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研究業績詳細

加賀英義（カガヒデヨシ）

研究テーマ	インスリン抵抗性
研究業績（論文）	1. Abe H, Mita T, Kudo K, Funayama T, Tokoro M, Kaga H, Ikeda F, Kanazawa A, Hirose T, Kawamori R, Watada H. Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy. Endocr J. 2009;56(7):911-913. 2. Kojima Y, Kaga H, Hayashi S, Kitazawa T, Iimura Y, Ohno M, Yoshitsugu M, Fujiwara M, Hiyoshi T. Comparison between sitagliptin and nateglinide on postprandial lipid levels: The STANDARD study. World J Diabetes. 2013;4(1):8-13. 3. Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Relation Between Insulin Sensitivity and Metabolic Abnormalities in Japanese Men With BMI of 23-25 kg/m(2). J Clin Endocrinol Metab. 2016;101(10):3676-3684. 4. Funayama T, Tamura Y, Takeno K, Kawaguchi M, Kakehi S, Watanabe T, Furukawa Y, Kaga H, Yamamoto R, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Effects of alcohol abstinence on glucose metabolism in Japanese men with elevated fasting glucose: A pilot study. Sci Rep. 2017;7:40277. 5. Furukawa Y, Tamura Y, Takeno K, Funayama T, Kaga H, Suzuki R, Watanabe T, Kakehi S, Kanazawa A, Kawamori R, Watada H. Impaired peripheral insulin sensitivity in non-obese Japanese patients with type 2 diabetes mellitus and fatty liver. J Diabetes Investig. 2017. 6. Kaga H, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Kanazawa A, Kawamori R, Watada H. Correlates of insulin clearance in apparently healthy non-obese Japanese men. Sci Rep. 2017;7(1):1462. 7. Someya Y, Tamura Y, Suzuki R, Kaga H, Kadowaki S, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Takeno K, Sato J, Kanazawa A, Kawamori R, Watada H. Characteristics of Glucose Metabolism in Underweight Japanese Women. J Endocr Soc. 2018;2(3):279-289. 8. Kadowaki S, Tamura Y, Someya Y, Takeno K, Kaga H, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Kanazawa A, Kawamori R, Watada H. Fatty Liver Has Stronger Association With Insulin Resistance Than Visceral Fat Accumulation in Nonobese Japanese Men. J Endocr Soc. 2019;3(7):1409-1416. 9. Kaga H, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Suzuki R, Sugimoto D, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Kanazawa A, Kawamori R, Watada H. Higher C-Peptide Level During Glucose Clamp Is Associated With Muscle Insulin Resistance in Nonobese Japanese Men. J Endocr Soc. 2019;3(10):1847-1857. 10. Katahira T, Kanazawa A, Shinohara M, Koshibu M, Kaga H, Mita T, Tosaka Y, Komiya K, Miyatsuka T, Ikeda F, Azuma K, Takayanagi N, Ogihara T, Ohmura C, Miyachi A, Mieno E, Yamashita S, Watada H. Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry. J Endocr Soc. 2019;3(1):42-51. 11. Someya Y, Tamura Y, Kaga H, Nojiri S, Shimada K, Daida H, Ishijima M, Kaneko K, Aoki S, Miida T, Hirayama S, Konishi S, Hattori N, Motoi Y, Naito H, Kawamori R, Watada H. Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study. BMJ Open. 2019;9(9):e031584. 12. Sugimoto D, Tamura Y, Takeno K, Kaga H, Someya Y, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Kanazawa A, Kawamori R, Watada H. Clinical Features of Nonobese, Apparently Healthy, Japanese Men With Reduced Adipose Tissue Insulin Sensitivity. J Clin Endocrinol Metab. 2019;104(6):2325-2333. 13. Suzuki R, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Kaga H, Sugimoto D, Kadowaki S, Someya Y, Kanazawa A, Kawamori R, Watada H. Three days of a eucaloric, low-carbohydrate/high-fat diet increases insulin clearance in healthy non-obese Japanese men. Sci Rep. 2019;9(1):3857. 14. Hirayama S, Hori A, Isshiki M, Hirayama A, Ueno T, Tamura Y, Kaga H, Watada H, Kawamori R, Miida T. Fasting serum free glycerol concentration is a potential surrogate marker of visceral obesity and insulin sensitivity in middle-aged Japanese men. J Clin Lipidol. 2020;14(4):522-530. 15. Kaga H, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Suzuki R, Sugimoto D, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Sato H, Kawamori R, Watada H. Shape of the glucose response curve during an oral glucose tolerance test is associated with insulin clearance and muscle insulin sensitivity in healthy non-obese men. J Diabetes Investig. 2020;11(4):874-877. 16. Nakagata T, Tamura Y, Kaga H, Sato M, Yamasaki N, Someya Y, Kadowaki S, Sugimoto D, Satoh H, Kawamori R, Watada H. Ingestion of an exogenous ketone monoester improves the glycemic response during oral glucose tolerance test in individuals with impaired glucose tolerance: A cross-over randomized trial. J Diabetes Investig. 2020. 17. Sato M, Tamura Y, Someya Y, Takeno K, Kaga H, Kadowaki S, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Sato H, Kawamori R, Watada H. Characteristics associated with elevated 1-h plasma glucose levels during a 75-g oral glucose tolerance test in non-obese Japanese men. J Diabetes Investig. 2020;11(6):1520-1523. 18. Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H. Reduced muscle strength of knee extensors is a risk factor for silent lacunar infarcts among Japanese elderly people the Bunkyo Health Study. JCSM Clinical Reports. 2020;5:79-85. 19. Someya Y, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Eshima H, Watanabe K, Kurihara T, Yanagiya T, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Kawamori R, Watada H. Decreased Muscle Strength of Knee Flexors is Associated with Impaired Muscle Insulin Sensitivity in Non-Diabetic Middle-Aged Japanese Male Subjects. Diabetes Ther. 2020. 20. Yamasaki N, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Sato M, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Sato H, Kawamori R, Watada H. Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men. Sci Rep. 2020;10(1):4102. 21. Hagiwara A, Fujimoto K, Kamagata K, Murata S, Irie R, Kaga H, Someya Y, Andica C, Fujita S, Kato S, Fukunaga I, Wada A, Hori M, Tamura Y, Kawamori R, Watada H, Aoki S. Age-Related Changes in Relaxation Times, Proton Density, Myelin, and Tissue Volumes in Adult Brain Analyzed by 2-Dimensional Quantitative Synthetic Magnetic Resonance Imaging. Invest Radiol. 2021;56(3):163-172. 22. Kanazawa A, Aida M, Yoshida Y, Kaga H, Katahira T, Suzuki L, Tamaki S, Sato J, Goto H, Azuma K, Shimizu T, Takahashi T, Yamashiro Y, Watada H. Effects of Synbiotic Supplementation on Chronic Inflammation and the Gut Microbiota in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Study. Nutrients. 2021;13(2). 23. Kiya M, Tamura Y, Takeno K, Someya Y, Kakehi S, Sato M, Yamasaki N, Kadowaki S, Suzuki R, Furukawa Y, Sugimoto D, Kaga H, Funayama T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Satoh H, Kawamori R, Watada H. Adipose Insulin Resistance and Decreased Adiponectin Are Correlated With Metabolic Abnormalities in Nonobese Men. J Clin Endocrinol Metab. 2021;106(5):e2228-e2238. 24. Otsuka H, Tabata H, Shi H, Kaga H, Someya Y, Abulaiti A, Naito H, Umemura F, Kakehi S, Ishijima M, Kawamori R, Watada H, Tamura Y. Associations of Exercise Habits in Adolescence and Old Age with Risk of Osteoporosis in Older Adults: The Bunkyo Health Study. J Clin Med. 2021;10(24). 25. Sato M, Tamura Y, Kaga H, Yamasaki N, Kiya M, Kadowaki S, Sugimoto D, Funayama T, Someya Y, Kakehi S, Nojiri S, Satoh H, Kawamori R, Watada H. Short-Term SGLT2 Inhibitor Administration Does Not Alter Systemic Insulin Clearance in Type 2 Diabetes. Biomedicines. 2021;9(9). 26. Sato M, Tamura Y, Nakagata T, Someya Y, Kaga H, Yamasaki N, Kiya M, Kadowaki S, Sugimoto D, Satoh H, Kawamori R, Watada H. Prevalence and Features of Impaired Glucose Tolerance in Young Underweight Japanese Women. J Clin Endocrinol Metab. 2021;106(5):e2053-e2062. 27. Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H. Insulin resistance and muscle weakness are synergistic risk factors for silent lacunar infarcts: the Bunkyo Health Study. Sci Rep. 2021;11(1):21093. 28. Takeno K, Tamura Y, Kakehi S, Kaga H, Kawamori R, Watada H. ALDH2 rs671 Is Associated With Elevated FPG, Reduced Glucose Clearance and Hepatic Insulin Resistance in Japanese Men. J Clin Endocrinol Metab. 2021;106(9):e3573-e3581. 29. Yamasaki N, Tamura Y, Kaga H, Sato M, Kiya M, Kadowaki S, Suzuki R, Furukawa Y, Sugimoto D, Funayama T, Someya Y, Kakehi S, Nojiri S, Satoh H, Kawamori R, Watada H. A decrease in plasma glucose levels is required for increased endogenous glucose production with a single administration of a sodium-glucose co-transporter-2 inhibitor tofogliflozin. Diabetes Obes Metab. 2021;23(5):1092-1100. 30. Andica C, Kamagata K, Uchida W, Takabayashi K, Shimoji K, Kaga H, Someya Y, Tamura Y, Kawamori R, Watada H, Hori M, Aoki S. White matter fiber-specific degeneration in older adults with metabolic syndrome. Mol Metab. 2022;62:101527. 31. Kaga H, Tamura Y, Someya Y, Naito H, Tabata H, Kakehi S, Yamasaki N, Sato M, Kadowaki S, Suzuki R, Sugimoto D, Kawamori R, Watada H. Prediabetes is an independent risk factor for sarcopenia in older men, but not in older women: the Bunkyo Health Study. J Cachexia Sarcopenia Muscle. 2022;13(6):2835-2842. 32. Murata S, Hagiwara A, Kaga H, Someya Y, Nemoto K, Goto M, Kamagata K, Irie R, Hori M, Andica C, Wada A, Kumamaru KK, Shimoji K, Otsuka Y, Hoshito H, Tamura Y, Kawamori R, Watada H, Aoki S. Comparison of Brain Volume Measurements Made with 0.3- and 3-T MR Imaging. Magn Reson Med Sci. 2022;21(3):517-524. 33. Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H. Sarcopenic obesity is associated with cognitive impairment in community-dwelling older adults: The Bunkyo Health Study. Clin Nutr. 2022;41(5):1046-1051. 34. Sugimoto M, Tabata H, Kaga H, Someya Y, Kakehi S, Abudurezake A, Naito H, Ito N, Shi H, Otsuka H, Umemura F, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Association of ALDH2 Genotypes and Alcohol Intake with Dietary Patterns: The Bunkyo Health Study. Nutrients. 2022;14(22). 35. Andica C, Kamagata K, Takabayashi K, Kikuta J, Kaga H, Someya Y, Tamura Y, Kawamori R, Watada H, Taoka T, Naganawa S, Aoki S. Neuroimaging findings related to glymphatic system alterations in older adults with metabolic syndrome. Neurobiol Dis. 2023;177:105990. 36. Asano S, Ogawa A, Osada T, Oka S, Nakajima K, Oshima Y, Tanaka S, Kaga H, Tamura Y, Watada H, Kawamori R, Konishi S. Reduced gray matter volume in the default-mode network associated with insulin resistance. Cereb Cortex. 2023;33(23):11225-11234. 37. Kadowaki S, Tamura Y, Sugimoto D, Kaga H, Suzuki R, Someya Y, Yamasaki N, Sato M, Kakehi S, Kanazawa A, Kawamori R, Watada H. A Short-Term High-Fat Diet Worsens Insulin Sensitivity with Changes in Metabolic Parameters in Non-Obese Japanese Men. J Clin Med. 2023;12(12). 38. Kurita M, Satoh H, Kaga H, Kadowaki S, Someya Y, Tosaka Y, Nishida Y, Ikeda F, Tamura Y, Watada H. A 7 day inpatient diabetes education program improves quality of life and glycemic control 12 months after discharge. J Diabetes Investig. 2023;14(6):811-820. 39. Morita Y, Kamagata K, Andica C, Takabayashi K, Kikuta J, Fujita S, Samoyeau T, Uchida W, Saito Y, Tabata H, Naito H, Someya Y, Kaga H, Tamura Y, Miyata M, Akashi T, Wada A, Taoka T, Naganawa S, Watada H, Kawamori R, Abe O, Aoki S. Glymphatic system impairment in nonathlete older male adults who played contact sports in their youth associated with cognitive decline: A diffusion tensor image analysis along the perivascular space study. Front Neurol. 2023;14:1100736. 40. Murofushi Y, Yamaguchi S, Kadoya H, Otsuka H, Ogura K, Kaga H, Yoshizawa Y, Tamura Y. Multidimensional background examination of young underweight Japanese women: focusing on their dieting experiences. Front Public Health. 2023;11:1130252. 41. Otsuka H, Tabata H, Shi H, Sugimoto M, Kaga H, Someya Y, Naito H, Ito N, Abudurezake A, Umemura F, Tajima T, Kakehi S, Yoshizawa Y, Ishijima M, Kawamori R, Watada H, Tamura Y. Playing basketball and volleyball during adolescence is associated with higher bone mineral density in old age: the Bunkyo Health Study. Front Physiol. 2023;14:1227639. 42. Tabata H, Otsuka H, Shi H, Sugimoto M, Kaga H, Someya Y, Naito H, Ito N, Abudurezake A, Umemura F, Kiya M, Tajima T, Kakehi S, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Effects of exercise habits in adolescence and older age on sarcopenia risk in older adults: the Bunkyo Health Study. J Cachexia Sarcopenia Muscle. 2023;14(3):1299-1311. 43. Tamura Y, Kaga H, Abe Y, Yoshii H, Seino H, Hiyoshi T, Kuribayashi N, Inoue I, Watada H. Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). Nutrients. 2023;15(13). 44. Andica C, Kamagata K, Takabayashi K, Mahemuti Z, Iwasaki M, Hagiwara A, Uchida W, Tabata H, Naito H, Kaga H, Someya Y, Tamura Y, Kawamori R, Watada H, Aoki S. Myelin Changes in Poor Sleepers: Insights into Glymphatic Clearance Function and Regional Circadian Clock Gene Expression. Aging Dis. 2024;16(4):2453-2467. 45. Ito N, Kaga H, Someya Y, Naito H, Tabata H, Kakehi S, Tajima T, Yamasaki N, Sato M, Kadowaki S, Sugimoto D, Nishida Y, Kawamori R, Watada H, Tamura Y. Obesity with low bone mineral density is a risk for cerebral small-vessel disease in older adults: The Bunkyo Health Study. Obes Res Clin Pract. 2024;18(5):363-370. 46. Ito S, Takuwa H, Kakehi S, Someya Y, Kaga H, Kumahashi N, Kuwata S, Wakatsuki T, Kadowaki M, Yamamoto S, Abe T, Takeda M, Ishikawa Y, Liu X, Otomo N, Suetsugu H, Koike Y, Hikino K, Tomizuka K, Momozawa Y, Ozaki K, Isomura M, Nabika T, Kaneko H, Ishijima M, Kawamori R, Watada H, Tamura Y, Uchio Y, Ikegawa S, Terao C. A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals. Commun Biol. 2024;7(1):513. 47. Kikuta J, Kamagata K, Takabayashi K, Hayakawa Y, Taoka T, Saito Y, Uchida W, Guo S, Yoshida S, Yamazaki K, Wada A, Kaga H, Tamura Y, Kawamori R, Watada H, Aoki S. Decreased Water Diffusivity Along the Perivascular Space in Older Adults With Poor Sleep Quality. J Neurosci Res. 2024;102(12):e70005. 48. Muroga Y, Kaga H, Bui TH, Sugimoto M, Someya Y, Kakehi S, Tabata H, Naito H, Abudurezake A, Shi H, Otsuka H, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Dietary characteristics of urban community-dwelling older adults with low muscle mass: the bunkyo health study: a cross-sectional study. BMC Geriatr. 2024;24(1):614. 49. Naito H, Kaga H, Someya Y, Tabata H, Kakehi S, Tajima T, Ito N, Yamasaki N, Sato M, Kadowaki S, Sugimoto D, Nishida Y, Kawamori R, Watada H, Tamura Y. Fat Accumulation and Elevated Free Fatty Acid Are Associated With Age-Related Glucose Intolerance: Bunkyo Health Study. J Endocr Soc. 2024;8(2):bvad164. 50. Otsuka H, Tabata H, Shi H, Sugimoto M, Kaga H, Someya Y, Naito H, Ito N, Abudurezake A, Umemura F, Tajima T, Kakehi S, Yoshizawa Y, Ishijima M, Kawamori R, Watada H, Tamura Y. Corrigendum: Playing basketball and volleyball during adolescence is associated with higher bone mineral density in old age: the Bunkyo Health Study. Front Physiol. 2024;15:1385648. 51. Sakamoto S, Kakehi S, Abudurezake A, Kaga H, Someya Y, Tabata H, Yoshizawa Y, Naito H, Tajima T, Ito N, Kawamori R, Watada H, Tamura Y. Sex-specific impact of GCKR rs1260326 polymorphism on metabolic traits in an older Japanese population: the Bunkyo Health Study. Ther Adv Endocrinol Metab. 2024;15:20420188241280540. 52. Sato M, Tamura Y, Kaga H, Yamasaki N, Kadowaki S, Sugimoto D, Nakagata T, Someya Y, Nishida Y, Kawamori R, Watada H. Adipose tissue insulin resistance in young Japanese women is associated with metabolic abnormalities and dehydroepiandrosterone-sulfate. Front Endocrinol (Lausanne). 2024;15:1390778. 53. Shi H, Tabata H, Otsuka H, Iwashimizu T, Kaga H, Someya Y, Abudurezake A, Kakehi S, Naito H, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Association between exercise habits in adolescence and old age and the risk of mild cognitive impairment: the Bunkyo health study. Front Aging Neurosci. 2024;16:1456665. 54. Shi H, Tabata H, Otsuka H, Kaga H, Someya Y, Abudurezake A, Kakehi S, Naito H, Ito N, Tajima T, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Exercise habits in adolescence and old age are positively associated with geriatric depressive symptoms: the Bunkyo Health Study. Front Public Health. 2024;12:1405666. 55. Tajima T, Kaga H, Ito N, Kogai T, Naito H, Kakehi S, Kadowaki S, Nishida Y, Kawamori R, Tamura Y, Watada H. Rationale and Design of the Study to Investigate the Metabolic Action of Imeglimin on Patients with Type 2 Diabetes Mellitus (SISIMAI). Diabetes Ther. 2024;15(12):2569-2580. 56. Tajima T, Kaga H, Someya Y, Tabata H, Naito H, Kakehi S, Ito N, Yamasaki N, Sato M, Kadowaki S, Sugimoto D, Nishida Y, Kawamori R, Watada H, Tamura Y. Low Handgrip Strength (Possible Sarcopenia) With Insulin Resistance Is Associated With Type 2 Diabetes Mellitus. J Endocr Soc. 2024;8(3):bvae016. 57. Tuerxun R, Kamagata K, Saito Y, Andica C, Takabayashi K, Uchida W, Yoshida S, Kikuta J, Tabata H, Naito H, Someya Y, Kaga H, Miyata M, Akashi T, Wada A, Taoka T, Naganawa S, Tamura Y, Watada H, Kawamori R, Aoki S. Assessing interstitial fluid dynamics in type 2 diabetes mellitus and prediabetes cases through diffusion tensor imaging analysis along the perivascular space. Front Aging Neurosci. 2024;16:1362457. 58. Abudurezake A, Kakehi S, Umemura F, Kaga H, Someya Y, Tabata H, Yoshizawa Y, Naito H, Tajima T, Ito N, Otsuka H, Shi H, Sugimoto M, Sakamoto S, Muroga Y, Wakabayashi H, Kawamori R, Watada H, Tamura Y. Masseter Muscle Volume, Sarcopenia, and Muscle Determinants: Insights from ACTN3 Polymorphism in Elderly Japanese in the Bunkyo Health Study. Arch Med Res. 2025;56(1):103095. 59. Asano S, Ogawa A, Osada T, Oka S, Nakajima K, Oshima Y, Tanaka S, Kaga H, Tamura Y, Watada H, Kawamori R, Konishi S. Insulin Resistance-related Gray Matter Volume Reduction is Associated with the Default Mode Network. Juntendo Med J. 2025;71(1):32-35. 60. Bui TH, Kaga H, Kakehi S, Someya Y, Tabata H, Yoshizawa Y, Naito H, Tajima T, Ito N, Kadowaki S, Nishida Y, Kawamori R, Watada H, Tamura Y. Factors Associated With Type 2 Diabetes in Older Japanese With Similar Genetic Risk Scores: The Bunkyo Health Study. J Endocr Soc. 2025;9(2):bvaf019. 61. Kamio S, Hagiwara A, Kamagata K, Uchida W, Nakaya M, Sekine T, Hara N, Tsukamoto Y, Akashi T, Wada A, Naito H, Tabata H, Kaga H, Tamura Y, Kawamori R, Watada H, Abe O, Aoki S. Association between cognitive function and relaxation rates of the cerebral cortex. J Neurol Sci. 2025;472:123466. 62. Otsuka H, Tabata H, Ito N, Shi H, Iwashimizu T, Kaga H, Someya Y, Naito H, Abudurezake A, Kakehi S, Yoshizawa Y, Ishijima M, Kawamori R, Watada H, Tamura Y. Age-related differences in bone structural parameters using 3D-DXA and TBS in men and women: The Bunkyo Health Study. Bone. 2025;199:117549.

研究テーマ

インスリン抵抗性

研究業績（論文）

1. Abe H, Mita T, Kudo K, Funayama T, Tokoro M, Kaga H, Ikeda F, Kanazawa A, Hirose T, Kawamori R, Watada H. Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy. Endocr J. 2009;56(7):911-913.
2. Kojima Y, Kaga H, Hayashi S, Kitazawa T, Iimura Y, Ohno M, Yoshitsugu M, Fujiwara M, Hiyoshi T. Comparison between sitagliptin and nateglinide on postprandial lipid levels: The STANDARD study. World J Diabetes. 2013;4(1):8-13.
3. Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Relation Between Insulin Sensitivity and Metabolic Abnormalities in Japanese Men With BMI of 23-25 kg/m(2). J Clin Endocrinol Metab. 2016;101(10):3676-3684.
4. Funayama T, Tamura Y, Takeno K, Kawaguchi M, Kakehi S, Watanabe T, Furukawa Y, Kaga H, Yamamoto R, Kanazawa A, Fujitani Y, Kawamori R, Watada H. Effects of alcohol abstinence on glucose metabolism in Japanese men with elevated fasting glucose: A pilot study. Sci Rep. 2017;7:40277.
5. Furukawa Y, Tamura Y, Takeno K, Funayama T, Kaga H, Suzuki R, Watanabe T, Kakehi S, Kanazawa A, Kawamori R, Watada H. Impaired peripheral insulin sensitivity in non-obese Japanese patients with type 2 diabetes mellitus and fatty liver. J Diabetes Investig. 2017.
6. Kaga H, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Kanazawa A, Kawamori R, Watada H. Correlates of insulin clearance in apparently healthy non-obese Japanese men. Sci Rep. 2017;7(1):1462.
7. Someya Y, Tamura Y, Suzuki R, Kaga H, Kadowaki S, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Takeno K, Sato J, Kanazawa A, Kawamori R, Watada H. Characteristics of Glucose Metabolism in Underweight Japanese Women. J Endocr Soc. 2018;2(3):279-289.
8. Kadowaki S, Tamura Y, Someya Y, Takeno K, Kaga H, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Kanazawa A, Kawamori R, Watada H. Fatty Liver Has Stronger Association With Insulin Resistance Than Visceral Fat Accumulation in Nonobese Japanese Men. J Endocr Soc. 2019;3(7):1409-1416.
9. Kaga H, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Suzuki R, Sugimoto D, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Kanazawa A, Kawamori R, Watada H. Higher C-Peptide Level During Glucose Clamp Is Associated With Muscle Insulin Resistance in Nonobese Japanese Men. J Endocr Soc. 2019;3(10):1847-1857.
10. Katahira T, Kanazawa A, Shinohara M, Koshibu M, Kaga H, Mita T, Tosaka Y, Komiya K, Miyatsuka T, Ikeda F, Azuma K, Takayanagi N, Ogihara T, Ohmura C, Miyachi A, Mieno E, Yamashita S, Watada H. Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry. J Endocr Soc. 2019;3(1):42-51.
11. Someya Y, Tamura Y, Kaga H, Nojiri S, Shimada K, Daida H, Ishijima M, Kaneko K, Aoki S, Miida T, Hirayama S, Konishi S, Hattori N, Motoi Y, Naito H, Kawamori R, Watada H. Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study. BMJ Open. 2019;9(9):e031584.
12. Sugimoto D, Tamura Y, Takeno K, Kaga H, Someya Y, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Kanazawa A, Kawamori R, Watada H. Clinical Features of Nonobese, Apparently Healthy, Japanese Men With Reduced Adipose Tissue Insulin Sensitivity. J Clin Endocrinol Metab. 2019;104(6):2325-2333.
13. Suzuki R, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Kaga H, Sugimoto D, Kadowaki S, Someya Y, Kanazawa A, Kawamori R, Watada H. Three days of a eucaloric, low-carbohydrate/high-fat diet increases insulin clearance in healthy non-obese Japanese men. Sci Rep. 2019;9(1):3857.
14. Hirayama S, Hori A, Isshiki M, Hirayama A, Ueno T, Tamura Y, Kaga H, Watada H, Kawamori R, Miida T. Fasting serum free glycerol concentration is a potential surrogate marker of visceral obesity and insulin sensitivity in middle-aged Japanese men. J Clin Lipidol. 2020;14(4):522-530.
15. Kaga H, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Suzuki R, Sugimoto D, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Sato H, Kawamori R, Watada H. Shape of the glucose response curve during an oral glucose tolerance test is associated with insulin clearance and muscle insulin sensitivity in healthy non-obese men. J Diabetes Investig. 2020;11(4):874-877.
16. Nakagata T, Tamura Y, Kaga H, Sato M, Yamasaki N, Someya Y, Kadowaki S, Sugimoto D, Satoh H, Kawamori R, Watada H. Ingestion of an exogenous ketone monoester improves the glycemic response during oral glucose tolerance test in individuals with impaired glucose tolerance: A cross-over randomized trial. J Diabetes Investig. 2020.
17. Sato M, Tamura Y, Someya Y, Takeno K, Kaga H, Kadowaki S, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Sato H, Kawamori R, Watada H. Characteristics associated with elevated 1-h plasma glucose levels during a 75-g oral glucose tolerance test in non-obese Japanese men. J Diabetes Investig. 2020;11(6):1520-1523.
18. Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H. Reduced muscle strength of knee extensors is a risk factor for silent lacunar infarcts among Japanese elderly people the Bunkyo Health Study. JCSM Clinical Reports. 2020;5:79-85.
19. Someya Y, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Eshima H, Watanabe K, Kurihara T, Yanagiya T, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Kawamori R, Watada H. Decreased Muscle Strength of Knee Flexors is Associated with Impaired Muscle Insulin Sensitivity in Non-Diabetic Middle-Aged Japanese Male Subjects. Diabetes Ther. 2020.
20. Yamasaki N, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Sato M, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Sato H, Kawamori R, Watada H. Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men. Sci Rep. 2020;10(1):4102.
21. Hagiwara A, Fujimoto K, Kamagata K, Murata S, Irie R, Kaga H, Someya Y, Andica C, Fujita S, Kato S, Fukunaga I, Wada A, Hori M, Tamura Y, Kawamori R, Watada H, Aoki S. Age-Related Changes in Relaxation Times, Proton Density, Myelin, and Tissue Volumes in Adult Brain Analyzed by 2-Dimensional Quantitative Synthetic Magnetic Resonance Imaging. Invest Radiol. 2021;56(3):163-172.
22. Kanazawa A, Aida M, Yoshida Y, Kaga H, Katahira T, Suzuki L, Tamaki S, Sato J, Goto H, Azuma K, Shimizu T, Takahashi T, Yamashiro Y, Watada H. Effects of Synbiotic Supplementation on Chronic Inflammation and the Gut Microbiota in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Study. Nutrients. 2021;13(2).
23. Kiya M, Tamura Y, Takeno K, Someya Y, Kakehi S, Sato M, Yamasaki N, Kadowaki S, Suzuki R, Furukawa Y, Sugimoto D, Kaga H, Funayama T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Satoh H, Kawamori R, Watada H. Adipose Insulin Resistance and Decreased Adiponectin Are Correlated With Metabolic Abnormalities in Nonobese Men. J Clin Endocrinol Metab. 2021;106(5):e2228-e2238.
24. Otsuka H, Tabata H, Shi H, Kaga H, Someya Y, Abulaiti A, Naito H, Umemura F, Kakehi S, Ishijima M, Kawamori R, Watada H, Tamura Y. Associations of Exercise Habits in Adolescence and Old Age with Risk of Osteoporosis in Older Adults: The Bunkyo Health Study. J Clin Med. 2021;10(24).
25. Sato M, Tamura Y, Kaga H, Yamasaki N, Kiya M, Kadowaki S, Sugimoto D, Funayama T, Someya Y, Kakehi S, Nojiri S, Satoh H, Kawamori R, Watada H. Short-Term SGLT2 Inhibitor Administration Does Not Alter Systemic Insulin Clearance in Type 2 Diabetes. Biomedicines. 2021;9(9).
26. Sato M, Tamura Y, Nakagata T, Someya Y, Kaga H, Yamasaki N, Kiya M, Kadowaki S, Sugimoto D, Satoh H, Kawamori R, Watada H. Prevalence and Features of Impaired Glucose Tolerance in Young Underweight Japanese Women. J Clin Endocrinol Metab. 2021;106(5):e2053-e2062.
27. Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H. Insulin resistance and muscle weakness are synergistic risk factors for silent lacunar infarcts: the Bunkyo Health Study. Sci Rep. 2021;11(1):21093.
28. Takeno K, Tamura Y, Kakehi S, Kaga H, Kawamori R, Watada H. ALDH2 rs671 Is Associated With Elevated FPG, Reduced Glucose Clearance and Hepatic Insulin Resistance in Japanese Men. J Clin Endocrinol Metab. 2021;106(9):e3573-e3581.
29. Yamasaki N, Tamura Y, Kaga H, Sato M, Kiya M, Kadowaki S, Suzuki R, Furukawa Y, Sugimoto D, Funayama T, Someya Y, Kakehi S, Nojiri S, Satoh H, Kawamori R, Watada H. A decrease in plasma glucose levels is required for increased endogenous glucose production with a single administration of a sodium-glucose co-transporter-2 inhibitor tofogliflozin. Diabetes Obes Metab. 2021;23(5):1092-1100.
30. Andica C, Kamagata K, Uchida W, Takabayashi K, Shimoji K, Kaga H, Someya Y, Tamura Y, Kawamori R, Watada H, Hori M, Aoki S. White matter fiber-specific degeneration in older adults with metabolic syndrome. Mol Metab. 2022;62:101527.
31. Kaga H, Tamura Y, Someya Y, Naito H, Tabata H, Kakehi S, Yamasaki N, Sato M, Kadowaki S, Suzuki R, Sugimoto D, Kawamori R, Watada H. Prediabetes is an independent risk factor for sarcopenia in older men, but not in older women: the Bunkyo Health Study. J Cachexia Sarcopenia Muscle. 2022;13(6):2835-2842.
32. Murata S, Hagiwara A, Kaga H, Someya Y, Nemoto K, Goto M, Kamagata K, Irie R, Hori M, Andica C, Wada A, Kumamaru KK, Shimoji K, Otsuka Y, Hoshito H, Tamura Y, Kawamori R, Watada H, Aoki S. Comparison of Brain Volume Measurements Made with 0.3- and 3-T MR Imaging. Magn Reson Med Sci. 2022;21(3):517-524.
33. Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H. Sarcopenic obesity is associated with cognitive impairment in community-dwelling older adults: The Bunkyo Health Study. Clin Nutr. 2022;41(5):1046-1051.
34. Sugimoto M, Tabata H, Kaga H, Someya Y, Kakehi S, Abudurezake A, Naito H, Ito N, Shi H, Otsuka H, Umemura F, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Association of ALDH2 Genotypes and Alcohol Intake with Dietary Patterns: The Bunkyo Health Study. Nutrients. 2022;14(22).
35. Andica C, Kamagata K, Takabayashi K, Kikuta J, Kaga H, Someya Y, Tamura Y, Kawamori R, Watada H, Taoka T, Naganawa S, Aoki S. Neuroimaging findings related to glymphatic system alterations in older adults with metabolic syndrome. Neurobiol Dis. 2023;177:105990.
36. Asano S, Ogawa A, Osada T, Oka S, Nakajima K, Oshima Y, Tanaka S, Kaga H, Tamura Y, Watada H, Kawamori R, Konishi S. Reduced gray matter volume in the default-mode network associated with insulin resistance. Cereb Cortex. 2023;33(23):11225-11234.
37. Kadowaki S, Tamura Y, Sugimoto D, Kaga H, Suzuki R, Someya Y, Yamasaki N, Sato M, Kakehi S, Kanazawa A, Kawamori R, Watada H. A Short-Term High-Fat Diet Worsens Insulin Sensitivity with Changes in Metabolic Parameters in Non-Obese Japanese Men. J Clin Med. 2023;12(12).
38. Kurita M, Satoh H, Kaga H, Kadowaki S, Someya Y, Tosaka Y, Nishida Y, Ikeda F, Tamura Y, Watada H. A 7 day inpatient diabetes education program improves quality of life and glycemic control 12 months after discharge. J Diabetes Investig. 2023;14(6):811-820.
39. Morita Y, Kamagata K, Andica C, Takabayashi K, Kikuta J, Fujita S, Samoyeau T, Uchida W, Saito Y, Tabata H, Naito H, Someya Y, Kaga H, Tamura Y, Miyata M, Akashi T, Wada A, Taoka T, Naganawa S, Watada H, Kawamori R, Abe O, Aoki S. Glymphatic system impairment in nonathlete older male adults who played contact sports in their youth associated with cognitive decline: A diffusion tensor image analysis along the perivascular space study. Front Neurol. 2023;14:1100736.
40. Murofushi Y, Yamaguchi S, Kadoya H, Otsuka H, Ogura K, Kaga H, Yoshizawa Y, Tamura Y. Multidimensional background examination of young underweight Japanese women: focusing on their dieting experiences. Front Public Health. 2023;11:1130252.
41. Otsuka H, Tabata H, Shi H, Sugimoto M, Kaga H, Someya Y, Naito H, Ito N, Abudurezake A, Umemura F, Tajima T, Kakehi S, Yoshizawa Y, Ishijima M, Kawamori R, Watada H, Tamura Y. Playing basketball and volleyball during adolescence is associated with higher bone mineral density in old age: the Bunkyo Health Study. Front Physiol. 2023;14:1227639.
42. Tabata H, Otsuka H, Shi H, Sugimoto M, Kaga H, Someya Y, Naito H, Ito N, Abudurezake A, Umemura F, Kiya M, Tajima T, Kakehi S, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Effects of exercise habits in adolescence and older age on sarcopenia risk in older adults: the Bunkyo Health Study. J Cachexia Sarcopenia Muscle. 2023;14(3):1299-1311.
43. Tamura Y, Kaga H, Abe Y, Yoshii H, Seino H, Hiyoshi T, Kuribayashi N, Inoue I, Watada H. Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). Nutrients. 2023;15(13).
44. Andica C, Kamagata K, Takabayashi K, Mahemuti Z, Iwasaki M, Hagiwara A, Uchida W, Tabata H, Naito H, Kaga H, Someya Y, Tamura Y, Kawamori R, Watada H, Aoki S. Myelin Changes in Poor Sleepers: Insights into Glymphatic Clearance Function and Regional Circadian Clock Gene Expression. Aging Dis. 2024;16(4):2453-2467.
45. Ito N, Kaga H, Someya Y, Naito H, Tabata H, Kakehi S, Tajima T, Yamasaki N, Sato M, Kadowaki S, Sugimoto D, Nishida Y, Kawamori R, Watada H, Tamura Y. Obesity with low bone mineral density is a risk for cerebral small-vessel disease in older adults: The Bunkyo Health Study. Obes Res Clin Pract. 2024;18(5):363-370.
46. Ito S, Takuwa H, Kakehi S, Someya Y, Kaga H, Kumahashi N, Kuwata S, Wakatsuki T, Kadowaki M, Yamamoto S, Abe T, Takeda M, Ishikawa Y, Liu X, Otomo N, Suetsugu H, Koike Y, Hikino K, Tomizuka K, Momozawa Y, Ozaki K, Isomura M, Nabika T, Kaneko H, Ishijima M, Kawamori R, Watada H, Tamura Y, Uchio Y, Ikegawa S, Terao C. A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals. Commun Biol. 2024;7(1):513.
47. Kikuta J, Kamagata K, Takabayashi K, Hayakawa Y, Taoka T, Saito Y, Uchida W, Guo S, Yoshida S, Yamazaki K, Wada A, Kaga H, Tamura Y, Kawamori R, Watada H, Aoki S. Decreased Water Diffusivity Along the Perivascular Space in Older Adults With Poor Sleep Quality. J Neurosci Res. 2024;102(12):e70005.
48. Muroga Y, Kaga H, Bui TH, Sugimoto M, Someya Y, Kakehi S, Tabata H, Naito H, Abudurezake A, Shi H, Otsuka H, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Dietary characteristics of urban community-dwelling older adults with low muscle mass: the bunkyo health study: a cross-sectional study. BMC Geriatr. 2024;24(1):614.
49. Naito H, Kaga H, Someya Y, Tabata H, Kakehi S, Tajima T, Ito N, Yamasaki N, Sato M, Kadowaki S, Sugimoto D, Nishida Y, Kawamori R, Watada H, Tamura Y. Fat Accumulation and Elevated Free Fatty Acid Are Associated With Age-Related Glucose Intolerance: Bunkyo Health Study. J Endocr Soc. 2024;8(2):bvad164.
50. Otsuka H, Tabata H, Shi H, Sugimoto M, Kaga H, Someya Y, Naito H, Ito N, Abudurezake A, Umemura F, Tajima T, Kakehi S, Yoshizawa Y, Ishijima M, Kawamori R, Watada H, Tamura Y. Corrigendum: Playing basketball and volleyball during adolescence is associated with higher bone mineral density in old age: the Bunkyo Health Study. Front Physiol. 2024;15:1385648.
51. Sakamoto S, Kakehi S, Abudurezake A, Kaga H, Someya Y, Tabata H, Yoshizawa Y, Naito H, Tajima T, Ito N, Kawamori R, Watada H, Tamura Y. Sex-specific impact of GCKR rs1260326 polymorphism on metabolic traits in an older Japanese population: the Bunkyo Health Study. Ther Adv Endocrinol Metab. 2024;15:20420188241280540.
52. Sato M, Tamura Y, Kaga H, Yamasaki N, Kadowaki S, Sugimoto D, Nakagata T, Someya Y, Nishida Y, Kawamori R, Watada H. Adipose tissue insulin resistance in young Japanese women is associated with metabolic abnormalities and dehydroepiandrosterone-sulfate. Front Endocrinol (Lausanne). 2024;15:1390778.
53. Shi H, Tabata H, Otsuka H, Iwashimizu T, Kaga H, Someya Y, Abudurezake A, Kakehi S, Naito H, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Association between exercise habits in adolescence and old age and the risk of mild cognitive impairment: the Bunkyo health study. Front Aging Neurosci. 2024;16:1456665.
54. Shi H, Tabata H, Otsuka H, Kaga H, Someya Y, Abudurezake A, Kakehi S, Naito H, Ito N, Tajima T, Yoshizawa Y, Kawamori R, Watada H, Tamura Y. Exercise habits in adolescence and old age are positively associated with geriatric depressive symptoms: the Bunkyo Health Study. Front Public Health. 2024;12:1405666.
55. Tajima T, Kaga H, Ito N, Kogai T, Naito H, Kakehi S, Kadowaki S, Nishida Y, Kawamori R, Tamura Y, Watada H. Rationale and Design of the Study to Investigate the Metabolic Action of Imeglimin on Patients with Type 2 Diabetes Mellitus (SISIMAI). Diabetes Ther. 2024;15(12):2569-2580.
56. Tajima T, Kaga H, Someya Y, Tabata H, Naito H, Kakehi S, Ito N, Yamasaki N, Sato M, Kadowaki S, Sugimoto D, Nishida Y, Kawamori R, Watada H, Tamura Y. Low Handgrip Strength (Possible Sarcopenia) With Insulin Resistance Is Associated With Type 2 Diabetes Mellitus. J Endocr Soc. 2024;8(3):bvae016.
57. Tuerxun R, Kamagata K, Saito Y, Andica C, Takabayashi K, Uchida W, Yoshida S, Kikuta J, Tabata H, Naito H, Someya Y, Kaga H, Miyata M, Akashi T, Wada A, Taoka T, Naganawa S, Tamura Y, Watada H, Kawamori R, Aoki S. Assessing interstitial fluid dynamics in type 2 diabetes mellitus and prediabetes cases through diffusion tensor imaging analysis along the perivascular space. Front Aging Neurosci. 2024;16:1362457.
58. Abudurezake A, Kakehi S, Umemura F, Kaga H, Someya Y, Tabata H, Yoshizawa Y, Naito H, Tajima T, Ito N, Otsuka H, Shi H, Sugimoto M, Sakamoto S, Muroga Y, Wakabayashi H, Kawamori R, Watada H, Tamura Y. Masseter Muscle Volume, Sarcopenia, and Muscle Determinants: Insights from ACTN3 Polymorphism in Elderly Japanese in the Bunkyo Health Study. Arch Med Res. 2025;56(1):103095.
59. Asano S, Ogawa A, Osada T, Oka S, Nakajima K, Oshima Y, Tanaka S, Kaga H, Tamura Y, Watada H, Kawamori R, Konishi S. Insulin Resistance-related Gray Matter Volume Reduction is Associated with the Default Mode Network. Juntendo Med J. 2025;71(1):32-35.
60. Bui TH, Kaga H, Kakehi S, Someya Y, Tabata H, Yoshizawa Y, Naito H, Tajima T, Ito N, Kadowaki S, Nishida Y, Kawamori R, Watada H, Tamura Y. Factors Associated With Type 2 Diabetes in Older Japanese With Similar Genetic Risk Scores: The Bunkyo Health Study. J Endocr Soc. 2025;9(2):bvaf019.
61. Kamio S, Hagiwara A, Kamagata K, Uchida W, Nakaya M, Sekine T, Hara N, Tsukamoto Y, Akashi T, Wada A, Naito H, Tabata H, Kaga H, Tamura Y, Kawamori R, Watada H, Abe O, Aoki S. Association between cognitive function and relaxation rates of the cerebral cortex. J Neurol Sci. 2025;472:123466.
62. Otsuka H, Tabata H, Ito N, Shi H, Iwashimizu T, Kaga H, Someya Y, Naito H, Abudurezake A, Kakehi S, Yoshizawa Y, Ishijima M, Kawamori R, Watada H, Tamura Y. Age-related differences in bone structural parameters using 3D-DXA and TBS in men and women: The Bunkyo Health Study. Bone. 2025;199:117549.

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加賀 英義（カガ ヒデヨシ）

加賀英義（カガヒデヨシ）