated heart failure. Am J Physiol Heart Circ Physiol. 2025;328(2):H260-H270. 15. Saitou T*, Aikawa T,** (Corresponding author, Co-first authors), Manabe O, Fujimoto S, Matsue Y, Nagase A, Toyama H, Kudo T, Oyama-Manabe N, Minamino T. Lateral planar imaging of 99mTc-pyrophosphate scintigraphy in patients with suspected transthyretin cardiac amyloidosis. Ann Nucl Cardiol. 2024;10(1):29-37. (IF=-, CI=0) 16. Saito T, Kuno T, Aikawa T, Ueyama HA, Kampaktsis PN, Kolte D, Misumida N, Takagi H, Ahmad Y, Kaneko T, Zajarias A, Latib A. Long-term outcomes with medical therapy, transcatheter repair, or surgery for isolated tricuspid regurgitation: a systematic review and network meta-analysis. Clin Res Cardiol. 2025;114(2):272-280. 17. Odagiri F, Tokano T, Miyazaki T, Hirabayashi K, Ishi K, Abe H, Ishiwata S, Kakihara M, Maki M, Matsumoto H, Shimai R, Aikawa T, Takano S, Kimura Y, Kuroda S, Isogai H, Ozaki D, Shiozawa T, Yasuda Y, Takasu K, Iijima K, Takamura K, Matsubara T, Tabuchi H, Hayashi H, Yokoyama K, Sekita G, Sumiyoshi M, Nakazato Y, Minamino T. Clinical impact of cryoballoon posterior wall isolation using the cross-over technique in persistent atrial fibrillation. Pacing Clin Electrophysiol. 2024;47(10):1326-1337. 18. Xu Y, Korayem A, Cruz-Solbes AS, Chandel N, Sakata T, Mazurek R, Mavropoulos SA, Kariya T, Aikawa T, Yamada KP, D'Escamard V, V'Gangula B, Baker AH, Ma L, Björkegren JLM, Fuster V, Boehm M, Fish KM, Tadros R, Ishikawa K, Kovacic JC. Inhibition of endothelial-to-mesenchymal transition in a large animal preclinical arteriovenous fistula model leads to improved remodelling and reduced stenosis. Cardiovasc Res. 2024;120(14):1768-1779. 19. Kani R, Watanabe A, Miyamoto Y, Ejiri K, Iwagami M, Takagi H, Slipczuk L, Tsugawa Y, Aikawa T, Kuno T. Comparison of effectiveness among different sodium-glucose cotransoporter-2 inhibitors according to underlying conditions: a network meta-analysis of randomized controlled trials. J Am Heart Assoc. 2024;13(3):e031805. (IF=5.0, CI=3) 20. Saito T, Kuno T, Ueyama HA, Kampaktsis PN, Kolte D, Misumida N, Takagi H, Aikawa T, Latib A. Transcatheter edge-to-edge mitral valve repair for mitral regurgitation in patients with cardiogenic shock: A systematic review and meta-analysis. Catheter Cardiovasc Interv. 2023. doi: 10.1002/ccd.30944. (IF=2.1, CI=2) 21. Kuno T, Yamaji K, Aikawa T, Sawano M, Ando T, Numasawa Y, Wada H, Amano T, Kozuma K, Kohsaka S. Transradial intervention in dialysis patients undergoing percutaneous coronary intervention: a Japanese nationwide registry study. Eur Heart J Open. 2023;3(6):oead116. (IF=-, CI=0) 22. Abe H, Miyazaki T, Tomaru M, Nobushima Y, Ajima T, Hirabayashi K, Ishiwata S, Kakihara M, Maki M, Shimai R, Aikawa T, Isogai H, Ozaki D, Yasuda Y, Odagiri F, Takamura K, Hiki M, Iwata H, Yokoyama K, Tokano T, Minamino T. Poor nutritional status during recovery from acute myocardial infarction in patients without an early nutritional intervention predicts a poor prognosis: a single-center retrospective study. Nutrients. 2023;15(22):4748. (IF=4.8, CI=0) 23. Kiyohara Y, Aikawa T* (*Co-first authors), Kayanuma K, Takagi H, Kampaktsis PN, Wiley J, Kuno T. Comparison of clinical outcomes among various percutaneous coronary intervention strategies for small coronary artery disease. Am J Cardiol. 2024;211:334-342. (IF=2.3, CI=2) 24. Aikawa T, Kuno T, Malik AH, Briasoulis A, Kolte D, Kampaktsis PN, Latib A. Transcatheter aortic valve replacement in patients with or without active cancer. J Am Heart Assoc. 2023;12(21):e030072. (IF=5.0, CI=0) 25. Ishisaka Y, Watanabe A, Aikawa T, Kanaoka K, Takagi H, Wiley J, Yasuhara J, Kuno T. Overview of SARS-CoV-2 infection and vaccine associated myocarditis compared to non-COVID-19-associated myocarditis: A systematic review and meta-analysis. Int J Cardiol. 2024;395:131401. (IF=3.2, CI=5) 26. Tsukagoshi J, Shimoda T, Yokoyama Y, Secemsky EA, Shirasu T, Nakama T, Jujo K, Wiley J, Takagi H, Aikawa T, Kuno T. The mid-term effect of intravascular ultrasound on endovascular interventions for lower extremity peripheral arterial disease: a systematic review and meta-analysis. J Vasc Surg. 2023:S0741-5214(23)01942-0. (IF=3.9, CI=2) 27. Hamada S, Ueyama H, Aikawa T, Kampaktsis PN, Misumida N, Takagi H, Kuno T, Latib A. Outcomes of transcatheter edge-to-edge repair for atrial functional mitral regurgitation: A meta-analysis of observational studies. Catheter Cardiovasc Interv. 2023;102(4):751-760. (IF=2.1, CI=1) 28. Ishisaka Y, Aikawa T, Malik A, Kampaktsis PN, Briasoulis A, Kuno T. Association of Remdesivir use with bradycardia: A systematic review and meta-analysis. J Med Virol. 2023;95(8):e29018. (IF=6.8, CI=4) 29. Watanabe A, Malik A, Aikawa T, Briasoulis A, Kuno T. Extracorporeal membrane oxygenation for COVID-19-associated acute respiratory distress syndrome: A nationwide analysis. J Med Virol. 2023;95(7):e28961. (IF=6.8, CI=0) 30. Saito T, Fujisaki T, Aikawa T, Kampaktsis PN, Malik A, Briasoulis A, Takagi H, Wiley J, Slipczuk L, Kuno T. Strategy of dual antiplatelet therapy for patients with ST-elevation myocardial infarction and non-ST-elevation acute coronary syndromes: A systematic review and network meta-analysis. Int J Cardiol. 2023. doi: 10.1016/j.ijcard.2023.131157. (IF=3.5, CI=0) 31. Manabe O, Takahashi K, Kawakami H, Ohtsuka A, Aikawa T, Maki H, Ibe T, Fujita H, Oyama-Manabe N. Diagnostic values of delayed additional FDG PET/CT scan in the evaluation of cardiac sarcoidosis. Ann Nucl Med. 2023. doi: 10.1007/s12149-023-01855-8. (IF=2.6, CI=0) 32. Yasuhara J, Masuda K, Aikawa T, Shirasu T, Takagi H, Lee S, Kuno T. Myopericarditis after COVID-19 mRNA vaccination among adolescents and young adults: a systematic review and meta-analysis. JAMA Pediatr. 2023;177(1):42-52. (IF=26.1, CI=7) 33. Saitou T, Aikawa T,** (Corresponding author, Co-first authors), Manabe O, Nagase A, Kudo T, Oyama-Manabe N. Comparison of 1-h with 3-h planar 99mTc-pyrophosphate scintigraphy in patients with suspected transthyretin cardiac amyloidosis using SPECT as a reference standard. Ann Nucl Med. 2023;37(2):99-107. (IF=2.6, CI=0) 34. Benhuri B, Aikawa T* (*Co-first authors), Takagi H, Benhuri D, Kuno T. Elevated natriuretic peptides in COVID-19 patients with severe or critical illness; a meta-analysis. Tex Heart Inst J. 2022;49(5):e207404. (IF=0.9, CI=0) 35. Aikawa T* (Corresponding author), Kuno T, Van den Eynde J, Briasoulis A, Malik AH. Effects of clinical trial or research program participation status on in-hospital mortality after transcatheter aortic valve implantation. J Am Heart Assoc. 2022;11(12):e025920. (IF=5.0, CI=0) 36. Li J, Kelly SC, Ivey JR, Thorne PK, Yamada KP, Aikawa T, Mazurek R, Turk JR, Silva KAS, Amin AR, Tharp DL, Mueller CM, Thakur H, Leary EV, Domeier TL, Rector RS, Fish K, Cividini F, Ishikawa K, Emter CA, Kapiloff MS. Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion. Physiol Genomics. 2022;54(7):261-272. (IF=4.6, CI=4) 37. Bikou O, Tharakan S, Yamada K, Kariya T, Aguero J, Gordon A, Mazurek R, Aikawa T, Kohlbrenner E, Fish K, Hajjar RJ, Ishikawa K. Endo-bronchial aerosolized AAV1.SERCA2a gene therapy in a pulmonary hypertension pig model: addressing the lung delivery bottleneck. Hum Gene Ther. 2022;33(9-10):550-559. (IF=4.2, CI=1) 38. Aikawa T, Kuno T, Malik AH, Briasoulis A, Latib A. Short-term outcomes after transcatheter aortic valve implantation with or without amyloidosis 2012 to 2019. Am J Cardiol. 2022;169:149-151. (IF=2.3, CI=0) 39. Kawamura I, Aikawa T, Yokoyama Y, Takagi H, Kuno T. Catheter ablation for atrial fibrillation in elderly patients: Systematic review and a meta-analysis. Pacing Clin Electrophysiol. 2022;45(1):59-71. (IF=1.8, CI=3) 40. Sahashi Y, Kawamura I, Aikawa T, Takagi H, Briasoulis A, Kuno T. Safety and feasibility of same-day discharge in patients receiving pulmonary vein isolation-systematic review and a meta-analysis. J Interv Card Electrophysiol. 2022;63(2):251-258. (IF=1.8, CI=3) 41. Naya M, Aikawa T, Manabe O, Obara M, Koyanagawa K, Katoh C, Tamaki N. Elevated serum endothelin-1 is an independent predictor of coronary microvascular dysfunction in non-obstructive territories in patients with coronary artery disease. Heart Vessels. 2021;36(7):917-923. (IF=1.5, CI=9) 42. Tsuneta S, Oyama-Manabe N, Hirata K, Harada T, Aikawa T, Manabe O, Ohira H, Koyanagawa K, Naya M, Kudo K. Texture analysis of delayed contrast-enhanced computed tomography to diagnose cardiac sarcoidosis. Jpn J Radiol. 2021;39(5):442-450. (IF=2.1, CI=6) 43. Manabe O, Aikawa T, Naya M, Miura S, Oyama-Manabe N. Functional assessment of coronary artery disease by myocardial flow reserve versus pressure-wire based assessment. Ann Nucl Cardiol. 2021;7(1):57-62. (IF=-, CI=0) 44. Yokoyama Y, Aikawa T, Takagi H, Briasoulis A, Kuno T. Association of renin-angiotensin-aldosterone system inhibitors with mortality and testing positive of COVID-19: meta-analysis. J Med Virol. 2021;93(4):2084-2089. (IF=6.8, CI=14) 45. Koyanagawa K, Kobayashi Y, Aikawa T (Corresponding author), Takeda A, Shiraishi H, Tsuneta S, Oyama-Manabe N, Iwano H, Nagai T, Anzai T. Myocardial T1-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: early experience. Magn Reson Med Sci. 2021;20(3):320-324. (IF=3.0, CI=1) 46. Aikawa T, Takagi H, Ishikawa K, Kuno T. Myocardial injury characterized by elevated cardiac troponin and in-hospital mortality of COVID-19: an insight from a meta-analysis. J Med Virol. 2021;93(1):51-55. (IF=6.8, CI=29) 47. Furuya S, Naya M, Manabe O, Hirata K, Ohira H, Aikawa T, Koyanagawa K, Magota K, Tsujino I, Anzai T, Kuge Y, Oyama-Manabe N, Kudo K, Shiga T, Tamaki N. 18F-FMISO PET/CT detects hypoxic lesions of cardiac and extra-cardiac involvement in patients with sarcoidosis. J Nucl Cardiol. 2021;28(5):2141-2148. (IF=2.4, CI=18) 48. Koyanagawa K, Naya M, Aikawa T, Manabe O, Furuya S, Kuzume M, Oyama-Manabe N, Ohira H, Tsujino I, Anzai T. The rate of myocardial perfusion recovery after steroid therapy and its implication for cardiac events in cardiac sarcoidosis and primarily preserved left ventricular ejection fraction. J Nucl Cardiol. 2021;28(4):1745-1756. (IF=2.4, CI=5) 49. Koyanagawa K, Naya M, Aikawa T, Manabe O, Kuzume M, Ohira H, Tsujino I, Tamaki N, Anzai T. Prognostic value of phase analysis on gated single photon emission computed tomography in patients with cardiac sarcoidosis. J Nucl Cardiol. 2021;28(1):128-136. (IF=2.4, CI=6) 50. Aikawa T, Kariya T, Yamada KP, Miyashita S, Bikou O, Tharakan S, Fish K, Ishikawa K. Impaired left ventricular global longitudinal strain is associated with elevated left ventricular filling pressure after myocardial infarction. Am J Physiol Heart Circ Physiol. 2020;319(6):H1474-H1481. (IF=4.8, CI=2) 51. Tamaki M, Nakasone H, Aikawa T, Nakamura Y, Kawamura M, Kawamura S, Takeshita J, Yoshino N, Misaki Y, Yoshimura K, Matsumi S, Gomyo A, Tanihara A, Kusuda M, Akahoshi Y, Kimura SI, Kako S, Oyama-Manabe N, Kanda Y. Pre-hematopoietic stem cell transplantation lung computed tomography as an alternative to the pulmonary function test during the COVID-19 pandemic. Biol Blood Marrow Transplant. 2020;26(12):2318-2322. (IF=4.3, CI=2) 52. Aikawa T, Yamaji K, Nagai T, Kohsaka S, Kamiya K, Omote K, Inohara T, Numasawa Y, Tsujita K, Amano T, Ikari Y, Anzai T. Procedural volume and outcomes after percutaneous coronary intervention for unprotected left main coronary artery disease-report from the national clinical data (J-PCI Registry). J Am Heart Assoc. 2020;9(9):e015404. (IF=5.0, CI=12) 53. Manabe O, Koyanagawa K, Hirata K, Oyama-Manabe N, Ohira H, Aikawa T, Furuya S, Naya M, Tsujino I, Tomiyama Y, Otaki Y, Anzai T, Tamaki N. Prognostic value of 18F-FDG PET using texture analysis in cardiac sarcoidosis. JACC Cardiovasc Imaging. 2020;13(4):1096-1097. (IF=14, CI=10) 54. Omote K, Nagai T, Iwano H, Tsujinaga S, Kamiya K, Aikawa T, Konishi T, Sato T, Kato Y, Komoriyama H, Kobayashi Y, Yamamoto K, Yoshikawa T, Saito Y, Anzai T. Left ventricular outflow tract velocity time integral in hospitalized heart failure with preserved ejection fraction. ESC Heart Fail. 2020;7(1):167-175. (IF=3.8, CI=15) 55. Aikawa T, Naya M, Koyanagawa K, Manabe O, Obara M, Magota K, Oyama-Manabe N, Tamaki N, Anzai T. Improved regional myocardial blood flow and flow reserve after coronary revascularization as assessed by serial 15O-water positron emission tomography/computed tomography. Eur Heart J Cardiovasc Imaging. 2020;21(1):36-46. (IF=6.2, CI=12) 56. Omote K, Naya M, Koyanagawa K, Aikawa T, Manabe O, Nagai T, Kamiya K, Kato Y, Komoriyama H, Kuzume M, Tamaki N, Anzai T. 18F-FDG uptake of the right ventricle is an important predictor of histopathologic diagnosis by endomyocardial biopsy in patients with cardiac sarcoidosis. J Nucl Cardiol. 2020;27(6):2135-2143. (IF=2.4, CI=20) 57. Hiroshima Y, Manabe O, Naya M, Tomiyama Y, Magota K, Obara M, Aikawa T, Oyama-Manabe N, Yoshinaga K, Hirata K, Kroenke M, Tamaki N, Katoh C. Quantification of myocardial blood flow with 11C-hydroxyephedrine dynamic PET: comparison with 15O-H2O PET. J Nucl Cardiol. 2020;27(4):1118-1125. (IF=2.4, CI=5) 58. Omote K, Nagai T, Kamiya K, Aikawa T, Tsujinaga S, Kato Y, Komoriyama H, Iwano H, Yamamoto K, Yoshikawa T, Saito Y, Anzai T. Long-term prognostic significance of admission tricuspid regurgitation pressure gradient in hospitalized patients with heart failure with preserved ejection fraction: a report from the Japanese real-world multicenter registry. J Card Fail. 2019;25(12):978-985. (IF=6, CI=10) 59. Aikawa T, Takeda A, Oyama-Manabe N, Naya M, Yamazawa H, Koyanagawa K, Ito YM, Anzai T. Progressive left ventricular dysfunction and myocardial fibrosis in Duchenne and Becker muscular dystrophy: a longitudinal cardiovascular magnetic resonance study. Pediatr Cardiol. 2019;40(2):384-392. (IF=1.6, CI=13) 60. Omote K, Nagai T, Asakawa N, Kamiya K, Tokuda Y, Aikawa T, Fukushima A, Noguchi K, Kato Y, Komoriyama H, Nishida M, Kudo Y, Iwano H, Yokota T, Anzai T. Impact of admission liver stiffness on long-term clinical outcomes in patients with acute decompensated heart failure. Heart Vessels. 2019;34(6):984-991. (IF=1.5, CI=11) 61. Manabe O, Ohira H, Hirata K, Hayashi S, Naya M, Tsujino I, Aikawa T, Koyanagawa K, Oyama-Manabe N, Tomiyama Y, Magota K, Yoshinaga K, Tamaki N. Use of 18F-FDG PET/CT texture analysis to diagnose cardiac sarcoidosis. Eur J Nucl Med Mol Imaging. 2019;46(6):1240-1247. (IF=9.1, CI=24) 62. Kikuchi Y, Naya M, Oyama-Manabe N, Manabe O, Sugimori H, Kudo K, Kato F, Aikawa T, Tsutsui H, Tamaki N, Shirato H. Assessment of coronary flow velocity reserve in the left main trunk by using phase contrast magnetic resonance imaging at 3.0 tesla: comparison with 15O-labeled water positron emission tomography. Magn Reson Med Sci. 2019;18(2):134-141. (IF=3.0, CI=0) 63. Aikawa T, Naya M, Obara M, Manabe O, Magota K, Koyanagawa K, Asakawa N, Ito YM, Shiga T, Katoh C, Anzai T, Tsutsui H, Murthy VL, Tamaki N. Effects of coronary revascularisation on global coronary flow reserve in stable coronary artery disease. Cardiovasc Res. 2019;115(1):119-129. (IF=10.8, CI=17) 64. Manabe O, Kroenke M, Aikawa T, Murayama A, Naya M, Masuda A, Oyama-Manabe N, Hirata K, Watanabe S, Shiga T, Katoh C, Tamaki N. Volume-based glucose metabolic analysis of FDG PET/CT: The optimum threshold and conditions to suppress physiological myocardial uptake. J Nucl Cardiol. 2019;26(3):909-918. (IF=2.4, CI=14) 65. Manabe O, Oyama-Manabe N, Naya M, Obara M, Kikuchi Y, Aikawa T, Tomiyama Y, Sugimori H, Katoh C, Tamaki N, Anzai T. Reduced myocardial flow reserve is associated with subendocardial infarction and coronary stenosis in patients with coronary artery disease: a perfusion MRI study. Cardiovasc Imaging Asia. 2019;3(1):8-14. (IF=-, CI=0) 66. Furuya S, Manabe O, Ohira H, Hirata K, Aikawa T, Naya M, Tsujino I, Koyanagawa K, Anzai T, Oyama-Manabe N, Shiga T. Which is the proper reference tissue for measuring the change in FDG PET metabolic volume of cardiac sarcoidosis before and after steroid therapy? EJNMMI Res. 2018;8(1):94. (IF=3.2, CI=16) 67. Obara M, Naya M, Oyama-Manabe N, Aikawa T, Tomiyama Y, Sasaki T, Kikuchi Y, Manabe O, Katoh C, Tamaki N, Tsutsui H. Diagnostic value of quantitative coronary flow reserve and myocardial blood flow estimated by dynamic 320 MDCT scanning in patients with obstructive coronary artery disease. Medicine (Baltimore). 2018;97(27):e11354. (IF=1.6, CI=5) 68. Sakamoto K, Oyama-Manabe N, Manabe O, Aikawa T, Kikuchi Y, Sasai-Masuko H, Naya M, Kudo K, Kato F, Tamaki N, Shirato H. Heterogeneity of longitudinal and circumferential contraction in relation to late gadolinium enhancement in hypertrophic cardiomyopathy patients with preserved left ventricular ejection fraction. Jpn J Radiol. 2018;36(2):103-112. (IF=2.1, CI=5) 69. Aikawa T, Naya M, Obara M, Oyama-Manabe N, Manabe O, Magota K, Ito YM, Katoh C, Tamaki N. Regional interaction between myocardial sympathetic denervation, contractile dysfunction, and fibrosis in heart failure with preserved ejection fraction: 11C-hydroxyephedrine PET study. Eur J Nucl Med Mol Imaging. 2017;44(11):1897-1905. (IF=9.1, CI=16) 70. Manabe O, Naya M, Aikawa T, Obara M, Magota K, Kroenke M, Oyama-Manabe N, Hirata K, Shinyama D, Katoh C, Tamaki N. PET/CT scanning with 3D acquisition is feasible for quantifying myocardial blood flow when diagnosing coronary artery disease. EJNMMI Res. 2017;7(1):52. (IF=3.2, CI=7) 71. Aikawa T, Oyama-Manabe N, Naya M, Ohira H, Sugimoto A, Tsujino I, Obara M, Manabe O, Kudo K, Tsutsui H, Tamaki N. Delayed contrast-enhanced computed tomography in patients with known or suspected cardiac sarcoidosis: a feasibility study. Eur Radiol. 2017;27(10):4054-4063. (IF=5.9, CI=25) 72. Aikawa T, Naya M, Obara M, Manabe O, Tomiyama Y, Magota K, Yamada S, Katoh C, Tamaki N, Tsutsui H. Impaired myocardial sympathetic innervation is associated with diastolic dysfunction in patients with heart failure with preserved ejection fraction: 11C-hydroxyephedrine PET study. J Nucl Med. 2017;58(5):784-790. (IF=9.3, CI=26) Invited Reviews and Editorials: 73. Oyama-Manabe N, Manabe O, Aikawa T, Sobue Y, Asakura R. Updates on Cardiac MRI and PET Imaging for the Diagnosis and Monitoring of Cardiac Sarcoidosis. Korean J Radiol. 2025;26(9):804-816. 74. Manabe O, Oda S, Norikane T, Aikawa T, Otaki Y, Tamaki N. Advances in imaging-based diagnosis, prognosis, and response assessment in cardiac amyloidosis: a comprehensive multimodality review. Ann Nucl Med. 2025 Aug 25. doi: 10.1007/s12149-025-02092-x. 75. Tamaki N, Aikawa T, Manabe O. 18F-Fluorodeoxyglucose Imaging for Assessing Cardiovascular Inflammation. Diagnostics (Basel). 2025 Feb 27;15(5):573. 76. Aikawa T (Corresponding author). Geographic and ethnic variations in response to lipid-lowering therapies: why do they matter? Eur J Prev Cardiol. 2023;30(11):1118-1119. (IF=8.3, CI=0) 77. Sato T, Aikawa T (Corresponding author). Methotrexate for cardiac sarcoidosis: is it justifiable? J Nucl Cardiol. 2023;30(4):1554-1557. (IF=2.4, CI=0) 78. Aikawa T, Oyama-Manabe N. Editorial for "Comparison of DeepStrain and Feature Tracking for Cardiac MRI Strain Analysis". J Magn Reson Imaging. 2023;57(5):1516-1517. (IF=4.4, CI=1) 79. Sato T, Aikawa T* (Corresponding author). The role of histamine H2 receptor antagonist in heart failure: a potential game-changer? Eur J Prev Cardiol. 2022;29(14):1852-1853. (IF=8.3, CI=0) 80. Oyama-Manabe N, Aikawa T, Tsuneta S, Manabe O. Clinical applications of 4D flow MR imaging in aortic valvular and congenital heart disease. Magn Reson Med Sci. 2022;21(2):319-326. (IF=3.0, CI=7) 81. Manabe O, Oyama-Manabe N, Aikawa T, Tsuneta S, Tamaki N. Advances in Diagnostic Imaging for Cardiac Sarcoidosis. J Clin Med. 2021;10(24):5808. (IF=3.9, CI=1) 82. Oyama-Manabe N, Manabe O, Aikawa T, Tsuneta S. The role of multimodality imaging in cardiac sarcoidosis. Korean Circ J. 2021;51(7):561-578. (IF=2.9, CI=6) 83. Yamada KP, Kariya T, Aikawa T, Ishikawa K. Effects of therapeutic hypothermia on normal and ischemic heart. Front Cardiovasc Med. 2021;8:642843. (IF=3.6, CI=5) 84. Manabe O, Naya M, Aikawa T, Tamaki N. Recent advances in cardiac positron emission tomography for quantitative perfusion analyses and molecular imaging. Ann Nucl Med. 2020;34(10):697-706. (IF=2.6, CI=6) 85. Aikawa T, Nagai T, Anzai T. Serum potassium and glucose levels, and mortality in acute myocardial infarction; fact or myth? Int J Cardiol. 2019;287:50-52. (IF=3.2, CI=0) 86. Manabe O, Naya M, Aikawa T, Yoshinaga K. 15O-labeled water is the best myocardial blood flow tracer for precise MBF quantification. Ann Nucl Cardiol. 2019;5(1):69-72. (IF=-, CI=4) 87. Manabe O, Naya M, Yoshinaga K, Oyama-Manabe N, Ohira H, Aikawa T, Tamaki N. Assessment of myocardial blood flow and cardiac FDG uptake using positron emission tomography. Ann Nucl Cardiol. 2017;3(1):205-209. (IF=-, CI=1) Case reports: 88. Shimabukuro A, Aikawa T (Corresponding author), Matsue Y, Minamino T. Prolonged Fasting Preparation for over 24 Hours Before 18F-fluorodeoxyglucose PET/CT is Useful to Suppress Physiological Myocardial Uptake in Cardiac Sarcoidosis After Steroid Therapy. Ann Nucl Cardiol. 2025;11(1):49-52. 89. Mukai M, Aikawa T(Co-first authors), Matsue Y, Shirane S, Minamino T. Reversible left ventricular dysfunction related to ropeginterferon alfa-2b in polycythemia vera. Int Heart J. 2025;66(6):1033-1035. 90. Shimabukuro A, Aikawa T* (Corresponding author), Iijima K, Minamino T. Gastric distention after catheter ablation for atrial fibrillation. JMA J. 2025, in press. doi: 10.31662/jmaj.2025-0192. 91. Shimabukuro A, Aikawa T (Corresponding author), Kato T, Minamino T. Non-physiological 18F-fluorodeoxyglucose uptake in the myocardium as an early sign of silent myocardial ischemia: an onco-cardiology perspective. Hellenic J Cardiol. 2025 Sep 16:S1109-9666(25)00227-1. 92. Omote K, Aikawa T, Sunaga D, Funayama N. Bright kidney: a sign of contrast induced nephropathy after percutaneous coronary intervention. Oxf Med Case Reports. 2025;2025(7):omaf110. 93. Matsuo R, Aikawa T* (Corresponding author), Inoue H, Kato T, Minamino T. Late-onset pericarditis after autologous myoblast cell-sheet transplantation for ischemic cardiomyopathy. Cardiol J. 2025;32(3):342-343. 94. Abe H, Aikawa T (Corresponding author), Ajima T, Yokoyama K, Minamino T. Treatment of intraprocedural stent thrombosis with intracoronary argatroban injection in ST-segment elevation myocardial infarction. Cardiol J. 2025;32(3):336-337. 95. Omote K, Aikawa T, Ishidoya Y, Sunaga D, Funayama N. Temporary Transvenous Pacemaker Lead-Induced Cardiac Perforation Incidentally Detected by Right Ventriculography Prior to Leadless Pacemaker Implantation. Cureus. 2025;17(5):e84136. 96. Aikawa T* (Corresponding author), Ogino J, Funayama N, Oyama-Manabe N, Minamino T. Vasospastic angina as a cause of post-acute sequelae of COVID-19. Int Heart J. 2025;66(3):504-510. 97. Shimabukuro A, Aikawa T (Corresponding author), Fujimoto S, Minamino T. Unusual intrathoracic uptake of 99mTc-tetrofosmin on myocardial perfusion imaging. J Nucl Cardiol. 2025 Mar 28:102198. doi: 10.1016/j.nuclcard.2025.102198. 98. Omote K, Oi M, Aikawa T (Corresponding author). Serial assessment of diffusion-weighted whole-body magnetic resonance imaging with background body signal suppression and 18F-fluorodeoxyglcose positron emission tomography/computed tomography after corticosteroid therapy in Takayasu arteritis. J Nucl Cardiol. 2025 Aug;50:102171. doi: 10.1016/j.nuclcard.2025.102171. 99. Abe H, Aikawa T (Corresponding author), Yokoyama K, Minamino T. Successful bailout of catheter-induced dissection in acute myocardial infarction resulting from a nondominant right coronary artery occlusion. Case Rep Cardiol. 2024;2024:1091601. 100. Omote K, Oi M, Aikawa T (Corresponding author). Diffusion-weighted whole-body MRI with background body signal suppression and 18F-FDG PET/CT in patients with Takayasu arteritis. Can J Cardiol. 2024;40(12):2392-2394. 101. Abe H, Aikawa T (Corresponding author), Yokoyama K, Minamino T. Coronary artery ectasia with plaque erosion in acute coronary syndrome. Cardiovasc Revasc Med. 2024;65:104-106. (IF=1.6, CI=-) 102. Aikawa T (Corresponding author), Funayama N, Sunaga D, Minamino T. Retrieval of entrapped coronary balloon catheter with goose neck snare. Cardiovasc Revasc Med. 2024;61:116-117. (IF=1.6, CI=-) 103. Manabe O, Jinnouchi H, Aikawa T, Shirai K, Oyama-Manabe N. Ischaemia in the right ventricle and left ventricle, and rheumatoid myalgia incidentally found in a lung cancer patient treated with immune checkpoint inhibitors: a case report with 18F-fluorodeoxyglucose-positron emission tomography/computed tomography imaging. Eur Heart J Cardiovasc Imaging. 2023;25(1):e58. (IF=6.2, CI=-) 104. Manabe O, Tsukui T, Yoshimura K, Oshiro H, Oyama-Manabe N, Aikawa T, Takahashi K, Sakakura K, Fujita H. 18F-FDG PET/CT findings in autopsy confirmed a case of ischemic cardiac disease at an early stage. Eur J Nucl Med Mol Imaging. 2023;50(7):2224-2225. (IF=9.1, CI=0) 105. Aikawa T, Manabe O, Ibe T, Oyama-Manabe N. Serial assessment of cardiac involvement in sarcoidosis by delayed 18F-fluorodeoxyglucose PET/CT. J Nucl Cardiol. 2023;30(5):2225-2228. (IF=2.4, CI=1) 106. Kato S*, Aikawa T (Co-first authors), Ibe T, Manabe O, Oyama-Manabe N. Delayed 18F-fluorodeoxyglucose PET/CT imaging improves detection of cardiac involvement in sarcoidosis. J Nucl Cardiol. 2023;30(1):417-419. (IF=2.4, CI=2) 107. Aikawa T (Corresponding author), Kamada R, Ogino J, Saitou T, Funayama N, Hotta D. Cardiac resynchronization therapy through a subcutaneous tunnel assessed by phase analysis of gated myocardial perfusion SPECT imaging. J Nucl Cardiol. 2023;30(3):1277-1282. (IF=2.4, CI=0) 108. Aikawa T (Corresponding author), Ogino J, Oyama-Manabe N, Funayama N. Vasospastic Angina: A Cause of Post-acute COVID-19 Syndrome. Intern Med. 2022;61(17):2693-2695. (IF=1.2, CI=1) 109. Aikawa T (Corresponding author), Ogino J, Aikawa N, Oyama-Manabe N. Pericarditis with increased vascular permeability after COVID-19 vaccination. Intern Med. 2022;61(10):1623-1624. (IF=1.2, CI=0) 110. Aikawa T (Corresponding author), Funayama N, Sunaga D, Furugen M, Hotta D. Treatment of an iatrogenic left main coronary artery dissection and intramural hematoma by fenestration instead of stent implantation. Hellenic J Cardiol. 2022;65:61-63. (IF=4.1, CI=0) 111. Aikawa T, Ibe T, Manabe O, Oyama-Manabe N. Imaging of idiopathic restrictive cardiomyopathy: a multimodality approach. Intern Med. 2022;61(20):3145-3147. (IF=1.2, CI=0) 112. Aikawa T* (Corresponding author), Ogino J, Kita Y, Funayama N, Oyama-Manabe N. Non-infectious endocarditis and myocarditis after COVID-19 mRNA vaccination. Eur Heart J Case Rep. 2022;6(1):ytab533. (IF=1.0, CI=4) 113. Maki H, Aikawa T* (*Co-first authors), Ibe T, Oyama-Manabe N, Fujita H. Biventricular systolic dysfunction in acute myocarditis after SARS-CoV-2 mRNA-1273 vaccination. Eur Heart J Cardiovasc Imaging. 2022;23(2):e87. (IF=6.2, CI=7) 114. Aikawa T, Maki H, Ibe T, Manabe O, Oyama-Manabe N. Interatrial septal 99mTc-pyrophosphate uptake and reduced strain in wild-type transthyretin amyloid cardiomyopathy. J Nucl Cardiol. 2022;29(1):363-366. (IF=2.4, CI=2) 115. Aikawa T, Ibe T, Manabe O, Oyama-Manabe N. Right ventricular involvement of cardiac sarcoidosis: a comprehensive evaluation using cardiovascular magnetic resonance imaging and positron emission tomography. J Nucl Cardiol. 2022;29(6):3593-3595. (IF=2.4, CI=2) 116. Aikawa T, Ibe T, Manabe O, Oyama-Manabe N. Biventricular and right atrial thrombi in a middle-aged woman. Eur Heart J Case Rep. 2021;6(1):ytab509. (IF=1.0, CI=0) 117. Aikawa T (Corresponding author), Ogino J, Kita Y, Funayama N. Myocardial microthrombi after COVID-19 mRNA vaccination. Eur Heart J. 2021;42(43):4501. (IF=39.3, CI=5) 118. Aikawa T (Corresponding author), Ogino J, Hirofuji A, Oyama-Manabe N. Microvascular thrombi in recurrent myocardial injury after coronavirus disease 2019 infection. Eur Heart J. 2021;42(36):3804. (IF=39.3, CI=2) 119. Aikawa T (Corresponding author), Funayama N, Sunaga D, Kayanuma K, Oyama-Manabe N, Hotta D. Reverse redistribution-like change on dipyridamole-stress 99mTc-tetrofosmin imaging in a patient with angiographically mild coronary artery stenosis. J Nucl Cardiol. 2021;28(3):1182-1185. (IF=2.4, CI=0) 120. Aikawa T (Corresponding author), Ogino J, Kudo T, Kashiwagi Y. Late-onset endocarditis after coronavirus disease 2019 infection. Eur Heart J. 2021;42(32):3108. (IF=39.3, CI=2) 121. Chiba Y, Kamiya K, Aikawa T, Iwano H, Nagai T, Ishigaki T, Shingu Y, Shimizu A, Matsui Y, Anzai T. Abnormal FDG uptake predicting the instability of thoracic aortic aneurysms. J Nucl Cardiol. 2020;27(5):1841-1843. (IF=2.4, CI=0) 122. Aikawa T* (Corresponding author), Koyanagawa K, Oyama-Manabe N, Anzai T. Cardiac sarcoidosis mimicking myocardial infarction: a comprehensive evaluation using computed tomography and positron emission tomography. J Nucl Cardiol. 2020;27(3):1066-1067. (IF=2.4, CI=3) 123. Aikawa T (Corresponding author), Kamiya K, Mitsuhashi T, Anzai T. Endomyocardial fibrosis presenting as apical calcification and infective endocarditis. Eur Heart J. 2019;40(12):1016. (IF=39.3, CI=1) 124. Manabe O, Oyama-Manabe N, Naya M, Aikawa T, Sakakibara M, Tsutsui H, Tamaki N. Pitfalls of 18F-FDG PET for evaluating myocardial viability. J Nucl Cardiol. 2017;24(3):1110-1113. (IF=2.4, CI=3) 125. Aikawa T, Naya M, Oyama-Manabe N, Maekawa S, Nambu H, Mitsuyama H, Hirata K, Kanno-Okada H, Tsutsui H. 18F-FDG PET findings of pericardial lymphangiohemangioma. J Nucl Cardiol. 2017;24(3):1107-1109. (IF=2.4, CI=1) 126. Aikawa T, Naya M, Manabe O, Obara M, Matsushima S, Tamaki N, Tsutsui H. Incidental focal myocardial 18F-FDG uptake indicating asymptomatic coronary artery disease. J Nucl Cardiol. 2016;23(3):596-8. (IF=2.4, CI=6) 127. Aikawa T* (*Corresponding author), Sakakibara M, Takahashi M, Asakawa K, Dannoura Y, Makino T, Koya T, Tsutsui H. Critical takotsubo cardiomyopathy complicated by ventricular septal perforation. Intern Med. 2015;54(1):37-41. (IF=1.2, CI=11)

研究テーマ

心血管病における最先端画像診断装置を用いた非侵襲的定量評価法の開発と臨床応用

研究業績（論文）

英文業績 (*Corresponding author)
Original articles:
1. Saitou T, Manabe O, Nagase A, Toyama H, Kudo T, Oyama-Manabe N, Aikawa T* (*Corresponding author). Impact of region of interest size on semiquantitative evaluation of myocardial 99mTc-pyrophosphate uptake in suspected transthyretin cardiac amyloidosis. Ann Nucl Cardiol. 2025;11(1):33-38.
2. Kiyohara Y, Aikawa T, Saito T, Casso Dominguez A, Wiley J, Kolte D, Secemsky EA, Yeh RW, Laham RJ, Latib A, Bhatt DL, Kuno T*. Comparison of limus and paclitaxel drug-coated balloons, second-generation or newer drug-eluting stents, and balloon angioplasty: a network meta-analysis of randomized controlled trials. Circ Cardiovasc Interv. 2025 Oct 27:e016005.
3. Asanuma T, Hiruma Y, Watanabe A, Shimoda TM, Iwagami M, Hosseini K, Slipczuk L, Wiley J, Briasoulis A, Takagi H, Aikawa T, Kuno T*. Efficacy and safety of direct oral anticoagulants versus vitamin K antagonist in patients with left ventricular thrombus: A meta-analysis of randomized controlled trials. J Cardiol. 2025 Dec;86(6):618-621.
4. Aikawa T* (*Corresponding author), Mori Y, Kohsaka S, Matsue Y, Kuno T, Yamaji K, Ozaki D, Tokano T, Kozuma K, Minamino T. Application and outcomes of coronary atherectomy in acute coronary syndrome: a report from the J-PCI Registry. J Soc Cardiovasc Angiogr Interv. 2025;4(7):103622.
5. Tanimoto K*, Kawamura Y, Kimura S, Hasuike Y, Tachibana E, Kudo A, Aikawa T, Murakami K, Fujimoto S. SPECT reconstruction using preprocessing masking for extra-cardiac uptake versus standard processing in 99mTc-sestamibi myocardial perfusion imaging. Ann Nucl Med. 2025 Aug 26. doi: 10.1007/s12149-025-02085-w.
6. Watanabe A, Aikawa T, Miyamoto Y, Ueyama HA, Fujisaki T, Shoji S, Hosseini K, Slipczuk L, Briasoulis A, Kampaktsis PN, Wiley J, Secemsky EA, Iwagami M, Tsugawa Y, Kuno T*. Ticagrelor paradox: systematic review and network meta-analysis. J Am Heart Assoc. 2025 Sep 2;14(17):e041959.
7. Ajima T**, Aikawa T*,** (*Corresponding author, **Co-first authors), Saitou T, Matsue Y, Fujimoto S, Omote K, Minamino T. Prognostic value of 99mTc-pyrophosphate uptake in patients with suspected transthyretin cardiac amyloidosis. J Nucl Cardiol. 2025 Aug 5:102452. doi: 10.1016/j.nuclcard.2025.102452.
8. Saito T, Miyamoto Y, Fujisaki T, Ueyama H, Watanabe A, Hosseini K, Briasoulis A, Slipczuk L, Takagi H, Shoji S, Iwagami M, Kolte D, Aikawa T, Lavie CJ, Kuno T*. Sex Differences in Safety and Efficacy of Dual Antiplatelet Therapy Strategies for Patients With Acute Coronary Syndromes: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Am J Cardiol. 2025 Jul 20;256:81-88.
9. Hashimoto K, Fujisaki T, Aikawa T, Iwagami M, Miyamoto Y, Slipczuk L, Biase LD, Briasoulis A, Yasuhara J, Takagi H, Kuno T*. Optimal Thromboembolism Prevention for Patients With Atrial Fibrillation on Long-Term Dialysis. Pacing Clin Electrophysiol. 2025 Jul;48(7):733-753.
10. Tomizawa N*, Fan R, Fujimoto S, Nozaki YO, Kawaguchi YO, Takamura K, Hiki M, Aikawa T, Takahashi N, Okai I, Okazaki S, Kumamaru KK, Minamino T, Aoki S. High-resolution deep learning reconstruction to improve the accuracy of CT fractional flow reserve. Eur Radiol. 2025 May 22. doi: 10.1007/s00330-025-11707-w.
11. Tomizawa N*, Ozu H, Kamio S, Fujimoto S, Nozaki YO, Fan R, Kawaguchi YO, Takamura K, Hiki M, Aikawa T, Kadowaki S, Ikeda F, Kumamaru KK, Watada H, Minamino T, Aoki S. Effect of sampling rate during dynamic myocardial CT perfusion on coronary flow reserve and ischemia analysis. Int J Cardiovasc Imaging. 2025;41(4):743-753.
12. Kani R, Miyamoto Y, Saito T, Watanabe A, Matsubara K, Ejiri K, Iwagami M, Slipczuk L, Hosseini K, Fujisaki T, Takagi H, Yaku H, Aikawa T, Kuno T*. Racial and regional differences in efficacy of sodium-glucose cotransporter 2 inhibitors on cardiorenal outcomes: A systematic review and meta-analysis. Int J Cardiol. 2025;426:133079.
13. Saito T, Watanabe A, Aikawa T, Kapur NK, Kuno T*. Comparison of temporary mechanical circulatory support devices for patients with cardiogenic shock after acute myocardial infarction: A network meta-analysis of randomized controlled trials. Int J Cardiol. 2025;423:132997.
14. Mavropoulos SA, Aikawa T, Mazurek R, Sakata T, Yamada K, Watanabe K, Sunagawa G, Veera S, Singleton DT, Leonard K, Kariya T, Sahoo S, Ishikawa K*. A minimally invasive swine model of chronic kidney disease-associated heart failure. Am J Physiol Heart Circ Physiol. 2025;328(2):H260-H270.
15. Saitou T**, Aikawa T*,** (*Corresponding author, **Co-first authors), Manabe O, Fujimoto S, Matsue Y, Nagase A, Toyama H, Kudo T, Oyama-Manabe N, Minamino T. Lateral planar imaging of 99mTc-pyrophosphate scintigraphy in patients with suspected transthyretin cardiac amyloidosis. Ann Nucl Cardiol. 2024;10(1):29-37. (IF=-, CI=0)
16. Saito T, Kuno T*, Aikawa T, Ueyama HA, Kampaktsis PN, Kolte D, Misumida N, Takagi H, Ahmad Y, Kaneko T, Zajarias A, Latib A. Long-term outcomes with medical therapy, transcatheter repair, or surgery for isolated tricuspid regurgitation: a systematic review and network meta-analysis. Clin Res Cardiol. 2025;114(2):272-280.
17. Odagiri F*, Tokano T, Miyazaki T, Hirabayashi K, Ishi K, Abe H, Ishiwata S, Kakihara M, Maki M, Matsumoto H, Shimai R, Aikawa T, Takano S, Kimura Y, Kuroda S, Isogai H, Ozaki D, Shiozawa T, Yasuda Y, Takasu K, Iijima K, Takamura K, Matsubara T, Tabuchi H, Hayashi H, Yokoyama K, Sekita G, Sumiyoshi M, Nakazato Y, Minamino T. Clinical impact of cryoballoon posterior wall isolation using the cross-over technique in persistent atrial fibrillation. Pacing Clin Electrophysiol. 2024;47(10):1326-1337.
18. Xu Y, Korayem A, Cruz-Solbes AS, Chandel N, Sakata T, Mazurek R, Mavropoulos SA, Kariya T, Aikawa T, Yamada KP, D'Escamard V, V'Gangula B, Baker AH, Ma L, Björkegren JLM, Fuster V, Boehm M, Fish KM, Tadros R, Ishikawa K, Kovacic JC*. Inhibition of endothelial-to-mesenchymal transition in a large animal preclinical arteriovenous fistula model leads to improved remodelling and reduced stenosis. Cardiovasc Res. 2024;120(14):1768-1779.
19. Kani R, Watanabe A, Miyamoto Y, Ejiri K, Iwagami M, Takagi H, Slipczuk L, Tsugawa Y, Aikawa T, Kuno T*. Comparison of effectiveness among different sodium-glucose cotransoporter-2 inhibitors according to underlying conditions: a network meta-analysis of randomized controlled trials. J Am Heart Assoc. 2024;13(3):e031805. (IF=5.0, CI=3)
20. Saito T, Kuno T*, Ueyama HA, Kampaktsis PN, Kolte D, Misumida N, Takagi H, Aikawa T, Latib A*. Transcatheter edge-to-edge mitral valve repair for mitral regurgitation in patients with cardiogenic shock: A systematic review and meta-analysis. Catheter Cardiovasc Interv. 2023. doi: 10.1002/ccd.30944. (IF=2.1, CI=2)
21. Kuno T*, Yamaji K, Aikawa T, Sawano M, Ando T, Numasawa Y, Wada H, Amano T, Kozuma K, Kohsaka S. Transradial intervention in dialysis patients undergoing percutaneous coronary intervention: a Japanese nationwide registry study. Eur Heart J Open. 2023;3(6):oead116. (IF=-, CI=0)
22. Abe H, Miyazaki T*, Tomaru M, Nobushima Y, Ajima T, Hirabayashi K, Ishiwata S, Kakihara M, Maki M, Shimai R, Aikawa T, Isogai H, Ozaki D, Yasuda Y, Odagiri F, Takamura K, Hiki M, Iwata H, Yokoyama K, Tokano T, Minamino T. Poor nutritional status during recovery from acute myocardial infarction in patients without an early nutritional intervention predicts a poor prognosis: a single-center retrospective study. Nutrients. 2023;15(22):4748. (IF=4.8, CI=0)
23. Kiyohara Y**, Aikawa T** (**Co-first authors), Kayanuma K, Takagi H, Kampaktsis PN, Wiley J, Kuno T*. Comparison of clinical outcomes among various percutaneous coronary intervention strategies for small coronary artery disease. Am J Cardiol. 2024;211:334-342. (IF=2.3, CI=2)
24. Aikawa T, Kuno T*, Malik AH, Briasoulis A, Kolte D, Kampaktsis PN, Latib A. Transcatheter aortic valve replacement in patients with or without active cancer. J Am Heart Assoc. 2023;12(21):e030072. (IF=5.0, CI=0)
25. Ishisaka Y, Watanabe A, Aikawa T, Kanaoka K, Takagi H, Wiley J, Yasuhara J, Kuno T*. Overview of SARS-CoV-2 infection and vaccine associated myocarditis compared to non-COVID-19-associated myocarditis: A systematic review and meta-analysis. Int J Cardiol. 2024;395:131401. (IF=3.2, CI=5)
26. Tsukagoshi J, Shimoda T, Yokoyama Y, Secemsky EA, Shirasu T, Nakama T, Jujo K, Wiley J, Takagi H, Aikawa T, Kuno T*. The mid-term effect of intravascular ultrasound on endovascular interventions for lower extremity peripheral arterial disease: a systematic review and meta-analysis. J Vasc Surg. 2023:S0741-5214(23)01942-0. (IF=3.9, CI=2)
27. Hamada S, Ueyama H, Aikawa T, Kampaktsis PN, Misumida N, Takagi H, Kuno T*, Latib A*. Outcomes of transcatheter edge-to-edge repair for atrial functional mitral regurgitation: A meta-analysis of observational studies. Catheter Cardiovasc Interv. 2023;102(4):751-760. (IF=2.1, CI=1)
28. Ishisaka Y, Aikawa T, Malik A, Kampaktsis PN, Briasoulis A, Kuno T*. Association of Remdesivir use with bradycardia: A systematic review and meta-analysis. J Med Virol. 2023;95(8):e29018. (IF=6.8, CI=4)
29. Watanabe A, Malik A, Aikawa T, Briasoulis A, Kuno T*. Extracorporeal membrane oxygenation for COVID-19-associated acute respiratory distress syndrome: A nationwide analysis. J Med Virol. 2023;95(7):e28961. (IF=6.8, CI=0)
30. Saito T, Fujisaki T, Aikawa T, Kampaktsis PN, Malik A, Briasoulis A, Takagi H, Wiley J, Slipczuk L, Kuno T*. Strategy of dual antiplatelet therapy for patients with ST-elevation myocardial infarction and non-ST-elevation acute coronary syndromes: A systematic review and network meta-analysis. Int J Cardiol. 2023. doi: 10.1016/j.ijcard.2023.131157. (IF=3.5, CI=0)
31. Manabe O, Takahashi K, Kawakami H, Ohtsuka A, Aikawa T, Maki H, Ibe T, Fujita H, Oyama-Manabe N*. Diagnostic values of delayed additional FDG PET/CT scan in the evaluation of cardiac sarcoidosis. Ann Nucl Med. 2023. doi: 10.1007/s12149-023-01855-8. (IF=2.6, CI=0)
32. Yasuhara J*, Masuda K, Aikawa T, Shirasu T, Takagi H, Lee S, Kuno T*. Myopericarditis after COVID-19 mRNA vaccination among adolescents and young adults: a systematic review and meta-analysis. JAMA Pediatr. 2023;177(1):42-52. (IF=26.1, CI=7)
33. Saitou T**, Aikawa T*,** (*Corresponding author, **Co-first authors), Manabe O**, Nagase A, Kudo T, Oyama-Manabe N. Comparison of 1-h with 3-h planar 99mTc-pyrophosphate scintigraphy in patients with suspected transthyretin cardiac amyloidosis using SPECT as a reference standard. Ann Nucl Med. 2023;37(2):99-107. (IF=2.6, CI=0)
34. Benhuri B**, Aikawa T** (**Co-first authors), Takagi H, Benhuri D, Kuno T*. Elevated natriuretic peptides in COVID-19 patients with severe or critical illness; a meta-analysis. Tex Heart Inst J. 2022;49(5):e207404. (IF=0.9, CI=0)
35. Aikawa T* (*Corresponding author), Kuno T, Van den Eynde J, Briasoulis A, Malik AH. Effects of clinical trial or research program participation status on in-hospital mortality after transcatheter aortic valve implantation. J Am Heart Assoc. 2022;11(12):e025920. (IF=5.0, CI=0)
36. Li J, Kelly SC, Ivey JR, Thorne PK, Yamada KP, Aikawa T, Mazurek R, Turk JR, Silva KAS, Amin AR, Tharp DL, Mueller CM, Thakur H, Leary EV, Domeier TL, Rector RS, Fish K, Cividini F, Ishikawa K*, Emter CA*, Kapiloff MS*. Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion. Physiol Genomics. 2022;54(7):261-272. (IF=4.6, CI=4)
37. Bikou O, Tharakan S, Yamada K, Kariya T, Aguero J, Gordon A, Mazurek R, Aikawa T, Kohlbrenner E, Fish K, Hajjar RJ, Ishikawa K*. Endo-bronchial aerosolized AAV1.SERCA2a gene therapy in a pulmonary hypertension pig model: addressing the lung delivery bottleneck. Hum Gene Ther. 2022;33(9-10):550-559. (IF=4.2, CI=1)
38. Aikawa T, Kuno T*, Malik AH, Briasoulis A, Latib A. Short-term outcomes after transcatheter aortic valve implantation with or without amyloidosis 2012 to 2019. Am J Cardiol. 2022;169:149-151. (IF=2.3, CI=0)
39. Kawamura I, Aikawa T, Yokoyama Y, Takagi H, Kuno T*. Catheter ablation for atrial fibrillation in elderly patients: Systematic review and a meta-analysis. Pacing Clin Electrophysiol. 2022;45(1):59-71. (IF=1.8, CI=3)
40. Sahashi Y, Kawamura I, Aikawa T, Takagi H, Briasoulis A, Kuno T*. Safety and feasibility of same-day discharge in patients receiving pulmonary vein isolation-systematic review and a meta-analysis. J Interv Card Electrophysiol. 2022;63(2):251-258. (IF=1.8, CI=3)
41. Naya M*, Aikawa T, Manabe O, Obara M, Koyanagawa K, Katoh C, Tamaki N. Elevated serum endothelin-1 is an independent predictor of coronary microvascular dysfunction in non-obstructive territories in patients with coronary artery disease. Heart Vessels. 2021;36(7):917-923. (IF=1.5, CI=9)
42. Tsuneta S, Oyama-Manabe N*, Hirata K, Harada T, Aikawa T, Manabe O, Ohira H, Koyanagawa K, Naya M, Kudo K. Texture analysis of delayed contrast-enhanced computed tomography to diagnose cardiac sarcoidosis. Jpn J Radiol. 2021;39(5):442-450. (IF=2.1, CI=6)
43. Manabe O, Aikawa T, Naya M, Miura S, Oyama-Manabe N*. Functional assessment of coronary artery disease by myocardial flow reserve versus pressure-wire based assessment. Ann Nucl Cardiol. 2021;7(1):57-62. (IF=-, CI=0)
44. Yokoyama Y, Aikawa T, Takagi H, Briasoulis A, Kuno T*. Association of renin-angiotensin-aldosterone system inhibitors with mortality and testing positive of COVID-19: meta-analysis. J Med Virol. 2021;93(4):2084-2089. (IF=6.8, CI=14)
45. Koyanagawa K, Kobayashi Y, Aikawa T (*Corresponding author)*, Takeda A, Shiraishi H, Tsuneta S, Oyama-Manabe N, Iwano H, Nagai T, Anzai T. Myocardial T1-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: early experience. Magn Reson Med Sci. 2021;20(3):320-324. (IF=3.0, CI=1)
46. Aikawa T, Takagi H, Ishikawa K, Kuno T*. Myocardial injury characterized by elevated cardiac troponin and in-hospital mortality of COVID-19: an insight from a meta-analysis. J Med Virol. 2021;93(1):51-55. (IF=6.8, CI=29)
47. Furuya S, Naya M, Manabe O*, Hirata K, Ohira H, Aikawa T, Koyanagawa K, Magota K, Tsujino I, Anzai T, Kuge Y, Oyama-Manabe N, Kudo K, Shiga T, Tamaki N. 18F-FMISO PET/CT detects hypoxic lesions of cardiac and extra-cardiac involvement in patients with sarcoidosis. J Nucl Cardiol. 2021;28(5):2141-2148. (IF=2.4, CI=18)
48. Koyanagawa K, Naya M*, Aikawa T, Manabe O, Furuya S, Kuzume M, Oyama-Manabe N, Ohira H, Tsujino I, Anzai T. The rate of myocardial perfusion recovery after steroid therapy and its implication for cardiac events in cardiac sarcoidosis and primarily preserved left ventricular ejection fraction. J Nucl Cardiol. 2021;28(4):1745-1756. (IF=2.4, CI=5)
49. Koyanagawa K, Naya M*, Aikawa T, Manabe O, Kuzume M, Ohira H, Tsujino I, Tamaki N, Anzai T. Prognostic value of phase analysis on gated single photon emission computed tomography in patients with cardiac sarcoidosis. J Nucl Cardiol. 2021;28(1):128-136. (IF=2.4, CI=6)
50. Aikawa T, Kariya T, Yamada KP, Miyashita S, Bikou O, Tharakan S, Fish K, Ishikawa K*. Impaired left ventricular global longitudinal strain is associated with elevated left ventricular filling pressure after myocardial infarction. Am J Physiol Heart Circ Physiol. 2020;319(6):H1474-H1481. (IF=4.8, CI=2)
51. Tamaki M, Nakasone H, Aikawa T, Nakamura Y, Kawamura M, Kawamura S, Takeshita J, Yoshino N, Misaki Y, Yoshimura K, Matsumi S, Gomyo A, Tanihara A, Kusuda M, Akahoshi Y, Kimura SI, Kako S, Oyama-Manabe N, Kanda Y*. Pre-hematopoietic stem cell transplantation lung computed tomography as an alternative to the pulmonary function test during the COVID-19 pandemic. Biol Blood Marrow Transplant. 2020;26(12):2318-2322. (IF=4.3, CI=2)
52. Aikawa T, Yamaji K, Nagai T*, Kohsaka S, Kamiya K, Omote K, Inohara T, Numasawa Y, Tsujita K, Amano T, Ikari Y, Anzai T. Procedural volume and outcomes after percutaneous coronary intervention for unprotected left main coronary artery disease-report from the national clinical data (J-PCI Registry). J Am Heart Assoc. 2020;9(9):e015404. (IF=5.0, CI=12)
53. Manabe O, Koyanagawa K, Hirata K*, Oyama-Manabe N, Ohira H, Aikawa T, Furuya S, Naya M, Tsujino I, Tomiyama Y, Otaki Y, Anzai T, Tamaki N. Prognostic value of 18F-FDG PET using texture analysis in cardiac sarcoidosis. JACC Cardiovasc Imaging. 2020;13(4):1096-1097. (IF=14, CI=10)
54. Omote K, Nagai T*, Iwano H, Tsujinaga S, Kamiya K, Aikawa T, Konishi T, Sato T, Kato Y, Komoriyama H, Kobayashi Y, Yamamoto K, Yoshikawa T, Saito Y, Anzai T. Left ventricular outflow tract velocity time integral in hospitalized heart failure with preserved ejection fraction. ESC Heart Fail. 2020;7(1):167-175. (IF=3.8, CI=15)
55. Aikawa T, Naya M*, Koyanagawa K, Manabe O, Obara M, Magota K, Oyama-Manabe N, Tamaki N, Anzai T. Improved regional myocardial blood flow and flow reserve after coronary revascularization as assessed by serial 15O-water positron emission tomography/computed tomography. Eur Heart J Cardiovasc Imaging. 2020;21(1):36-46. (IF=6.2, CI=12)
56. Omote K, Naya M*, Koyanagawa K, Aikawa T, Manabe O, Nagai T, Kamiya K, Kato Y, Komoriyama H, Kuzume M, Tamaki N, Anzai T. 18F-FDG uptake of the right ventricle is an important predictor of histopathologic diagnosis by endomyocardial biopsy in patients with cardiac sarcoidosis. J Nucl Cardiol. 2020;27(6):2135-2143. (IF=2.4, CI=20)
57. Hiroshima Y, Manabe O*, Naya M, Tomiyama Y, Magota K, Obara M, Aikawa T, Oyama-Manabe N, Yoshinaga K, Hirata K, Kroenke M, Tamaki N, Katoh C. Quantification of myocardial blood flow with 11C-hydroxyephedrine dynamic PET: comparison with 15O-H2O PET. J Nucl Cardiol. 2020;27(4):1118-1125. (IF=2.4, CI=5)
58. Omote K, Nagai T*, Kamiya K, Aikawa T, Tsujinaga S, Kato Y, Komoriyama H, Iwano H, Yamamoto K, Yoshikawa T, Saito Y, Anzai T. Long-term prognostic significance of admission tricuspid regurgitation pressure gradient in hospitalized patients with heart failure with preserved ejection fraction: a report from the Japanese real-world multicenter registry. J Card Fail. 2019;25(12):978-985. (IF=6, CI=10)
59. Aikawa T, Takeda A, Oyama-Manabe N*, Naya M, Yamazawa H, Koyanagawa K, Ito YM, Anzai T. Progressive left ventricular dysfunction and myocardial fibrosis in Duchenne and Becker muscular dystrophy: a longitudinal cardiovascular magnetic resonance study. Pediatr Cardiol. 2019;40(2):384-392. (IF=1.6, CI=13)
60. Omote K, Nagai T*, Asakawa N, Kamiya K, Tokuda Y, Aikawa T, Fukushima A, Noguchi K, Kato Y, Komoriyama H, Nishida M, Kudo Y, Iwano H, Yokota T, Anzai T. Impact of admission liver stiffness on long-term clinical outcomes in patients with acute decompensated heart failure. Heart Vessels. 2019;34(6):984-991. (IF=1.5, CI=11)
61. Manabe O, Ohira H, Hirata K*, Hayashi S, Naya M, Tsujino I, Aikawa T, Koyanagawa K, Oyama-Manabe N, Tomiyama Y, Magota K, Yoshinaga K, Tamaki N. Use of 18F-FDG PET/CT texture analysis to diagnose cardiac sarcoidosis. Eur J Nucl Med Mol Imaging. 2019;46(6):1240-1247. (IF=9.1, CI=24)
62. Kikuchi Y, Naya M*, Oyama-Manabe N, Manabe O, Sugimori H, Kudo K, Kato F, Aikawa T, Tsutsui H, Tamaki N, Shirato H. Assessment of coronary flow velocity reserve in the left main trunk by using phase contrast magnetic resonance imaging at 3.0 tesla: comparison with 15O-labeled water positron emission tomography. Magn Reson Med Sci. 2019;18(2):134-141. (IF=3.0, CI=0)
63. Aikawa T, Naya M*, Obara M, Manabe O, Magota K, Koyanagawa K, Asakawa N, Ito YM, Shiga T, Katoh C, Anzai T, Tsutsui H, Murthy VL, Tamaki N. Effects of coronary revascularisation on global coronary flow reserve in stable coronary artery disease. Cardiovasc Res. 2019;115(1):119-129. (IF=10.8, CI=17)
64. Manabe O*, Kroenke M, Aikawa T, Murayama A, Naya M, Masuda A, Oyama-Manabe N, Hirata K, Watanabe S, Shiga T, Katoh C, Tamaki N. Volume-based glucose metabolic analysis of FDG PET/CT: The optimum threshold and conditions to suppress physiological myocardial uptake. J Nucl Cardiol. 2019;26(3):909-918. (IF=2.4, CI=14)
65. Manabe O, Oyama-Manabe N, Naya M, Obara M, Kikuchi Y, Aikawa T, Tomiyama Y, Sugimori H, Katoh C, Tamaki N, Anzai T. Reduced myocardial flow reserve is associated with subendocardial infarction and coronary stenosis in patients with coronary artery disease: a perfusion MRI study. Cardiovasc Imaging Asia. 2019;3(1):8-14. (IF=-, CI=0)
66. Furuya S, Manabe O*, Ohira H, Hirata K, Aikawa T, Naya M, Tsujino I, Koyanagawa K, Anzai T, Oyama-Manabe N, Shiga T. Which is the proper reference tissue for measuring the change in FDG PET metabolic volume of cardiac sarcoidosis before and after steroid therapy? EJNMMI Res. 2018;8(1):94. (IF=3.2, CI=16)
67. Obara M, Naya M, Oyama-Manabe N*, Aikawa T, Tomiyama Y, Sasaki T, Kikuchi Y, Manabe O, Katoh C, Tamaki N, Tsutsui H. Diagnostic value of quantitative coronary flow reserve and myocardial blood flow estimated by dynamic 320 MDCT scanning in patients with obstructive coronary artery disease. Medicine (Baltimore). 2018;97(27):e11354. (IF=1.6, CI=5)
68. Sakamoto K, Oyama-Manabe N*, Manabe O, Aikawa T, Kikuchi Y, Sasai-Masuko H, Naya M, Kudo K, Kato F, Tamaki N, Shirato H. Heterogeneity of longitudinal and circumferential contraction in relation to late gadolinium enhancement in hypertrophic cardiomyopathy patients with preserved left ventricular ejection fraction. Jpn J Radiol. 2018;36(2):103-112. (IF=2.1, CI=5)
69. Aikawa T, Naya M*, Obara M, Oyama-Manabe N, Manabe O, Magota K, Ito YM, Katoh C, Tamaki N. Regional interaction between myocardial sympathetic denervation, contractile dysfunction, and fibrosis in heart failure with preserved ejection fraction: 11C-hydroxyephedrine PET study. Eur J Nucl Med Mol Imaging. 2017;44(11):1897-1905. (IF=9.1, CI=16)
70. Manabe O, Naya M*, Aikawa T, Obara M, Magota K, Kroenke M, Oyama-Manabe N, Hirata K, Shinyama D, Katoh C, Tamaki N. PET/CT scanning with 3D acquisition is feasible for quantifying myocardial blood flow when diagnosing coronary artery disease. EJNMMI Res. 2017;7(1):52. (IF=3.2, CI=7)
71. Aikawa T, Oyama-Manabe N*, Naya M, Ohira H, Sugimoto A, Tsujino I, Obara M, Manabe O, Kudo K, Tsutsui H, Tamaki N. Delayed contrast-enhanced computed tomography in patients with known or suspected cardiac sarcoidosis: a feasibility study. Eur Radiol. 2017;27(10):4054-4063. (IF=5.9, CI=25)
72. Aikawa T, Naya M*, Obara M, Manabe O, Tomiyama Y, Magota K, Yamada S, Katoh C, Tamaki N, Tsutsui H. Impaired myocardial sympathetic innervation is associated with diastolic dysfunction in patients with heart failure with preserved ejection fraction: 11C-hydroxyephedrine PET study. J Nucl Med. 2017;58(5):784-790. (IF=9.3, CI=26)
Invited Reviews and Editorials:
73. Oyama-Manabe N*, Manabe O, Aikawa T, Sobue Y, Asakura R. Updates on Cardiac MRI and PET Imaging for the Diagnosis and Monitoring of Cardiac Sarcoidosis. Korean J Radiol. 2025;26(9):804-816.
74. Manabe O*, Oda S, Norikane T, Aikawa T, Otaki Y, Tamaki N. Advances in imaging-based diagnosis, prognosis, and response assessment in cardiac amyloidosis: a comprehensive multimodality review. Ann Nucl Med. 2025 Aug 25. doi: 10.1007/s12149-025-02092-x.
75. Tamaki N*, Aikawa T, Manabe O. 18F-Fluorodeoxyglucose Imaging for Assessing Cardiovascular Inflammation. Diagnostics (Basel). 2025 Feb 27;15(5):573.
76. Aikawa T* (*Corresponding author). Geographic and ethnic variations in response to lipid-lowering therapies: why do they matter? Eur J Prev Cardiol. 2023;30(11):1118-1119. (IF=8.3, CI=0)
77. Sato T, Aikawa T* (*Corresponding author). Methotrexate for cardiac sarcoidosis: is it justifiable? J Nucl Cardiol. 2023;30(4):1554-1557. (IF=2.4, CI=0)
78. Aikawa T, Oyama-Manabe N*. Editorial for "Comparison of DeepStrain and Feature Tracking for Cardiac MRI Strain Analysis". J Magn Reson Imaging. 2023;57(5):1516-1517. (IF=4.4, CI=1)
79. Sato T, Aikawa T* (*Corresponding author). The role of histamine H2 receptor antagonist in heart failure: a potential game-changer? Eur J Prev Cardiol. 2022;29(14):1852-1853. (IF=8.3, CI=0)
80. Oyama-Manabe N*, Aikawa T, Tsuneta S, Manabe O. Clinical applications of 4D flow MR imaging in aortic valvular and congenital heart disease. Magn Reson Med Sci. 2022;21(2):319-326. (IF=3.0, CI=7)
81. Manabe O, Oyama-Manabe N*, Aikawa T, Tsuneta S, Tamaki N. Advances in Diagnostic Imaging for Cardiac Sarcoidosis. J Clin Med. 2021;10(24):5808. (IF=3.9, CI=1)
82. Oyama-Manabe N*, Manabe O, Aikawa T, Tsuneta S. The role of multimodality imaging in cardiac sarcoidosis. Korean Circ J. 2021;51(7):561-578. (IF=2.9, CI=6)
83. Yamada KP, Kariya T, Aikawa T, Ishikawa K*. Effects of therapeutic hypothermia on normal and ischemic heart. Front Cardiovasc Med. 2021;8:642843. (IF=3.6, CI=5)
84. Manabe O, Naya M*, Aikawa T, Tamaki N. Recent advances in cardiac positron emission tomography for quantitative perfusion analyses and molecular imaging. Ann Nucl Med. 2020;34(10):697-706. (IF=2.6, CI=6)
85. Aikawa T, Nagai T*, Anzai T. Serum potassium and glucose levels, and mortality in acute myocardial infarction; fact or myth? Int J Cardiol. 2019;287:50-52. (IF=3.2, CI=0)
86. Manabe O, Naya M, Aikawa T, Yoshinaga K*. 15O-labeled water is the best myocardial blood flow tracer for precise MBF quantification. Ann Nucl Cardiol. 2019;5(1):69-72. (IF=-, CI=4)
87. Manabe O*, Naya M, Yoshinaga K, Oyama-Manabe N, Ohira H, Aikawa T, Tamaki N. Assessment of myocardial blood flow and cardiac FDG uptake using positron emission tomography. Ann Nucl Cardiol. 2017;3(1):205-209. (IF=-, CI=1)
Case reports:
88. Shimabukuro A, Aikawa T* (*Corresponding author), Matsue Y, Minamino T. Prolonged Fasting Preparation for over 24 Hours Before 18F-fluorodeoxyglucose PET/CT is Useful to Suppress Physiological Myocardial Uptake in Cardiac Sarcoidosis After Steroid Therapy. Ann Nucl Cardiol. 2025;11(1):49-52.
89. Mukai M**, Aikawa T**(**Co-first authors), Matsue Y*, Shirane S, Minamino T. Reversible left ventricular dysfunction related to ropeginterferon alfa-2b in polycythemia vera. Int Heart J. 2025;66(6):1033-1035.
90. Shimabukuro A, Aikawa T* (*Corresponding author), Iijima K, Minamino T. Gastric distention after catheter ablation for atrial fibrillation. JMA J. 2025, in press. doi: 10.31662/jmaj.2025-0192.
91. Shimabukuro A, Aikawa T* (*Corresponding author), Kato T, Minamino T. Non-physiological 18F-fluorodeoxyglucose uptake in the myocardium as an early sign of silent myocardial ischemia: an onco-cardiology perspective. Hellenic J Cardiol. 2025 Sep 16:S1109-9666(25)00227-1.
92. Omote K*, Aikawa T, Sunaga D, Funayama N. Bright kidney: a sign of contrast induced nephropathy after percutaneous coronary intervention. Oxf Med Case Reports. 2025;2025(7):omaf110.
93. Matsuo R, Aikawa T* (*Corresponding author), Inoue H, Kato T, Minamino T. Late-onset pericarditis after autologous myoblast cell-sheet transplantation for ischemic cardiomyopathy. Cardiol J. 2025;32(3):342-343.
94. Abe H, Aikawa T* (*Corresponding author), Ajima T, Yokoyama K, Minamino T. Treatment of intraprocedural stent thrombosis with intracoronary argatroban injection in ST-segment elevation myocardial infarction. Cardiol J. 2025;32(3):336-337.
95. Omote K*, Aikawa T, Ishidoya Y, Sunaga D, Funayama N. Temporary Transvenous Pacemaker Lead-Induced Cardiac Perforation Incidentally Detected by Right Ventriculography Prior to Leadless Pacemaker Implantation. Cureus. 2025;17(5):e84136.
96. Aikawa T* (*Corresponding author), Ogino J, Funayama N, Oyama-Manabe N, Minamino T. Vasospastic angina as a cause of post-acute sequelae of COVID-19. Int Heart J. 2025;66(3):504-510.
97. Shimabukuro A, Aikawa T* (*Corresponding author), Fujimoto S, Minamino T. Unusual intrathoracic uptake of 99mTc-tetrofosmin on myocardial perfusion imaging. J Nucl Cardiol. 2025 Mar 28:102198. doi: 10.1016/j.nuclcard.2025.102198.
98. Omote K, Oi M, Aikawa T* (*Corresponding author). Serial assessment of diffusion-weighted whole-body magnetic resonance imaging with background body signal suppression and 18F-fluorodeoxyglcose positron emission tomography/computed tomography after corticosteroid therapy in Takayasu arteritis. J Nucl Cardiol. 2025 Aug;50:102171. doi: 10.1016/j.nuclcard.2025.102171.
99. Abe H, Aikawa T* (*Corresponding author), Yokoyama K, Minamino T. Successful bailout of catheter-induced dissection in acute myocardial infarction resulting from a nondominant right coronary artery occlusion. Case Rep Cardiol. 2024;2024:1091601.
100. Omote K, Oi M, Aikawa T* (*Corresponding author). Diffusion-weighted whole-body MRI with background body signal suppression and 18F-FDG PET/CT in patients with Takayasu arteritis. Can J Cardiol. 2024;40(12):2392-2394.
101. Abe H, Aikawa T* (*Corresponding author), Yokoyama K, Minamino T. Coronary artery ectasia with plaque erosion in acute coronary syndrome. Cardiovasc Revasc Med. 2024;65:104-106. (IF=1.6, CI=-)
102. Aikawa T* (*Corresponding author), Funayama N, Sunaga D, Minamino T. Retrieval of entrapped coronary balloon catheter with goose neck snare. Cardiovasc Revasc Med. 2024;61:116-117. (IF=1.6, CI=-)
103. Manabe O, Jinnouchi H, Aikawa T, Shirai K, Oyama-Manabe N*. Ischaemia in the right ventricle and left ventricle, and rheumatoid myalgia incidentally found in a lung cancer patient treated with immune checkpoint inhibitors: a case report with 18F-fluorodeoxyglucose-positron emission tomography/computed tomography imaging. Eur Heart J Cardiovasc Imaging. 2023;25(1):e58. (IF=6.2, CI=-)
104. Manabe O, Tsukui T, Yoshimura K, Oshiro H, Oyama-Manabe N*, Aikawa T, Takahashi K, Sakakura K, Fujita H. 18F-FDG PET/CT findings in autopsy confirmed a case of ischemic cardiac disease at an early stage. Eur J Nucl Med Mol Imaging. 2023;50(7):2224-2225. (IF=9.1, CI=0)
105. Aikawa T, Manabe O*, Ibe T, Oyama-Manabe N. Serial assessment of cardiac involvement in sarcoidosis by delayed 18F-fluorodeoxyglucose PET/CT. J Nucl Cardiol. 2023;30(5):2225-2228. (IF=2.4, CI=1)
106. Kato S**, *Aikawa T** (**Co-first authors), Ibe T, Manabe O, Oyama-Manabe N*. Delayed 18F-fluorodeoxyglucose PET/CT imaging improves detection of cardiac involvement in sarcoidosis. J Nucl Cardiol. 2023;30(1):417-419. (IF=2.4, CI=2)
107. Aikawa T* (*Corresponding author), Kamada R, Ogino J, Saitou T, Funayama N, Hotta D. Cardiac resynchronization therapy through a subcutaneous tunnel assessed by phase analysis of gated myocardial perfusion SPECT imaging. J Nucl Cardiol. 2023;30(3):1277-1282. (IF=2.4, CI=0)
108. Aikawa T* (*Corresponding author), Ogino J, Oyama-Manabe N, Funayama N. Vasospastic Angina: A Cause of Post-acute COVID-19 Syndrome. Intern Med. 2022;61(17):2693-2695. (IF=1.2, CI=1)
109. Aikawa T* (*Corresponding author), Ogino J, Aikawa N, Oyama-Manabe N. Pericarditis with increased vascular permeability after COVID-19 vaccination. Intern Med. 2022;61(10):1623-1624. (IF=1.2, CI=0)
110. Aikawa T* (*Corresponding author), Funayama N, Sunaga D, Furugen M, Hotta D. Treatment of an iatrogenic left main coronary artery dissection and intramural hematoma by fenestration instead of stent implantation. Hellenic J Cardiol. 2022;65:61-63. (IF=4.1, CI=0)
111. Aikawa T, Ibe T, Manabe O, Oyama-Manabe N*. Imaging of idiopathic restrictive cardiomyopathy: a multimodality approach. Intern Med. 2022;61(20):3145-3147. (IF=1.2, CI=0)
112. Aikawa T* (*Corresponding author), Ogino J, Kita Y, Funayama N, Oyama-Manabe N. Non-infectious endocarditis and myocarditis after COVID-19 mRNA vaccination. Eur Heart J Case Rep. 2022;6(1):ytab533. (IF=1.0, CI=4)
113. Maki H**, Aikawa T** (**Co-first authors), Ibe T, Oyama-Manabe N*, Fujita H. Biventricular systolic dysfunction in acute myocarditis after SARS-CoV-2 mRNA-1273 vaccination. Eur Heart J Cardiovasc Imaging. 2022;23(2):e87. (IF=6.2, CI=7)
114. Aikawa T, Maki H, Ibe T, Manabe O, Oyama-Manabe N*. Interatrial septal 99mTc-pyrophosphate uptake and reduced strain in wild-type transthyretin amyloid cardiomyopathy. J Nucl Cardiol. 2022;29(1):363-366. (IF=2.4, CI=2)
115. Aikawa T, Ibe T, Manabe O, Oyama-Manabe N*. Right ventricular involvement of cardiac sarcoidosis: a comprehensive evaluation using cardiovascular magnetic resonance imaging and positron emission tomography. J Nucl Cardiol. 2022;29(6):3593-3595. (IF=2.4, CI=2)
116. Aikawa T, Ibe T, Manabe O, Oyama-Manabe N*. Biventricular and right atrial thrombi in a middle-aged woman. Eur Heart J Case Rep. 2021;6(1):ytab509. (IF=1.0, CI=0)
117. Aikawa T* (*Corresponding author), Ogino J, Kita Y, Funayama N. Myocardial microthrombi after COVID-19 mRNA vaccination. Eur Heart J. 2021;42(43):4501. (IF=39.3, CI=5)
118. Aikawa T* (*Corresponding author), Ogino J, Hirofuji A, Oyama-Manabe N. Microvascular thrombi in recurrent myocardial injury after coronavirus disease 2019 infection. Eur Heart J. 2021;42(36):3804. (IF=39.3, CI=2)
119. Aikawa T* (*Corresponding author), Funayama N, Sunaga D, Kayanuma K, Oyama-Manabe N, Hotta D. Reverse redistribution-like change on dipyridamole-stress 99mTc-tetrofosmin imaging in a patient with angiographically mild coronary artery stenosis. J Nucl Cardiol. 2021;28(3):1182-1185. (IF=2.4, CI=0)
120. Aikawa T* (*Corresponding author), Ogino J, Kudo T, Kashiwagi Y. Late-onset endocarditis after coronavirus disease 2019 infection. Eur Heart J. 2021;42(32):3108. (IF=39.3, CI=2)
121. Chiba Y, Kamiya K*, Aikawa T, Iwano H, Nagai T, Ishigaki T, Shingu Y, Shimizu A, Matsui Y, Anzai T. Abnormal FDG uptake predicting the instability of thoracic aortic aneurysms. J Nucl Cardiol. 2020;27(5):1841-1843. (IF=2.4, CI=0)
122. Aikawa T* (*Corresponding author), Koyanagawa K, Oyama-Manabe N, Anzai T. Cardiac sarcoidosis mimicking myocardial infarction: a comprehensive evaluation using computed tomography and positron emission tomography. J Nucl Cardiol. 2020;27(3):1066-1067. (IF=2.4, CI=3)
123. Aikawa T* (*Corresponding author), Kamiya K, Mitsuhashi T, Anzai T. Endomyocardial fibrosis presenting as apical calcification and infective endocarditis. Eur Heart J. 2019;40(12):1016. (IF=39.3, CI=1)
124. Manabe O, Oyama-Manabe N*, Naya M, Aikawa T, Sakakibara M, Tsutsui H, Tamaki N. Pitfalls of 18F-FDG PET for evaluating myocardial viability. J Nucl Cardiol. 2017;24(3):1110-1113. (IF=2.4, CI=3)
125. Aikawa T, Naya M*, Oyama-Manabe N, Maekawa S, Nambu H, Mitsuyama H, Hirata K, Kanno-Okada H, Tsutsui H. 18F-FDG PET findings of pericardial lymphangiohemangioma. J Nucl Cardiol. 2017;24(3):1107-1109. (IF=2.4, CI=1)
126. Aikawa T, Naya M*, Manabe O, Obara M, Matsushima S, Tamaki N, Tsutsui H. Incidental focal myocardial 18F-FDG uptake indicating asymptomatic coronary artery disease. J Nucl Cardiol. 2016;23(3):596-8. (IF=2.4, CI=6)
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