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研究業績詳細

築根豊（ツクネユタカ）

研究テーマ	血液内科学　多発性骨髄腫
研究業績（論文）	1. Sasaki M, Isobe Y, Tsukune Y, Kawahara S, Hamano Y, Ando J, Tomomatsu J, Tsutsui M, Sugimoto K. Thalidomide may induce interstitial pneumonia preferentially in Japanese patients. Eur J Haematol. 2009; 82: 73-4. 2. Isobe Y, Kanemitsu N, Yahata Y, Masuda A, Tsukune Y, Sugimoto K. Clinical and microbiological effects of biapenem in febrile neutropenic patients with hematologic malignancies. Scand J Infect Dis. 2009; 41: 237-9. 3. Sasaki M, Aritaka N, Tsukune Y, Kawahara S, Masuda A, Tsutsui M, Kanemitsu N, Sugimoto K. Establishment of a hairy cell leukemia variant cell line, HCLv-07. Acta Haematol. 2009; 121: 63-6. 4. Tsukune Y, Isobe Y, Yasuda H, Shimizu S, Katsuoka Y, Hosone M, Oshimi K, Komatsu N, Sugimoto K. Activity and safety of combination chemotherapy with methotrexate, ifosfamide, l-asparaginase and dexamethasone (MILD) for refractory lymphoid malignancies: a pilot study. Eur J Haematol. 2010; 84: 310-5. 5. Sasaki M, Sugimoto K, Masuda A, Tsukune Y, Yahata Y, Komatsu N. Early CNS relapse in a good-risk primary mediastinal large B-cell lymphoma after combined chemo- and radio-therapy. J Neurooncol. 2010; 99: 295-6. 6. Mori T, Yahata Y, Tsukune Y. Zygomycosis. Med Mycol J. 2011; 52: 283-9. 7. Isobe Y, Tomomatsu J, Tsukune Y, Tsukada N, Sasaki M, Sugimoto K, Komatsu N. Diagnostic problems among chronic lymphocytic leukemia and other indolent B-cell leukemias in a Japanese population. Intern Med. 2012; 51: 1977-81. 8. Yamada A, Sugimoto K, Matuno K, Tutui M, Yahata Y, Tsukune Y, Koike M, Komatsu N. Primary pleural of mucosa-associated lymphoid tissue lymphoma. Rinsho Ketsueki. 2013; 54: 463-7. 9. Tsukune Y, Sasaki M, Odajima T, Isoda A, Matsumoto M, Koike M, Tamura H, Moriya K, Ito S, Asahi M, Imai Y, Tanaka J, Handa H, Koiso H, Tanosaki S, Hua J, Hagihara M, Yahata Y, Suzuki S, Watanabe S, Sugimori H, Komatsu N. Incidence and clinical background of hepatitis B virus reactivation in multiple myeloma in novel agents' era. Ann Hematol. 2016; 95: 1465-72. 10. Tsukune Y, Komatsu N. Management of Adult Chronic Immune Thrombocytopenia in Japan: Patient and Hematologist Perspectives from a Multi-center Cross-sectional Questionnaire Survey. Intern Med. 2016; 55: 2379-85. 11. Tsukune Y, Yahata Y, Sasaki M, Hiki M, Tsutsui M, Hamano Y, Itoh S, Miyazaki T, Dohi T, Maruyama M, Gotoh A, Komatsu N. Clinical benefits of bortezomib-containing regimens for newly diagnosed AL amyloidosis with severe cardiac impairment. Rinsho Ketsueki. 2016; 57: 987-93. 12. Saito A, Isoda A, Kojima M, Yokohama A, Tsukune Y, Sasaki M, Ito S, Ohtsu A, Koike M, Murayama K, Moriya K, Tamura H, Matsumoto M, Nakahashi H, Tanosaki S, Sakura T, Kawamura T, Miyanaga T, Nakamura N, Murakami H, Handa H, Tsukamoto N. Retrospective analysis of prognostic factors for Waldenstrӧm macroglobulinemia: a multicenter cooperative study in Japan. Int J Hematol. 2017; 106: 681-90. 13. Tsukune Y, Sasaki M, Odajima T, Sunami K, Takei T, Moriuchi Y, Iino M, Isoda A, Nakaya A, Muta T, Miyake T, Miyazaki K, Shimizu T, Nakajima K, Igarashi A, Nagafuji K, Kurihara T, Aoyama T, Sugimori H, Komatsu N. Incidence and risk factors of hepatitis B virus reactivation in patients with multiple myeloma in an era with novel agents: a nationwide retrospective study in Japan. Blood Cancer J. 2017; 7: 631. 14. Edahiro Y, Takaku T, Konishi H, Tsukune Y, Fujioka I, Takasu K, Gotoh A, Daida H, Komatsu N. Chronic myeloid leukemia complicated by pulmonary hypertension during dasatinib therapy: a single-center retrospective study. Rinsho Ketsueki. 2017; 58: 2213-18. 15. Edahiro Y, Gotoh A, Inano T, Tsutsui M, Tsukune Y, Yasuda H, Komatsu N. Transfusion independence achieved with pomalidomide therapy in a patient with primary myelofibrosis. Rinsho Ketsueki. 2018; 59: 323-25. 16. Hatano T, Takanashi M, Tsuchihashi H, Ueno SI, Hayashida A, Tsukune Y, Kanai K, Shimo Y, Hattori N. Myalgia caused by chronic myositis associated with plasmacytosis: a case report. BMC Neurol. 2018; 18: 112. 17. Ishibashi M, Soeda S, Sasaki M, Handa H, Imai Y, Tanaka N, Tanosaki S, Ito S, Odajima T, Sugimori H, Asayama T, Sunakawa M, Kaito Y, Kinoshita R, Kuribayashi Y, Onodera A, Moriya K, Tanaka J, Tsukune Y, Komatsu N, Inokuchi K, Tamura H. Clinical impact of serum soluble SLAMF7 in multiple myeloma. Oncotarget. 2018; 9: 34784-93. 18. Tsukune Y, Sasaki M, Isoda A, Ando J, Koike M, Matsumoto M, Sawamura M, Tamura H, Handa H, Imai Y, Yahata Y, Komatsu N. Safety of lenalidomide, dexamethasone, and cyclophosphamide in elderly Japanese patients with relapsed and refractory multiple myeloma: results of phase 1 study. International Journal of Myeloma. 2019; 9: 1-6. 19. Yasuda H, Tsutsui M, Ando J, Inano T, Noguchi M, Yahata Y, Tanaka M, Tsukune Y, Masuda A, Shirane S, Misawa K, Gotoh A, Sato E, Aritaka N, Sekiguchi Y, Sugimoto K, Komatsu N. Vitamin B6 deficiency is prevalent in primary and secondary myelofibrosis patients. Int J Hematol. 2019; 110: 543-9. 20. Tsukune Y, Sasaki M, Komatsu N: Reactivation of hepatitis B virus in patients with multiple myeloma. Cancers. 2019; 11: 1819. 21. Ishibashi M, Takahashi R, Tsubota A, Sasaki M, Handa H, Imai Y, Tanaka N, Tsukune Y, Tanosaki S, Ito S, Asayama T, Sunakawa M, Kaito Y, Kuribayashi-Hamada Y, Onodera A, Moriya K, Komatsu N, Tanaka J, Odajima T, Sugimori H, Inokuchi K, Tamura H. SLAMF3-Mediated Signaling via ERK Pathway Activation Promotes Aggressive Phenotypic Behaviors in Multiple Myeloma. Mol Cancer Res. 2020; 18: 632-43. 22. Yasuda H, Tsukune Y, Watanabe N, Sugimoto K, Uchimura A, Tateyama M, Miyashita Y, Ochi Y, Komatsu N. Persistent COVID-19 Pneumonia and Failure to Develop Anti-SARS-CoV-2 Antibodies During Rituximab Maintenance Therapy for Follicular Lymphoma. Clin Lymphoma Myeloma Leuk. 2020; 20: 774-6. 23. Yasuda H, Tsukune Y, Inano T, Mori Y, Ota Y, Komatsu N. Successful Long-Term Ibrutinib Treatment in a Hemodialysis Patient With Leukemic Nonnodal Mantle Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2021; 21: e176-e178. 24. Yasuda H, Morishita S, Mori Y, Tsukune Y, Inano T, Harada S, Komatsu N. JAK2/CALR/SF3B1 triple-mutated myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis evolving to myelofibrosis and SF3B1 single-mutated acute myeloid leukemia: Evidence of a pre-JAK2 clone. Leuk Res. 2021; 100: 106496. 25. Haraguchi M, Harada N, Watanabe J, Yoshikawa H, Shirai Y, Komura M, Koyama M, Ito J, Tsukune Y, Horimoto Y, Hayashi T, Nagaoka T, Uekusa T, Takahashi K. Disseminated nontuberculous mycobacteriosis and fungemia after second delivery in a patient with MonoMAC syndrome/GATA2 mutation: a case report. BMC Infect Dis. 2021; 21: 502. 26. Yasui H, Kobayashi M, Sato K, Kondoh K, Ishida T, Kaito Y, Tamura H, Handa H, Tsukune Y, Sasaki M, Komatsu N, Tanaka N, Tanaka J, Kizaki M, Kawamata T, Makiyama J, Yokoyama K, Imoto S, Tojo A, Imai Y: Circulating cell-free DNA in the peripheral blood plasma of patients is an informative biomarker for multiple myeloma relapse. Int J Clin Oncol. 2021; 26: 2142. 27. Mori T, Abe H, Yoshida M, Tsukune Y, Yahata Y, Takaku T, Ando J, Ando M, Torii S, Sasaki M: Immunohistochemical detection of aflatoxin in lesions of aflatoxin-producing aspergillus flavus infection. Med Mycol J. 2021; 62: 47. 28. Sano M, Iseki T, Sasaki M, Tsukune Y, Yasuda H, Kanazawa K, Arakawa A, Yokoyama K, Komatsu N, Hattori N, Nishioka K: Improvement in the symptoms and VEGF levels after resection of an extramedullary spinal tumor and additional chemotherapy in a patient with multiple myeloma complicated with POEMS syndrome. Intern Med. 2021; 60: 3625. 29. Inano T, Yasuda H, Tsukune Y, Tsutsui M, Wali N, Saeki H, Kajino K, Hino O, Masaki Y, Komatsu N. Abnormal Exacerbation of Moderately Differentiated Gastric Adenocarcinoma in a Patient with TAFRO Syndrome: An Impaired Tumor Immunity? Case Rep Oncol. 2022; 15: 7. 30. Watanabe N, Takaku T, Tsukune Y, Yasuda H, Ochiai T, Yamada K, Nakazawa H, Hotta S, Nishimaki T, Takagi H, Takahashi K, Komatsu N, Ando M. Bosutinib-induced lung injury: a report of two cases and literature review. Int J Hematol. 2022; 115: 902. 31. Yasuda H, Furukawa Y, Nishioka K, Sasaki M, Tsukune Y, Shirane S, Hattori N, Ando M, Komatsu N. Vitamin B6 deficiency as a cause of polyneuropathy in POEMS syndrome: rapid recovery with supplementation in two cases. Hematology. 2022; 27: 463. 32. Uchimura A, Yasuda H, Ando J, Ota Y, Sasaki M, Takaku T, Tsukune Y, Tsutsui M, Edahiro Y, Watanabe N, Ochiai T, Komatsu N, Ando M. Hodgkin Lymphoma on Hemodialysis Successfully Treated with Extended Courses of Brentuximab Vedotin. Case Rep Oncol. 2022; 15: 263. 33. Edahiro Y, Koike M, Nojiri S, Harada Y, Gotoh A, Fujibayashi K, Nishizaki Y, Yanagisawa N, Takaku T, Nitta H, Tsukune Y, Misawa K, Kobayashi H, Komatsu N. A pilot study examining the efficacy of hochuekkito for improving quality of life in patients with myeloproliferative neoplasms. Jpn J Clin Oncol. 2022; 52: 880. 34. Kaito Y, Sugimoto E, Nakamura F, Tsukune Y, Sasaki M, Yui S, Yamaguchi H, Goyama S, Nannya Y, Mitani K, Tamura H, Imai Y. Immune checkpoint molecule DNAM-1/CD112 axis is a novel target for natural killer-cell therapy in acute myeloid leukemia. Haematologica. 2024; 109: 1107. 35. Shibayama H, Itagaki M, Handa H, Yokoyama A, Saito A, Kosugi S, Ota S, Yoshimitsu M, Tanaka Y, Kurahashi S, Fuchida SI, Iino M, Shimizu T, Moriuchi Y, Toyama K, Mitani K, Tsukune Y, Kada A, Tamura H, Abe M, Iwasaki H, Kuroda J, Takamatsu H, Sunami K, Kizaki M, Ishida T, Saito T, Matsumura I, Akashi K, Iida S. Primary analysis of a prospective cohort study of Japanese patients with plasma cell neoplasms in the novel drug era (2016-2021). Int J Hematol. 2024; 119: 707. 36. Furukawa Y, Ando J, Ishii M, Kinoshita S, Goto A, Tachibana K, Azusawa Y, Kato T, Izumi N, Hosoya E, Uchimura A, Inano T, Shirane S, Tsukune Y, Takaku T, Hamano Y, Ando M.l-asparaginase monotherapy as an encouraging approach towards acute fulminant chronic active Epstein-Barr virus infection. Br J Haematol. 2024; 205: 1610. 37. Hosoya E, Ando J, Kinoshita S, Furukawa Y, Toyoshima Y, Azusawa Y, Mitsumori T, Sato E, Takano H, Tsukune Y, Watanabe N, Takaku T, Yasuda H, Hamano Y, Sasaki M, Nojiri S, Ishii M, Ando M. Eleven cases of laryngeal edema after tisagenlecleucel infusion: a 3-year single center retrospective study of CD19-directed chimeric antigen receptor T-cell therapy for relapsed and refractory B-cell lymphomas. Haematologica. 2025; 110: 777. 38. Yanashima K, Furukawa Y, Ishii M, Kinoshita S, Hamano Y, Watanabe N, Tsukune Y, Yasuda H, Ando J, Ando M. Early Epcoritamab Administration Revives CAR-T Cells in Relapsed/Refractory B-Cell Lymphomas. EJHaem. 2025; 6: e70079. 39. Suzuki K, Watanabe N, Tsukune Y, Inano T, Kinoshita S, Tomoda S, Yamada K, Konishi Y, Kuwana T, Sugiyama T, Fukada K, Yamada K, Ando M, Takaku T. Artificial intelligence-driven label-free detection of chronic myeloid leukemia cells using ghost cytometry. Sci Rep. 2025; 15: 21046.

研究テーマ

血液内科学　多発性骨髄腫

研究業績（論文）

1. Sasaki M, Isobe Y, Tsukune Y, Kawahara S, Hamano Y, Ando J, Tomomatsu J, Tsutsui M, Sugimoto K. Thalidomide may induce interstitial pneumonia preferentially in Japanese patients. Eur J Haematol. 2009; 82: 73-4.

2. Isobe Y, Kanemitsu N, Yahata Y, Masuda A, Tsukune Y, Sugimoto K. Clinical and microbiological effects of biapenem in febrile neutropenic patients with hematologic malignancies. Scand J Infect Dis. 2009; 41: 237-9.

3. Sasaki M, Aritaka N, Tsukune Y, Kawahara S, Masuda A, Tsutsui M, Kanemitsu N, Sugimoto K. Establishment of a hairy cell leukemia variant cell line, HCLv-07. Acta Haematol. 2009; 121: 63-6.

4. Tsukune Y, Isobe Y, Yasuda H, Shimizu S, Katsuoka Y, Hosone M, Oshimi K, Komatsu N, Sugimoto K. Activity and safety of combination chemotherapy with methotrexate, ifosfamide, l-asparaginase and dexamethasone (MILD) for refractory lymphoid malignancies: a pilot study. Eur J Haematol. 2010; 84: 310-5.

5. Sasaki M, Sugimoto K, Masuda A, Tsukune Y, Yahata Y, Komatsu N. Early CNS relapse in a good-risk primary mediastinal large B-cell lymphoma after combined chemo- and radio-therapy. J Neurooncol. 2010; 99: 295-6.

6. Mori T, Yahata Y, Tsukune Y. Zygomycosis. Med Mycol J. 2011; 52: 283-9.

7. Isobe Y, Tomomatsu J, Tsukune Y, Tsukada N, Sasaki M, Sugimoto K, Komatsu N. Diagnostic problems among chronic lymphocytic leukemia and other indolent B-cell leukemias in a Japanese population. Intern Med. 2012; 51: 1977-81.

8. Yamada A, Sugimoto K, Matuno K, Tutui M, Yahata Y, Tsukune Y, Koike M, Komatsu N. Primary pleural of mucosa-associated lymphoid tissue lymphoma. Rinsho Ketsueki. 2013; 54: 463-7.

9. Tsukune Y, Sasaki M, Odajima T, Isoda A, Matsumoto M, Koike M, Tamura H, Moriya K, Ito S, Asahi M, Imai Y, Tanaka J, Handa H, Koiso H, Tanosaki S, Hua J, Hagihara M, Yahata Y, Suzuki S, Watanabe S, Sugimori H, Komatsu N. Incidence and clinical background of hepatitis B virus reactivation in multiple myeloma in novel agents' era. Ann Hematol. 2016; 95: 1465-72.

10. Tsukune Y, Komatsu N. Management of Adult Chronic Immune Thrombocytopenia in Japan: Patient and Hematologist Perspectives from a Multi-center Cross-sectional Questionnaire Survey. Intern Med. 2016; 55: 2379-85.

11. Tsukune Y, Yahata Y, Sasaki M, Hiki M, Tsutsui M, Hamano Y, Itoh S, Miyazaki T, Dohi T, Maruyama M, Gotoh A, Komatsu N. Clinical benefits of bortezomib-containing regimens for newly diagnosed AL amyloidosis with severe cardiac impairment. Rinsho Ketsueki. 2016; 57: 987-93.

12. Saito A, Isoda A, Kojima M, Yokohama A, Tsukune Y, Sasaki M, Ito S, Ohtsu A, Koike M, Murayama K, Moriya K, Tamura H, Matsumoto M, Nakahashi H, Tanosaki S, Sakura T, Kawamura T, Miyanaga T, Nakamura N, Murakami H, Handa H, Tsukamoto N. Retrospective analysis of prognostic factors for Waldenstrӧm macroglobulinemia: a multicenter cooperative study in Japan. Int J Hematol. 2017; 106: 681-90.

13. Tsukune Y, Sasaki M, Odajima T, Sunami K, Takei T, Moriuchi Y, Iino M, Isoda A, Nakaya A, Muta T, Miyake T, Miyazaki K, Shimizu T, Nakajima K, Igarashi A, Nagafuji K, Kurihara T, Aoyama T, Sugimori H, Komatsu N. Incidence and risk factors of hepatitis B virus reactivation in patients with multiple myeloma in an era with novel agents: a nationwide retrospective study in Japan. Blood Cancer J. 2017; 7: 631.

14. Edahiro Y, Takaku T, Konishi H, Tsukune Y, Fujioka I, Takasu K, Gotoh A, Daida H, Komatsu N. Chronic myeloid leukemia complicated by pulmonary hypertension during dasatinib therapy: a single-center retrospective study. Rinsho Ketsueki. 2017; 58: 2213-18.

15. Edahiro Y, Gotoh A, Inano T, Tsutsui M, Tsukune Y, Yasuda H, Komatsu N. Transfusion independence achieved with pomalidomide therapy in a patient with primary myelofibrosis. Rinsho Ketsueki. 2018; 59: 323-25.

16. Hatano T, Takanashi M, Tsuchihashi H, Ueno SI, Hayashida A, Tsukune Y, Kanai K, Shimo Y, Hattori N. Myalgia caused by chronic myositis associated with plasmacytosis: a case report. BMC Neurol. 2018; 18: 112.

17. Ishibashi M, Soeda S, Sasaki M, Handa H, Imai Y, Tanaka N, Tanosaki S, Ito S, Odajima T, Sugimori H, Asayama T, Sunakawa M, Kaito Y, Kinoshita R, Kuribayashi Y, Onodera A, Moriya K, Tanaka J, Tsukune Y, Komatsu N, Inokuchi K, Tamura H. Clinical impact of serum soluble SLAMF7 in multiple myeloma. Oncotarget. 2018; 9: 34784-93.

18. Tsukune Y, Sasaki M, Isoda A, Ando J, Koike M, Matsumoto M, Sawamura M, Tamura H, Handa H, Imai Y, Yahata Y, Komatsu N. Safety of lenalidomide, dexamethasone, and cyclophosphamide in elderly Japanese patients with relapsed and refractory multiple myeloma: results of phase 1 study. International Journal of Myeloma. 2019; 9: 1-6.

19. Yasuda H, Tsutsui M, Ando J, Inano T, Noguchi M, Yahata Y, Tanaka M, Tsukune Y, Masuda A, Shirane S, Misawa K, Gotoh A, Sato E, Aritaka N, Sekiguchi Y, Sugimoto K, Komatsu N. Vitamin B6 deficiency is prevalent in primary and secondary myelofibrosis patients. Int J Hematol. 2019; 110: 543-9.

20. Tsukune Y, Sasaki M, Komatsu N: Reactivation of hepatitis B virus in patients with multiple myeloma. Cancers. 2019; 11: 1819.

21. Ishibashi M, Takahashi R, Tsubota A, Sasaki M, Handa H, Imai Y, Tanaka N, Tsukune Y, Tanosaki S, Ito S, Asayama T, Sunakawa M, Kaito Y, Kuribayashi-Hamada Y, Onodera A, Moriya K, Komatsu N, Tanaka J, Odajima T, Sugimori H, Inokuchi K, Tamura H. SLAMF3-Mediated Signaling via ERK Pathway Activation Promotes Aggressive Phenotypic Behaviors in Multiple Myeloma. Mol Cancer Res. 2020; 18: 632-43.

22. Yasuda H, Tsukune Y, Watanabe N, Sugimoto K, Uchimura A, Tateyama M, Miyashita Y, Ochi Y, Komatsu N. Persistent COVID-19 Pneumonia and Failure to Develop Anti-SARS-CoV-2 Antibodies During Rituximab Maintenance Therapy for Follicular Lymphoma. Clin Lymphoma Myeloma Leuk. 2020; 20: 774-6.

23. Yasuda H, Tsukune Y, Inano T, Mori Y, Ota Y, Komatsu N. Successful Long-Term Ibrutinib Treatment in a Hemodialysis Patient With Leukemic Nonnodal Mantle Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2021; 21: e176-e178.

24. Yasuda H, Morishita S, Mori Y, Tsukune Y, Inano T, Harada S, Komatsu N. JAK2/CALR/SF3B1 triple-mutated myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis evolving to myelofibrosis and SF3B1 single-mutated acute myeloid leukemia: Evidence of a pre-JAK2 clone. Leuk Res. 2021; 100: 106496.

25. Haraguchi M, Harada N, Watanabe J, Yoshikawa H, Shirai Y, Komura M, Koyama M, Ito J, Tsukune Y, Horimoto Y, Hayashi T, Nagaoka T, Uekusa T, Takahashi K. Disseminated nontuberculous mycobacteriosis and fungemia after second delivery in a patient with MonoMAC syndrome/GATA2 mutation: a case report. BMC Infect Dis. 2021; 21: 502.

26. Yasui H, Kobayashi M, Sato K, Kondoh K, Ishida T, Kaito Y, Tamura H, Handa H, Tsukune Y, Sasaki M, Komatsu N, Tanaka N, Tanaka J, Kizaki M, Kawamata T, Makiyama J, Yokoyama K, Imoto S, Tojo A, Imai Y: Circulating cell-free DNA in the peripheral blood plasma of patients is an informative biomarker for multiple myeloma relapse. Int J Clin Oncol. 2021; 26: 2142.

27. Mori T, Abe H, Yoshida M, Tsukune Y, Yahata Y, Takaku T, Ando J, Ando M, Torii S, Sasaki M: Immunohistochemical detection of aflatoxin in lesions of aflatoxin-producing aspergillus flavus infection. Med Mycol J. 2021; 62: 47.

28. Sano M, Iseki T, Sasaki M, Tsukune Y, Yasuda H, Kanazawa K, Arakawa A, Yokoyama K, Komatsu N, Hattori N, Nishioka K: Improvement in the symptoms and VEGF levels after resection of an extramedullary spinal tumor and additional chemotherapy in a patient with multiple myeloma complicated with POEMS syndrome. Intern Med. 2021; 60: 3625.

29. Inano T, Yasuda H, Tsukune Y, Tsutsui M, Wali N, Saeki H, Kajino K, Hino O, Masaki Y, Komatsu N. Abnormal Exacerbation of Moderately Differentiated Gastric Adenocarcinoma in a Patient with TAFRO Syndrome: An Impaired Tumor Immunity? Case Rep Oncol. 2022; 15: 7.

30. Watanabe N, Takaku T, Tsukune Y, Yasuda H, Ochiai T, Yamada K, Nakazawa H, Hotta S, Nishimaki T, Takagi H, Takahashi K, Komatsu N, Ando M. Bosutinib-induced lung injury: a report of two cases and literature review. Int J Hematol. 2022; 115: 902.

31. Yasuda H, Furukawa Y, Nishioka K, Sasaki M, Tsukune Y, Shirane S, Hattori N, Ando M, Komatsu N. Vitamin B6 deficiency as a cause of polyneuropathy in POEMS syndrome: rapid recovery with supplementation in two cases. Hematology. 2022; 27: 463.

32. Uchimura A, Yasuda H, Ando J, Ota Y, Sasaki M, Takaku T, Tsukune Y, Tsutsui M, Edahiro Y, Watanabe N, Ochiai T, Komatsu N, Ando M. Hodgkin Lymphoma on Hemodialysis Successfully Treated with Extended Courses of Brentuximab Vedotin. Case Rep Oncol. 2022; 15: 263.

33. Edahiro Y, Koike M, Nojiri S, Harada Y, Gotoh A, Fujibayashi K, Nishizaki Y, Yanagisawa N, Takaku T, Nitta H, Tsukune Y, Misawa K, Kobayashi H, Komatsu N. A pilot study examining the efficacy of hochuekkito for improving quality of life in patients with myeloproliferative neoplasms. Jpn J Clin Oncol. 2022; 52: 880.

34. Kaito Y, Sugimoto E, Nakamura F, Tsukune Y, Sasaki M, Yui S, Yamaguchi H, Goyama S, Nannya Y, Mitani K, Tamura H, Imai Y. Immune checkpoint molecule DNAM-1/CD112 axis is a novel target for natural killer-cell therapy in acute myeloid leukemia. Haematologica. 2024; 109: 1107.

35. Shibayama H, Itagaki M, Handa H, Yokoyama A, Saito A, Kosugi S, Ota S, Yoshimitsu M, Tanaka Y, Kurahashi S, Fuchida SI, Iino M, Shimizu T, Moriuchi Y, Toyama K, Mitani K, Tsukune Y, Kada A, Tamura H, Abe M, Iwasaki H, Kuroda J, Takamatsu H, Sunami K, Kizaki M, Ishida T, Saito T, Matsumura I, Akashi K, Iida S. Primary analysis of a prospective cohort study of Japanese patients with plasma cell neoplasms in the novel drug era (2016-2021). Int J Hematol. 2024; 119: 707.

36. Furukawa Y, Ando J, Ishii M, Kinoshita S, Goto A, Tachibana K, Azusawa Y, Kato T, Izumi N, Hosoya E, Uchimura A, Inano T, Shirane S, Tsukune Y, Takaku T, Hamano Y, Ando M.l-asparaginase monotherapy as an encouraging approach towards acute fulminant chronic active Epstein-Barr virus infection. Br J Haematol. 2024; 205: 1610.

37. Hosoya E, Ando J, Kinoshita S, Furukawa Y, Toyoshima Y, Azusawa Y, Mitsumori T, Sato E, Takano H, Tsukune Y, Watanabe N, Takaku T, Yasuda H, Hamano Y, Sasaki M, Nojiri S, Ishii M, Ando M. Eleven cases of laryngeal edema after tisagenlecleucel infusion: a 3-year single center retrospective study of CD19-directed chimeric antigen receptor T-cell therapy for relapsed and refractory B-cell lymphomas. Haematologica. 2025; 110: 777.

38. Yanashima K, Furukawa Y, Ishii M, Kinoshita S, Hamano Y, Watanabe N, Tsukune Y, Yasuda H, Ando J, Ando M. Early Epcoritamab Administration Revives CAR-T Cells in Relapsed/Refractory B-Cell Lymphomas. EJHaem. 2025; 6: e70079.

39. Suzuki K, Watanabe N, Tsukune Y, Inano T, Kinoshita S, Tomoda S, Yamada K, Konishi Y, Kuwana T, Sugiyama T, Fukada K, Yamada K, Ando M, Takaku T. Artificial intelligence-driven label-free detection of chronic myeloid leukemia cells using ghost cytometry. Sci Rep. 2025; 15: 21046.

研究者

教育活動

【学校法人順天堂】研究者情報データベース

研究業績詳細

築根 豊（ツクネ ユタカ）

築根豊（ツクネユタカ）