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向田宏（ムカイダヒロシ）

研究テーマ	体外循環技術
研究業績（論文）	1. Go Sato, Hidetoshi Nojiri, Hiromitsu Takano, Hiroshi Mukaida, Muneaki Ishijima. Investigation of the relationship between intraoperative transcranial motor evoked potential and compound muscle action potential in corrective spinal deformity surgery. Juntendo Med J. 2026. 2. Ricard Ferrer, Koki Namekawa, Shunichiro Urabe, Hiroshi Mukaida, Nao Umei, Toshiaki Iba. Endotoxin activity assay-guided polymyxin B hemoperfusion: from failed trials to biological enrichment: Juntendo Med J. 2026. 3. Mukaida H, Minami Y. Goal-directed perfusion during cardiopulmonary bypass: Physiological rationale, clinical evidence, and critical appraisal. Perfusion. 2026 Apr 20:2676591261446139. doi: 10.1177/02676591261446139. Epub ahead of print. PMID: 42008651. Corresponding author 4. Minami Y, Mukaida H, Sato G, Yasumoto H, Sugawara K, Usuba M, Kojima R, Tabata M, Association between core body temperature at the time of separation from cardiopulmonary bypass and postoperative acute kidney injury: A retrospective observational study. J Cardiothorac Vasc Anesth. 2026 Mar 21:S1053-0770(26)00254-5. doi: 10.1053/j.jvca.2026.03.029. Epub ahead of print. Corresponding author 5. Mukaida H, Matsushita S, Yamamoto T, Minami Y, Sato Go, Asai T, Amano A. Oxygen delivery-guided perfusion for the prevention of acute kidney injury: A randomized controlled trial. J Thorac Cardiovasc Surg. 2023; 165(2):750-760.e5 6. Mukaida H, Matsushita S, Minami Y, Sato G, Usuba M, Kondo R, Asai T, Amano A. Risk factors for postoperative delirium on oxygen delivery-guided perfusion. J Cardiothorac Surg. 2022 Aug 20;17(1):193. 7. Matsushita S, Kishida A, Wakamatsu Y, Mukaida H, Yokokawa H, Yamamoto T, Amano A. Factors influencing activated clotting time following heparin administration for the initiation of cardiopulmonary bypass. Gen Thorac Cardiovasc Surg. 2021 Jan;69(1):38-43. 8. 向田宏、松下訓、長嶋耕平、田端実、天野篤：人工心肺管理における酸素供給量と静脈血酸素飽和度を用いた適正灌流の指標の検討　2施設共同観察研究；体外循環技術 47巻1号：28-34、2020. 9. Mukaida H, Hayashida M, Matsushita S, Endo D, Oishi A, Shimada A, Hata H, Kajimoto K, Yamamoto T, Amano A. Free triiodothyronine (fT3) and B-type natriuretic peptide (BNP) predict in-hospital mortality after valve surgery. Gen Thorac Cardiovasc Surg. 2020 Jun;68(6):585-595. 10. Takano AM, Iwata H, Miyosawa K, Kimura A, 〇Mukaida H, Osawa S, Kubota K, Doi S, Funamizu T, Takasu K, Okai I, Tamura H, Isoda K, Okazaki S, Suwa S, Miyauchi K, Sumiyoshi M, Amano A, Daida H. Reduced Number of Platelets During Intra-Aortic Balloon Pumping Counterpulsation Predicts Higher Cardiovascular Mortality After Device Removal in Association with Systemic Inflammation. Int Heart J. 2020 Jan 31;61(1):89-95. 11. Mmukaida H, Matsushita, S., Kuwaki, K., Inotani, T., Minami, Y., Saigusa, A. Amano A. Time–dose response of oxygen delivery during cardiopulmonary bypass predicts acute kidney injury. J Thorac Cardiovasc Surg. 2019 Aug;158(2):492-499. 12. Mukaida H, Matsushita S, Inotani T, Nakamura A, Amano A. Continuous renal replacement therapy with a polymethyl methacrylate membrane hemofilter suppresses inflammation in patients after open-heart surgery with cardiopulmonary bypass. J Artif Organs. 2018 Jun;21(2):188-195. 13. Mukaida H, Hayashida M, Matsushita S, Yamamoto M, Nakamura A, Amano A. Brain natriuretic peptide (BNP) may play a major role in risk stratification based on cerebral oxygen saturation by near-infrared spectroscopy in patients undergoing major cardiovascular surgery. PLoS One. 2017 Jul 12;12(7): e0181154. 14. Yamamoto M, Hayashida M, Kakemizu-Watanabe M, Ando N, 〇Mukaida H, Kawagoe I, Yusuke S, Inada E. B-Type Natriuretic Peptide and Hemoglobin are Two Major Factors Significantly Associated With Baseline Cerebral Oxygen Saturation Measured Using the INVOS Oximeter in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery. J Cardiothorac Vasc Anesth. 2017 Apr 13. 15. Takano A, Sekita G, Watanabe M, 〇Mukaida H, Komatsu S, Tabuchi H, Hayashi H, Tokano T, Sumiyoshi M, Nakazato Y, Daida H. Long-term reliability of sweet-tip type screw-in leads. J Arrhythm. 2017 Feb;33(1):12-16. 16. Mukaida H, Matsushita S, Inotani T, Futaki S, Takano A, Watanabe M, Morita T, Miida T, Amano A：Peripheral circulation evaluation with near-infrared spectroscopy in skeletal muscle during cardiopulmonary bypass．2015； Perfusion 30(8)：653-659 17. 向田宏、中村淳史、山本裕美子、猪谷卓弘、天野篤、代田浩之：糖尿病患者における常温人工心肺中のヘモグロビン酸素解離能からみた酸素需給バランス．体外循環技術(0912-2664)40巻2号：139-148、2013

研究テーマ

体外循環技術

研究業績（論文）

1. Go Sato, Hidetoshi Nojiri, Hiromitsu Takano, Hiroshi Mukaida, Muneaki Ishijima. Investigation of the relationship between intraoperative transcranial motor evoked potential and compound muscle action potential in corrective spinal deformity surgery. Juntendo Med J. 2026.
2. Ricard Ferrer, Koki Namekawa, Shunichiro Urabe, Hiroshi Mukaida, Nao Umei, Toshiaki Iba. Endotoxin activity assay-guided polymyxin B hemoperfusion: from failed trials to biological enrichment: Juntendo Med J. 2026.
3. Mukaida H, Minami Y. Goal-directed perfusion during cardiopulmonary bypass: Physiological rationale, clinical evidence, and critical appraisal. Perfusion. 2026 Apr 20:2676591261446139. doi: 10.1177/02676591261446139. Epub ahead of print. PMID: 42008651. Corresponding author
4. Minami Y, Mukaida H, Sato G, Yasumoto H, Sugawara K, Usuba M, Kojima R, Tabata M, Association between core body temperature at the time of separation from cardiopulmonary bypass and postoperative acute kidney injury: A retrospective observational study. J Cardiothorac Vasc Anesth. 2026 Mar 21:S1053-0770(26)00254-5. doi: 10.1053/j.jvca.2026.03.029. Epub ahead of print. Corresponding author
5. Mukaida H, Matsushita S, Yamamoto T, Minami Y, Sato Go, Asai T, Amano A. Oxygen delivery-guided perfusion for the prevention of acute kidney injury: A randomized controlled trial. J Thorac Cardiovasc Surg. 2023; 165(2):750-760.e5
6. Mukaida H, Matsushita S, Minami Y, Sato G, Usuba M, Kondo R, Asai T, Amano A. Risk factors for postoperative delirium on oxygen delivery-guided perfusion. J Cardiothorac Surg. 2022 Aug 20;17(1):193.
7. Matsushita S, Kishida A, Wakamatsu Y, Mukaida H, Yokokawa H, Yamamoto T, Amano A. Factors influencing activated clotting time following heparin administration for the initiation of cardiopulmonary bypass. Gen Thorac Cardiovasc Surg. 2021 Jan;69(1):38-43.
8. 向田宏、松下訓、長嶋耕平、田端実、天野篤：人工心肺管理における酸素供給量と静脈血酸素飽和度を用いた適正灌流の指標の検討　2施設共同観察研究；体外循環技術 47巻1号：28-34、2020.
9. Mukaida H, Hayashida M, Matsushita S, Endo D, Oishi A, Shimada A, Hata H, Kajimoto K, Yamamoto T, Amano A. Free triiodothyronine (fT3) and B-type natriuretic peptide (BNP) predict in-hospital mortality after valve surgery. Gen Thorac Cardiovasc Surg. 2020 Jun;68(6):585-595.
10. Takano AM, Iwata H, Miyosawa K, Kimura A, 〇Mukaida H, Osawa S, Kubota K, Doi S, Funamizu T, Takasu K, Okai I, Tamura H, Isoda K, Okazaki S, Suwa S, Miyauchi K, Sumiyoshi M, Amano A, Daida H. Reduced Number of Platelets During Intra-Aortic Balloon Pumping Counterpulsation Predicts Higher Cardiovascular Mortality After Device Removal in Association with Systemic Inflammation. Int Heart J. 2020 Jan 31;61(1):89-95.
11. Mmukaida H, Matsushita, S., Kuwaki, K., Inotani, T., Minami, Y., Saigusa, A. Amano A. Time–dose response of oxygen delivery during cardiopulmonary bypass predicts acute kidney injury. J Thorac Cardiovasc Surg. 2019 Aug;158(2):492-499.
12. Mukaida H, Matsushita S, Inotani T, Nakamura A, Amano A. Continuous renal replacement therapy with a polymethyl methacrylate membrane hemofilter suppresses inflammation in patients after open-heart surgery with cardiopulmonary bypass. J Artif Organs. 2018 Jun;21(2):188-195.
13. Mukaida H, Hayashida M, Matsushita S, Yamamoto M, Nakamura A, Amano A. Brain natriuretic peptide (BNP) may play a major role in risk stratification based on cerebral oxygen saturation by near-infrared spectroscopy in patients undergoing major cardiovascular surgery. PLoS One. 2017 Jul 12;12(7): e0181154.
14. Yamamoto M, Hayashida M, Kakemizu-Watanabe M, Ando N, 〇Mukaida H, Kawagoe I, Yusuke S, Inada E. B-Type Natriuretic Peptide and Hemoglobin are Two Major Factors Significantly Associated With Baseline Cerebral Oxygen Saturation Measured Using the INVOS Oximeter in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery. J Cardiothorac Vasc Anesth. 2017 Apr 13.
15. Takano A, Sekita G, Watanabe M, 〇Mukaida H, Komatsu S, Tabuchi H, Hayashi H, Tokano T, Sumiyoshi M, Nakazato Y, Daida H. Long-term reliability of sweet-tip type screw-in leads. J Arrhythm. 2017 Feb;33(1):12-16.
16. Mukaida H, Matsushita S, Inotani T, Futaki S, Takano A, Watanabe M, Morita T, Miida T, Amano A：Peripheral circulation evaluation with near-infrared spectroscopy in skeletal muscle during cardiopulmonary bypass．2015； Perfusion 30(8)：653-659
17. 向田宏、中村淳史、山本裕美子、猪谷卓弘、天野篤、代田浩之：糖尿病患者における常温人工心肺中のヘモグロビン酸素解離能からみた酸素需給バランス．体外循環技術(0912-2664)40巻2号：139-148、2013

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【学校法人順天堂】研究者情報データベース

研究業績詳細

向田 宏（ムカイダ ヒロシ）

向田宏（ムカイダヒロシ）