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東海林宏道（ショウジヒロミチ）

研究テーマ	胎内環境が早産児の栄養代謝に及ぼす影響についての検討
研究業績（論文）	・Shoji H, et al.Infant formula with 50% or more of palmitic acid bound to the sn-2 position of triglycerides eliminate the association between formula-feeding and the increase of fecal palmitic acid levels in newborns: an observational study. Nutrients 16:1558, 2024. ・Awata K, Shoji H, et al. Maternal protein restriction inhibits insulin signaling and insulin resistance in the skeletal muscle of young adult rats. Juntendo Med J, 2024 (in press). ・Saito H, Shoji H, et al. The head circumference to chest circumference ratio provided an easy way to detect foetal growth restriction in term infants. Acta Paediatr. 113:67-71, 2024. ・Ohkawa N, Shoji H, et al. The impact of cyclooxygenase inhibitor use on urinary prostaglandin metabolites in preterm infants. Pediatr Neonatol.S1875-9572(23)00132-8, 2023. ・Arai Y, Shoji H, et al.Effects of fetal growth restriction on postnatal gut microbiota in a rat model. J Pediatr Gastroenterol Nutr. 77:e42-e47, 2023, ・Tokita K, Shoji H, et al. Hepatic and skeletal muscle autophagy marker levels in rat models of prenatal and postnatal protein restriction. Nutrients. 15:3058, 2023, ・Santosa I, Shoji H, et al. Skeletal Muscle Insulin Resistance in a Novel Fetal Growth Restriction Model. Pediatr Rep. 2023;15:45-54. ・Shoji H, et al. Use of Head and Chest Circumference Ratio as an Index of Fetal Growth Retardation in Preterm Infants. Nutrients. 2022 Nov 21;14(22):4942. ・Shoji H, et al. Growth Trajectories during the First 6 Years in Survivors Born at Less Than 25 Weeks of Gestation Compared with Those between 25 and 29 Weeks.J Clin Med. 4;11:1418,2022. doi: 10.3390/jcm11051418. ・Santosa I, Shoji H, et al. Resistin in Urine and Breast Milk: Relation to Type of Feeding and Anthropometry at 1-Month.Pediatr Rep. 14:86-92, 2022. ・Murano Y, Shoji H, et al. Analysis of Factors Associated With Body Mass Index at Ages 18 and 36 Months Among Infants Born Extremely Preterm. JAMA Netw Open. 2021 Oct 1;4(10):e2128555.21;4:e2128555. ・Awata K, Shoji H, et al. Associations between size at birth and size at 6 years among preterm infants: a retrospective cohort study. Pediatr Int. 2021,May 17;64(1):e14844. ・Shoji H, et al. Intrauterine Growth Restriction Affects Z-Scores of Anthropometric Parameters During the First 6 Years in Very Low-Birth-Weight-Children Born at Less Than 30 Weeks of Gestation. J Dev Orig Health Dis. 11:44-48, 2020. ・Shoji H, et al. Choline-related metabolites influenced by feeding patterns in preterm and term infants. J Matern Fetal Neonatal Med. 33:230-235, 2020. ・Watanabe A, Shoji H, et al. Correlations between feeding type and blood ionized magnesium levels in Japanese preterm infants. Magnes Res. 2019 [Epub ahead of print]. ・Shoji H, et al. The role of human breast milk on biological metabolism in infants. Pediatr Int. 2019;61:6-15. ・Ashina M, Shoji H et al. Feeding interval and use of donor breast milk for very low birthweight infants: A nationwide survey in Japan. Pediatr Neonatol. 2019 ;60:245-251. ・Nishizaki N, Shoji H, et al. Association between the frequency of bedwetting and late preterm birth in children aged ≥5 years. Acta Paediatr. 2019;108:282-287. ・Suganuma H, Shoji H, et al. Influence of an intravenous lipid emulsion on lipoprotein subclasses in preterm infants. Pediatr Int.2018;60:839-843. ・Kantake M, Shoji H, et al. Shimizu T. Postnatal relative adrenal insufficiency results in methylation of the glucocorticoid receptor gene in preterm infants: a retrospective cohort study. Clin Epigenetics. 2018;18:10:66. ・Murano Y, Shoji H, et al. Long-term renal tubular damage in intrauterine growth-restricted rats. Pediatr Int. 2018;60:565-568. ・Nishizaki N, Shoji H, et al. Evaluation of urinary IL-6 in neonates with septic shock treated with polymyxin B-immobilized fiber column. Pediatr Int. 2017;59:1032-1033. ・Shoji H, et al. Urinary prostaglandin D2 metabolite excretion during the first six months of life was significantly lower in breast-fed than formula-fed infants. Acta Paediatr. 2018;107:95-100. ・Shoji H, et al.A pilot study of the effect of human breast milk on urinary metabolome analysis in infants.J Pediatr Endocrinol Metab.28;30:939-946,2017. ・Kojima C, Shoji H, et al.Association of zinc and copper with clinical parameters in the preterm newborn.Pediatr Int.59:1165-1168,2017. ・Shoji H, et al.Relationship between copper and lipids and atherogenic indices soon after birth in Japanese preterm infants of 32-35 weeks. J Dev Orig Health. 8:256-260,2017. ・Ohkawa N, Shoji H, et al.Relationship between IGF-1, leptin, and ghrelin levels and catch-up growth in small for gestational age infants of 27–31 weeks during neonatal intensive care unit admission. J Paediatr Child Health. 53:62-67,2017. ・Shoji H, et al.Influence of gestational age on serum incretin levels in preterm infant. J Dev Orig Health Dis.7:685-688,2016. ・Ikeda N and Shoji H, et al. Effect of insulin-like growth factor-I during the early postnatal period in intrauterine growth-restricted rats. Pediatr Int.58:353-8, 2016. ・Shoji H, Shimizu T. Parenteral Soybean Oil Lipid Emulsion in Very Low Birth Weight (VLBW) in Intensive Care. Diet and Nutrition in Critical Care. 1807-1815, 2015. ISBN: 978-1-4614-8503-2 ・東海林宏道.早産出生とメタボリックシンドローム．日本母乳哺育学会雑誌．10:e58-63,2016. ・東海林宏道：胎児発育不全児に対するニコチンアミドモノヌクレオチドの生活習慣病リスク低減効果．令和6年度　文部科学省科学研究費（基盤（C））. ・東海林宏道：RAASを介した胎児発育不全児における骨格筋インスリン抵抗性の機序解明.令和3年度　文部科学省科学研究費（基盤（C））. ・東海林宏道：早産児における尿メタボローム解析の有用性についての検討.平成27年度　文部科学省科学研究費（基盤（C））. ・東海林宏道：発育不全を伴う早産児におけるIGF-Iの役割とrhIGF-I投与に関する検討.平成24年度　文部科学省科学研究費（基盤（C））. ・東海林宏道: 胎児期の低栄養が早産児の消化管機能に及ぼす影響の検討．平成22年度　文部科学省科学研究費（若手研究（B））.

研究テーマ

胎内環境が早産児の栄養代謝に及ぼす影響についての検討

研究業績（論文）

・Shoji H, et al.Infant formula with 50% or more of palmitic acid bound to the sn-2 position of triglycerides eliminate the association between formula-feeding and the increase of fecal palmitic acid levels in newborns: an observational study. Nutrients 16:1558, 2024.
・Awata K, Shoji H, et al. Maternal protein restriction inhibits insulin signaling and insulin resistance in the skeletal muscle of young adult rats. Juntendo Med J, 2024 (in press).
・Saito H, Shoji H, et al. The head circumference to chest circumference ratio provided an easy way to detect foetal growth restriction in term infants. Acta Paediatr. 113:67-71, 2024.
・Ohkawa N, Shoji H, et al. The impact of cyclooxygenase inhibitor use on urinary prostaglandin metabolites in preterm infants. Pediatr Neonatol.S1875-9572(23)00132-8, 2023.
・Arai Y, Shoji H, et al.Effects of fetal growth restriction on postnatal gut microbiota in a rat model. J Pediatr Gastroenterol Nutr. 77:e42-e47, 2023,
・Tokita K, Shoji H, et al. Hepatic and skeletal muscle autophagy marker levels in rat models of prenatal and postnatal protein restriction. Nutrients. 15:3058, 2023,
・Santosa I, Shoji H, et al. Skeletal Muscle Insulin Resistance in a Novel Fetal Growth Restriction Model.
Pediatr Rep. 2023;15:45-54.
・Shoji H, et al. Use of Head and Chest Circumference Ratio as an Index of Fetal Growth Retardation in Preterm Infants.
Nutrients. 2022 Nov 21;14(22):4942.
・Shoji H, et al. Growth Trajectories during the First 6 Years in Survivors Born at Less Than 25 Weeks of Gestation Compared with Those between 25 and 29 Weeks.J Clin Med. 4;11:1418,2022. doi: 10.3390/jcm11051418.
・Santosa I, Shoji H, et al. Resistin in Urine and Breast Milk: Relation to Type of Feeding and Anthropometry at 1-Month.Pediatr Rep. 14:86-92, 2022.
・Murano Y, Shoji H, et al. Analysis of Factors Associated With Body Mass Index at Ages 18 and 36 Months Among Infants Born Extremely Preterm. JAMA Netw Open. 2021 Oct 1;4(10):e2128555.21;4:e2128555.
・Awata K, Shoji H, et al. Associations between size at birth and size at 6 years among preterm infants: a retrospective cohort study. Pediatr Int. 2021,May 17;64(1):e14844.
・Shoji H, et al. Intrauterine Growth Restriction Affects Z-Scores of Anthropometric Parameters During the First 6 Years in Very Low-Birth-Weight-Children Born at Less Than 30 Weeks of Gestation. J Dev Orig Health Dis. 11:44-48, 2020.
・Shoji H, et al. Choline-related metabolites influenced by feeding patterns in preterm and term infants. J Matern Fetal Neonatal Med. 33:230-235, 2020.
・Watanabe A, Shoji H, et al. Correlations between feeding type and blood ionized magnesium levels in Japanese preterm infants. Magnes Res. 2019 [Epub ahead of print].
・Shoji H, et al. The role of human breast milk on biological metabolism in infants. Pediatr Int. 2019;61:6-15.
・Ashina M, Shoji H et al. Feeding interval and use of donor breast milk for very low birthweight infants: A nationwide survey in Japan. Pediatr Neonatol. 2019 ;60:245-251.
・Nishizaki N, Shoji H, et al. Association between the frequency of bedwetting and late preterm birth in children aged ≥5 years. Acta Paediatr. 2019;108:282-287.
・Suganuma H, Shoji H, et al. Influence of an intravenous lipid emulsion on lipoprotein subclasses in preterm infants. Pediatr Int.2018;60:839-843.
・Kantake M, Shoji H, et al. Shimizu T. Postnatal relative adrenal insufficiency results in methylation of the glucocorticoid receptor gene in preterm infants: a retrospective cohort study. Clin Epigenetics. 2018;18:10:66.
・Murano Y, Shoji H, et al. Long-term renal tubular damage in intrauterine growth-restricted rats. Pediatr Int. 2018;60:565-568.
・Nishizaki N, Shoji H, et al. Evaluation of urinary IL-6 in neonates with septic shock treated with polymyxin B-immobilized fiber column. Pediatr Int. 2017;59:1032-1033.
・Shoji H, et al. Urinary prostaglandin D2 metabolite excretion during the first six months of life was significantly lower in breast-fed than formula-fed infants. Acta Paediatr. 2018;107:95-100.
・Shoji H, et al.A pilot study of the effect of human breast milk on urinary metabolome analysis in infants.J Pediatr Endocrinol Metab.28;30:939-946,2017.
・Kojima C, Shoji H, et al.Association of zinc and copper with clinical parameters in the preterm newborn.Pediatr Int.59:1165-1168,2017.
・Shoji H, et al.Relationship between copper and lipids and atherogenic indices soon after birth in Japanese preterm infants of 32-35 weeks. J Dev Orig Health. 8:256-260,2017.
・Ohkawa N, Shoji H, et al.Relationship between IGF-1, leptin, and ghrelin levels and catch-up growth in small for gestational age infants of 27–31 weeks during neonatal intensive care unit admission. J Paediatr Child Health. 53:62-67,2017.
・Shoji H, et al.Influence of gestational age on serum incretin levels in preterm infant. J Dev Orig Health Dis.7:685-688,2016.
・Ikeda N and Shoji H, et al. Effect of insulin-like growth factor-I during the early postnatal period in intrauterine growth-restricted rats. Pediatr Int.58:353-8, 2016.
・Shoji H, Shimizu T. Parenteral Soybean Oil Lipid Emulsion in Very Low Birth Weight (VLBW) in Intensive Care. Diet and Nutrition in Critical Care. 1807-1815, 2015. ISBN: 978-1-4614-8503-2
・東海林宏道.早産出生とメタボリックシンドローム．日本母乳哺育学会雑誌．10:e58-63,2016.

・東海林宏道：胎児発育不全児に対するニコチンアミドモノヌクレオチドの生活習慣病リスク低減効果．令和6年度　文部科学省科学研究費（基盤（C））.
・東海林宏道：RAASを介した胎児発育不全児における骨格筋インスリン抵抗性の機序解明.令和3年度　文部科学省科学研究費（基盤（C））.
・東海林宏道：早産児における尿メタボローム解析の有用性についての検討.平成27年度　文部科学省科学研究費（基盤（C））.
・東海林宏道：発育不全を伴う早産児におけるIGF-Iの役割とrhIGF-I投与に関する検討.平成24年度　文部科学省科学研究費（基盤（C））.
・東海林宏道: 胎児期の低栄養が早産児の消化管機能に及ぼす影響の検討．平成22年度　文部科学省科学研究費（若手研究（B））.

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研究業績詳細

東海林 宏道（ショウジ ヒロミチ）

東海林宏道（ショウジヒロミチ）