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研究業績詳細

藤原 俊之(フジワラ トシユキ)

研究テーマ 神経可塑性を誘導する新しいリハビリテーション治療
研究業績(論文) 1. Ishiwatari M, Honaga K, Tanuma A, Takakura T, Hatori K, Kurosu A, Fujiwara T. Trunk impairment as a predictor of activities of daily living in acute stroke. Front Neurol 12: 665592, 2021
2. Fujino Y, Fukata K, Inoue M, Okawa S, Okuma K, Kunieda Y, Miki H, Matsuda T, Amimoto K, Makita S, Takahashi H, Fujiwara T. Examination of rehabilitation intensity according to severity of acute stroke: A retrospective study. Journal stroke & cerebrovascular disease 30 (9): 105994, 2021
3. Morisawa T, Saitoh M, Takahashi T, Watanabe H, Mochizuki M, Kitahara E, Fujiwara T, Fujiwara K, Nishitani-Yokoyama M, Minamino T, Shimada K, Honzawa A, Shimada A, Yamamoto T, Asai T, Amano A, Daida H. Association of phase angle with hospital-acquired functional decline in older patients undergoing cardiovascular surgery. Nutrition 91-92: 111402, 2021
4. Abulimiti A, Nishitani-Yokoyama M, Shimada K, Kunimoto M, Matsubara T, Fujiwara K, Aikawa T, Ouchi S, Sugita Y, Fukano K, Kadoguchi T, Miyazaki T, Shimada A, Yamamoto T, Takahashi T, Fujiwara T, Asai T, Amano A, Daida H, Minamino T: Prognostic impact of peak oxygen uptake and heart rate reserve in patients after off pump coronary artery bypass grafting. Clin Cardiol 44: 580-587,2021
5. Takahashi T, Morisawa T, Saito M, Honzawa A, Abulimiti A, Fujiwara K, Nishitani-Yokoyama M, Shimada K, Minamino T, Fujiwara T, Daida H. Forefront of cardiac rehabilitation in Japan. Juntendo Medical Journal 67(1): 10-16, 2021
6. Kagaya H, Masakado Y, Saitoh E, Fujiwara T, Abo M, Izumi S, Nodera H, Dekundy A, Hiersemenzel R, Nalaskowski CM, Hanschmann A, Kaji R: IncobotulinumtoxinA for upper- and lower-limb spasticity in Japanese patients. Current Medical Research and Opinion : 10.10800300799520201740187, 2020.
7. Fujiwara T: Mini-review article: the role of spinal reciprocal inhibition and intracortical inhibition in functional recovery from stroke. Exp Brain Res : . 238: 1701-1705, 2020
8. Takahashi T, Morisawa T, Saitoh M, Yokoyama M, Shimada K, Fujiwara T, Daida H: Current status and future development of acute and cardiac physiotherapies in Japan. Phys Ther Res 23: 1-7, 2020.
9. A Honzawa, M Nishitani-Yokoyama, K Shimada, M Kunimoto, M Yamada, T Matsubara, R Matsumori, K Fujiwara, A Abulimiti, T Aikawa, S Ouchi, M Shimizu, Y Sugita, A Shimada, T Yamamoto, A Amano, T Asai, M Saito, T Morisawa, T Takahash, T Fujiwara, H Daida, Tohru Minamino: Relationship Between Kihon Checklist Score and Anxiety Levels in Elderly Patients Undergoing Early Phase II Cardiac Rehabilitation. Cardiol Res 11: 405-411, 2020
10. Fujii R, Sugawara H, Ishikawa M, Fujiwara T: Effects of Different Orthoses Used for Gait Training on Gait Function among Patients with Subacute Stroke. Prog Rehabil Med 5: 20200023.10249020200023, 2020.
11. Sato K, Aita N, Hokari Y, Kitahara E, Tani M, Izawa N, Hatori K, Nakamura R, Sasaki F, Sekimoto S, Jo T, Oyama G, Hatano T, Shimo Y Iwamoto H, Umemura A, Hattori N, Fujiwara T: Balance and gaot improvements of postoperative rehabilitation in patients with Parkinson's disease treated with subthalamic nucleus deep brain stimulation(STN-DBS). Parkinson's Disease : 7104071, 2019.
12. Kawakami M, Simeoni S, Tremblay S, Hannah R, Fujiwara T, Rothwell JC: Changes in the excitability of corticobulbar projections due to intraoral cooling with ice. Dysphagia : .10100700455018099754, 2019
13. Kawakami M, Okutama K, Takahashi Y, Hiramoto M, Nishimura A, Ushiba J, Fujiwara T, Liu M: Change in reciprocal inhibition of the forearm with motor imagery among patients with chronic stroke. Neural Plasticity 2018: 39463679-.10115520183946367, 2018.
14. Yamaguchi T, Fujiwara T, Lin SC, Takahashi Y, Hatori K, Liu M, Huang YZ: Priming with intermittent theta burst transcranial magnetic stimulation promotes spinal plasticity induced by peripheral patterned electrical stimulation. Frontiers in Neuroscience : 10.3389201800508, 2018.
15. Takahashi Y, Fujiwara T*, Yamaguchi T, Matsunaga H, Kawakami M, Honaga K, Mizuno K, Liu M: Voluntary contraction enhances spinal reciprocal inhibition induced by patterned electrical stimulation in patients with stroke. Restorative Neurology and Neuroscience 36: 99-105, 2018. *corresponding author
16. Mizuno K, Abe T, Ushiba J, Kawakami M, Ohwa T, Hagimura K, Ogura M, Okuyama K, Fujiwara T, Liu M: Evaluating the effectiveness and safety of the electroencephalogram-based Brain-Machine interfece rehabilitation system for patients with severe hemiparetic stroke: Protocol for a randomized controlled trial (BEST-BRAIN Trial). JMIR Res Protocol 7: 12339, 2018.
17. Nishimoto A, Kawakami M, Fujiwara T*, Hiramoto M, Honaga K, Abe K, Mizuno K, Ushiba J, Liu M: Feasibility of task-specific brain-machine interface training for upper extremity paralysis in patients with chronic hemiparetic stroke. J Rehabil Med 50: 52-58, 2018. *corresponding author
18. Okuyama K, Kawakami M, Hiramoto M, Muraoka K, Fujiwara T, Liu M: Relationships between spasticity and spinal neural circiots in patients with chronic hemiparetic stroke. Exp Brain Res 236: 207-213, 2018.
19. Kawakami M, Okutama K, Takahashi Y, Hiramoto M, Nishimura A, Ushiba J, Fujiwara T, Liu M: Change in reciprocal inhibition of the forearm with motor imagery among patients with chronic stroke. Neural Plasticity 2018:
20. Takahashi Y, Fujiwara T*, Yamaguchi T, Matsunaga H, Kawakami M, Honaga K, Mizuno K, Liu M: Voluntary contraction enhances spinal reciprocal inhibition induced by patterned electrical stimulation in patients with stroke. Restorative Neurology and Neuroscience 36: 99-105, 2018. *corresponding author
21. Takahashi Y, Fujiwara T*, Yamaguchi T, Kawakami M, Mizuno K, Liu M: The effects of patterned electrical stimulation combined with voluntary contraction on spinal reciprocal inhibition in healthy individuals. Neuroreport 28: 434-438, 2017.*corresponding author
22. Fujiwara T, Kawakami M, Honaga K, Tochikura M, Abe K. Hybrid Assistive Neuromuscular Dynamic Stimulation Therapy: A new strategy for improving upper extremity function in patients with hemiparesis following stroke. Neural Plasticity 2017: ID2350137 https://doi.org/10.1155/2017/2350137
23. Tanuma A, Fujiwara T*, Yamaguchi T, Ro T, Arano H, Uehara S, Honaga K, Mukaino M, Kimura A, Liu M. After-effects of pedaling exercise on spinal excitability and spinal reciprocal inhibition in patients with chronic stroke. Int J Neuroscience 127: 73-79, 2017. *corresponding author
24. Kodama M, Tochikura M, Shimoda N, Fujii C, Fujiwara T, Masakado Y: Premotor potential study for diagnosis of carpal tunnel syndrome. Tokai J Exp Clin Med 41: 101-107, 2016.
25. Kawakami M, Fujiwara T*, Ushiba J, Nishimoto A, Abe K, Honaga K, Nishimura A, Mizuno K, Kodama M, Masakado Y, Liu M. A new therapeutic application of brain-machine interface (BMI) training followed by hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy for patients with severe hemiparetic stroke: A proof of concept study. Restorative Neurology and Neuroscience 34: 789-797, 2016 . *corresponding author
26. Yamaguchi T, Fujiwara T*, Tsai YA, Tang SC, Kawakami M, Mizuno K, Kodama M, Masakado Y, Liu M. The effect of anodal transcranial direct current stimulation and patterned electrical stimulation on spinal inhibitory interneurons and motor function in patients with spinal cord injury. Exp Brain Res 234: 1469-1478,2016 *corresponding author
27. Fujiwara T, Honaga K, Kawakami M, Nishimoto A, Abe K, Mizuno K, Kodama M, Masakado Y, Tsuji T, Liu M: Modulation of cortical and spinal inhibition with functional recovery of upper extremity motor function among patients with chronic stroke. Restorative Neurology and Neuroscience 33: 883-894, 2015.
28. Kasashima-Shindo K, Fujiwara T*, Ushiba J, Matsushika Y, Kamatani D, Oto M, Ono T, Nishimoto A, Shindo K, Kawakami M, Tsuji T, Liu M: Brain-computer interface training combined with transcranial direct current stimulation in patients with chronic severe hemiparesis: proof of concept study. J Rehabil Med 47: 318-324,2015 *corresponding author
29. Kasuga S, Matsushika Y, Kasashima-Shindo Y, Kamatani D, Fujiwara T, Liu M, Ushiba J. Transcranial direct current stimulation enhances mu rhythm desynchronization during motor imagery that depends on handedness. Laterality : 20: 453-468,2015
30. Hayashi Y, Nagaoka M, Takagi T, Kitahara Y, Hatori K, Terakado A, Izawa N. Effectiveness of interdisciplinary team conference to manage skeletal events in rehabilitation for patients with cancer. Juntendo Medical Journal 61: 426-436, 2015
31. Uchikawa K, Inaba M, Kagami H, Ichimura S, Fujiwara T, Tsuji T, Otaka Y, Liu M: Executive dysfunction is related with decreased frontal lobe blood flow in patients with subarachnoid haemorrhage. Brain Inj 28: 15-19, 2014.
32. Ono T, Shindo K, Kawashima K, Ota N, Ito M, Ota T, Mukaino M, Fujiwara T, Kimura A, Liu M, Ushiba J: Brain-computer interface with somatosensory feedback improves functional recovery from severe hemiplegia due to chronic stroke. Front Neuroeng 7: 10.33892014000192014, 2014.
33. Mukaino M, Ono T, Shindo K, Fujiwara T, Ota T, Kimura A, Liu M, Ushiba J: Efficacy of brain-computer interface-driven neuromuscular electrical stimulation for chronic paresis after stroke. J Rehabil Med 46: 378-382, 2014.
34. Yamaguchi T, Fujiwara T*, Saito K, Tanabe S, Muraoka Y, Otaka Y, Osu R, Tsuji T, Hase K, Liu M. The effect of active pedaling combined with electrical stimulation on spinal reciprocal inhibition. J Electromyogr Kinesiol 23: 190-194, 2013. *corresponding author
35. Honaga K, Fujiwara T*, Tsuji T, Hase K, Ushiba J, Liu M. State of intracortical inhibitory interneuron activity in patients with chronic stroke. Clin Neurophysiol 124: 364-370, 2013. *corresponding author
36. Liu M, Fujiwara T, Shindo K, Kasashima Y, Otaka Y, Tsuji T, Ushiba J: Newer challenges to restore hemiparetic upper extremity after stroke: HANDS therapy and BMI neurorehabilitation. Hong Kong Physiotherapy Journal 30: 83-92, 2012.
37. Kasashima Y, Fujiwara T*, Matsushika Y, Tshuji T, Hase K, Ushiyama J, Liu M. Modulation of event related desynchronization during motor imagery with transcranial direct current stimulation (tDCS) in patients with chronic hamiparetic stroke. Exp Brain Res 221: 263-268, 2012. *corresponding author
38. Suzuki K, Fujiwara T, Tanaka N, Tsuji T, Masakado Y, Hase K, Kimura A, Liu M: Comparison of the after-effects of transcranial direct current stimulation over the motor cortex in patients with stroke and healthy volunteers. Int J Neurosci 122: 675-681, 2012
39. Osu R, Otaka Y, Ushiba J, Sakata S, Yamaguchi T, Fujiwara T, Kondo K, Liu M: A pilot study of contralateral hononymous muscle activity simulated electrical stimulation in chronic hemiplegia. Brain Inj : 26: 1105-1112, 2012.
40. Yamaguchi T, Fujiwara T*, Liu W, Liu M: Effects of pedaling exercise on the intracortical inhibition of cortical leg are. Exp Brain Res 218: 401-406, 2012. *corresponding author
41. Ushiyama J, Masakado Y, Fujiwara T, Tsuji T, Hase K, Kimura A, Liu M, Ushiba J: Contraction level-related modulation of corticamuscular coherence differs between the tibialis anterior and soleus muscles in humans. J Appl Physiology 112: 1258-1267, 2012
42. Lin HN, Nagaoka M, Hayashi Y, Hatori K. Effect of vibration stimulation on dysbasia of spastic paraplegia in neuromyelitis optica: a possible example of neuronal plasticity. BMJ Case Rep. 2012 Oct 6;2012. pii: bcr2012006793. doi: 10.1136/bcr-2012-006793
43. Tohyama T, Fujiwara T*, Matsumoto J, Honaga K, Ushiba J, Tsuji T, Hase K, Liu M: Modulation of event-related desynchronization during motor imagery with transcranial direct current stimulation in a patient with severe hemiparetic stroke: a case report. Keio J Med 60: 114-118, 2011. *corresponding author
44. Fujiwara T, Tsuji T, Honaga K, Hase K, Ushiba J, Liu M: Transcranial direct current stimulation modulates the spinal plasticity induced with patterned electrical stimulation. Clinical Neurophysiology 122: 1834-1837, 2011.
45. Nishiwaki Y, Michikawa T, Yamada M, Eto N, Takebayashi T, Kurabuchi study group: Knee pain and future self-reliance in older adults: evidence from community-based 3 year cohort study in Japan. J Epidemiol 21: 184-190, 2011.
46. Shindo K, Fujiwara T, Hara J, Oba H, Hotta F, Tsuji T, Hase K, Liu M: Effectiveness of hybrid assistive neuromuscular dynamic stimulation therapy in patients with subacute stroke: a randomized controlled pilot trial. Neurorehabiltation Neural Repair 25: 830-837, 2011.
47. Mizuno K, Tsuji T, Takebayashi T, Fujiwara T, Hase K, Liu M: Prism adaptation therapy enhances rehabilitation of stroke patients withunilateral spatial neglect: A rpndomized controlled trial.. Neurorehabilitation Neural Repair 25: 711-720, 2011
48. Osu R, Ota K, Fujiwara T, Otaka Y, Kawato M, Liu M: Quantifying the quality of hand movement in stroke patients through three dimensional curvature. Journal of NeuroEngineering and Rehabilitation 8: 62, 2011. (on line journal) doi:10.118617430003862
49. Hase K, Suzuki E, Matsumoto M, Fujiwara T, Liu M: Effects of thrapeutic gait training using a prothesis and a treadmill for ambulatory patients with hemiparesis. Arch Phys Med Rehabil 92: 1961-1966, 2011.
50. Matsumoto J, Fujiwara T*, Takahashi O, Liu M, Kimura A, Ushiba J: Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation. Journal of NeuroEngineering and Rehabilitation 7: 27, 2010. *corresponding author (peer review online journal)
51. Yagihashi T, Hatori K, Ishii K, Torii C, Momoshima S, Takahashi T, Kosaki K. Juvenile Muscular Atrophy of a Unilateral Upper Extremity (Hirayama Disease) in a Patient with CHARGE syndrome. Mol Syndromol 1: 91-94, 2010
52. Fujiwara T, Kasashima Y, Honaga K, et al. Motor improvement and corticospinal modulation induced by hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy in patients with chronic stroke. Neurorehabil Neural Repair 23: 125-132, 2009
53. Fujiwara T, Tanabe A, Uchikawa K, TsujiT, Tanuma A, Hase K, Liu M: Activities of daily living (ADL) structure of patients with Duchenne muscular dystrophy, including adults. Keio J Med 58: 223-226, 2009.
54. Hanayama K, Liu M, Higuchi Y, Fujiwara T, Tsuji T, Hase K, Ishihara T: Dysphagia in patients with Duchenne muscular dystrophy evaluated with a questionaire and videofluorography. Disabil Rehabil 30: 517-522, 2008.
55. Hase K, Fujiwara T, Tsuji T, Liu M: Effects of prothetic gait training for stroke patients to induce use of the paretic leg: a report of three cases.. Keio J Med 57: 162-167, 2008.
56. Honaga K, Masakado Y, Hirabara Y, Fujiwara T, Ota T, Kimura A, Liu M: Associated reaction and spasticity among patients with stroke. Am J Phys Med Rehabil 86: 656-661, 2007.
57. Yamada S, Liu M, Hase K, Tanaka N, Fujiwara T, Ushiba J: Development of a short version of the motor FIM for use in long-term care settings. J Rehabil Med 38: 50-56, 2006.
58. Hase K, Kamisako M, Fujiwara T, Tsuji T, Liu M: The effect of zaltoprofen on physiotherapy for limited shoulder movement in breast cancer patients: a single-blinded before-after trial. Arch Phys Med Rehabil 87: 1618-1622, 2006.
59. Matsunaga K, Maruyama A, Fujiwara T, Nakanishi R, Tsuji S, Rothwell JC: Increased corticospinal excitability after 5 Hz rTMS over the human supplementary motor area.. J Physiol 562: 295-306, 2005.
60. Fujiwara T, Liu M, Tanuma A, Hase K, Tsuji T: Pedaling exercise for neuromuscular re-education: a review. Crit Rev Phys Rehabil Med 17: 163-178, 2005.
61. Nishiwaki K, Tsuji T, Liu M, Hase K, Tanaka N, Fujiwara T: Identification of a simple screening tool for dysphagia in patients with stroke using factor analysis of multiple dysphagia variables. J Rehabil Med 37: 247-251, 2005.
62. Liu M, Hase K, Tsuji T, Fujiwara T, Yamada S, Masakado Y, Kimura A: Clinical electromyography and electrodiagnosis course at Keio University Hospital--a 7-year experience. Keio J Med 54: 193-196, 2005.
63. Uchikawa K, Liu M, Hanayama K, Tsuji T, Fujiwara T, Chino N: Functional status and muscle strength in people with Duchenne muscular dystrophy living in the community. J Rehabil Med 36: 124-129, 2004.
64. Fujiwara T, Rothwell JC: The after effects of motor cortex rTMS depend on the state of contraction when rTMS is applied. Clin Neurophysiol 115: 1514-1518, 2004.
65. Fujiwara T, Liu M, Tsuji T, Sonoda S, Mizuno K, Akaboshi K, Hase K, Masakado Y, Chino N: Development of a New Measure to Assess Trunk Impairment after Stroke (The Trunk Impairment Scale): Its Psychometric Properties. Am J Phys Med Rehabil 83: 681-688, 2004.
66. Fujiwara T, Liu M, Hase K, Tanaka N, Hara Y: Electrophysiological and clinical assessment of a simple wrist-hand splint for patients with chronic spastic hemiparesis secondary to stroke. Electromyogr clin Neurophysiol 44: 423-429, 2004.
67. Fujiwara T, Liu M, Chino N: The effect of pedaling exercise on hemiplegic lower limb. Am J Phys Med Rehabil 82: 357-363, 2003.
68. Liu M, Mineo K, Hanayama K, Fujiwara T, Chino N: Practical problems and management of seating through the clinical stages of Duchenne's muscular dystrophy. Arch Phys Med Rehabil 84: 818-824, 2003.
69. Liu M, Tsuji T, Hase K, Hara Y, Fujiwara T: Physical fitness in persons with hemiparetic stroke. Keio J Med 52: 211-219, 2003.
70. Fujiwara T, Liu M, Arita M, Chino N: Electrophysiological assessment of wrist orthosis. Clin Neurophysiol 113: 975, 2002.
71. Fujiwara T, Sonoda S, Okajima Y, Chino N: The relationships between trunk function and the findings of transcranial magnetic stimulation among stroke patients. J Rehabili Med 33: 249-255, 2001.
72. Fujiwara T, Hara Y, Akaboshi K, Chino N: Relationship between shoulder muscle strength and functional independence measure (FIM) score among C6 tetraplegics. Spinal Cord 37: 58-61, 1999.
73. Fujiwara T, Hara Y, Chino N: The influence of non-paretic leg movement on muscle action in the paretic leg of hemiplegic patients. Scand J Rehabil Med 31: 174-177, 1999.
74. Fujiwara T, Hara Y, Chino N: Expiratory function in complete tetraplegics: study of spirometry, maximal expiratory pressure, and muscle sctivity of pectoralis major and latissimus dorsi muscles. Am J Phys Med Rehabil 78: 464-469, 1999.

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