HOME ＞ 研究業績詳細
研究業績詳細
池嶋 健一（イケジマ ケンイチ）
| 研究テーマ | 脂肪性肝炎の病態と治療に関する基礎的および臨床的検討 |
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| 研究業績（論文） | 1．教育の内容方法の工夫 なし、 2．作成した教科書、教材、参考書等 3．教育方法・教育実践に関する発表、講演等 なし、 4．その他教育活動上突起すべき事項 なし、 5．体育実技に関する事項 なし、 6．業績（著書・論文） 【英文原著】（過去5年） 1. Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N. Hepatic steatosis is a predictor of poor response to interferon alpha-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C. Hepatol. Res. 35(1): 19-25, 2006. 2. Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N. Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-Ay mice. Hepatol. Res. 36: 217-228, 2006. 3. Zheng DM, Kitamura T, Ikejima K, Enomoto N, Yamashina S, Suzuki S, Takei Y, Sato N. Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: role of intracellular calcium and nitric oxide. Hepatology 44: 1278-1287, 2006. 4. Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N. Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat. J. Hepatol. 46: 286-294, 2007. 5. Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N. Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity. J. Gastroenterol. Hepatol. 22(3): 423-428, 2007. 6. Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Frese S, Ikeda H, Haynes N, Cretney E, Yagita H, Sueyoshi N, Sato N, Nakanuma Y, Smyth M, Okumura K. Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease. Proc.Natl.Acad.Sci.USA, 105(31): 10895-10900, 2008. 7. Uchiyama A, Kim JS, Kon K, Jaeschke H, Ikejima K, Watanabe S, Lemasters JJ. Translocation of Iron from Lysosomes into Mitochondria is a Key Event During Oxidative Stress-Induced Hepatocellular Injury. Hepatology 48(5):1644-54, 2008. 8. Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S. Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice. Hepatology 49(5):1636-44, 2009. 9. Takashima M, Parsons CJ, Ikejima K, Watanabe S, White ES, Rippe RA. The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation. J. Gastroenterol. 44(8):847-55, 2009. 10. Piao N, Ikejima K, Kon K, Aoyama T, Osada T, Takei Y, Sato N, Watanabe S. Synthetic triglyceride containing an arachidonic acid branch (8A8) prevents lipopolysaccharide-induced liver injury. Life Sci 85(17-18):617-24, 2009. 11. Mizui T, Yamashina S, Tanida I, Takei Y, Ueno T, Sakamoto N, Ikejima K, Kitamura T, Enomoto N, Sakai T, Kominami E, Watanabe S. Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy. J Gastroenterol 45(2): 195-203, 2010. 12. Kon K, Ikejima K, Okumura K, Arai K, Aoyama T, Watanabe S. Diabetic KK-Ay mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen. Am J Physiol Gastrointest Liver Physiol 299: G329-337, 2010. 13. Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S. CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice. J Hepatol 54(6): 1195-1204, 2010. 14. Wang X, Ikejima K, Kon K, Arai K, Aoyama T, Okumura K, Abe W, Sato N, Watanabe S. Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells. J Hepatol 55(2): 379-87, 2010. |
| 研究者 | 教育活動 |