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研究業績詳細
洲崎 悦生（スサキ エツオ）
| 研究テーマ | 多細胞システム解析手法の開発と、個体老化を中心とした医学生物学研究への応用 |
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| 研究業績（論文） | ‡co-first *corresponding Etsuo A Susaki*. Unlocking the potential of large-scale 3D imaging with tissue clearing techniques. Microscopy (Oxford, England), dfae046, 2024. Rin Yanai‡, Tomoki T Mitani‡, Etsuo A Susaki‡, Takeharu Minamihisamatsu, Masafumi Shimojo, Yuri Saito, Hiroshi Mizuma, Nobuhiro Nitta, Daita Kaneda, Yoshio Hashizume, Gen Matsumoto, Kentaro Tanemura, Ming-Rong Zhang, Makoto Higuchi, Hiroki R Ueda, Naruhiko Sahara. A novel tauopathy model mimicking molecular and spatial aspects of human tau pathology. Brain communications, 6(5):fcae326, 2024. Tomoki T Mitani‡, Etsuo A Susaki‡, Katsuhiko Matsumoto, Hiroki R Ueda. Realization of cellomics to dive into the whole-body or whole-organ cell cloud. Nature methods, 21(7):1138-1142, 2024. Kohei Otomo, Takaki Omura, Yuki Nozawa, Steven J Edwards, Yukihiko Sato, Yuri Saito, Shigehiro Yagishita, Hitoshi Uchida, Yuki Watakabe, Kiyotada Naitou, Rin Yanai, Naruhiko Sahara, Satoshi Takagi, Ryohei Katayama, Yusuke Iwata, Toshiro Shiokawa, Yoku Hayakawa, Kensuke Otsuka, Haruko Watanabe-Takano, Yuka Haneda, Shigetomo Fukuhara, Miku Fujiwara, Takenobu Nii, Chikara Meno, Naoki Takeshita, Kenta Yashiro, Juan Marcelo Rosales Rocabado, Masaru Kaku, Tatsuya Yamada, Yumiko Oishi, Hiroyuki Koike, Yinglan Cheng, Keisuke Sekine, Jun-Ichiro Koga, Kaori Sugiyama, Kenichi Kimura, Fuyuki Karube, Hyeree Kim, Ichiro Manabe, Tomomi Nemoto, Kazuki Tainaka, Akinobu Hamada, Hjalmar Brismar, Etsuo A Susaki*. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques. Nature communications, 15(1):4941, 2024. Akira Leon Yoshikawa, Takaki Omura, Atsushi Takahashi‐Kanemitsu, Etsuo A. Susaki*. Blueprints from plane to space: outlook of next‐generation three‐dimensional histopathology Cancer Science, 115(4):1029–1038, 2024. Atsushi Takahashi-Kanemitsu, Mengxue Lu, Christopher Takaya Knight, Takayoshi Yamamoto, Takuo Hayashi, Yusuke Mii, Takuya Ooki, Ippei Kikuchi, Akira Kikuchi, Nick Barker, Etsuo A Susaki, Masanori Taira, Masanori Hatakeyama. The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells. Science signaling, 16(794):eabp9020, 2023. Adam K Glaser, Kevin W Bishop, Lindsey A Barner, Etsuo A Susaki, Shimpei I Kubota, Gan Gao, Robert B Serafin, Pooja Balaram, Emily Turschak, Philip R Nicovich, Hoyin Lai, Luciano A G Lucas, Yating Yi, Eva K Nichols, Hongyi Huang, Nicholas P Reder, Jasmine J Wilson, Ramya Sivakumar, Elya Shamskhou, Caleb R Stoltzfus, Xing Wei, Andrew K Hempton, Marko Pende, Prayag Murawala, Hans-Ulrich Dodt, Takato Imaizumi, Jay Shendure, Brian J Beliveau, Michael Y Gerner, Li Xin, Hu Zhao, Lawrence D True, R Clay Reid, Jayaram Chandrashekar, Hiroki R Ueda, Karel Svoboda, Jonathan T C Liu. A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues. Nature methods, 19(5):613-619, 2022. Tomoyuki Mano, Ken Murata, Kazuhiro Kon, Chika Shimizu, Hiroaki Ono, Shoi Shi, Rikuhiro G. Yamada, Kazunari Miyamichi, Etsuo A. Susaki, Kazushige Touhara, Hiroki R. Ueda. CUBIC-Cloud provides an integrative computational framework toward community-driven whole-mouse-brain mapping. Cell Reports Methods, 1(2):100038, 2021. Etsuo A Susaki*, Minoru Takasato. Perspective: Extending the Utility of Three-Dimensional Organoids by Tissue Clearing Technologies. Frontiers in cell and developmental biology, 9():679226-, 2021. Etsuo A Susaki*, Chika Shimizu, Akihiro Kuno, Kazuki Tainaka, Xiang Li, Kengo Nishi, Ken Morishima, Hiroaki Ono, Koji L Ode, Yuki Saeki, Kazunari Miyamichi, Kaoru Isa, Chihiro Yokoyama, Hiroki Kitaura, Masako Ikemura, Tetsuo Ushiku, Yoshihiro Shimizu, Takashi Saito, Takaomi C Saido, Masashi Fukayama, Hirotaka Onoe, Kazushige Touhara, Tadashi Isa, Akiyoshi Kakita, Mitsuhiro Shibayama, Hiroki R Ueda*. Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues. Nature Communications, 11(1):1982, 2020. Susaki EA, Ukai H, Ueda HR. Next-generation mammalian genetics toward organism-level systems biology. npj Systems Biology and Applications, 3:15, 2017. Koji L. Ode‡, Hideki Ukai‡, Etsuo A. Susaki‡, Ryohei Narumi, Katsuhiko Matsumoto, Junko Hara, Naoshi Koide, Takaya Abe, Masato T. Kanemaki, Hiroshi Kiyonari, Hiroki R. Ueda. Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1. Molecular Cell, 65(1):176-190, 2017. Fumiya Tatsuki‡, Genshiro A. Sunagawa‡, Shoi Shi‡, Etsuo A. Susaki‡, Hiroko Yukinaga‡, Dimitri Perrin‡, Kenta Sumiyama, Maki Ukai-Tadenuma, Hiroshi Fujishima, Rei-ichiro Ohno, Daisuke Tone, Koji L. Ode, Katsuhiko Matsumoto, and Hiroki R. Ueda. Involvement of Ca2+-Dependent Hyperpolarization in Sleep Duration in Mammals. Neuron, 90(1):70-85, 2016. Etsuo A. Susaki, Hiroki R. Ueda. Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals. Cell Chemical Biology, 23(1):137-157, 2016. Etsuo A. Susaki‡, Kazuki Tainaka‡, Dimitri Perrin‡, Hiroko Yukinaga, Akihiro Kuno, Hiroki R. Ueda. Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging. Nature Protocols, 10(11):1709-1727, 2015. Etsuo A. Susaki‡, Kazuki Tainaka‡, Dimitri Perrin‡, Fumiaki Kishino, Takehiro Tawara, Tomonobu M. Watanabe, Chihiro Yokoyama, Hirotaka Onoe, Megumi Eguchi, Shun Yamaguchi, Takaya Abe, Hiroshi Kiyonari, Yoshihiro Shimizu, Atsushi Miyawaki, Hideo Yokota, Hiroki R. Ueda. Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis. Cell, 157(3):726-739, 2014. |
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