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研究業績詳細

村上晶（ムラカミアキラ）

研究テーマ	失明予防, 網膜色素変性、遺伝学
研究業績（論文）	1. Murakami A, Konomi H, Itokazu N, Arima M, Sakuragawa N, Nakajima A, Tanaka M, Tajima S, Hayashi T, Kino J: Partial characterization of an　usual 185kDa protein synthesized by dermal fibroblasts from patients with Marfan syndrome. J Biochem 106: 490-494,1989. 2. Mashima Y, Murakami A, Welber R, Kennaway N, Clarke L, Shiono T, Inana G: Nonsense-codon mutation of the ornithine aminotransferase gene with decreased level of mutant mRNA in Gyrate Atrophy. Am J Hum Genet. 51:81-91, 1992. 3. Akaki Y, Hotta Y, Mashima Y, Murakami A, Kennaway N, Welber R, Inana G: A deletion in the ornithine aminotransferase gene in the gyrate atrophy. J Biol Chem 267: 12950-12954, 1992. 4. Murakami A, Yajima T, Inana G: Isolation of human retinal genes: recoverin cDNA and gene. Biochem Biophys Res Commun. 187: 234-244, 1992. 5. Murakami A, Yajima T, Sakuma H, Mclaren M, Inana G: X-arrestin: a new retinal arrestin mapping to the X chromosome. FEBS Letters. 334: 203-209, 1993. 6. Fujiki K, Hotta Y, Murakami A, Yoshii M, Hayakawa M, Ichikawa T, Takeda M, Akeo K, Okisaka S, Kanai A: Missense mutation of rhodopsin gene codon 15 found in Japanese autosomal dominant retinitis pigmentosa. Jpn J Hum Genet. 40: 271-277, 1995. 7. Sakuma H, Inana G, Murakami A, Yajima T, Welber R, Murphey W, Gass D, Hotta Y, Hayakawa M, Fujiki K, Gao YQ, Danciger M, Farber D, Cideciyan A, Jacobson S: A heterozygous putative null mutation in ROM1 without a mutation in Peripherin/RDS in a family with retinitis pigmentosa. Genomics 27: 384-386, 1995. 8. Higashide T, Murakami A, McLaren M, Inana G: Cloning of the cDNA for a novel photoreceptor protein. J Biol Chem 271: 1797-1804, 1996. 9. Sakuma H, Inana G, Murakami A, Higashide T, McLaren M: Immunolocalization of X-arrestin in human cone photoreceptor: FEBS Letters. 382: 105-110, 1996. 10. Parminder A, Murakami A, Inana G, Berson E, Dryja T: Evaluation of the human gene encoding recoverin in patients with retinitis pigmentosa or an allied disease. Invest Ophthalmol Vis Sci 388: 704-709,1997. 11. Okisaka S, Murakami A, Mizukawa A, Ito J: Apoptosis in retinal ganglion cell decrease in human glaucomatous eyes. Jpn J Ophthalmol 41: 84-88, 1997. 12. Yoshii M, Murakami A, Akeo K, Fujiki K，Saga M, Mizukawa A, Itoh J, Okisaka S, Yanashima K, Hotta Y, Kanai A, Oguchi Y: Visual function in retinitis pigmentosa related to a codon 15 rhodopsin gene mutation. Ophthalmic Res 30: 1-10, 1998. 13. Yoshii M, Murakami A, Akeo K, Nakamura A, Shimoyama M, Ikeda Y, Kikuchi Y, Okisaka S, Yanashima K, Oguchi Y: Visual function and gene analysis in a family with Oguchi’s disease. Ophthalmic Res 30: 394-401,1998. 14. Sakuma H, Murakami A, Fujimaki T, Inana G: Isolation and characterization of the human X-arrestin gene. Gene 224: 87-95, 1998. 15. Nakagami T, Murakami A, Okisaka S, Ebihara N: Mast cells in pterygium: Number and phenotype. Jpn J Ophthalmol 43: 75-79, 1999. 16. Fujiki K, Hotta Y, Hayakawa M, Saito A, Mashima Y, Mori M, Yoshii M, Murakami A, Matsumoto M, Hayasaka S, Tagami N, Isashiki Y, Ohba N, Kanai A: REP-1 gene mutations in Japanese patients with choroideremia. Graefe’s Arch Clin Exp Ophthalmol 237: 735-740, 1999. 17. Maeda T, Ohguro H, Sohma H, Kuroki Y, Wada H, Okisaka S, Murakami A: Purification and characterization of bovine cone arrestin(cArr). FEBS Lett. 470: 336-340, 2000. 18. Nakagami T, Watanabe I, Murakami A, Okisaka S, Ebihara N: Expression of stem cell factor in pterygium. Jpn J Ophthalmol 44:193-197, 2000. 19. Karasawa Y, Murakami A, Okisaka S: Apoptosis after butyrate-induced differentiation in retinoblastoma cell line Y-79. Jpn J Ophthalmol 44:601-609, 2000. 20. Murakami A, Fujiki K, Hasegawa S, Imamura S, Kawano H, Kanai A, Matsumoto M: Transthyretin Ser-44 mutation in a case with vitreous amyloidosis. Am J Ophthalmol 133: 272-273, 2002. 21. Ha NT, Murakami A, Fujiki K, Kanai A: Transferrin-polyethylenimine conjugate, FuGENE6, and TransIT-LT as non-viral vectors for gene transfer to the corneal endothelium. Jpn J Ophthalmol 46: 140-146, 2002. 22. Takahashi K, Takahashi K, Murakami A, Okisaka S, Kimura T, Kanai A: Heterozygous Ala137Pro mutation in keratin 12 gene found in Japanese Meesmann’s corneal dystrophy. Jpn J Ophthalmol 46:673-674, 2002. 23. Ha NT, Chau HM, Cung LX, Thanh TK, Fujiki K, Murakami A, Kanai A: A novel mutation of M1S1 gene found in a Vietnamese patient with gelatinous droplike corneal dystrophy. Am J Ophthalmol 135:391-392, 2003. 24. Chau HM, Ha NT, Cung LX, Thanh TK, Fujiki K, Murakami A, Kanai A:H626R and R124C mutations of the TGFB1(BIGH3) gene caused lattice corneal dystrophy in Vietnamese people. Br J Ophthalmol 87:686-689, 2003. 25. Zhang Y, Kimura T, Fujiki K, Sakuma H, Murakami A, Kanai A: Multiples polymerase chain reaction for detection of herpes simplex virus Type 1, Type 2, Cytomegalovirus, and Varicella-Zoster virus in ocular viral infections. Jpn J Ophthalmol 47:260-264, 2003. 26. Ha NT, Cung LX, Chau HM, Thanh TK, Fujiki K, Murakami A, Kanai A: A novel mutation of the TGFBI gene found in a Vietnamese family with atypical granular corneal dystrophy. Jpn J Ophthalmol 47:246-248, 2003. 27. Yamada T, Hayasaka S, Matsumoto M, Budu Esa T, Hayasaka Y, Endo M, Nagaki Y, Fujiki K, Murakami A, Kanai A: OPA1 gene mutations in Japanese patients with bilateral optic atrophy unassociated with mitochondrial DNA mutations at nt11778, 3460, and 14484. Jpn J Ophthalmol 47:409-411, 2003. 28. Zhang Y, Kimura T, Fujiki K, Sakuma H, Murakami A, Kanai A: Multiplex polymerase chain reaction for detection of herpes simplex virus type 1, type 2, cytomegalovirus, and varicella-zoster virus in ocular viral infections. Jpn J Ophthalmol 47:260-264, 2003. 29. Ha NT, Chau HM, Cung le X, Thanh TK, Fujiki K, Murakami A, Hiratsuka Y, Hasegawa N, Kanai A: Identification of novel mutations of the CHST6 gene in Vietnamese families affected with macular corneal dystrophy in two generations. Cornea 22:508-511, 2003. 30. Ha NT, Chau HM, Cung le X, Thanh TK, Fujiki K, Murakami A, Hiratsuka Y, Kanai A: Mutation analysis of the carbohydrate sulfotransferase gene in Vietnamese with macular corneal dystrophy. Invest Ophthalmol Vis Sci 44:3310-3316, 2003. 31. Iida-Hasegawa N, Furuhata A, Hayatsu H, Murakami A, Fujiki K, Nakayasu K, Kanai A: Mutations in the CHST6 gene in patients with macular corneal dystrophy: immunohistochemical evidence of heterogeneity. Invest Ophthalmol Vis Sci 44: 3272-3237, 2003 32. Yokoyama T, Nakatani S, Murakami A: A case of Kniest dysplasia with retinal detachment and the mutation analysis. Am J Ophthalmol 136:1186-1188, 2003 33. Chung LX, Ha NT, Chau HM, Thanh YK, Fujiki K, Murakami A, Hiratsuka Y, Kanai A: Mutation analysis of the TGFBI gene in Vietnamese with granular and Avellino corneal dystrophy Jpn J Ophthalmol 48:12-16.2004 34. Tian X, Fujiki K, Li Q, Murakami A, Xie P, Kanai A, Wang W, Liu Z: Compound heterozygous mutations of M1S1 gene in gelatinous droplike corneal dystrophy. Am J Ophthalmol 137:567-569, 2004 35. Kobayashi A, Fujiki K, Murakami A, Kato T, Chen LZ, Onoe H, Nakayasu K, Sakurai M, Takahashi M, Sugiyama K, Kanai A: Analysis of COL8A2 gene mutation in Japanese patients with Fuchs' endothelial dystrophy and posterior polymorphous dystrophy. Jpn J Ophthalmol 48:195-8, 2004. 36. Murakami A, Kimura S, Fujiki K, Fujimaki T, Kanai A: Mutations in Membrane Component, Chromosome 1, Surface Marker 1 (M1S1) gene in Gelatinous Drop-like Corneal Dystrophy. Jpn J Ophthalmol 48: 317-20,2004. 37. Ebihara N, Funaki T, Takai S, Miyazaki M, Fujiki K, Murakami A: Tear chymase in vernal keratoconjunctivitis. Curr Eye Res 28:417-420, 2004. 38. Ha NT, Nakayasu K, Murakami A, Ishidoh K, Kanai A: Microarray analysis identified differentially expressed genes in keratocytes from keratoconus patients. Curr Eye Res 28:373-9, 2004. 39. Fujimaki T, Huang ZY, Kitagawa H, Sakuma H, Murakami A, Kanai A, McLaren MJ, Inana G:Truncation and mutagenesis analysis of the human X-arrestin gene promoter. Gene 339:139-147.2004. 40. Funayama T, Ishikawa K, Ohtake Y, Tanino T, Kurosaka D, Kimura I, Suzuki K, IH, Nakamoto K, Yasuda N, Fujimaki T, Murakami A, Asaoka R, Hotta Y, Tanihara H, Kanamoto T, Mishima H, Fukuchi T, Abe H, Iwata T, Shimada N, Kudoh J, Shimizu N, Mashima Y: Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma. Invest Ophthalmol Vis Sci 45:4359-67, 2004. 41. Ishikawa K, Funayama T, Ohtake Y, Kimura I, Ideta H, Nakamoto K, Yasuda N, Fukuchi T, Fujimaki T, Murakami A, Asaoka R, Hotta Y, Kanamoto T, Tanihara H, Miyaki K, Mashima Y: Association between glaucoma and gene polymorphism of endothelin type A receptor. Mol Vis.11:431-7,2005. 42. Yokoyama T, Watanabe Y, Okisaka S, Murakami A: Macular hole secondary to epiretinal membrane in a juvenile patient. Am J Ophthalmol.139:357-359. 2005 43. Chen L, Kato T, Toshida H, Nakamura S, Murakami A: Immunohistochemical characterization of epithelial cells implanted in the flap-stroma interface of the cornea. Jpn J Ophthalmol 49:79-83, 2005. 44. Tian X, Fujiki K, Wang W, Murakami A, Xie P, Kanai A: Novel mutation (V505D) of the TGFBI gene found in a Chinese family with lattice corneal dystrophy, type I. Jpn J Ophthalmol 49:84-88, 2005. 45. Jin ZB, Liu XQ, Uchida A, Vervoort R, Morishita K, Hayakawa M, Murakami A, Matsumoto N, Niikawa N, Naoi N: Novel deletion spanning RCC1-like domain of RPGR in Japanese X-linked retinitis pigmentosa family. Mol Vis.11:535-41,2005 46. Ebihara N, Takai S, Miyazaki M, Murakami A: Mast cell chymase induces conjunctival epithelial cell apoptosis by a mechanism involving degradation of fibronectin. Curr Eye Res 30:429-35, 2005. 47. Ebihara N, Funaki T, Murakami A, Takai S, Miyazaki M: Mast cell chymase decreases the barrier function and inhibits the migration of corneal epithelial cells. Curr Eye Res 30:1061-1069, 2005. 48. Sato T, Uchida R, Tanigawa H, Uno K, Murakami A: Application of polymer gels containing side-chain phosphate groups to drug-delivery contact lenses. J. Appl Polym Sci: 98,731-735, 2005. 49. Lu W, Ebihara N, Miyazaki K, Murakami A: Reduced expression of laminin-5 in corneal epithelial cells under high glucose condition. Cornea 25:61-67, 2006. 50. Inagaki Y, Mashima Y, Funayama T, Ohtake Y, Fuse N, Yasuda N, Fukuchi T, Murakami A, Hotta Y: Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 13:1-7, 2006. 51. Yokoyama T, Fujiki K, Murakami A, Hotta Y: Long-term Follow-up of Two Sisters with Leber's Hereditary Optic Neuropathy. Jpn J Ophthalmol 50:78-80,2006. 52. Kanemoto M, Sato T, Aoyama A, Matsunaga T, Uno K, Toshida H, Murakami A: The interaction and compatibility between a soft contact lens and an ophthalmic drug. Eye Contact Lens 32 :192-6, 2006. 53. Inagaki Y, Mashima Y, Fuse N, Funayama T, Ohtake Y, Yasuda N, Murakami A, Hotta Y, Fukuchi T, Tsubota K: Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma Mol Vis.12:673-80, 2006. 54. Ebihara N, Nishikawa M, Murakami A: Disodium cromoglycate inhibits capsaicin-induced eosinophil infiltration of conjunctiva independent of mast cells. Jpn J Ophthalmol 50:205-10, 2006. 55. Jin ZB, Liu XQ, Hayakawa M, Murakami A, Naoi N: Mutational analysis of RPGR and RP2 genes in Japanese patients with retinitis pigmentosa: identification of four mutations Mol.Vis.12:1167-74,2006. 56. Funayama T, Mashima Y, Ohtake Y, Ishikawa K, Fuse N, Yasuda N, Fukuchi T, Murakami A, Hotta Y, Shimada N: SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma. Invest Ophthalmol Vis Sci.47:5368-75, 2006. 57. Takizawa Y, Hayashi S, Fujimaki T, Mizota A, Yokoyama T, Tanaka M, Murakami A: Central retinal vein occlusion caused by human herpesvirus 6. J Pediatr Ophthalmol Strabismus.43:176-8, 2006. 58. Ebihara N, Chen L, Tokura T, Ushio H, Iwatsu M, Murakami A: Distinct Functions between Toll-Like Receptors 3 and 9 in Retinal Pigment. Epithelial Cells. Ophthalmic Res.39:155-163, 2007. 59. Kubo SI, Iwatake A, Ebihara N, Murakami A, Hattori N: Visual impairment in Parkinson's disease treated with amantadine: Case report and review of the literature. Parkinsonism Relat Disord 14: 166-9, 2008. 60. Toshida H, Kogure N, Inoue N, Murakami. A: Trends in microbial keratitis in Japan. Eye Contact Lens 33:70-3, 2007. 61. Inoue N, Toshida H, Mamada N, Kogure N, Murakami A: Contact lens-induced infectious keratitis in Japan. Eye Contact Lens 33: 65-9, 2007. 62. Hiratsuka Y, Sasaki S, Nakatani S, Murakami A: Traumatic wound dehiscence after penetrating keratoplasty. Jpn J Ophthalmol51:146-7, 2007. 63. Ebihara N, Yamagami S, Yokoo S, Amano S, Murakami A: Involvement of C-C chemokine ligand 2-CCR2 interaction in monocyte-lineage cell recruitment of normal human corneal stroma. J Immunol 178:3288-92, 2007. 64. Ebihara N, Yamagami S, Chen L, Tokura T, Iwatsu M, Ushio H, Murakami A: Expression and function of toll-like receptor-3 and -9 in human corneal myofibroblasts. Invest Ophthalmol Vis Sci 48:3069-76. 2007. 65. Tian X, Fujiki K, Zhang Y, Murakami A, Li Q, Kanai A, Wang W, Hao Y, Ma Z: A novel variant lattice corneal dystrophy caused by association of mutation(V625D) in TGFBI gene. Am J Ophthalmol. 144:473-5,2007. 66. Kobayashi A, Fujiki K, Fujimaki T, Murakami A, Sugiyama K: In vivo laser confocal microscopic findings of corneal stromal dystrophies. Arch Ophthalmol. 125:1168-73, 2007. 67. Toshida H, Uesugi Y, Ebihara N, Murakami A: In Vivo Observations of a Case of Chlorpromazine Deposits in the Cornea Using an HRT II Rostock Corneal Module. Cornea. 26:1141-3,2007. 68. Toshida H, Nguyen DH, Beuerman RW, Murakami A: Evaluation of novel dry eye model: preganglionic parasympathetic denervation in rabbit. Invest Ophthalmol Vis Sci. 48:4468-75, 2007. 69. Kanemoto M, Toshida H, Takahiro I, Murakami A: Prosthetic soft contact lenses in Japan. Eye Contact Lens 33:300-3, 2007. 70. Nakatani S, Ebihara N, Murakami A: Stem cell factor in the tear fluid of vernal keratoconjunctivitis patients. Jpn J Ophthalmol.51:474-6, 2007. 71. Chen L, Ebihara N, Fujiki K, Murakami A: Expression and distribution of junctional adhesion molecule-1 in the human cornea. Jpn J Ophthalmol. 51:405-11, 2007. 72. Toshida H, Odaka A, Koike D, Murakami A: Effect of Retinol Palmitate Eye Drops on Experimental Keratoconjunctival Epithelial Damage Induced by n-Heptanol in Rabbit. Curr Eye Res. 33:13-8, 2008. 73. Funaki T, Ebihara N, Murakami A, Nakao A: Ex vivo transfer of Smad7 decreases damage to the corneal endothelium after penetrating keratoplasty. Jpn J Ophthalmol 52:204-10, 2008. 74. Seto T, Fujiki K, Kishishita H, Fujimaki T, Murakami A, Kanai A: A novel mutation in the cornea-specific keratin 12 gene in Meesmann corneal dystrophy. Jpn J Ophthalmol 52: 224-6, 2008. 75. Ebihara N, Funaki T, Matsuda H, Okumura K, Murakami A, Ra C: Corneal abnormalities in the NC/Nga mouse: an atopic dermatitis model Cornea.;27:923-9,2008. 76. ino Y, Fujimaki T, Fujiki K, Murakami A: A novel mutation (967-970+2)delAAAGGT in the choroideremia gene found in a Japanese family and related clinical findings. Jpn J Ophthalmol. 52:289-97, 2008. 77. Toshida H, Takahashi K, Sado K, Kanai A, Murakami A: Bifocal contact lenses: History, types, characteristics, and actual state and problems. Clin Ophthalmol 2:869-77,2008. 78. Toshida H, Nakayasu K, Murakami A: In vivo observation of rigid gas-permeable contact lens fragments embedded in cornea. Eye Contact Lens 35:105-7, 2009. 79. Toshida H, Nguyen D, Beuerman RW, Murakami A: Neurological evaluation of acute lacrimomimetic effect of Cyclosporine in an experimental rabbit dry eye model. Invest Ophthalmol Vis Sci 50: 2736-41, 2009. 80. Seto T, Takai T, Ebihara N, Matsuoka H, Wang XL, Ishii A, Ogawa H, Murakami A, Okumura K: LPI prevents cytokine release in mite protease-exposed conjunctival epithelial cells. Biochem Biophys Res Commun 379: 681-5, 2009. 81. Matsuda A, Okayama Y, Terai N, Yokoi N, Ebihara N, Tanioka H, Kawasaki S, Inatomi T, Katoh N, Ueda E, Hamuro J, Murakami A, Kinoshita S: The Role of Interleukin-33 in Chronic Allergic Conjunctivitis. Invest Ophthalmol Vis Sci 50:4646-52, 2009. 82. Toshida H, Murakami A: An atypical case of microcysts associated with silicone hydrogel contact lens: findings on in vivo confocal laser microscopy. Eye Contact Lens 35:156-8, 2009. 83. Kobayashi A, Fujiki K, Murakami A, Sugiyama K: In vivo laser confocal microscopy findings and mutational analysis for Schnyder's crystalline corneal dystrophy. Ophthalmology 116:1029-37,2009. 84. Ebihara N, Nakayama M, Tokura T, Ushio H, Murakami A.Expression and function of fibroblast growth factor-inducible 14 in human corneal myofibroblasts. Exp Eye Res 89:256-62,2009. 85. Ebihara N, Nakayama M, Tokura T, Iwatsu M, Ushio H, Murakami A. Proinflammatory effect of TWEAK/Fn14 interaction in human retinal pigment epithelial cells Curr Eye Res 34:836-4, 2009. 86. Sakuma K, Toshida H, Honda R, Tanaka K, Fukazawa A, Takahashi K, Suto C, Ebihara N, Murakami A:Effects of Topical Application of Ibudilast for Seasonal Allergic Conjunctivitis in Patients Wearing Soft Contact Lenses. Eye Contact Lens 35:251-4, 2009. 87. Himi M, Fujimaki T, Yokoyama T, Fujiki K, Takizawa T, Murakami A: A case of oculodentodigital dysplasia syndrome with novel GJA1 gene mutation. Jpn J Ophthalmol 53:541-5, 2009. 88. Ono K VisonnavongV, Konyama K, Hiratsuka Y, Murakami A: Geographical Distribution of Eye Health Professionals and Cataract Surgery in Lao PDR Ophthalmic Epidemiol 16: 354-61, 2009. 89. Watanabe Y, Hamanaka T, Takemura T, Murakami A. Involvement of platelet coagulation and inflammation in the endothelium of the Schlemm canal. Invest Ophthalmol Vis Sci 51: 277-283, 2010. 90. Matsuda A, Ebihara N, Yokoi N, Kawasaki S, Tanioka H, Inatomi T, de Waal Malefyt R, Hamuro J, Kinoshita S, Murakami A. Functional Roles of Thymic Stromal Lymphopoietin for Chronic Allergic Keratoconjunctivitis.Invest Ophthalmol Vis Sci 51:151-155, 2010. 91. Matsuda A, Ebihara N, Yokoi N, Okayama Y, Watanabe Y, Kawasaki S, Tanioka H, Walls AF, Hamuro J, Kinoshita S, Murakami A. Basophils in the giant papillae of chronic allergic keratoconjunctivitis. Br J Ophthalmol 94: 513-8,2010. 92. Ono K, Hiratsuka Y, Murakami A: Geographical distribution of ophthalmologists before and after the new postgraduate training program in Japan, Ophthalmic Epidemiol 17:125-30,2010. 93. Fukuoka H, Kawasaki S, Yamasaki K, Matsuda A, Fukumoto A, Murakami A, Kinoshita S.: Lattice Corneal Dystrophy Type IV (p.Leu527Arg) was Caused by a Founder Mutation of the TGFBI Gene in a Single Japanese Ancestor. Invest Ophthalmol Vis Sci.51:4523-30,2010. 94. Liu Z, Tian X, Iida, N,Fujiki Xie P Wang,W Ma Z, Kanai A, Murakami A.Mutation Analysis of CHST6 gene in Chinese Patients with Macular Corneal Dystrophy. Cornea 29:883-8,2010. 95. Ono K, Hiratsuka Y, Murakami A: Global Inequality in Eye Health. Am J Public Health 100:1784-8,2010. 96. Matsuda A, Murakami A:Lymphoid neogenesis in the giant papillae of patients with chronic allergic conjunctivitis" Journal of Allergy and Clinical Immunol.126:1310-2, 2010. 97. Ohtomo K, Ebihara N, Matsuda A, Tokura T, Funaki T, Murakami A: Role of TGF-β in tissue eosinophilia associated with vernal keratoconjunctivitis. Exp Eye Res.91:748-54, 2010. 98. Umeda Y, Nakamura S, Fujiki K, Toshida H, Saito A, Murakami A: Distribution of goblet cells and MUC5AC mRNA in the canine nictitating membrane. Exp Eye Res. Exp Eye Res 91:721-6, 2010. 99. Kobayakawa S, Hiratsuka Y, Watabe Y, Murakami A, Tochikubo T: Comparison of the influence of intracameral gentamicin, gatifloxacin, and moxifloxacin on the corneal endothelium in a rabbit model. Jpn J Ophthalmol 54:481-5, 2010. 100. Tano T, Hiratsuka Y, Ono K, Murakami A: Influence of cataract surgery and blood pressure changes caused by sodium restriction on retinal vascular diameter.Clinical Ophthalmology 4:1299–1309,2010 101. Marumoto T, Hiratsuka Y, Murakami A: The significance of the determination of lymphocytes with clinical manifestation of ophthalmic zoster sine herpete. Clin Ophthalmol.4:817-22, 2010. 102. Takihara Y, Inatani M, Seto T, Iwao K, Iwao M, Inoue T, Kasaoka N, Murakami A, Futa R, Tanihara H: Trabeculectomy with mitomycin C for open-angle glaucoma in phakic eyes vs pseudophakic eyes after phacoemulsification. Arch Ophthalmol 129:152-7, 2011. 103. Yamaguchi M, Ebihara N, Shima N, Kimoto M, Funaki T, Yokoo S, Murakami A, Yamagami S: Adhesion, migration, and proliferation of cultured human corneal endothelial cells by laminin-5. Invest Ophthalmol Vis Sci.52:679-84. 2011. 104. Kartasasmita A, Fujiki K, Iskandar E, Sovani I, Fujimaki T, Murakami A: A novel nonsense mutation in rhodopsin gene in two Indonesian families with autosomal recessive retinitis pigmentosa. Ophthalmic Genet 2:57-63, 2011. 105. Shinoda H, Koto T, Fujiki K, Murakami A, Tsubota K, Ozawa Y: Clinical findings in a choroideremia patient who underwent vitrectomy for retinal detachment associated with macular hole. Jpn J Ophthalmol 55:169-71, 2011. 106. Ishida Y, Yanai R, Sagara T, Nishida T, Toshida H, Murakami A: Decrease in intraocular pressure following orthokeratology measured with a noncontact tonometer. Jpn J Ophthalmol 55:190-5, 2011. 107. Ebihara N, Ohtomo K, Tokura T, Ushio H, Murakami A. Effect of Tacrolimus on Chemokine Production by Corneal Myofibroblasts via Toll-Like Receptors, Compared with Cyclosporine and Dexamethasone. Cornea. 30:702-8, 2011. 108. Hiratsuka Y, Yamada M, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T: Eye Care Comparative Effectiveness Research Team (ECCERT).Cost-effectiveness of cataract surgery in Japan. Jpn J Ophthalmol.55:333-42, 2011. 109. Ebihara N, Matsuda A, Nakamura S, Matsuda H, Murakami A: Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing. Invest Ophthalmol Vis Sci 52:8549-57, 2011. 110. Honda R, Toshida H, Suto C, Fujimaki T, Kimura T, Ohta T, Murakami A: Effect of long-term treatment with eyedrops for glaucoma on conjunctival bacterial flora. Infect Drug Resist 4:191-6, 2011. 111. Hamahata T, Fujimaki T, Fujiki K, Miyazaki A, Mizota A, Murakami A: OPA1 mutations in Japanese patients suspected to have autosomal dominant optic atrophy. Jpn J Ophthalmol 56:91-97, 2012 112. Sakanishi Y, Awano M, Mizota A, Tanaka M, Murakami A, Ohnuma K: Age-Related Changes in Spectral Transmittance of the Human Crystalline Lens in situ. Ophthalmologica 228:174-180, 2012. 113. Tamura K, Yokoyama T, Ebihara N, Murakami A:Histopathologic analysis of the internal limiting membrane surgically peeled from eyes with diffuse diabetic macular edema. Jpn J Ophthalmol 56:280-287, 2012. 114. Hori K, Matsuda A, Ebihara N, Imai K, Mori K, Funaki T, Watanabe Y, Nakatani S, Okada K, Matsuo O, Murakami A: Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts. Invest Ophthalmol Vis Sci. 53:1846-1851, 2012. 115. Uchida Y, Kudoh D, Murakami A, Honda M, Kitazawa S: Origins of superior dynamic visual acuity in baseball players: superior eye movements or superior image processing. PLoS One 7: e31530, 2012. 116. Toshida H, Kadota Y, Suto C, Ohta T, Murakami A: Multipurpose soft contact lens care in Japan. Clin Ophthalmol. 6:139-44, 2012. 117. Inomata T, Ebihara N, Funaki T, Matsuda A, Watanabe Y, Ning L, Xu Z, Murakami A, Arikawa-Hirasawa E: Perlecan-deficient mutation impairs corneal epithelial structure. Invest Ophthalmol Vis Sci 53:1277-84,2012. 118. Iwamoto S, Ebihara N, Hori K, Funaki T, Asada Y, Yokoi N, Inatomi T, Kawasaki S, Murakami A, Matsuda A: Filaggrin mutations are not associated with chronic allergic keratoconjunctivitis. Br J Ophthalmol. 96:1272-3, 2012. 119. Toshida H, Ohta T, Murakami A, Kobayashi A, Sugiyama K. Descemet stripping automated endothelial keratoplasty for microcornea. Jpn J Ophthalmol 56:436-40, 2012. 120. Toshida H, Tabuchi N, Koike D, Koide M, Sugiyama K, Nakayasu K, Kanai A, Murakami A: The effects of vitamin A compounds on hyaluronic acid released from cultured rabbit corneal epithelial cells and keratocytes. J Nutr Sci Vitaminol (Tokyo).;58:223-9, 2012. 121. Odaka A, Toshida H, Ohta T, Tabuchi N, Koike D, Suto C, Murakami A. Efficacy of retinol palmitate eye drops for dry eye in rabbits with lacrimal gland resection. Clin Ophthalmol.6:1585-93, 2012. 122. Amano K, Ishiguchi M, Aikawa T, Kimata M, Kishi N, Fujimaki T, Murakami A, Kogo M: Cleft lip in oculodentodigital dysplasia suggests novel roles for connexin43. J Dent Res.91(7 Suppl):38S-44S, 2012. 123. Yamamoto S, Sugawara T, Murakami A, Nakazawa M, Nao-I N, Machida S, Wada Y, Mashima Y, Miyake Y: Erratum to: Topical Isopropyl Unoprostone for Retinitis Pigmentosa: Microperimetric Results of the Phase 2 Clinical Study. Ophthalmol Ther 2:53, 2013. 124. Sasaki H, Takano T, Murakami A. Direct endoscopic probing for congenital lacrimal duct obstruction. Clin Experiment Ophthalmol 41:729-34, 2013. 125. Toshida H, Ohta T, Suto C, Murakami A. Effect of subconjunctival lacrimal gland transplantation in a rabbit dry eye model. Cornea 32 Suppl 1:S46-51, 2013. 126. Eye Care Comparative Effectiveness Research Team (ECCERT), Hiratsuka Y, Yamada M, Akune Y, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T: Cost-utility analysis of cataract surgery in Japan: a probabilistic Markov modeling study. Jpn J Ophthalmol 57:391-401, 2013. 127. Matsui A, Toshida H, Honda R, Seto T, Ohta T, Murakami A:Preoperative and postoperative optical coherence tomography findings in patients with rhegmatogenous retinal detachment involving the macular region. ISRN Ophthalmol 2013 Sep:426867,2013. doi: 10.1155/2013/426867. PMID: 24563793; PMCID: PMC3914191. 128. Kitazawa K, Kawasaki S, Shinomiya K, Aoi K, Matsuda A, Funaki T, Yamasaki K, Nakatsukasa M, Ebihara N, Murakami A, Hamuro J, Kinoshita S: Establishment of a human corneal epithelial cell line lacking the functional TACSTD2 gene as an in vitro model for gelatinous drop-like dystrophy. Invest Ophthalmol Vis Sci 54:5701-11, 2013. 129. Nakatani S, Murakami A: Descemet stripping automated endothelial keratoplasty for bullous keratopathy after anterior-posterior radial keratotomy. Cornea. 32:1179-82, 2013. 130. Toshida H, Honda R, Matsui A, Matsuzaki Y, Shimizu Y, Seto T, Ohta T, Murakami A: Double-glide method using Cathereep® protective sheet as a substitute in Descemet’s stripping automated endothelial keratoplasty. ISRN Transplantation. 2013 Article ID 713153, 2013. 131. Usui A, Mochizuki Y, Iida A, Miyauchi E, Satoh S, Sock E, Nakauchi H, Aburatani H, Murakami A, Wegner M, Watanabe S: The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells. Development 140:740-50, 2013. 132. Usui A, Iwagawa T, Mochizuki Y, Iida A, Wegner M, Murakami A, Watanabe S: Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinaldevelopment. FEBS Lett587:358-63, 2013. 133. Matsuzaki Y, Toshida H, Ohta T, Murakami A: A case of atypical mucin balls wearing extended wear of silicone hydrogel lens for therapeutic use. Case Rep Ophthalmol Med. 2013:167854, 2013. 134. Sasaki H, Takano T, Murakami A: Direct endoscopic probing for congenital lacrimal duct obstruction. Clin Experiment Ophthalmol. 7: 695-702, 2013. 135. Shimizu Y, Toshida H, Honda R, Matsui A, Ohta T, Asada Y, Murakami A: Prevalence of drug resistance and culture-positive rate among microorganisms isolated from patients with ocular infections over a 4-year period. Clin Ophthalmol.7:695-702, 2013. 136. Tano T, Ono K, Hiratsuka Y, Otani K, Sekiguchi M, Konno S, Kikuchi S, Onishi Y, Takegami M, Yamada M, Fukuhara S, Murakami A. Prevalence of pterygium in a population in Northern Japan: the Locomotive Syndrome and Health Outcome in Aizu Cohort Study. Acta Ophthalmol 91:e232-6, 2013. 137. Iwamoto S, Asada Y, Ebihara N, Hori K, Okayama Y, Kashiwakura J, Watanabe Y, Kawasaki S, Yokoi N, Inatomi T, Shinomiya K, Murakami A, Matsuda A: Interaction between conjunctival epithelial cells and mast cells induces CCL2 expression and piecemeal degranulation in mast cells. Invest Ophthalmol Vis Sci 54:2465-73, 2013. 138. Kasuga T, Chen YC, Bloomer MM, Hirabayashi KE, Hiratsuka Y, Murakami A, Lin SC: Trabecular meshwork length in men and women by histological assessment. Curr Eye Res 38:75-9, 2013. 139. Kobayashi H, Okamoto H, Murakami A, Iwata T: Plasma proteome analysis on cynomolgus monkey (macaca fascicularis) pedigrees with early onset drusen formation. Exp Anim. 63:305-10, 2014. 140. Hiratsuka Y, Yamada M, Akune Y, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T. Assessment of vision-related quality of life among patients with cataracts and the outcomes of cataract surgery using a newly developed visual function questionnaire: the VFQ-J11. Jpn J Ophthalmol 58:415-22, 2014. 141. Arai E, Fujimaki T, Yanagawa A, Fujiki K, Yokoyama T, Okumura A, Shimizu T, Murakami A: Familial cases of Norrie disease detected by copy number analysis. Jpn J Ophthalmol. 58:448-54, 2014. 142. Nakatani S, Murakami A: Three-year outcome of descemet stripping automated endothelial keratoplasty for bullous keratopathy after argon laser iridotomy. Cornea 33:780-4, 2014. 143. Mochizuki Y, Iida A, Lyons E, Kageyama R, Nakauchi H, Murakami A, Watanabe S. Use of cell type-specific transcriptome to identify genes specifically involved in Müller glia differentiation during retinal development. Dev Neurobiol 74:426-37, 2014. 144. Ohta T, Toshida H, Murakami A. Simplified and safe method of sutureless intrascleral posterior chamber intraocular lens fixation: Y-fixation technique. J Cataract Refract Surg. 40:2-7, 2014. 145. Asada Y, Ebihara N, Funaki T, Yokoi N, Murakami A, Matsuda A: Vernal keratoconjunctivitis with giant papillae on the inferior tarsal conjunctiva. Cornea. 33:32-4, 2014. 146. Inagaki K, Ohkoshi K, Ohde S, Deshpande GA, Ebihara N, Murakami A: Subthreshold Micropulse Photocoagulation for Persistent Macular Edema Secondary to Branch Retinal Vein Occlusion including Best-Corrected Visual Acuity Greater Than 20/40. J Ophthalmol 2014:251-7, 2014. 147. Iida A, Iwagawa T, Kuribayashi H, Satoh S, Mochizuki Y, Baba Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S: Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells. Proc Natl Acad Sci U S A 111:3751-6, 2014. 148. Suzuki T, Fujimaki T, Yanagawa A, Arai E, Fujiki K, Wada Y, Murakami A: A novel exon 17 deletion mutation of RPGRIP1 gene in two siblings with Leber congenital amaurosis. Jpn J Ophthalmol. 58:528-35, 2014. 149. Arai R, Kimura I, Imamura Y, Shinoda K, Matsumoto CS, Seki K, Ishida M, Murakami A, Mizota A: Photoreceptor inner and outer segment layer thickness in multiple evanescent white dot syndrome. Graefes Arch Clin Exp Ophthalmol. 252:1645-51, 2014. 150. Iida A, Iwagawa T, Baba Y, Satoh S, Mochizuki1 Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S: Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation. Dev Neurobiol. 75:947-960, 2015. 151. Inagaki K, Shuo T, Katakura K, Ebihara N, Murakami A, Ohkoshi K: Sublethal Photothermal Stimulation with a Micropulse Laser Induces Heat Shock Protein Expression in ARPE-19 Cells. J Ophthalmol. 2015:729792,2015. 152. Takakuwa K, Hamanaka T, Mori K, Chin S, Shinmei Y, Funaki T, Ebihara N, Ono K, Murakami A, Matsuda A: Atopic Glaucoma: Clinical and Pathophysiological Analysis. J Glaucoma 24:662-8, 2015. 153. Coppieters F, Todeschini AL, Fujimaki T, Baert A, De Bruyne M, Van Cauwenbergh C, Verdin H, Bauwens M, Ongenaert M, Kondo M, Meire F, Murakami A, Veitia RA, Leroy BP, De Baere E: Hidden Genetic Variation in LCA9-Associated Congenital Blindness Explained by 5'UTR Mutations and Copy-Number Variations of NMNAT1. Hum Mutat 36:1188-96, 2015. 154. Asada Y, Nakae S, Ishida W, Hori K, Sugita J, Sudo K, Fukuda K, Fukushima A, Suto H, Murakami A, Saito H, Ebihara N, Matsuda A: Roles of Epithelial Cell-Derived Type 2-Initiating Cytokines in Experimental Allergic Conjunctivitis.Invest Ophthalmol Vis Sci. 56:5194-202, 2015. 155. Kakigi C, Kasuga T, Wang SY, Singh K, Hiratsuka Y, Murakami A, Lin SC: Hypothyroidism and Glaucoma in The United States. PLoS One 10:e0133688, 2015. 156. Matsuda A, Asada Y, Takakuwa K, Sugita J, Murakami A, Ebihara N: DNA Methylation Analysis of Human Trabecular Meshwork Cells During Dexamethasone Stimulation. Invest Ophthalmol Vis Sci. 56:3801-9, 2015. 157. Arai E, Baba Y, Iwagawa T, Kuribayashi H, Mochizuki Y, Murakami A, Watanabe S: Ablation of Kcnj10 expression in retinal explants revealed pivotal roles for Kcnj10 in the proliferation and development of Müller glia. Mol Vis. 21:148-59, 2015. 158. Yamaguchi M, Shima N, Kimoto M, Ebihara N, Murakami A, Yamagami S: Markers for Distinguishing Cultured Human Corneal Endothelial Cells from Corneal Stromal Myofibroblasts. Curr Eye Res 40:1211-7, 2015. 159. Inagaki K, Ohkoshi K, Ohde S, Deshpande GA, Ebihara N, Murakami A: Comparative efficacy of pure yellow (577-nm) and 810-nm subthreshold micropulse laser photocoagulation combined with yellow (561-577-nm) direct photocoagulation for diabetic macular edema. Jpn J Ophthalmol 59: 21-28, 2015. 160. Nakano T, Kawashima M, Hiratsuka Y, Tamura H, Ono K, Murakami A, Tsubota K, Yamada M: Assessment of quality of life in patients with visual impairments using a new visual function questionnaire: the VFQ-J11. Clin Ophthalmol 10: 1939-44, 2016. 161. Tamaki K, Usui-Ouchi A, Murakami A, Ebihara N. Fibrocytes and Fibrovascular Membrane Formation in Proliferative Diabetic Retinopathy.Invest Ophthalmol Vis Sci. 57: 4999-5005, 2016. 162. Toride A, Toshida H, Matsui A, Matsuzaki Y, Honda R, Ohta T, Murakami A. Visual outcome after emergency surgery for open globe eye injury in Japan. Clin Ophthalmol 10: 1731-1736, 2016. 163. Shimazaki J, Maeda N, Hieda O, Ohashi Y, Murakami A, Nishida K, Tsubota K; Japan Pellucid Marginal Corneal Degeneration Study Group.National survey of pellucid marginal corneal degeneration in Japan. Jpn J Ophthalmol. 60:341-8, 2016. 164. Ueno K, Iwagawa T, Kuribayashi H, Baba Y, Nakauchi H, Murakami A, Nagasaki M, Suzuki Y, Watanabe S: Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation. Sci Rep.6:29264,2016. 165. Nakatani S, Murakami A: Descemet stripping automated endothelial keratoplasty using corneas from elderly donors. Graefes Arch Clin Exp Ophthalmol. 254:1135-40, 2016. 166. Yamaguchi M, Shima N, Kimoto M, Ebihara N, Murakami A, Yamagami S: Optimization of Cultured Human Corneal Endothelial Cell Sheet Transplantation and Post-Operative Sheet Evaluation in a Rabbit Model. Curr Eye Res. 41: 1178-1184, 2016. 167. Tano T, Ono K, Hiratsuka Y, Otani K, Sekiguchi M, Konno S, Kikuchi S, Onishi Y, Takegami M, Yamada M, Fukuhara S, Murakami A:Retinal vessel diameters in a Japanese population: the Locomotive Syndrome and Health Outcome in Aizu Cohort Study. Acta Ophthalmol 94: e432-441, 2016. 168. Kawashima M, Hiratsuka Y, Nakano T, Tamura H, Ono K, Murakami A, Inoue S, Tsubota K, Yamada M: The association between legal Japanese visual impairment grades and vision-related quality of life. Jpn J Ophthalmol. 60:219-25, 2016. 169. Toshida H, Funaki T, Ono K, Tabuchi N, Watanabe S, Seki T, Otake H, Kato T, Ebihara N, Murakami A: Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial. Drug Des Devel Ther11:1871-79, 2017. 170. Arai R, Usui-Ouchi A, Ito Y, Mashimo K, Murakami A, Ebihara N: Effects of Secreted Mast Cell Mediators on Retinal Pigment Epithelial Cells: Focus on Mast Cell Tryptase. Mediators Inflamm.2017:3124753,2017. 171. Iwamoto S, Koga T, Ohba M, Okuno T, Koike M, Murakami A, Matsuda A, Yokomizo T: Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B(4) receptor 2. Sci Rep 16:13267, 2017. 172. Inomata T, Ono K, Matsuba T, Shiang T, Di Zazzo A, Nakatani S, Yamaguchi M, Ebihara N, Murakami A: Pre-banking microbial contamination of donor conjunctiva and storage medium for penetrating keratoplasty. Jpn J Ophthalmol.61:369-77, 2017. 173. Iwatake A, Murakami A, Ebihara N: The expression of matrix metalloproteinases and their inhibitors in corneal fibroblasts by alarmins from necrotic corneal epithelial cells. Jpn J Ophthalmol. 62:92-100, 2017. 174. Kasuga T, Aruga F, Ono K, Hiratsuka Y, Murakami A: Visual impairment as an independent risk factor for falls in hospitalized patients. Can J Ophthalmol 52:559-63, 2017. 175. Inomata T, Shiang T, Iwagami M, Sakemi F, Fujimoto K, Okumura Y, Ohno M, Murakami A: Changes in Distribution of Dry Eye Disease by the New 2016 Diagnostic Criteria from the Asia Dry Eye Society. Sci Rep. 8:1918,2018 Erratum in: Sci Rep.8:10368, 2018. 176. Hamada M, Ohkoshi K, Inagaki K, Ebihara N, Murakami A: Visualization of microaneurysms using optical coherence tomography angiography: comparison of OCTA en face, OCT B-scan, OCT en face, FA, and IA images. Jpn J Ophthalmol. 62:168-75, 2018. 177. Takei M, Obana A, Inomata T, Tanaka T, Shiang T, Bae Y, Takemura T, Murakami A: Fundus changes in type III membranoproliferative glomerulonephritis: a case report. BMC Ophthalmol. 18:72, 2018. 178. Hamada M, Ohkoshi K, Inagaki K, Ebihara N, Murakami A. Subthreshold Photocoagulation Using Endpoint Management in the PASCAL® System for Diffuse Diabetic Macular Edema. J Ophthalmol 2018:7465794, 2018. 179. Inoue S, Kawashima M, Hiratsuka Y, Nakano T, Tamura H, Ono K, Murakami A, Tsubota K, Yamada M: Assessment of physical inactivity and locomotor dysfunction in adults with visual impairment. Sci Rep. 8:12032, 2018. 180. Kawamura Y, Suga A, Fujimaki T, Yoshitake K, Tsunoda K, Murakami A, Iwata T: LRRTM4-C538Y novel gene mutation is associated with hereditary macular degeneration with novel dysfunction of ON-type bipolar cells. J Hum Genet 63: 893-900, 2018. 181. Kuribayashi H, Baba Y, Iwagawa T, Arai E, Murakami A, Watanabe S: Roles of Nmnat1 in the survival of retinal progenitors through the regulation of proapoptotic gene expression via histone acetylation. Cell Death Dis 309:891, 2018. 182. Inomata T, Iwagami M, Hiratsuka Y, Fujimoto K, Okumura Y, Shiang T, Murakami A. Maximum blink interval is associated with tear film breakup time: A new simple, screening test for dry eye disease. Sci Rep 8:13443, 2108. 183. Nishino T, Kobayashi A, Mori N, Masaki T, Yokogawa H, Fujiki K, Yanagawa A, Murakami A, Sugiyama K: In vivo histology and p.L132V mutation in KRT12 gene in Japanese patients with Meesmann corneal dystrophy. Jpn J Ophthalmol 63:46-55, 2019. 184. Okumura Y, Inomata T, Iwagami M, Eguchi A, Mizuno J, Shiang T, Kawasaki S, Shimada A, Inada E, Amano A, Murakami A: Shortened cataract surgery by standardisation of the perioperative protocol according to the Joint Commission International accreditation: a retrospective observational study. BMJ Open. 9: e028656, 2019. 185. Nikopoulos K, Cisarova K, Quinodoz M, Koskiniemi-Kuendig H, Miyake N,Farinelli P, Rehman AU, Khan MI, Prunotto A, Akiyama M, Kamatani Y, Terao C, MiyaF, Ikeda Y, Ueno S, Fuse N, Murakami A, Wada Y, Terasaki H, Sonoda KH, Ishibashi T, Kubo M, Cremers FPM, Kutalik Z, Matsumoto N, Nishiguchi KM, Nakazawa T,Rivolta C. A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy. Nat Commun 10:2884, 2019. 186. Koyanagi Y, Akiyama M, Nishiguchi KM, Momozawa Y, Kamatani Y, Takata S, Inai C, Iwasaki Y, Kumano M, Murakami Y, Omodaka K, Abe T, Komori S, Gao D, Hirakata T, Kurata K, Hosono K, Ueno S, Hotta Y, Murakami A, Terasaki H, Wada Y, Nakazawa T, Ishibashi T, Ikeda Y, Kubo M, Sonoda KH: Genetic characteristics of retinitis pigmentosa in 1204 Japanese patients. J Med Genet 56:662-70, 2019. 187. Nishiguchi KM, Ikeda Y, Fujita K, Kunikata H, Akiho M, Hashimoto K, Hosono K, Kurata K, Koyanagi Y, Akiyama M, Suzuki T, Kawasaki R, Wada Y, Hotta Y, SonodaKH, Murakami A, Nakazawa M, Nakazawa T, Abe T: Phenotypic Features of Oguchi Disease and Retinitis Pigmentosa in Patients with S-Antigen Mutations: A Long-Term Follow-up Study. Ophthalmology 126:155-66, 2019. 188. Okumura Y, Inomata T, Miyamoto S, Nakatani S, Hiratsuka Y, Yamaguchi M, Iwamoto S, Murakami A. Donor characteristics and risk factors for methicillin-resistant Staphy lococcus aureus contamination in storage medium for corneal transplantation: A 10-year retrospective study. Transpl Infect Dis 126: e13123, 2019. 189. Hirakata T, Lee HC, Ohba M, Saeki K, Okuno T, Murakami A, Matsuda A, YokomizoT: Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating T(h)2 immune responses. FASEB J 33:3392-3403, 2019. 190. Honda R, Kasuga T, Murakami A, Matsuda A: Effects of the Numbers and the Shapes of Venting Slits on Intraocular Pressure after Baerveldt Glaucoma Drainage Implant. Curr Eye Res 44:921-4, 2019. 191. Miyagawa Y, Murakami A, Ebihara N: The proteolytic effect of mast cell tryptase to eotaxin-1/CCL11·eotaxin-2/CCL24 and eotaxin-3/CCL26 produced by conjunctival fibroblasts. Jpn J Ophthalmol 63:215-20, 2019. 192. Inomata T, Nakamura M, Iwagami M, Shiang T, Yoshimura Y, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Hori S, Hiratsuka Y, Uchino M, Tsubota K, Dana R, Murakami A: Risk Factors for Severe Dry Eye Disease: Crowdsourced Research Using DryEyeRhythm. Ophthalmology 126:766-8, 2019. 193. Sadamatsu Y, Hiratsuka Y, MichihataN, Jo T, Matsui H, Murakami A, Fushimi K, Yasunaga H: Activity of daily living improvement after cataract surgery for patients in nursing care facilities. Annals of Clinical Epidemiology 1:80-85, 2019. 194. Iwagawa T, Aihara Y, Umutoni D, Baba Y, Murakami A, Miyado K, Watanabe S: Cd9 Protects Photoreceptors from Injury and Potentiates Edn2 Expression. Invest Ophthalmol Vis Sci. 2020 Mar 9;61(3):7. doi: 10.1167/iovs.61.3.7. PubMed PMID:32150249. 195. Inomata T, Iwagami M, Nakamura M, Shiang T, Fujimoto K, Okumura Y, Iwata N,Fujio K, Hiratsuka Y, Hori S, Tsubota K, Dana R, Murakami A: Association between dry eye and depressive symptoms: Large-scale crowdsourced research using the DryEyeRhythm iPhone application. Ocul Surf 18:312-319, 2020. 196. Nishiguchi KM, Kunikata H, Fujita K, Hashimoto K, Koyanagi Y, Akiyama M, IkedaY, Momozawa Y, Sonoda KH, Murakami A, Wada Y, Nakazawa T: Association of CRX phenotypes and retinal phenotypes confounded by variable expressivity and electronegative electroretinogram. Clin Exp Ophthalmol 48:644-657, 2020. 197. Fujimoto K, Inomata T, Okumura Y, Iwata N, Fujio K, Eguchi A, Nagino K, Shokirova H, Karasawa M, Murakami A: Comparison of corneal thickness in patients with dry eye disease using the Pentacam rotating Scheimpflug camera and anterior segment optical coherence tomography. PLoS One 15: e0228567, 2020. 198. Yoshida Y, Hiratsuka Y, Kawachi I, Murakami A, Kondo K, Aida J: Association　between visual status and social participation in older Japanese: The JAGES　cross-sectional study. Soc Sci Med 253:112959, 2020. 199. Inomata T, Nakamura M, Iwagami M, Midorikawa-Inomata A, Okumura Y, Fujimoto K, Iwata N, Eguchi A, Shokirova H, Miura M, Fujio K, Nagino K, Nojiri S, Murakami A: Comparing the Japanese Version of the Ocular Surface Disease Index and Dry Eye-Related Quality-of-Life Score for Dry Eye Symptom Assessment. Diagnostics (Basel) 10: 203, 2020. 200. Koiwa C, Nakatani S, Inomata T, Yamaguchi M, Iwamoto S, Murakami A: Multiple　excimer laser phototherapeutic keratectomies for Avellino corneal dystrophy: a case report. Int J Ophthalmol 13: 841-844, 2020. 201. Inomata T, Nakamura M, Iwagami M, Midorikawa-Inomata A, Sung J, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Fujio K, Nagino K, Hori S, Tsubota K, Dana R, Murakami A: Stratification of Individual Symptoms of Contact Lens-Associated Dry Eye Using the iPhone App DryEyeRhythm: Crowdsourced Cross-Sectional Study. J Med Internet Res 22:e18996,2020. doi: 10.2196/18996.PMID: 32589162 202. Kabashima K, Murakami A, Ebihara N: Effects of Benzalkonium Chloride and Preservative-Free Composition on the Corneal Epithelium Cells. J Ocul Pharmacol Ther 10:10,2019. 203. Inomata T, Sung J, Nakamura M, Fujisawa K, Muto K, Ebihara N, Iwagami M, Nakamura M, Fujio K, Okumura Y, Okano M, Murakami A: New medical big data for P4 medicine on allergic conjunctivitis. Allergol Int 69:510-518.2020. 204. Inomata T, Kitazawa K, Kuno T, Sung J, Nakamura M, Iwagami M, Takagi H, Midorikawa-Inomata A, Zhu J, Fujimoto K, Okumura Y, Miura M, Fujio K, Hirosawa K, Akasaki Y, Kuwahara M, Dana R, Murakami A: Clinical and Prodromal Ocular Symptoms in Coronavirus Disease: A Systematic Review and Meta-Analysis. Invest Ophthalmol Vis Sci 61:29, 2020 205. Hirosawa K, Inomata T, Sung J, Nakamura M, Okumura Y, Midorikawa-Inomata A, Miura M, Fujio K, Akasaki Y, Fujimoto K, Zhu J, Eguchi A, Nagino K, Kuwahara M, Shokirova H, Yanagawa A, Murakami A. Diagnostic ability of maximum blink interval together with Japanese version of Ocular Surface Disease Index score for dry eye disease. Sci Rep 10:18106, 2020. 206. Hayashi T, Kameya S, Mizobuchi K, Kubota D, Kikuchi S, Yoshitake K, Mizota A, Murakami A, Iwata T, Nakano T: Genetic defects of CHM and visual acuity outcome in 24 choroideremia patients from 16 Japanese families. Sci Rep10:15883, 2020. 207. Inomata T, Sung J, Nakamura M, Iwagami M, Okumura Y, Iwata N, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Nagino K, Fujio K, Miura M, Shokirova H, Murakami A: Using Medical Big Data to Develop Personalized Medicine for Dry Eye Disease. Cornea 39 (Suppl 1):S39-S46, 2020 208. Inomata T, Fujimoto K, Okumura Y, Zhu J, Fujio K, Shokirova H, Miura M, Okano M, Funaki T, Sung J, Negishi N, Murakami A: Novel immunotherapeutic effects of topically administered ripasudil (K-115) on corneal allograft survival. Sci Rep 10:19817, 2020. 209. Hirakata T, Fujinami K, Saito W, Kanda A, Hirakata A, Ishida S, Murakami A, Tsunoda K, Miyake Y: Acute unilateral inner retinal dysfunction with photophobia: importance of electrodiagnosis. Jpn J Ophthalmol 65:42-53, 2020. 210. Eguchi A, Inomata T, Nakamura M, Nagino K, Iwagami M, Sung J, Midorikawa-Inomata A, Okumura Y, Fujio K, Fujimoto K, Miura M, Akasaki Y, Shokirova H, Hirosawa K, Kuwahara M, Zhu J, Dana R, Murakami A, Kobayashi H: Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application. Jpn J Ophthalmol 65: 42-53. 2021. 211. Mashimo K, Usui-Ouchi A, Ito Y, Wakasa-Arai R, Yokoi N, Kawasaki S, Murakami A, Matsuda A, Ebihara N: Role of oncostatin M in the pathogenesis of vernal keratoconjunctivitis: focus on tissue remodeling. Jpn J Ophthalmol 65:144-153, 2021. 212. Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Sato K, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda KH, Rivolta C, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T: A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa. Commun Biol 4:140,2021. 213. Kudo D, Hiratsuka Y, Nakamura M, Uchida Y, Ono S, Murakami A: Optimal methods for estimating sports vision in kendo athletes. Sci Rep 11:315, 2021. 214. Koyanagi Y, Akiyama M, Nishiguchi KM, Momozawa Y, Kamatani Y, Takata S, Inai C, Iwasaki Y, Kumano M, Murakami Y, Komori S, Gao D, Kurata K, Hosono K, Ueno S, Hotta Y, Murakami A, Terasaki H, Wada Y, Nakazawa T, Ishibashi T, Ikeda Y, Kubo M, Sonoda KH: Regional differences in genes and variants causing retinitis pigmentosa in Japan. Jpn J Ophthalmol 65:338-343, 2021. 215. Kimura M, Ando T, Kume Y, Fukase S, Matsuzawa M, Kashiwagi K, Izawa K, Kaitani A, Nakano N, Maeda K, Ogawa H, Okumura K, Nakao S, Murakami A, Ebihara N, Kitaura J. A nerve-goblet cell association promotes allergic conjunctivitis through rapid antigen passage. JCI Insight 8:e168596,2023. 216. Inomata T, Sung J, Nakamura M, Iwagami M, Akasaki Y, Fujio K, Nakamura M, Ebihara N, Ide T, Nagao M, Okumura Y, Nagino K, Fujimoto K, Eguchi A, Hirosawa K, Midorikawa Inomata A, Muto K, Fujisawa K, Kikuchi Y, Nojiri S, Murakami A: Using the AllerSearch Smartphone App to Assess the Association Between Dry Eye and Hay Fever: mHealth-Based Cross-Sectional Study. J Med Internet Res 25: e38481,2023. 217. Fujio K, Nagino K, Huang T, Sung J, Akasaki Y, Okumura Y, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Miura M, Hurramhon S, Yee A, Hirosawa K, Ohno M, Morooka Y, Murakami A, Kobayashi H, Inomata T: Clinical utility of maximum blink interval measured by smartphone application DryEyeRhythm to support dry eye disease diagnosis. Sci Rep 13:13583, 2023. 218. Nagino K, Okumura Y, Akasaki Y, Fujio K, Huang T, Sung J, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Hurramhon S, Yee A, Miura M, Ohno M, Hirosawa K, Morooka Y, Murakami A, Kobayashi H, Inomata T: Smartphone App-Based and Paper-Based Patient-Reported Outcomes Using a Disease-Specific Questionnaire for Dry Eye Disease: Randomized Crossover Equivalence Study. J Med Internet Res 25:e42638, 2023. 219. Nagino K, Inomata T, Nakamura M, Sung J, Midorikawa-Inomata A, Iwagami M, Fujio K, Akasaki Y, Okumura Y, Huang T, Fujimoto K, Eguchi A, Miura M, Hurramhon S, Zhu J, Ohno M, Hirosawa K, Morooka Y, Dana R, Murakami A, Kobayashi H. Symptom-based stratification algorithm for heterogeneous symptoms of dry eye disease: a feasibility study. Eye (Lond) 37: 3484-3491, 2023. 220. Watanabe K, Hiratsuka Y, Yamamoto S, Murakami A: Economic Impacts and Quality of Life for Caregivers of Patients with Retinitis Pigmentosa: A Cross-Sectional Japanese Study. Healthcare (Basel) 11: 988, 2023. 221. Watanabe K, Aouadj C, Hiratsuka Y, Yamamoto S, Murakami A. Quality of Life and Economic Impacts of Retinitis Pigmentosa on Japanese Patients: A Non-interventional Cross-sectional Study. Adv Ther 40: 2375-2393, 2023. 222. Matsuzawa M, Ando T, Fukase S, Kimura M, Kume Y, Ide T, Izawa K, Kaitani A, Hara M, Nakamura E, Kamei A, Matsuda A, Nakano N, Maeda K, Tada N, Ogawa H, Okumura K, Murakami A, Ebihara N, Kitaura J: The protective role of conjunctival goblet cell mucin sialylation. Nat Commun 14:1417,2023. 223. Inomata T, Sung J, Fujio K, Nakamura M, Akasaki Y, Nagino K, Okumura Y, Iwagami M, Fujimoto K, Ebihara N, Nakamura M, Midorikawa-Inomata A, Shokirova H, Huang T, Hirosawa K, Miura M, Ohno M, Morooka Y, Iwata N, Iwasaki Y, Murakami A: Individual multidisciplinary clinical phenotypes of nasal and ocular symptoms in hay fever: Crowdsourced cross-sectional study using AllerSearch. Allergol Int 72: 418-427, 2023. 224. Nishijima E, Honda S, Kitamura Y, Namekata K, Kimura A, Guo X, Azuchi Y, Harada C, Murakami A, Matsuda A, Nakano T, Parada LF, Harada T: Vision protection and robust axon regeneration in glaucoma models by membrane- associated Trk receptors. Mol Ther 31:810-24, 2023. 225. Fujio K, Sung J, Hirosawa K, Yamaguchi M, Toshida H, Inagaki K, Ishida G,Itoi M, Sado K, Hayatsu H, Nobutaka H, Ono J, Taniguchi H, Iwagami M, Nagino K, Okumura Y, Midorikawa-Inomata A, Akasaki Y, Huang T, Morooka Y, Okuyama T, Nakao S, Murakami A, Kobayashi H, Inomata T: Effect of antihistamine-releasing contact lenses on ocular symptoms and treatment behavior in patients with seasonal allergic conjunctivitis: A retrospective study. Heliyon 10: e33385, 2024. 226. Goto K, Koyanagi Y, Akiyama M, Murakami Y, Fukushima M, Fujiwara K, Iijima H, Yamaguchi M, Endo M, Hashimoto K, Ishizu M, Hirakata T, Mizobuchi K, Takayama M, Ota J, Sajiki AF, Kominami T, Ushida H, Fujita K, Kaneko H, Ueno S, Hayashi T, Terao C, Hotta Y, Murakami A, Kuniyoshi K, Kusaka S, Wada Y, Abe T, Nakazawa T, Ikeda Y, Momozawa Y, Sonoda KH, Nishiguchi KM: Disease-specific variant interpretation highlighted the genetic findings in 2325 Japanese patients with retinitis pigmentosa and allied diseases. J Med Genet 61: 613-20, 2024. 227. Ari Widjaja S, Mieler WF, Sasono W, Soelistijo SA, Kartasasmita AS, Murakami A, Nakao S: Retinal neurovascular alteration in type 2 diabetes with renal impairment in association with systemic arterial stiffness. Int J Retina Vitreous 10:2, 2024. 228. Akasaki Y, Iwagami M, Sung J, Nagino K, Adachi T, Morita H, Tamari M, Kainuma K, Kan-O K, Ogata H, Sakashita M, Futamura M, Kurashima Y, Nakajima S, Masaki K,Ogawa Y, Sato S, Miyagawa A, Midorikawa-Inomata A, Fujimoto K, Okumura Y, Fujio K, Huang T, Hirosawa K, Morooka Y, Nakao S, Murakami A, Kobayashi H, Inomata T.Impact of COVID-19 on care-seeking patterns for hay fever in Japan: A retrospective claims database cohort study. Allergy 79:1056-1060, 2024 229. Hirosawa K, Inomata T, Akasaki Y, Sung J, Yee A, Iwagami M, Nagino K, Okumura Y, Fujimoto K, Midorikawa-Inomata A, Eguchi A, Shokirova H, Fujio K, Huang T, Morooka Y, Kobayashi H, Murakami A, Nakao S. Impact of the Coronavirus Disease 2019 Pandemic on Outpatient Visits for Diabetic Retinopathy in Japan: A Retrospective Cohort Study. Transl Vis Sci Technol. 2024 Sep 3;13(9):6. doi: 10.1167/tvst.13.9.6. PMID: 39235400; PMCID: PMC11379092. 230,Kuribayashi H, Iwagawa T, Murakami A, Kawamura T, Suzuki Y, Watanabe S. NMNAT1 Is Essential for Human iPS Cell Differentiation to the Retinal Lineage. Invest Ophthalmol Vis Sci. 2024 Oct 1;65(12):37. doi: 10.1167/iovs.65.12.37. PMID: 39446354; PMCID: PMC11512567 英文総説 1.Jin ZB, Hayakawa M, Murakami A, Nao-i N. RCC1-like domain and ORF15: essentials in RPGR gene. Adv Exp Med Biol. 2006;572:29-33. doi: 10.1007/0-387-32442-9_5. PMID: 17249551. 2.Hiratsuka Y, Ono K, Murakami A. Alcohol use and cataract Curr Drug Abuse Rev.;2(3):226-9,2009 3.Murakami　A . Autonomic Nerve Dysfunction in Ocular Diseases. Juntendo Medical Journal 62 377-380, 2016 4.Inomata T, Sung J, Nakamura M, Fujisawa K, Muto K, Ebihara N, Iwagami M, Nakamura M, Fujio K, Okumura Y, Okano M, Murakami A. New medical big data for P4 medicine on allergic conjunctivitis. Allergol Int. 2020 Jul 7:S1323-8930(20)30089-7. doi: 10.1016/j.alit.2020.06.001. Epub ahead of print. PMID: 32651122 5.Okumura Y, Inomata T, Iwata N, Sung J, Fujimoto K, Fujio K, Midorikawa-Inomata A, Miura M, Akasaki Y, Murakami A. A Review of Dry Eye Questionnaires: Measuring Patient-Reported Outcomes and Health-Related Quality of Life. Diagnostics (Basel). 2020 Aug 5;10(8):E559. doi:

研究テーマ

失明予防, 網膜色素変性、遺伝学

研究業績（論文）

1. Murakami A, Konomi H, Itokazu N, Arima M, Sakuragawa N, Nakajima A, Tanaka M, Tajima S, Hayashi T, Kino J: Partial characterization of an　usual 185kDa protein synthesized by dermal fibroblasts from patients with Marfan syndrome. J Biochem 106: 490-494,1989.
2. Mashima Y, Murakami A, Welber R, Kennaway N, Clarke L, Shiono T, Inana G: Nonsense-codon mutation of the ornithine aminotransferase gene with decreased level of mutant mRNA in Gyrate Atrophy. Am J Hum Genet. 51:81-91, 1992.
3. Akaki Y, Hotta Y, Mashima Y, Murakami A, Kennaway N, Welber R, Inana G: A deletion in the ornithine aminotransferase gene in the gyrate atrophy. J Biol Chem 267: 12950-12954, 1992.
4. Murakami A, Yajima T, Inana G: Isolation of human retinal genes: recoverin cDNA and gene. Biochem Biophys Res Commun. 187: 234-244, 1992.
5. Murakami A, Yajima T, Sakuma H, Mclaren M, Inana G: X-arrestin: a new retinal arrestin mapping to the X chromosome. FEBS Letters. 334: 203-209, 1993.
6. Fujiki K, Hotta Y, Murakami A, Yoshii M, Hayakawa M, Ichikawa T, Takeda M, Akeo K, Okisaka S, Kanai A: Missense mutation of rhodopsin gene codon 15 found in Japanese autosomal dominant retinitis pigmentosa. Jpn J Hum Genet. 40: 271-277, 1995.
7. Sakuma H, Inana G, Murakami A, Yajima T, Welber R, Murphey W, Gass D, Hotta Y, Hayakawa M, Fujiki K, Gao YQ, Danciger M, Farber D, Cideciyan A, Jacobson S: A heterozygous putative null mutation in ROM1 without a mutation in Peripherin/RDS in a family with retinitis pigmentosa. Genomics 27: 384-386, 1995.
8. Higashide T, Murakami A, McLaren M, Inana G: Cloning of the cDNA for a novel photoreceptor protein. J Biol Chem 271: 1797-1804, 1996.
9. Sakuma H, Inana G, Murakami A, Higashide T, McLaren M: Immunolocalization of X-arrestin in human cone photoreceptor: FEBS Letters. 382: 105-110, 1996.
10. Parminder A, Murakami A, Inana G, Berson E, Dryja T: Evaluation of the human gene encoding recoverin in patients with retinitis pigmentosa or an allied disease. Invest Ophthalmol Vis Sci 388: 704-709,1997.
11. Okisaka S, Murakami A, Mizukawa A, Ito J: Apoptosis in retinal ganglion cell decrease in human glaucomatous eyes. Jpn J Ophthalmol 41: 84-88, 1997.
12. Yoshii M, Murakami A, Akeo K, Fujiki K，Saga M, Mizukawa A, Itoh J, Okisaka S, Yanashima K, Hotta Y, Kanai A, Oguchi Y: Visual function in retinitis pigmentosa related to a codon 15 rhodopsin gene mutation. Ophthalmic Res 30: 1-10, 1998.
13. Yoshii M, Murakami A, Akeo K, Nakamura A, Shimoyama M, Ikeda Y, Kikuchi Y, Okisaka S, Yanashima K, Oguchi Y: Visual function and gene analysis in a family with Oguchi’s disease. Ophthalmic Res 30: 394-401,1998.
14. Sakuma H, Murakami A, Fujimaki T, Inana G: Isolation and characterization of the human X-arrestin gene. Gene 224: 87-95, 1998.
15. Nakagami T, Murakami A, Okisaka S, Ebihara N: Mast cells in pterygium: Number and phenotype. Jpn J Ophthalmol 43: 75-79, 1999.
16. Fujiki K, Hotta Y, Hayakawa M, Saito A, Mashima Y, Mori M, Yoshii M, Murakami A, Matsumoto M, Hayasaka S, Tagami N, Isashiki Y, Ohba N, Kanai A: REP-1 gene mutations in Japanese patients with choroideremia. Graefe’s Arch Clin Exp Ophthalmol 237: 735-740, 1999.
17. Maeda T, Ohguro H, Sohma H, Kuroki Y, Wada H, Okisaka S, Murakami A: Purification and characterization of bovine cone arrestin(cArr). FEBS Lett. 470: 336-340, 2000.
18. Nakagami T, Watanabe I, Murakami A, Okisaka S, Ebihara N: Expression of stem cell factor in pterygium. Jpn J Ophthalmol 44:193-197, 2000.
19. Karasawa Y, Murakami A, Okisaka S: Apoptosis after butyrate-induced differentiation in retinoblastoma cell line Y-79. Jpn J Ophthalmol 44:601-609, 2000.
20. Murakami A, Fujiki K, Hasegawa S, Imamura S, Kawano H, Kanai A, Matsumoto M: Transthyretin Ser-44 mutation in a case with vitreous amyloidosis. Am J Ophthalmol 133: 272-273, 2002.
21. Ha NT, Murakami A, Fujiki K, Kanai A: Transferrin-polyethylenimine conjugate, FuGENE6, and TransIT-LT as non-viral vectors for gene transfer to the corneal endothelium. Jpn J Ophthalmol 46: 140-146, 2002.
22. Takahashi K, Takahashi K, Murakami A, Okisaka S, Kimura T, Kanai A: Heterozygous Ala137Pro mutation in keratin 12 gene found in Japanese Meesmann’s corneal dystrophy. Jpn J Ophthalmol 46:673-674, 2002.
23. Ha NT, Chau HM, Cung LX, Thanh TK, Fujiki K, Murakami A, Kanai A: A novel mutation of M1S1 gene found in a Vietnamese patient with gelatinous droplike corneal dystrophy. Am J Ophthalmol 135:391-392, 2003.
24. Chau HM, Ha NT, Cung LX, Thanh TK, Fujiki K, Murakami A, Kanai A:H626R and R124C mutations of the TGFB1(BIGH3) gene caused lattice corneal dystrophy in Vietnamese people. Br J Ophthalmol 87:686-689, 2003.
25. Zhang Y, Kimura T, Fujiki K, Sakuma H, Murakami A, Kanai A: Multiples polymerase chain reaction for detection of herpes simplex virus Type 1, Type 2, Cytomegalovirus, and Varicella-Zoster virus in ocular viral infections. Jpn J Ophthalmol 47:260-264, 2003.
26. Ha NT, Cung LX, Chau HM, Thanh TK, Fujiki K, Murakami A, Kanai A: A novel mutation of the TGFBI gene found in a Vietnamese family with atypical granular corneal dystrophy. Jpn J Ophthalmol 47:246-248, 2003.
27. Yamada T, Hayasaka S, Matsumoto M, Budu Esa T, Hayasaka Y, Endo M, Nagaki Y, Fujiki K, Murakami A, Kanai A: OPA1 gene mutations in Japanese patients with bilateral optic atrophy unassociated with mitochondrial DNA mutations at nt11778, 3460, and 14484. Jpn J Ophthalmol 47:409-411, 2003.
28. Zhang Y, Kimura T, Fujiki K, Sakuma H, Murakami A, Kanai A: Multiplex polymerase chain reaction for detection of herpes simplex virus type 1, type 2, cytomegalovirus, and varicella-zoster virus in ocular viral infections. Jpn J Ophthalmol 47:260-264, 2003.
29. Ha NT, Chau HM, Cung le X, Thanh TK, Fujiki K, Murakami A, Hiratsuka Y, Hasegawa N, Kanai A: Identification of novel mutations of the CHST6 gene in Vietnamese families affected with macular corneal dystrophy in two generations. Cornea 22:508-511, 2003.
30. Ha NT, Chau HM, Cung le X, Thanh TK, Fujiki K, Murakami A, Hiratsuka Y, Kanai A: Mutation analysis of the carbohydrate sulfotransferase gene in Vietnamese with macular corneal dystrophy. Invest Ophthalmol Vis Sci 44:3310-3316, 2003.
31. Iida-Hasegawa N, Furuhata A, Hayatsu H, Murakami A, Fujiki K, Nakayasu K, Kanai A: Mutations in the CHST6 gene in patients with macular corneal dystrophy: immunohistochemical evidence of heterogeneity. Invest Ophthalmol Vis Sci 44: 3272-3237, 2003
32. Yokoyama T, Nakatani S, Murakami A: A case of Kniest dysplasia with retinal detachment and the mutation analysis. Am J Ophthalmol 136:1186-1188, 2003
33. Chung LX, Ha NT, Chau HM, Thanh YK, Fujiki K, Murakami A, Hiratsuka Y, Kanai A: Mutation analysis of the TGFBI gene in Vietnamese with granular and Avellino corneal dystrophy Jpn J Ophthalmol 48:12-16.2004
34. Tian X, Fujiki K, Li Q, Murakami A, Xie P, Kanai A, Wang W, Liu Z: Compound heterozygous mutations of M1S1 gene in gelatinous droplike corneal dystrophy. Am J Ophthalmol 137:567-569, 2004
35. Kobayashi A, Fujiki K, Murakami A, Kato T, Chen LZ, Onoe H, Nakayasu K, Sakurai M, Takahashi M, Sugiyama K, Kanai A: Analysis of COL8A2 gene mutation in Japanese patients with Fuchs' endothelial dystrophy and posterior polymorphous dystrophy. Jpn J Ophthalmol 48:195-8, 2004.
36. Murakami A, Kimura S, Fujiki K, Fujimaki T, Kanai A: Mutations in Membrane Component, Chromosome 1, Surface Marker 1 (M1S1) gene in Gelatinous Drop-like Corneal Dystrophy. Jpn J Ophthalmol 48: 317-20,2004.
37. Ebihara N, Funaki T, Takai S, Miyazaki M, Fujiki K, Murakami A: Tear chymase in vernal keratoconjunctivitis. Curr Eye Res 28:417-420, 2004.
38. Ha NT, Nakayasu K, Murakami A, Ishidoh K, Kanai A: Microarray analysis identified differentially expressed genes in keratocytes from keratoconus patients. Curr Eye Res 28:373-9, 2004.
39. Fujimaki T, Huang ZY, Kitagawa H, Sakuma H, Murakami A, Kanai A, McLaren MJ, Inana G:Truncation and mutagenesis analysis of the human X-arrestin gene promoter. Gene 339:139-147.2004.
40. Funayama T, Ishikawa K, Ohtake Y, Tanino T, Kurosaka D, Kimura I, Suzuki K, IH, Nakamoto K, Yasuda N, Fujimaki T, Murakami A, Asaoka R, Hotta Y, Tanihara H, Kanamoto T, Mishima H, Fukuchi T, Abe H, Iwata T, Shimada N, Kudoh J, Shimizu N, Mashima Y: Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma. Invest Ophthalmol Vis Sci 45:4359-67, 2004.
41. Ishikawa K, Funayama T, Ohtake Y, Kimura I, Ideta H, Nakamoto K, Yasuda N, Fukuchi T, Fujimaki T, Murakami A, Asaoka R, Hotta Y, Kanamoto T, Tanihara H, Miyaki K, Mashima Y: Association between glaucoma and gene polymorphism of endothelin type A receptor. Mol Vis.11:431-7,2005.
42. Yokoyama T, Watanabe Y, Okisaka S, Murakami A: Macular hole secondary to epiretinal membrane in a juvenile patient. Am J Ophthalmol.139:357-359. 2005
43. Chen L, Kato T, Toshida H, Nakamura S, Murakami A: Immunohistochemical characterization of epithelial cells implanted in the flap-stroma interface of the cornea. Jpn J Ophthalmol 49:79-83, 2005.
44. Tian X, Fujiki K, Wang W, Murakami A, Xie P, Kanai A: Novel mutation (V505D) of the TGFBI gene found in a Chinese family with lattice corneal dystrophy, type I. Jpn J Ophthalmol 49:84-88, 2005.
45. Jin ZB, Liu XQ, Uchida A, Vervoort R, Morishita K, Hayakawa M, Murakami A, Matsumoto N, Niikawa N, Naoi N: Novel deletion spanning RCC1-like domain of RPGR in Japanese X-linked retinitis pigmentosa family. Mol Vis.11:535-41,2005
46. Ebihara N, Takai S, Miyazaki M, Murakami A: Mast cell chymase induces conjunctival epithelial cell apoptosis by a mechanism involving degradation of fibronectin. Curr Eye Res 30:429-35, 2005.
47. Ebihara N, Funaki T, Murakami A, Takai S, Miyazaki M: Mast cell chymase decreases the barrier function and inhibits the migration of corneal epithelial cells. Curr Eye Res 30:1061-1069, 2005.
48. Sato T, Uchida R, Tanigawa H, Uno K, Murakami A: Application of polymer gels containing side-chain phosphate groups to drug-delivery contact lenses. J. Appl Polym Sci: 98,731-735, 2005.
49. Lu W, Ebihara N, Miyazaki K, Murakami A: Reduced expression of laminin-5 in corneal epithelial cells under high glucose condition. Cornea 25:61-67, 2006.
50. Inagaki Y, Mashima Y, Funayama T, Ohtake Y, Fuse N, Yasuda N, Fukuchi T, Murakami A, Hotta Y: Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 13:1-7, 2006.
51. Yokoyama T, Fujiki K, Murakami A, Hotta Y: Long-term Follow-up of Two Sisters with Leber's Hereditary Optic Neuropathy. Jpn J Ophthalmol 50:78-80,2006.
52. Kanemoto M, Sato T, Aoyama A, Matsunaga T, Uno K, Toshida H, Murakami A: The interaction and compatibility between a soft contact lens and an ophthalmic drug. Eye Contact Lens 32 :192-6, 2006.
53. Inagaki Y, Mashima Y, Fuse N, Funayama T, Ohtake Y, Yasuda N, Murakami A, Hotta Y, Fukuchi T, Tsubota K: Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma Mol Vis.12:673-80, 2006.
54. Ebihara N, Nishikawa M, Murakami A: Disodium cromoglycate inhibits capsaicin-induced eosinophil infiltration of conjunctiva independent of mast cells. Jpn J Ophthalmol 50:205-10, 2006.
55. Jin ZB, Liu XQ, Hayakawa M, Murakami A, Naoi N: Mutational analysis of RPGR and RP2 genes in Japanese patients with retinitis pigmentosa: identification of four mutations Mol.Vis.12:1167-74,2006.
56. Funayama T, Mashima Y, Ohtake Y, Ishikawa K, Fuse N, Yasuda N, Fukuchi T, Murakami A, Hotta Y, Shimada N: SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma. Invest Ophthalmol Vis Sci.47:5368-75, 2006.
57. Takizawa Y, Hayashi S, Fujimaki T, Mizota A, Yokoyama T, Tanaka M, Murakami A: Central retinal vein occlusion caused by human herpesvirus 6. J Pediatr Ophthalmol Strabismus.43:176-8, 2006.
58. Ebihara N, Chen L, Tokura T, Ushio H, Iwatsu M, Murakami A: Distinct Functions between Toll-Like Receptors 3 and 9 in Retinal Pigment. Epithelial Cells. Ophthalmic Res.39:155-163, 2007.
59. Kubo SI, Iwatake A, Ebihara N, Murakami A, Hattori N: Visual impairment in Parkinson's disease treated with amantadine: Case report and review of the literature. Parkinsonism Relat Disord 14: 166-9, 2008.
60. Toshida H, Kogure N, Inoue N, Murakami. A: Trends in microbial keratitis in Japan. Eye Contact Lens 33:70-3, 2007.
61. Inoue N, Toshida H, Mamada N, Kogure N, Murakami A: Contact lens-induced infectious keratitis in Japan. Eye Contact Lens 33: 65-9, 2007.
62. Hiratsuka Y, Sasaki S, Nakatani S, Murakami A: Traumatic wound dehiscence after penetrating keratoplasty. Jpn J Ophthalmol51:146-7, 2007.
63. Ebihara N, Yamagami S, Yokoo S, Amano S, Murakami A: Involvement of C-C chemokine ligand 2-CCR2 interaction in monocyte-lineage cell recruitment of normal human corneal stroma. J Immunol 178:3288-92, 2007.
64. Ebihara N, Yamagami S, Chen L, Tokura T, Iwatsu M, Ushio H, Murakami A: Expression and function of toll-like receptor-3 and -9 in human corneal myofibroblasts. Invest Ophthalmol Vis Sci 48:3069-76. 2007.
65. Tian X, Fujiki K, Zhang Y, Murakami A, Li Q, Kanai A, Wang W, Hao Y, Ma Z: A novel variant lattice corneal dystrophy caused by association of mutation(V625D) in TGFBI gene. Am J Ophthalmol. 144:473-5,2007.
66. Kobayashi A, Fujiki K, Fujimaki T, Murakami A, Sugiyama K: In vivo laser confocal microscopic findings of corneal stromal dystrophies. Arch Ophthalmol. 125:1168-73, 2007.
67. Toshida H, Uesugi Y, Ebihara N, Murakami A: In Vivo Observations of a Case of Chlorpromazine Deposits in the Cornea Using an HRT II Rostock Corneal Module. Cornea. 26:1141-3,2007.
68. Toshida H, Nguyen DH, Beuerman RW, Murakami A: Evaluation of novel dry eye model: preganglionic parasympathetic denervation in rabbit. Invest Ophthalmol Vis Sci. 48:4468-75, 2007.
69. Kanemoto M, Toshida H, Takahiro I, Murakami A: Prosthetic soft contact lenses in Japan. Eye Contact Lens 33:300-3, 2007.
70. Nakatani S, Ebihara N, Murakami A: Stem cell factor in the tear fluid of vernal keratoconjunctivitis patients. Jpn J Ophthalmol.51:474-6, 2007.
71. Chen L, Ebihara N, Fujiki K, Murakami A: Expression and distribution of junctional adhesion molecule-1 in the human cornea. Jpn J Ophthalmol. 51:405-11, 2007.
72. Toshida H, Odaka A, Koike D, Murakami A: Effect of Retinol Palmitate Eye Drops on Experimental Keratoconjunctival Epithelial Damage Induced by n-Heptanol in Rabbit. Curr Eye Res. 33:13-8, 2008.
73. Funaki T, Ebihara N, Murakami A, Nakao A: Ex vivo transfer of Smad7 decreases damage to the corneal endothelium after penetrating keratoplasty. Jpn J Ophthalmol 52:204-10, 2008.
74. Seto T, Fujiki K, Kishishita H, Fujimaki T, Murakami A, Kanai A: A novel mutation in the cornea-specific keratin 12 gene in Meesmann corneal dystrophy. Jpn J Ophthalmol 52: 224-6, 2008.
75. Ebihara N, Funaki T, Matsuda H, Okumura K, Murakami A, Ra C: Corneal abnormalities in the NC/Nga mouse: an atopic dermatitis model Cornea.;27:923-9,2008.
76. ino Y, Fujimaki T, Fujiki K, Murakami A: A novel mutation (967-970+2)delAAAGGT in the choroideremia gene found in a Japanese family and related clinical findings. Jpn J Ophthalmol. 52:289-97, 2008.
77. Toshida H, Takahashi K, Sado K, Kanai A, Murakami A: Bifocal contact lenses: History, types, characteristics, and actual state and problems. Clin Ophthalmol 2:869-77,2008.
78. Toshida H, Nakayasu K, Murakami A: In vivo observation of rigid gas-permeable contact lens fragments embedded in cornea. Eye Contact Lens 35:105-7, 2009.
79. Toshida H, Nguyen D, Beuerman RW, Murakami A: Neurological evaluation of acute lacrimomimetic effect of Cyclosporine in an experimental rabbit dry eye model. Invest Ophthalmol Vis Sci 50: 2736-41, 2009.
80. Seto T, Takai T, Ebihara N, Matsuoka H, Wang XL, Ishii A, Ogawa H, Murakami A, Okumura K: LPI prevents cytokine release in mite protease-exposed conjunctival epithelial cells. Biochem Biophys Res Commun 379: 681-5, 2009.
81. Matsuda A, Okayama Y, Terai N, Yokoi N, Ebihara N, Tanioka H, Kawasaki S, Inatomi T, Katoh N, Ueda E, Hamuro J, Murakami A, Kinoshita S: The Role of Interleukin-33 in Chronic Allergic Conjunctivitis. Invest Ophthalmol Vis Sci 50:4646-52, 2009.
82. Toshida H, Murakami A: An atypical case of microcysts associated with silicone hydrogel contact lens: findings on in vivo confocal laser microscopy. Eye Contact Lens 35:156-8, 2009.
83. Kobayashi A, Fujiki K, Murakami A, Sugiyama K: In vivo laser confocal microscopy findings and mutational analysis for Schnyder's crystalline corneal dystrophy. Ophthalmology 116:1029-37,2009.
84. Ebihara N, Nakayama M, Tokura T, Ushio H, Murakami A.Expression and function of fibroblast growth factor-inducible 14 in human corneal myofibroblasts. Exp Eye Res 89:256-62,2009.
85. Ebihara N, Nakayama M, Tokura T, Iwatsu M, Ushio H, Murakami A. Proinflammatory effect of TWEAK/Fn14 interaction in human retinal pigment epithelial cells Curr Eye Res 34:836-4, 2009.
86. Sakuma K, Toshida H, Honda R, Tanaka K, Fukazawa A, Takahashi K, Suto C, Ebihara N, Murakami A:Effects of Topical Application of Ibudilast for Seasonal Allergic Conjunctivitis in Patients Wearing Soft Contact Lenses. Eye Contact Lens 35:251-4, 2009.
87. Himi M, Fujimaki T, Yokoyama T, Fujiki K, Takizawa T, Murakami A: A case of oculodentodigital dysplasia syndrome with novel GJA1 gene mutation. Jpn J Ophthalmol 53:541-5, 2009.
88. Ono K VisonnavongV, Konyama K, Hiratsuka Y, Murakami A: Geographical Distribution of Eye Health Professionals and Cataract Surgery in Lao PDR Ophthalmic Epidemiol 16: 354-61, 2009.
89. Watanabe Y, Hamanaka T, Takemura T, Murakami A. Involvement of platelet coagulation and inflammation in the endothelium of the Schlemm canal. Invest Ophthalmol Vis Sci 51: 277-283, 2010.
90. Matsuda A, Ebihara N, Yokoi N, Kawasaki S, Tanioka H, Inatomi T, de Waal Malefyt R, Hamuro J, Kinoshita S, Murakami A. Functional Roles of Thymic Stromal Lymphopoietin for Chronic Allergic Keratoconjunctivitis.Invest Ophthalmol Vis Sci 51:151-155, 2010.
91. Matsuda A, Ebihara N, Yokoi N, Okayama Y, Watanabe Y, Kawasaki S, Tanioka H, Walls AF, Hamuro J, Kinoshita S, Murakami A. Basophils in the giant papillae of chronic allergic keratoconjunctivitis. Br J Ophthalmol 94: 513-8,2010.
92. Ono K, Hiratsuka Y, Murakami A: Geographical distribution of ophthalmologists before and after the new postgraduate training program in Japan, Ophthalmic Epidemiol 17:125-30,2010.
93. Fukuoka H, Kawasaki S, Yamasaki K, Matsuda A, Fukumoto A, Murakami A, Kinoshita S.: Lattice Corneal Dystrophy Type IV (p.Leu527Arg) was Caused by a Founder Mutation of the TGFBI Gene in a Single Japanese Ancestor. Invest Ophthalmol Vis Sci.51:4523-30,2010.
94. Liu Z, Tian X, Iida, N,Fujiki Xie P Wang,W Ma Z, Kanai A, Murakami A.Mutation Analysis of CHST6 gene in Chinese Patients with Macular Corneal Dystrophy. Cornea 29:883-8,2010.
95. Ono K, Hiratsuka Y, Murakami A: Global Inequality in Eye Health. Am J Public Health 100:1784-8,2010.
96. Matsuda A, Murakami A:Lymphoid neogenesis in the giant papillae of patients with chronic allergic conjunctivitis" Journal of Allergy and Clinical Immunol.126:1310-2, 2010.
97. Ohtomo K, Ebihara N, Matsuda A, Tokura T, Funaki T, Murakami A: Role of TGF-β in tissue eosinophilia associated with vernal keratoconjunctivitis. Exp Eye Res.91:748-54, 2010.
98. Umeda Y, Nakamura S, Fujiki K, Toshida H, Saito A, Murakami A: Distribution of goblet cells and MUC5AC mRNA in the canine nictitating membrane. Exp Eye Res. Exp Eye Res 91:721-6, 2010.
99. Kobayakawa S, Hiratsuka Y, Watabe Y, Murakami A, Tochikubo T: Comparison of the influence of intracameral gentamicin, gatifloxacin, and moxifloxacin on the corneal endothelium in a rabbit model. Jpn J Ophthalmol 54:481-5, 2010.
100. Tano T, Hiratsuka Y, Ono K, Murakami A: Influence of cataract surgery and blood pressure changes caused by sodium restriction on retinal vascular diameter.Clinical Ophthalmology 4:1299–1309,2010
101. Marumoto T, Hiratsuka Y, Murakami A: The significance of the determination of lymphocytes with clinical manifestation of ophthalmic zoster sine herpete. Clin Ophthalmol.4:817-22, 2010.
102. Takihara Y, Inatani M, Seto T, Iwao K, Iwao M, Inoue T, Kasaoka N, Murakami A, Futa R, Tanihara H: Trabeculectomy with mitomycin C for open-angle glaucoma in phakic eyes vs pseudophakic eyes after phacoemulsification. Arch Ophthalmol 129:152-7, 2011.
103. Yamaguchi M, Ebihara N, Shima N, Kimoto M, Funaki T, Yokoo S, Murakami A, Yamagami S: Adhesion, migration, and proliferation of cultured human corneal endothelial cells by laminin-5. Invest Ophthalmol Vis Sci.52:679-84. 2011.
104. Kartasasmita A, Fujiki K, Iskandar E, Sovani I, Fujimaki T, Murakami A: A novel nonsense mutation in rhodopsin gene in two Indonesian families with autosomal recessive retinitis pigmentosa. Ophthalmic Genet 2:57-63, 2011.
105. Shinoda H, Koto T, Fujiki K, Murakami A, Tsubota K, Ozawa Y: Clinical findings in a choroideremia patient who underwent vitrectomy for retinal detachment associated with macular hole. Jpn J Ophthalmol 55:169-71, 2011.
106. Ishida Y, Yanai R, Sagara T, Nishida T, Toshida H, Murakami A: Decrease in intraocular pressure following orthokeratology measured with a noncontact tonometer. Jpn J Ophthalmol 55:190-5, 2011.
107. Ebihara N, Ohtomo K, Tokura T, Ushio H, Murakami A. Effect of Tacrolimus on Chemokine Production by Corneal Myofibroblasts via Toll-Like Receptors, Compared with Cyclosporine and Dexamethasone. Cornea. 30:702-8, 2011.
108. Hiratsuka Y, Yamada M, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T: Eye Care Comparative Effectiveness Research Team (ECCERT).Cost-effectiveness of cataract surgery in Japan. Jpn J Ophthalmol.55:333-42, 2011.
109. Ebihara N, Matsuda A, Nakamura S, Matsuda H, Murakami A: Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing. Invest Ophthalmol Vis Sci 52:8549-57, 2011.
110. Honda R, Toshida H, Suto C, Fujimaki T, Kimura T, Ohta T, Murakami A: Effect of long-term treatment with eyedrops for glaucoma on conjunctival bacterial flora. Infect Drug Resist 4:191-6, 2011.
111. Hamahata T, Fujimaki T, Fujiki K, Miyazaki A, Mizota A, Murakami A: OPA1 mutations in Japanese patients suspected to have autosomal dominant optic atrophy. Jpn J Ophthalmol 56:91-97, 2012
112. Sakanishi Y, Awano M, Mizota A, Tanaka M, Murakami A, Ohnuma K: Age-Related Changes in Spectral Transmittance of the Human Crystalline Lens in situ. Ophthalmologica 228:174-180, 2012.
113. Tamura K, Yokoyama T, Ebihara N, Murakami A:Histopathologic analysis of the internal limiting membrane surgically peeled from eyes with diffuse diabetic macular edema. Jpn J Ophthalmol 56:280-287, 2012.
114. Hori K, Matsuda A, Ebihara N, Imai K, Mori K, Funaki T, Watanabe Y, Nakatani S, Okada K, Matsuo O, Murakami A: Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts. Invest Ophthalmol Vis Sci. 53:1846-1851, 2012.
115. Uchida Y, Kudoh D, Murakami A, Honda M, Kitazawa S: Origins of superior dynamic visual acuity in baseball players: superior eye movements or superior image processing. PLoS One 7: e31530, 2012.
116. Toshida H, Kadota Y, Suto C, Ohta T, Murakami A: Multipurpose soft contact lens care in Japan. Clin Ophthalmol. 6:139-44, 2012.
117. Inomata T, Ebihara N, Funaki T, Matsuda A, Watanabe Y, Ning L, Xu Z, Murakami A, Arikawa-Hirasawa E: Perlecan-deficient mutation impairs corneal epithelial structure. Invest Ophthalmol Vis Sci 53:1277-84,2012.
118. Iwamoto S, Ebihara N, Hori K, Funaki T, Asada Y, Yokoi N, Inatomi T, Kawasaki S, Murakami A, Matsuda A: Filaggrin mutations are not associated with chronic allergic keratoconjunctivitis. Br J Ophthalmol. 96:1272-3, 2012.
119. Toshida H, Ohta T, Murakami A, Kobayashi A, Sugiyama K. Descemet stripping automated endothelial keratoplasty for microcornea. Jpn J Ophthalmol 56:436-40, 2012.
120. Toshida H, Tabuchi N, Koike D, Koide M, Sugiyama K, Nakayasu K, Kanai A, Murakami A: The effects of vitamin A compounds on hyaluronic acid released from cultured rabbit corneal epithelial cells and keratocytes. J Nutr Sci Vitaminol (Tokyo).;58:223-9, 2012.
121. Odaka A, Toshida H, Ohta T, Tabuchi N, Koike D, Suto C, Murakami A. Efficacy of retinol palmitate eye drops for dry eye in rabbits with lacrimal gland resection. Clin Ophthalmol.6:1585-93, 2012.
122. Amano K, Ishiguchi M, Aikawa T, Kimata M, Kishi N, Fujimaki T, Murakami A, Kogo M: Cleft lip in oculodentodigital dysplasia suggests novel roles for connexin43. J Dent Res.91(7 Suppl):38S-44S, 2012.
123. Yamamoto S, Sugawara T, Murakami A, Nakazawa M, Nao-I N, Machida S, Wada Y, Mashima Y, Miyake Y: Erratum to: Topical Isopropyl Unoprostone for Retinitis Pigmentosa: Microperimetric Results of the Phase 2 Clinical Study. Ophthalmol Ther 2:53, 2013.
124. Sasaki H, Takano T, Murakami A. Direct endoscopic probing for congenital lacrimal duct obstruction. Clin Experiment Ophthalmol 41:729-34, 2013.
125. Toshida H, Ohta T, Suto C, Murakami A. Effect of subconjunctival lacrimal gland transplantation in a rabbit dry eye model. Cornea 32 Suppl 1:S46-51, 2013.
126. Eye Care Comparative Effectiveness Research Team (ECCERT), Hiratsuka Y, Yamada M, Akune Y, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T: Cost-utility analysis of cataract surgery in Japan: a probabilistic Markov modeling study. Jpn J Ophthalmol 57:391-401, 2013.
127. Matsui A, Toshida H, Honda R, Seto T, Ohta T, Murakami A:Preoperative and postoperative optical coherence tomography findings in patients with rhegmatogenous retinal detachment involving the macular region. ISRN Ophthalmol 2013 Sep:426867,2013. doi: 10.1155/2013/426867. PMID: 24563793; PMCID: PMC3914191.
128. Kitazawa K, Kawasaki S, Shinomiya K, Aoi K, Matsuda A, Funaki T, Yamasaki K, Nakatsukasa M, Ebihara N, Murakami A, Hamuro J, Kinoshita S: Establishment of a human corneal epithelial cell line lacking the functional TACSTD2 gene as an in vitro model for gelatinous drop-like dystrophy. Invest Ophthalmol Vis Sci 54:5701-11, 2013.
129. Nakatani S, Murakami A: Descemet stripping automated endothelial keratoplasty for bullous keratopathy after anterior-posterior radial keratotomy. Cornea. 32:1179-82, 2013.
130. Toshida H, Honda R, Matsui A, Matsuzaki Y, Shimizu Y, Seto T, Ohta T, Murakami A: Double-glide method using Cathereep® protective sheet as a substitute in Descemet’s stripping automated endothelial keratoplasty. ISRN Transplantation. 2013 Article ID 713153, 2013.
131. Usui A, Mochizuki Y, Iida A, Miyauchi E, Satoh S, Sock E, Nakauchi H, Aburatani H, Murakami A, Wegner M, Watanabe S: The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells. Development 140:740-50, 2013.
132. Usui A, Iwagawa T, Mochizuki Y, Iida A, Wegner M, Murakami A, Watanabe S: Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinaldevelopment. FEBS Lett587:358-63, 2013.
133. Matsuzaki Y, Toshida H, Ohta T, Murakami A: A case of atypical mucin balls wearing extended wear of silicone hydrogel lens for therapeutic use. Case Rep Ophthalmol Med. 2013:167854, 2013.
134. Sasaki H, Takano T, Murakami A: Direct endoscopic probing for congenital lacrimal duct obstruction. Clin Experiment Ophthalmol. 7: 695-702, 2013.
135. Shimizu Y, Toshida H, Honda R, Matsui A, Ohta T, Asada Y, Murakami A: Prevalence of drug resistance and culture-positive rate among microorganisms isolated from patients with ocular infections over a 4-year period. Clin Ophthalmol.7:695-702, 2013.
136. Tano T, Ono K, Hiratsuka Y, Otani K, Sekiguchi M, Konno S, Kikuchi S, Onishi Y, Takegami M, Yamada M, Fukuhara S, Murakami A. Prevalence of pterygium in a population in Northern Japan: the Locomotive Syndrome and Health Outcome in Aizu Cohort Study. Acta Ophthalmol 91:e232-6, 2013.
137. Iwamoto S, Asada Y, Ebihara N, Hori K, Okayama Y, Kashiwakura J, Watanabe Y, Kawasaki S, Yokoi N, Inatomi T, Shinomiya K, Murakami A, Matsuda A: Interaction between conjunctival epithelial cells and mast cells induces CCL2 expression and piecemeal degranulation in mast cells. Invest Ophthalmol Vis Sci 54:2465-73, 2013.
138. Kasuga T, Chen YC, Bloomer MM, Hirabayashi KE, Hiratsuka Y, Murakami A, Lin SC: Trabecular meshwork length in men and women by histological assessment. Curr Eye Res 38:75-9, 2013.
139. Kobayashi H, Okamoto H, Murakami A, Iwata T: Plasma proteome analysis on cynomolgus monkey (macaca fascicularis) pedigrees with early onset drusen formation. Exp Anim. 63:305-10, 2014.
140. Hiratsuka Y, Yamada M, Akune Y, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T. Assessment of vision-related quality of life among patients with cataracts and the outcomes of cataract surgery using a newly developed visual function questionnaire: the VFQ-J11. Jpn J Ophthalmol 58:415-22, 2014.
141. Arai E, Fujimaki T, Yanagawa A, Fujiki K, Yokoyama T, Okumura A, Shimizu T, Murakami A: Familial cases of Norrie disease detected by copy number analysis. Jpn J Ophthalmol. 58:448-54, 2014.
142. Nakatani S, Murakami A: Three-year outcome of descemet stripping automated endothelial keratoplasty for bullous keratopathy after argon laser iridotomy. Cornea 33:780-4, 2014.
143. Mochizuki Y, Iida A, Lyons E, Kageyama R, Nakauchi H, Murakami A, Watanabe S. Use of cell type-specific transcriptome to identify genes specifically involved in Müller glia differentiation during retinal development. Dev Neurobiol 74:426-37, 2014.
144. Ohta T, Toshida H, Murakami A. Simplified and safe method of sutureless intrascleral posterior chamber intraocular lens fixation: Y-fixation technique. J Cataract Refract Surg. 40:2-7, 2014.
145. Asada Y, Ebihara N, Funaki T, Yokoi N, Murakami A, Matsuda A: Vernal keratoconjunctivitis with giant papillae on the inferior tarsal conjunctiva. Cornea. 33:32-4, 2014.
146. Inagaki K, Ohkoshi K, Ohde S, Deshpande GA, Ebihara N, Murakami A: Subthreshold Micropulse Photocoagulation for Persistent Macular Edema Secondary to Branch Retinal Vein Occlusion including Best-Corrected Visual Acuity Greater Than 20/40. J Ophthalmol 2014:251-7, 2014.
147. Iida A, Iwagawa T, Kuribayashi H, Satoh S, Mochizuki Y, Baba Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S: Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells. Proc Natl Acad Sci U S A 111:3751-6, 2014.
148. Suzuki T, Fujimaki T, Yanagawa A, Arai E, Fujiki K, Wada Y, Murakami A: A novel exon 17 deletion mutation of RPGRIP1 gene in two siblings with Leber congenital amaurosis. Jpn J Ophthalmol. 58:528-35, 2014.
149. Arai R, Kimura I, Imamura Y, Shinoda K, Matsumoto CS, Seki K, Ishida M, Murakami A, Mizota A: Photoreceptor inner and outer segment layer thickness in multiple evanescent white dot syndrome. Graefes Arch Clin Exp Ophthalmol. 252:1645-51, 2014.
150. Iida A, Iwagawa T, Baba Y, Satoh S, Mochizuki1 Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S: Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation. Dev Neurobiol. 75:947-960, 2015.
151. Inagaki K, Shuo T, Katakura K, Ebihara N, Murakami A, Ohkoshi K: Sublethal Photothermal Stimulation with a Micropulse Laser Induces Heat Shock Protein Expression in ARPE-19 Cells. J Ophthalmol. 2015:729792,2015.
152. Takakuwa K, Hamanaka T, Mori K, Chin S, Shinmei Y, Funaki T, Ebihara N, Ono K, Murakami A, Matsuda A: Atopic Glaucoma: Clinical and Pathophysiological Analysis. J Glaucoma 24:662-8, 2015.
153. Coppieters F, Todeschini AL, Fujimaki T, Baert A, De Bruyne M, Van Cauwenbergh C, Verdin H, Bauwens M, Ongenaert M, Kondo M, Meire F, Murakami A, Veitia RA, Leroy BP, De Baere E: Hidden Genetic Variation in LCA9-Associated Congenital Blindness Explained by 5'UTR Mutations and Copy-Number Variations of NMNAT1. Hum Mutat 36:1188-96, 2015.
154. Asada Y, Nakae S, Ishida W, Hori K, Sugita J, Sudo K, Fukuda K, Fukushima A, Suto H, Murakami A, Saito H, Ebihara N, Matsuda A: Roles of Epithelial Cell-Derived Type 2-Initiating Cytokines in Experimental Allergic Conjunctivitis.Invest Ophthalmol Vis Sci. 56:5194-202, 2015.
155. Kakigi C, Kasuga T, Wang SY, Singh K, Hiratsuka Y, Murakami A, Lin SC: Hypothyroidism and Glaucoma in The United States. PLoS One 10:e0133688, 2015.
156. Matsuda A, Asada Y, Takakuwa K, Sugita J, Murakami A, Ebihara N: DNA Methylation Analysis of Human Trabecular Meshwork Cells During Dexamethasone Stimulation. Invest Ophthalmol Vis Sci. 56:3801-9, 2015.
157. Arai E, Baba Y, Iwagawa T, Kuribayashi H, Mochizuki Y, Murakami A, Watanabe S: Ablation of Kcnj10 expression in retinal explants revealed pivotal roles for Kcnj10 in the proliferation and development of Müller glia. Mol Vis. 21:148-59, 2015.
158. Yamaguchi M, Shima N, Kimoto M, Ebihara N, Murakami A, Yamagami S: Markers for Distinguishing Cultured Human Corneal Endothelial Cells from Corneal Stromal Myofibroblasts. Curr Eye Res 40:1211-7, 2015.
159. Inagaki K, Ohkoshi K, Ohde S, Deshpande GA, Ebihara N, Murakami A: Comparative efficacy of pure yellow (577-nm) and 810-nm subthreshold micropulse laser photocoagulation combined with yellow (561-577-nm) direct photocoagulation for diabetic macular edema. Jpn J Ophthalmol 59: 21-28, 2015.
160. Nakano T, Kawashima M, Hiratsuka Y, Tamura H, Ono K, Murakami A, Tsubota K, Yamada M: Assessment of quality of life in patients with visual impairments using a new visual function questionnaire: the VFQ-J11. Clin Ophthalmol 10: 1939-44, 2016.
161. Tamaki K, Usui-Ouchi A, Murakami A, Ebihara N. Fibrocytes and Fibrovascular Membrane Formation in Proliferative Diabetic Retinopathy.Invest Ophthalmol Vis Sci. 57: 4999-5005, 2016.
162. Toride A, Toshida H, Matsui A, Matsuzaki Y, Honda R, Ohta T, Murakami A. Visual outcome after emergency surgery for open globe eye injury in Japan. Clin Ophthalmol 10: 1731-1736, 2016.
163. Shimazaki J, Maeda N, Hieda O, Ohashi Y, Murakami A, Nishida K, Tsubota K; Japan Pellucid Marginal Corneal Degeneration Study Group.National survey of pellucid marginal corneal degeneration in Japan. Jpn J Ophthalmol. 60:341-8, 2016.
164. Ueno K, Iwagawa T, Kuribayashi H, Baba Y, Nakauchi H, Murakami A, Nagasaki M, Suzuki Y, Watanabe S: Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation. Sci Rep.6:29264,2016.
165. Nakatani S, Murakami A: Descemet stripping automated endothelial keratoplasty using corneas from elderly donors. Graefes Arch Clin Exp Ophthalmol. 254:1135-40, 2016.
166. Yamaguchi M, Shima N, Kimoto M, Ebihara N, Murakami A, Yamagami S: Optimization of Cultured Human Corneal Endothelial Cell Sheet Transplantation and Post-Operative Sheet Evaluation in a Rabbit Model. Curr Eye Res. 41: 1178-1184, 2016.
167. Tano T, Ono K, Hiratsuka Y, Otani K, Sekiguchi M, Konno S, Kikuchi S, Onishi Y, Takegami M, Yamada M, Fukuhara S, Murakami A:Retinal vessel diameters in a Japanese population: the Locomotive Syndrome and Health Outcome in Aizu Cohort Study. Acta Ophthalmol 94: e432-441, 2016.
168. Kawashima M, Hiratsuka Y, Nakano T, Tamura H, Ono K, Murakami A, Inoue S, Tsubota K, Yamada M: The association between legal Japanese visual impairment grades and vision-related quality of life. Jpn J Ophthalmol. 60:219-25, 2016.
169. Toshida H, Funaki T, Ono K, Tabuchi N, Watanabe S, Seki T, Otake H, Kato T, Ebihara N, Murakami A: Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial. Drug Des Devel Ther11:1871-79, 2017.
170. Arai R, Usui-Ouchi A, Ito Y, Mashimo K, Murakami A, Ebihara N: Effects of Secreted Mast Cell Mediators on Retinal Pigment Epithelial Cells: Focus on Mast Cell Tryptase. Mediators Inflamm.2017:3124753,2017.
171. Iwamoto S, Koga T, Ohba M, Okuno T, Koike M, Murakami A, Matsuda A, Yokomizo T: Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B(4) receptor 2. Sci Rep 16:13267, 2017.
172. Inomata T, Ono K, Matsuba T, Shiang T, Di Zazzo A, Nakatani S, Yamaguchi M, Ebihara N, Murakami A: Pre-banking microbial contamination of donor conjunctiva and storage medium for penetrating keratoplasty. Jpn J Ophthalmol.61:369-77, 2017.
173. Iwatake A, Murakami A, Ebihara N: The expression of matrix metalloproteinases and their inhibitors in corneal fibroblasts by alarmins from necrotic corneal epithelial cells. Jpn J Ophthalmol. 62:92-100, 2017.
174. Kasuga T, Aruga F, Ono K, Hiratsuka Y, Murakami A: Visual impairment as an independent risk factor for falls in hospitalized patients. Can J Ophthalmol 52:559-63, 2017.
175. Inomata T, Shiang T, Iwagami M, Sakemi F, Fujimoto K, Okumura Y, Ohno M, Murakami A: Changes in Distribution of Dry Eye Disease by the New 2016 Diagnostic Criteria from the Asia Dry Eye Society. Sci Rep. 8:1918,2018 Erratum in: Sci Rep.8:10368, 2018.
176. Hamada M, Ohkoshi K, Inagaki K, Ebihara N, Murakami A: Visualization of microaneurysms using optical coherence tomography angiography: comparison of OCTA en face, OCT B-scan, OCT en face, FA, and IA images. Jpn J Ophthalmol. 62:168-75, 2018.
177. Takei M, Obana A, Inomata T, Tanaka T, Shiang T, Bae Y, Takemura T, Murakami A: Fundus changes in type III membranoproliferative glomerulonephritis: a case report. BMC Ophthalmol. 18:72, 2018.
178. Hamada M, Ohkoshi K, Inagaki K, Ebihara N, Murakami A. Subthreshold Photocoagulation Using Endpoint Management in the PASCAL® System for Diffuse Diabetic Macular Edema. J Ophthalmol 2018:7465794, 2018.
179. Inoue S, Kawashima M, Hiratsuka Y, Nakano T, Tamura H, Ono K, Murakami A, Tsubota K, Yamada M: Assessment of physical inactivity and locomotor dysfunction in adults with visual impairment. Sci Rep. 8:12032, 2018.
180. Kawamura Y, Suga A, Fujimaki T, Yoshitake K, Tsunoda K, Murakami A, Iwata T: LRRTM4-C538Y novel gene mutation is associated with hereditary macular degeneration with novel dysfunction of ON-type bipolar cells. J Hum Genet 63: 893-900, 2018.
181. Kuribayashi H, Baba Y, Iwagawa T, Arai E, Murakami A, Watanabe S: Roles of Nmnat1 in the survival of retinal progenitors through the regulation of proapoptotic gene expression via histone acetylation. Cell Death Dis 309:891, 2018.
182. Inomata T, Iwagami M, Hiratsuka Y, Fujimoto K, Okumura Y, Shiang T, Murakami A. Maximum blink interval is associated with tear film breakup time: A new simple, screening test for dry eye disease. Sci Rep 8:13443, 2108.
183. Nishino T, Kobayashi A, Mori N, Masaki T, Yokogawa H, Fujiki K, Yanagawa A, Murakami A, Sugiyama K: In vivo histology and p.L132V mutation in KRT12 gene in Japanese patients with Meesmann corneal dystrophy. Jpn J Ophthalmol 63:46-55, 2019.
184. Okumura Y, Inomata T, Iwagami M, Eguchi A, Mizuno J, Shiang T, Kawasaki S, Shimada A, Inada E, Amano A, Murakami A: Shortened cataract surgery by standardisation of the perioperative protocol according to the Joint Commission International accreditation: a retrospective observational study. BMJ Open. 9: e028656, 2019.
185. Nikopoulos K, Cisarova K, Quinodoz M, Koskiniemi-Kuendig H, Miyake N,Farinelli P, Rehman AU, Khan MI, Prunotto A, Akiyama M, Kamatani Y, Terao C, MiyaF, Ikeda Y, Ueno S, Fuse N, Murakami A, Wada Y, Terasaki H, Sonoda KH, Ishibashi T, Kubo M, Cremers FPM, Kutalik Z, Matsumoto N, Nishiguchi KM, Nakazawa T,Rivolta C. A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy. Nat Commun 10:2884, 2019.
186. Koyanagi Y, Akiyama M, Nishiguchi KM, Momozawa Y, Kamatani Y, Takata S, Inai C, Iwasaki Y, Kumano M, Murakami Y, Omodaka K, Abe T, Komori S, Gao D, Hirakata T, Kurata K, Hosono K, Ueno S, Hotta Y, Murakami A, Terasaki H, Wada Y, Nakazawa T, Ishibashi T, Ikeda Y, Kubo M, Sonoda KH: Genetic characteristics of retinitis pigmentosa in 1204 Japanese patients. J Med Genet 56:662-70, 2019.
187. Nishiguchi KM, Ikeda Y, Fujita K, Kunikata H, Akiho M, Hashimoto K, Hosono K, Kurata K, Koyanagi Y, Akiyama M, Suzuki T, Kawasaki R, Wada Y, Hotta Y, SonodaKH, Murakami A, Nakazawa M, Nakazawa T, Abe T: Phenotypic Features of Oguchi Disease and Retinitis Pigmentosa in Patients with S-Antigen Mutations: A Long-Term Follow-up Study. Ophthalmology 126:155-66, 2019.
188. Okumura Y, Inomata T, Miyamoto S, Nakatani S, Hiratsuka Y, Yamaguchi M, Iwamoto S, Murakami A. Donor characteristics and risk factors for methicillin-resistant Staphy lococcus aureus contamination in storage medium for corneal transplantation: A 10-year retrospective study. Transpl Infect Dis 126: e13123, 2019.
189. Hirakata T, Lee HC, Ohba M, Saeki K, Okuno T, Murakami A, Matsuda A, YokomizoT: Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating T(h)2 immune responses. FASEB J 33:3392-3403, 2019.
190. Honda R, Kasuga T, Murakami A, Matsuda A: Effects of the Numbers and the Shapes of Venting Slits on Intraocular Pressure after Baerveldt Glaucoma Drainage Implant. Curr Eye Res 44:921-4, 2019.
191. Miyagawa Y, Murakami A, Ebihara N: The proteolytic effect of mast cell tryptase to eotaxin-1/CCL11·eotaxin-2/CCL24 and eotaxin-3/CCL26 produced by conjunctival fibroblasts. Jpn J Ophthalmol 63:215-20, 2019.
192. Inomata T, Nakamura M, Iwagami M, Shiang T, Yoshimura Y, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Hori S, Hiratsuka Y, Uchino M, Tsubota K, Dana R, Murakami A: Risk Factors for Severe Dry Eye Disease: Crowdsourced Research Using DryEyeRhythm. Ophthalmology 126:766-8, 2019.
193. Sadamatsu Y, Hiratsuka Y, MichihataN, Jo T, Matsui H, Murakami A, Fushimi K, Yasunaga H: Activity of daily living improvement after cataract surgery for patients in nursing care facilities. Annals of Clinical Epidemiology 1:80-85, 2019.
194. Iwagawa T, Aihara Y, Umutoni D, Baba Y, Murakami A, Miyado K, Watanabe S: Cd9 Protects Photoreceptors from Injury and Potentiates Edn2 Expression. Invest Ophthalmol Vis Sci. 2020 Mar 9;61(3):7. doi: 10.1167/iovs.61.3.7. PubMed PMID:32150249.
195. Inomata T, Iwagami M, Nakamura M, Shiang T, Fujimoto K, Okumura Y, Iwata N,Fujio K, Hiratsuka Y, Hori S, Tsubota K, Dana R, Murakami A: Association between dry eye and depressive symptoms: Large-scale crowdsourced research using the DryEyeRhythm iPhone application. Ocul Surf 18:312-319, 2020.
196. Nishiguchi KM, Kunikata H, Fujita K, Hashimoto K, Koyanagi Y, Akiyama M, IkedaY, Momozawa Y, Sonoda KH, Murakami A, Wada Y, Nakazawa T: Association of CRX phenotypes and retinal phenotypes confounded by variable expressivity and electronegative electroretinogram. Clin Exp Ophthalmol 48:644-657, 2020.
197. Fujimoto K, Inomata T, Okumura Y, Iwata N, Fujio K, Eguchi A, Nagino K, Shokirova H, Karasawa M, Murakami A: Comparison of corneal thickness in patients with dry eye disease using the Pentacam rotating Scheimpflug camera and anterior segment optical coherence tomography. PLoS One 15: e0228567, 2020.
198. Yoshida Y, Hiratsuka Y, Kawachi I, Murakami A, Kondo K, Aida J: Association　between visual status and social participation in older Japanese: The JAGES　cross-sectional study. Soc Sci Med 253:112959, 2020.
199. Inomata T, Nakamura M, Iwagami M, Midorikawa-Inomata A, Okumura Y, Fujimoto K, Iwata N, Eguchi A, Shokirova H, Miura M, Fujio K, Nagino K, Nojiri S, Murakami A: Comparing the Japanese Version of the Ocular Surface Disease Index and Dry Eye-Related Quality-of-Life Score for Dry Eye Symptom Assessment. Diagnostics (Basel) 10: 203, 2020.
200. Koiwa C, Nakatani S, Inomata T, Yamaguchi M, Iwamoto S, Murakami A: Multiple　excimer laser phototherapeutic keratectomies for Avellino corneal dystrophy: a case report. Int J Ophthalmol 13: 841-844, 2020.
201. Inomata T, Nakamura M, Iwagami M, Midorikawa-Inomata A, Sung J, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Fujio K, Nagino K, Hori S, Tsubota K, Dana R, Murakami A: Stratification of Individual Symptoms of Contact Lens-Associated Dry Eye Using the iPhone App DryEyeRhythm: Crowdsourced Cross-Sectional Study. J Med Internet Res 22:e18996,2020. doi: 10.2196/18996.PMID: 32589162
202. Kabashima K, Murakami A, Ebihara N: Effects of Benzalkonium Chloride and Preservative-Free Composition on the Corneal Epithelium Cells. J Ocul Pharmacol Ther 10:10,2019.
203. Inomata T, Sung J, Nakamura M, Fujisawa K, Muto K, Ebihara N, Iwagami M, Nakamura M, Fujio K, Okumura Y, Okano M, Murakami A: New medical big data for P4 medicine on allergic conjunctivitis. Allergol Int 69:510-518.2020.
204. Inomata T, Kitazawa K, Kuno T, Sung J, Nakamura M, Iwagami M, Takagi H, Midorikawa-Inomata A, Zhu J, Fujimoto K, Okumura Y, Miura M, Fujio K, Hirosawa K, Akasaki Y, Kuwahara M, Dana R, Murakami A: Clinical and Prodromal Ocular Symptoms in Coronavirus Disease: A Systematic Review and Meta-Analysis. Invest Ophthalmol Vis Sci 61:29, 2020
205. Hirosawa K, Inomata T, Sung J, Nakamura M, Okumura Y, Midorikawa-Inomata A, Miura M, Fujio K, Akasaki Y, Fujimoto K, Zhu J, Eguchi A, Nagino K, Kuwahara M, Shokirova H, Yanagawa A, Murakami A. Diagnostic ability of maximum blink interval together with Japanese version of Ocular Surface Disease Index score for dry eye disease. Sci Rep 10:18106, 2020.
206. Hayashi T, Kameya S, Mizobuchi K, Kubota D, Kikuchi S, Yoshitake K, Mizota A, Murakami A, Iwata T, Nakano T: Genetic defects of CHM and visual acuity outcome in 24 choroideremia patients from 16 Japanese families. Sci Rep10:15883, 2020.
207. Inomata T, Sung J, Nakamura M, Iwagami M, Okumura Y, Iwata N, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Nagino K, Fujio K, Miura M, Shokirova H, Murakami A: Using Medical Big Data to Develop Personalized Medicine for Dry Eye Disease. Cornea 39 (Suppl 1):S39-S46, 2020
208. Inomata T, Fujimoto K, Okumura Y, Zhu J, Fujio K, Shokirova H, Miura M, Okano M, Funaki T, Sung J, Negishi N, Murakami A: Novel immunotherapeutic effects of topically administered ripasudil (K-115) on corneal allograft survival. Sci Rep 10:19817, 2020.
209. Hirakata T, Fujinami K, Saito W, Kanda A, Hirakata A, Ishida S, Murakami A, Tsunoda K, Miyake Y: Acute unilateral inner retinal dysfunction with photophobia: importance of electrodiagnosis. Jpn J Ophthalmol 65:42-53, 2020.
210. Eguchi A, Inomata T, Nakamura M, Nagino K, Iwagami M, Sung J, Midorikawa-Inomata A, Okumura Y, Fujio K, Fujimoto K, Miura M, Akasaki Y, Shokirova H, Hirosawa K, Kuwahara M, Zhu J, Dana R, Murakami A, Kobayashi H: Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application. Jpn J Ophthalmol 65: 42-53. 2021.
211. Mashimo K, Usui-Ouchi A, Ito Y, Wakasa-Arai R, Yokoi N, Kawasaki S, Murakami A, Matsuda A, Ebihara N: Role of oncostatin M in the pathogenesis of vernal keratoconjunctivitis: focus on tissue remodeling. Jpn J Ophthalmol 65:144-153, 2021.
212. Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Sato K, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda KH, Rivolta C, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T: A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa. Commun Biol 4:140,2021.
213. Kudo D, Hiratsuka Y, Nakamura M, Uchida Y, Ono S, Murakami A: Optimal methods for estimating sports vision in kendo athletes. Sci Rep 11:315, 2021.
214. Koyanagi Y, Akiyama M, Nishiguchi KM, Momozawa Y, Kamatani Y, Takata S, Inai C, Iwasaki Y, Kumano M, Murakami Y, Komori S, Gao D, Kurata K, Hosono K, Ueno S, Hotta Y, Murakami A, Terasaki H, Wada Y, Nakazawa T, Ishibashi T, Ikeda Y, Kubo M, Sonoda KH: Regional differences in genes and variants causing retinitis pigmentosa in Japan. Jpn J Ophthalmol 65:338-343, 2021.
215. Kimura M, Ando T, Kume Y, Fukase S, Matsuzawa M, Kashiwagi K, Izawa K, Kaitani A, Nakano N, Maeda K, Ogawa H, Okumura K, Nakao S, Murakami A, Ebihara N, Kitaura J. A nerve-goblet cell association promotes allergic conjunctivitis through rapid antigen passage. JCI Insight 8:e168596,2023.
216. Inomata T, Sung J, Nakamura M, Iwagami M, Akasaki Y, Fujio K, Nakamura M, Ebihara N, Ide T, Nagao M, Okumura Y, Nagino K, Fujimoto K, Eguchi A, Hirosawa K, Midorikawa Inomata A, Muto K, Fujisawa K, Kikuchi Y, Nojiri S, Murakami A: Using the AllerSearch Smartphone App to Assess the Association Between Dry Eye and Hay Fever: mHealth-Based Cross-Sectional Study. J Med Internet Res 25: e38481,2023.
217. Fujio K, Nagino K, Huang T, Sung J, Akasaki Y, Okumura Y, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Miura M, Hurramhon S, Yee A, Hirosawa K, Ohno M, Morooka Y, Murakami A, Kobayashi H, Inomata T: Clinical utility of maximum blink interval measured by smartphone application DryEyeRhythm to support dry eye disease diagnosis. Sci Rep 13:13583, 2023.
218. Nagino K, Okumura Y, Akasaki Y, Fujio K, Huang T, Sung J, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Hurramhon S, Yee A, Miura M, Ohno M, Hirosawa K, Morooka Y, Murakami A, Kobayashi H, Inomata T: Smartphone App-Based and Paper-Based Patient-Reported Outcomes Using a Disease-Specific Questionnaire for Dry Eye Disease: Randomized Crossover Equivalence Study. J Med Internet Res 25:e42638, 2023.
219. Nagino K, Inomata T, Nakamura M, Sung J, Midorikawa-Inomata A, Iwagami M, Fujio K, Akasaki Y, Okumura Y, Huang T, Fujimoto K, Eguchi A, Miura M, Hurramhon S, Zhu J, Ohno M, Hirosawa K, Morooka Y, Dana R, Murakami A, Kobayashi H. Symptom-based stratification algorithm for heterogeneous symptoms of dry eye disease: a feasibility study. Eye (Lond) 37: 3484-3491, 2023.
220. Watanabe K, Hiratsuka Y, Yamamoto S, Murakami A: Economic Impacts and Quality of Life for Caregivers of Patients with Retinitis Pigmentosa: A Cross-Sectional Japanese Study. Healthcare (Basel) 11: 988, 2023.
221. Watanabe K, Aouadj C, Hiratsuka Y, Yamamoto S, Murakami A. Quality of Life and Economic Impacts of Retinitis Pigmentosa on Japanese Patients: A Non-interventional Cross-sectional Study. Adv Ther 40: 2375-2393, 2023.
222. Matsuzawa M, Ando T, Fukase S, Kimura M, Kume Y, Ide T, Izawa K, Kaitani A, Hara M, Nakamura E, Kamei A, Matsuda A, Nakano N, Maeda K, Tada N, Ogawa H, Okumura K, Murakami A, Ebihara N, Kitaura J: The protective role of conjunctival goblet cell mucin sialylation. Nat Commun 14:1417,2023.
223. Inomata T, Sung J, Fujio K, Nakamura M, Akasaki Y, Nagino K, Okumura Y, Iwagami M, Fujimoto K, Ebihara N, Nakamura M, Midorikawa-Inomata A, Shokirova H, Huang T, Hirosawa K, Miura M, Ohno M, Morooka Y, Iwata N, Iwasaki Y, Murakami A: Individual multidisciplinary clinical phenotypes of nasal and ocular symptoms in hay fever: Crowdsourced cross-sectional study using AllerSearch. Allergol Int 72: 418-427, 2023.
224. Nishijima E, Honda S, Kitamura Y, Namekata K, Kimura A, Guo X, Azuchi Y, Harada C, Murakami A, Matsuda A, Nakano T, Parada LF, Harada T: Vision protection and robust axon regeneration in glaucoma models by membrane- associated Trk receptors. Mol Ther 31:810-24, 2023.
225. Fujio K, Sung J, Hirosawa K, Yamaguchi M, Toshida H, Inagaki K, Ishida G,Itoi M, Sado K, Hayatsu H, Nobutaka H, Ono J, Taniguchi H, Iwagami M, Nagino K, Okumura Y, Midorikawa-Inomata A, Akasaki Y, Huang T, Morooka Y, Okuyama T, Nakao S, Murakami A, Kobayashi H, Inomata T: Effect of antihistamine-releasing contact lenses on ocular symptoms and treatment behavior in patients with seasonal allergic conjunctivitis: A retrospective study. Heliyon 10: e33385, 2024.
226. Goto K, Koyanagi Y, Akiyama M, Murakami Y, Fukushima M, Fujiwara K, Iijima H, Yamaguchi M, Endo M, Hashimoto K, Ishizu M, Hirakata T, Mizobuchi K, Takayama M, Ota J, Sajiki AF, Kominami T, Ushida H, Fujita K, Kaneko H, Ueno S, Hayashi T, Terao C, Hotta Y, Murakami A, Kuniyoshi K, Kusaka S, Wada Y, Abe T, Nakazawa T, Ikeda Y, Momozawa Y, Sonoda KH, Nishiguchi KM: Disease-specific variant interpretation highlighted the genetic findings in 2325 Japanese patients with retinitis pigmentosa and allied diseases. J Med Genet 61: 613-20, 2024.
227. Ari Widjaja S, Mieler WF, Sasono W, Soelistijo SA, Kartasasmita AS, Murakami A, Nakao S: Retinal neurovascular alteration in type 2 diabetes with renal impairment in association with systemic arterial stiffness. Int J Retina Vitreous 10:2, 2024.
228. Akasaki Y, Iwagami M, Sung J, Nagino K, Adachi T, Morita H, Tamari M, Kainuma K, Kan-O K, Ogata H, Sakashita M, Futamura M, Kurashima Y, Nakajima S, Masaki K,Ogawa Y, Sato S, Miyagawa A, Midorikawa-Inomata A, Fujimoto K, Okumura Y, Fujio K, Huang T, Hirosawa K, Morooka Y, Nakao S, Murakami A, Kobayashi H, Inomata T.Impact of COVID-19 on care-seeking patterns for hay fever in Japan: A retrospective claims database cohort study. Allergy 79:1056-1060, 2024
229. Hirosawa K, Inomata T, Akasaki Y, Sung J, Yee A, Iwagami M, Nagino K, Okumura Y, Fujimoto K, Midorikawa-Inomata A, Eguchi A, Shokirova H, Fujio K, Huang T, Morooka Y, Kobayashi H, Murakami A, Nakao S. Impact of the Coronavirus Disease 2019 Pandemic on Outpatient Visits for Diabetic Retinopathy in Japan: A Retrospective Cohort Study. Transl Vis Sci Technol. 2024 Sep 3;13(9):6. doi: 10.1167/tvst.13.9.6. PMID: 39235400; PMCID: PMC11379092.
230,Kuribayashi H, Iwagawa T, Murakami A, Kawamura T, Suzuki Y, Watanabe S. NMNAT1 Is Essential for Human iPS Cell Differentiation to the Retinal Lineage. Invest Ophthalmol Vis Sci. 2024 Oct 1;65(12):37. doi: 10.1167/iovs.65.12.37. PMID: 39446354; PMCID: PMC11512567

英文総説
1.Jin ZB, Hayakawa M, Murakami A, Nao-i N. RCC1-like domain and ORF15: essentials in RPGR gene. Adv Exp Med Biol. 2006;572:29-33. doi: 10.1007/0-387-32442-9_5. PMID: 17249551.
2.Hiratsuka Y, Ono K, Murakami A. Alcohol use and cataract Curr Drug Abuse Rev.;2(3):226-9,2009
3.Murakami　A . Autonomic Nerve Dysfunction in Ocular Diseases. Juntendo Medical Journal 62 377-380, 2016
4.Inomata T, Sung J, Nakamura M, Fujisawa K, Muto K, Ebihara N, Iwagami M, Nakamura M, Fujio K, Okumura Y, Okano M, Murakami A. New medical big data for P4 medicine on allergic conjunctivitis. Allergol Int. 2020 Jul 7:S1323-8930(20)30089-7. doi: 10.1016/j.alit.2020.06.001. Epub ahead of print. PMID: 32651122
5.Okumura Y, Inomata T, Iwata N, Sung J, Fujimoto K, Fujio K, Midorikawa-Inomata A, Miura M, Akasaki Y, Murakami A. A Review of Dry Eye Questionnaires: Measuring Patient-Reported Outcomes and Health-Related Quality of Life. Diagnostics (Basel). 2020 Aug 5;10(8):E559. doi:

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村上 晶（ムラカミ アキラ）

村上晶（ムラカミアキラ）