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GUSEV OLEG（グセフオレグ）

研究テーマ	Regulatory transcriptomics of human development and deseases
研究業績（論文）	1: Belott CJ, Gusev OA, Kikawada T, Menze MA. Membraneless and membrane-bound organelles in an anhydrobiotic cell line are protected from desiccation-induced damage. Cell Stress Chaperones. 2024 Jun;29(3):425-436. doi: 10.1016/j.cstres.2024.04.002. Epub 2024 Apr 10. PMID: 38608858; PMCID: PMC11061232. 2: Weng W, Deng Y, Deviatiiarov R, Hamidi S, Kajikawa E, Gusev O, Kiyonari H, Zhang G, Sheng G. ETV2 induces endothelial, but not hematopoietic, lineage specification in birds. Life Sci Alliance. 2024 Apr 3;7(6):e202402694. doi: 10.26508/lsa.202402694. PMID: 38570190; PMCID: PMC10992995. 3: Xie M, Kaiser M, Gershtein Y, Schnyder D, Deviatiiarov R, Gazizova G, Shagimardanova E, Zikmund T, Kerckhofs G, Ivashkin E, Batkovskyte D, Newton PT, Andersson O, Fried K, Gusev O, Zeberg H, Kaiser J, Adameyko I, Chagin AS. The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling. Nat Commun. 2024 Mar 26;15(1):2367. doi: 10.1038/s41467-024-46030-3. PMID: 38531868; PMCID: PMC10965948. 4: Warashina T, Sato A, Hinai H, Shaikhutdinov N, Shagimardanova E, Mori H, Tamaki S, Saito M, Sanada Y, Sasaki Y, Shimada K, Dotsuta Y, Kitagaki T, Maruyama S, Gusev O, Narumi I, Kurokawa K, Morita T, Ebisuzaki T, Nishimura A, Koma Y, Kanai A. Microbiome analysis of the restricted bacteria in radioactive element-containing water at the Fukushima Daiichi Nuclear Power Station. Appl Environ Microbiol. 2024 Apr 17;90(4):e0211323. doi: 10.1128/aem.02113-23. Epub 2024 Mar 12. PMID: 38470121; PMCID: PMC11022576. 5: Intarapat S, Sukparangsi W, Gusev O, Sheng G. A Bird's-Eye View of Endangered Species Conservation: Avian Genomics and Stem Cell Approaches for Green Peafowl (Pavo muticus). Genes (Basel). 2023 Nov 4;14(11):2040. doi: 10.3390/genes14112040. PMID: 38002983; PMCID: PMC10671381. 6: Deviatiiarov R, Nagai H, Ismagulov G, Stupina A, Wada K, Ide S, Toji N, Zhang H, Sukparangsi W, Intarapat S, Gusev O, Sheng G. Dosage compensation of Z sex chromosome genes in avian fibroblast cells. Genome Biol. 2023 Sep 20;24(1):213. doi: 10.1186/s13059-023-03055-z. PMID: 37730643; PMCID: PMC10510239. 7: Niskanen JE, Ohlsson Å, Ljungvall I, Drögemüller M, Ernst RF, Dooijes D, van Deutekom HWM, van Tintelen JP, Snijders Blok CJB, van Vugt M, van Setten J, Asselbergs FW, Petrič AD, Salonen M, Hundi S, Hörtenhuber M; DoGA consortium; Kere J, Pyle WG, Donner J, Postma AV, Leeb T, Andersson G, Hytönen MK, Häggström J, Wiberg M, Friederich J, Eberhard J, Harakalova M, van Steenbeek FG, Wess G, Lohi H. Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human. Genome Med. 2023 Sep 18;15(1):73. doi: 10.1186/s13073-023-01221-3. PMID: 37723491; PMCID: PMC10506233. 8: Shaikhutdinov NM, Klink GV, Garushyants SK, Kozlova OS, Cherkasov AV, Kikawada T, Okuda T, Pemba D, Shagimardanova EI, Penin AA, Deviatiiarov RM, Gazizova GR, Cornette R, Gusev OA, Bazykin GA. Population Genomics of Two Closely Related Anhydrobiotic Midges Reveals Differences in Adaptation to Extreme Desiccation. Genome Biol Evol. 2023 Oct 6;15(10):evad169. doi: 10.1093/gbe/evad169. PMID: 37708413; PMCID: PMC10558213. 9: Petersen J, Englmaier L, Artemov AV, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov EE, Pajuelo Reguera D, Zeberg H, Kaucka M, Kastriti ME, Krivanek J, Radaszkiewicz T, Gömöryová K, Knauth S, Potesil D, Zdrahal Z, Ganji RS, Grabowski A, Buhl ME, Zikmund T, Kavkova M, Axelson H, Lindgren D, Kramann R, Kuppe C, Erdélyi F, Máté Z, Szabó G, Koehne T, Harkany T, Fried K, Kaiser J, Boor P, Fekete C, Rozman J, Kasparek P, Prochazka J, Sedlacek R, Bryja V, Gusev O, Adameyko I. A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology. Nat Commun. 2023 May 29;14(1):3092. doi: 10.1038/s41467-023-38663-7. Erratum in: Nat Commun. 2023 Jun 15;14(1):3565. doi: 10.1038/s41467-023-39373-w. PMID: 37248239; PMCID: PMC10226981. 10: Deviatiiarov RM, Gams A, Kulakovskiy IV, Buyan A, Meshcheryakov G, Syunyaev R, Singh R, Shah P, Tatarinova TV, Gusev O, Efimov IR. An atlas of transcribed human cardiac promoters and enhancers reveals an important role of regulatory elements in heart failure. Nat Cardiovasc Res. 2023 Jan;2(1):58-75. doi: 10.1038/s44161-022-00182-x. Epub 2023 Jan 16. PMID: 39196209.

研究テーマ

Regulatory transcriptomics of human development and deseases

研究業績（論文）

1: Belott CJ, Gusev OA, Kikawada T, Menze MA. Membraneless and membrane-bound organelles in an anhydrobiotic cell line are protected from desiccation-induced damage. Cell Stress Chaperones. 2024 Jun;29(3):425-436. doi: 10.1016/j.cstres.2024.04.002. Epub 2024 Apr 10. PMID: 38608858; PMCID: PMC11061232.

2: Weng W, Deng Y, Deviatiiarov R, Hamidi S, Kajikawa E, Gusev O, Kiyonari H, Zhang G, Sheng G. ETV2 induces endothelial, but not hematopoietic, lineage specification in birds. Life Sci Alliance. 2024 Apr 3;7(6):e202402694. doi: 10.26508/lsa.202402694. PMID: 38570190; PMCID: PMC10992995.

3: Xie M, Kaiser M, Gershtein Y, Schnyder D, Deviatiiarov R, Gazizova G, Shagimardanova E, Zikmund T, Kerckhofs G, Ivashkin E, Batkovskyte D, Newton PT, Andersson O, Fried K, Gusev O, Zeberg H, Kaiser J, Adameyko I, Chagin AS. The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling. Nat Commun. 2024 Mar 26;15(1):2367. doi: 10.1038/s41467-024-46030-3. PMID: 38531868; PMCID: PMC10965948.

4: Warashina T, Sato A, Hinai H, Shaikhutdinov N, Shagimardanova E, Mori H, Tamaki S, Saito M, Sanada Y, Sasaki Y, Shimada K, Dotsuta Y, Kitagaki T, Maruyama S, Gusev O, Narumi I, Kurokawa K, Morita T, Ebisuzaki T, Nishimura A, Koma Y, Kanai A. Microbiome analysis of the restricted bacteria in radioactive element-containing water at the Fukushima Daiichi Nuclear Power Station. Appl Environ Microbiol. 2024 Apr 17;90(4):e0211323. doi: 10.1128/aem.02113-23. Epub 2024 Mar 12. PMID: 38470121; PMCID: PMC11022576.

5: Intarapat S, Sukparangsi W, Gusev O, Sheng G. A Bird's-Eye View of Endangered Species Conservation: Avian Genomics and Stem Cell Approaches for Green Peafowl (Pavo muticus). Genes (Basel). 2023 Nov 4;14(11):2040. doi: 10.3390/genes14112040. PMID: 38002983; PMCID: PMC10671381.

6: Deviatiiarov R, Nagai H, Ismagulov G, Stupina A, Wada K, Ide S, Toji N, Zhang H, Sukparangsi W, Intarapat S, Gusev O, Sheng G. Dosage compensation of Z sex chromosome genes in avian fibroblast cells. Genome Biol. 2023 Sep 20;24(1):213. doi: 10.1186/s13059-023-03055-z. PMID: 37730643; PMCID: PMC10510239.

7: Niskanen JE, Ohlsson Å, Ljungvall I, Drögemüller M, Ernst RF, Dooijes D, van Deutekom HWM, van Tintelen JP, Snijders Blok CJB, van Vugt M, van Setten J, Asselbergs FW, Petrič AD, Salonen M, Hundi S, Hörtenhuber M; DoGA consortium; Kere J, Pyle WG, Donner J, Postma AV, Leeb T, Andersson G, Hytönen MK, Häggström J, Wiberg M, Friederich J, Eberhard J, Harakalova M, van Steenbeek FG, Wess G, Lohi H. Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human. Genome Med. 2023 Sep 18;15(1):73. doi: 10.1186/s13073-023-01221-3. PMID: 37723491; PMCID: PMC10506233.

8: Shaikhutdinov NM, Klink GV, Garushyants SK, Kozlova OS, Cherkasov AV, Kikawada T, Okuda T, Pemba D, Shagimardanova EI, Penin AA, Deviatiiarov RM, Gazizova GR, Cornette R, Gusev OA, Bazykin GA. Population Genomics of Two Closely Related Anhydrobiotic Midges Reveals Differences in Adaptation to Extreme Desiccation. Genome Biol Evol. 2023 Oct 6;15(10):evad169. doi: 10.1093/gbe/evad169. PMID: 37708413; PMCID: PMC10558213.

9: Petersen J, Englmaier L, Artemov AV, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov EE, Pajuelo Reguera D, Zeberg H, Kaucka M, Kastriti ME, Krivanek J, Radaszkiewicz T, Gömöryová K, Knauth S, Potesil D, Zdrahal Z, Ganji RS, Grabowski A, Buhl ME, Zikmund T, Kavkova M, Axelson H, Lindgren D, Kramann R, Kuppe C, Erdélyi F, Máté Z, Szabó G, Koehne T, Harkany T, Fried K, Kaiser J, Boor P, Fekete C, Rozman J, Kasparek P, Prochazka J, Sedlacek R, Bryja V, Gusev O, Adameyko I. A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology. Nat Commun. 2023 May 29;14(1):3092. doi: 10.1038/s41467-023-38663-7. Erratum in: Nat Commun. 2023 Jun 15;14(1):3565. doi: 10.1038/s41467-023-39373-w. PMID: 37248239; PMCID: PMC10226981.

10: Deviatiiarov RM, Gams A, Kulakovskiy IV, Buyan A, Meshcheryakov G, Syunyaev R, Singh R, Shah P, Tatarinova TV, Gusev O, Efimov IR. An atlas of transcribed human cardiac promoters and enhancers reveals an important role of regulatory elements in heart failure. Nat Cardiovasc Res. 2023 Jan;2(1):58-75. doi: 10.1038/s44161-022-00182-x. Epub 2023 Jan 16. PMID: 39196209.

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【学校法人順天堂】研究者情報データベース

研究業績詳細

GUSEV OLEG（グセフ オレグ）

GUSEV OLEG（グセフオレグ）